Guest guest Posted April 29, 2004 Report Share Posted April 29, 2004 Hello, ANd so why aren't people given cod liver oil FIRST? THis not only keeps the platelets slipery, supplies needed nutrients to the brain/eyes/cell membranes to keep them healthy, is antiinflamatory AND it doesn't stop/change the coagulation actions of one's blood. In addition, one doesn't need to worry about the life-threatening side effects of brain hemorage as when one takes coumadin/warfarin. . . I vote for c.l.o. . . Susan Froehlich. LAc Hood River, OR USA Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2004 Report Share Posted April 29, 2004 Hi All, See abstract, below. It suggests that fish oil may provide additive anticoagulant effects when given with warfarin. Best regards, Phil >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> Fish oil interaction with warfarin. Buckley, MS; Goff, AD; Knapp, WE Annals of Pharmacotherapy (USA) VOL. 38 NO. 1, 2004, 50- 53. Shawnee Mission Med Ctr, Shawnee Mission, KS, USA OBJECTIVE: To report a case of elevated international normalized ratio (INR) in a patient taking fish oil and warfarin. CASE SUMMARY: A 67-year-old white woman had been taking warfarin for 1 1/2 years due to recurrent transient ischemic attacks. Her medical history included hypothyroidism, hyperlipidemia, osteopenia, hypertension, and coronary artery disease. She also experienced an inferior myocardial infarction in 1995 requiring angioplasty, surgical repair of her femoral artery in 1995, and hernia repair in 1996. This patient has her INR checked in the anticoagulation clinic and is followed monthly by the clinical pharmacist. Prior to the interaction, her INR was therapeutic for 5 months while she was taking warfarin 1.5 mg/d. The patient admitted to doubling her fish oil dose from 1000 to 2000 mg/d. Without dietary, lifestyle, or medication changes, the INR increased from 2.8 to 4.3 within 1 month. The INR decreased to 1.6 one week after subsequent fish oil reduction, necessitating a return to the original warfarin dosing regimen. DISCUSSION: Fish oil supplementation could have provided additional anticoagulation with warfarin therapy Fish oil, an omega-3 polyunsaturated fatty acid, consists of eicosapentaenoic acid and docosahexaenoic acid. This fatty acid may affect platelet aggregation and/or vitamin K-dependent coagulation factors. Omega-3 fatty acids may lower thromboxane A<INF>2</INF> supplies within the platelet as well as decrease factor VII levels. Although controversial, this case report illustrates that fish oil can provide additive anticoagulant effects when given with warfarin. CONCLUSIONS: This case reveals a significant rise in INR after the dose of concomitant fish oil was doubled. Patients undergoing anticoagulation therapy with warfarin should be educated about and monitored for possible drug-herb interactions. Pharmacists can play a crucial role in identifying possible drug interactions by asking patients taking warfarin about herbal and other alternative medicine product use. Best regards, Email: < WORK : Teagasc Research Management, Sandymount Ave., Dublin 4, Ireland Mobile: 353-; [in the Republic: 0] HOME : 1 Esker Lawns, Lucan, Dublin, Ireland Tel : 353-; [in the Republic: 0] WWW : http://homepage.eircom.net/~progers/searchap.htm Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2004 Report Share Posted April 30, 2004 , " " <@e...> wrote: > Hi All, > > See abstract, below. It suggests that fish oil may provide additive > anticoagulant effects when given with warfarin. > possibly more evidence that fish oil has similar effects (and possible interactions) as other blood moving herbs? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2004 Report Share Posted April 30, 2004 Interesting point. What would the world be like if DR's recommended food as the first choice in disease control??? How many lives would be saved? How quickly would the news spred? How would the lifestyle of people change? I think after generation, personal responsibility would be the norm and people would support each other in the journey for health. Chris in In a message dated 4/30/2004 3:11:02 AM Eastern Daylight Time, SusFro writes: Hello, ANd so why aren't people given cod liver oil FIRST? THis not only keeps the platelets slipery, supplies needed nutrients to the brain/eyes/cell membranes to keep them healthy, is antiinflamatory AND it doesn't stop/change the coagulation actions of one's blood. In addition, one doesn't need to worry about the life-threatening side effects of brain hemorage as when one takes coumadin/warfarin. . . I vote for c.l.o. . . Susan Froehlich. LAc Hood River, OR USA Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.