Guest guest Posted May 28, 2004 Report Share Posted May 28, 2004 Subject: GM_crops_alter_structure_and_function_of_liver,_new_research_shows " GM_WATCH " Thu, 27 May 2004 13:21:07 +0100 GM WATCH http://www.gmwatch.org ------ " The article below is a valuable article. It shows eating GM crops alters structure and function of the liver. " - Prof Joe Cummins ------ Cell Structure and Function Vol. 27 (2002) , No. 4 pp.173-18 Ultrastructural Morphometrical and Immunocytochemical Analyses of Hepatocyte Nuclei from Mice Fed on Genetically Modified Soybean Manuela Malatesta1), Chiara Caporaloni1)2), Stefano Gavaudan2), Marco B.L. Rocchi3), Sonja Serafini4), Cinzia Tiberi1) and Giancarlo Gazzanelli1) 1) Istituto di Istologia e Analisi di Laboratorio, via Zeppi s.n., University of Urbino 2) Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche 3) Istituto di Biomatematica, Località Crocicchia, University of Urbino 4) Istituto di Chimica Biologica " G. Fornaini " , via Saffi 2, University of Urbino ABSTRACT. No direct evidence that genetically modified (GM) food may represent a possible danger for health has been reported so far; however, the scientific literature in this field is still quite poor. Therefore, we carried out an ultrastructural morphometrical and immunocytochemical study on hepatocytes from mice fed on GM soybean, in order to investigate eventual modifications of nuclear components of these cells involved in multiple metabolic pathways related to food processing. Our observations demonstrate significant modifications of some nuclear features in GM-fed mice. In particular, GM fed-mice show irregularly shaped nuclei, which generally represents an index of high metabolic rate, and a higher number of nuclear pores, suggestive of intense molecular trafficking. Moreover, the roundish nucleoli of control animals change in more irregular nucleoli with numerous small fibrillar centres and abundant dense fibrillar component in GM-fed mice, modifications typical of increased metabolic rate. Accordingly, nucleoplasmic (snRNPs and SC- 35) and nucleolar (fibrillarin) splicing factors are more abundant in hepatocyte nuclei of GM-fed than in control mice. In conclusion, our data suggest that GM soybean intake can influence hepatocyte nuclear features in young and adult mice; however, the mechanisms responsible for such alterations remain unknown. ykcul_ritsym <ykcul_ritsym wrote: At the risk of offending everyone. I am the TCM Czar. I invented traditional medicine. I am the spinning sword goddess. I heal thousands in a second with my love thoughts. It is my fault the world is suffering so much because I have not perfected myself. I need more gold than cortez. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 28, 2004 Report Share Posted May 28, 2004 Frankenfoods, soy products, processed foods: garbage, pure and simple. And all the " value added " in these foods go right to the antichrist multinationals, and out of your community. Soy is a chelator of many nutrients your body needs-sadly, the soy pulls out many of the nutrients you're using it for. Soy has been foisted upon the U.S. by big business, who first tried to sell it to the " poor people, " but then, after THAT failed, went after the yuppie/ high income market. Soy is a ploy!!!!!! Processed foods: remember a good rule of thumb: long shelf life= short human life. JG --- ykcul_ritsym <ykcul_ritsym wrote: > > > Subject: > GM_crops_alter_structure_and_function_of_liver,_new_research_shows > " GM_WATCH " > Thu, 27 May 2004 13:21:07 +0100 > > GM WATCH > http://www.gmwatch.org > ------ > " The article below is a valuable article. It shows > eating GM crops > alters structure and function of the liver. " - Prof > Joe Cummins > ------ > Cell Structure and Function > Vol. 27 (2002) , No. 4 pp.173-18 > > Ultrastructural Morphometrical and > Immunocytochemical Analyses of > Hepatocyte Nuclei from Mice Fed on Genetically > Modified Soybean > > Manuela Malatesta1), Chiara Caporaloni1)2), Stefano > Gavaudan2), Marco > B.L. Rocchi3), Sonja Serafini4), Cinzia Tiberi1) and > Giancarlo > Gazzanelli1) > > 1) Istituto di Istologia e Analisi di Laboratorio, > via Zeppi s.n., > University of Urbino > 2) Istituto Zooprofilattico Sperimentale dell'Umbria > e delle Marche > 3) Istituto di Biomatematica, Località Crocicchia, > University of > Urbino > 4) Istituto di Chimica Biologica " G. Fornaini " , via > Saffi 2, > University > of Urbino > > ABSTRACT. No direct evidence that genetically > modified (GM) food may > represent a possible danger for health has been > reported so far; > however, the scientific literature in this field is > still quite poor. > Therefore, we carried out an ultrastructural > morphometrical and > immunocytochemical study on hepatocytes from mice > fed on GM soybean, > in order to investigate eventual modifications of > nuclear components > of these cells involved in multiple metabolic > pathways related to > food processing. Our observations demonstrate > significant > modifications of some nuclear features in GM-fed > mice. In particular, > GM fed-mice show irregularly shaped nuclei, which > generally > represents an index of high metabolic rate, and a > higher number of > nuclear pores, suggestive of intense molecular > trafficking. Moreover, > the roundish nucleoli of control animals change in > more irregular > nucleoli with numerous small fibrillar centres and > abundant dense > fibrillar component in GM-fed mice, modifications > typical of > increased metabolic rate. Accordingly, nucleoplasmic > (snRNPs and SC- > 35) and nucleolar (fibrillarin) splicing factors are > more abundant in > hepatocyte nuclei of GM-fed than in control mice. > In conclusion, our data suggest that GM soybean > intake can influence > hepatocyte nuclear features in young and adult mice; > however, the > mechanisms responsible for such alterations remain > unknown. > > > > ykcul_ritsym <ykcul_ritsym wrote: > At the risk of offending everyone. I am the TCM > Czar. I invented > traditional medicine. I am the spinning sword > goddess. I heal > thousands in a second with my love thoughts. It is > my fault the > world is suffering so much because I have not > perfected myself. > I need more gold than cortez. > > > Friends. Fun. Try the all-new Messenger. http://messenger./ Quote Link to comment Share on other sites More sharing options...
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