Eli Lilly buys out TCM

[Guest guest]

http://www.telegraph.co.uk/money/main.jhtml?xml=/money/2007/08/20/cneli120.xml & D\

CMP=ILC-traffdrv07053100

 

Eli Lilly turns to Chi-Med

By Mark Kleinman in Hong Kong

20/08/2007

 

Eli Lilly, the global pharmaceuticals giant behind

blockbuster drugs including the anti-depressant

Prozac, is turning to ancient Chinese remedies for a

new pipeline of treatments.

The partnership may help improve the image of Chinese

medicines in the West

 

Hutchison China Meditech (Chi-Med), the AIM-listed

subsidiary of Hong Kong conglomerate Hutchison

Whampoa, will announce today that it has struck a drug

discovery and development partnership with Eli Lilly,

which is based in New York.

 

The tie-up will see Hutchison Medipharma, Chi-Med's

research and development arm, paid up to $29m in

so-called " milestone fees " for each drug candidate

developed from the company's vast collection of herbal

compounds. Chi-Med will also gain an undisclosed

up-front payment and annual research and development

fees from its US partner.

 

Dr William Chin, vice-president of discovery research

and clinical investigation for Eli Lilly, said: " We

are excited to explore this innovative research

collaboration model. "

 

The agreement will initially focus on developing

treatments in the areas of oncology and inflammation,

with Chi-Med responsible for identifying candidates

for clinical trial and Eli Lilly providing technical

advice and subsequent development activities. For

Chi-Med, the partnership may provide a much-needed

boost to its beleaguered share price and help improve

the image of Chinese medicines in the West.

advertisement

 

The company, which listed its shares at 275p when it

floated on AIM last year, has seen its stock price

drift steadily downward despite announcing deals with

Merck, the German pharmaceuticals firm, and Procter &

Gamble, a partnership that involves P & G developing

health and beauty products from Chi-Med compounds.

Hutchison Whampoa, which is chaired by Li Ka-shing,

Asia's richest man, retains a 72pc stake in Chi-Med.

 

Chi-Med's share price failed to move significantly

even after announcing positive results from Phase-II

trials of a treatment for ulcerative colitis and

Crohn's disease earlier this year.

 

News of the deal with Eli Lilly comes as China's

pharmaceuticals industry is battling to rescue its

reputation in the wake of a series of incidents which

have exposed a large quantity of counterfeit medicines

being exported from China.

 

Today's announcement is also expected to point to the

benefits of conducting drug R & D in China, where

multinational firms are able to leverage the country's

low cost-base and a growing contingent of qualified

scientists.

 

copyright of Telegraph Media Group Limited

[Guest guest]

Chinese Traditional Medicine , dar <dobbie606 wrote:

>

> http://www.telegraph.co.uk/money/main.jhtml?

xml=/money/2007/08/20/cneli120.xml & DCMP=ILC-traffdrv07053100

>

> Eli Lilly, the global pharmaceuticals giant behind

> blockbuster drugs including the anti-depressant

> Prozac, is turning to ancient Chinese remedies for a

> new pipeline of treatments.

> The partnership may help improve the image of Chinese

> medicines in the West

 

Or worsen it as the case may be.

 

> The tie-up will see Hutchison Medipharma, Chi-Med's

> research and development arm, paid up to $29m in

> so-called " milestone fees " for each drug candidate

> developed from the company's vast collection of herbal

> compounds. Chi-Med will also gain an undisclosed

> up-front payment and annual research and development

> fees from its US partner.

 

These people simply do not get it. What makes something TCM is not

that an herb is grown in China but the way it is used. Using an herb

(or a food or a prescription drug or supplements or needles or

whatever) within a TCM framework is what makes something TCM.

 

Above all else TCM takes a holistic view of healing. How everything

works (or doesn't work) together. The moment companies start

isolating what they consider to be " active ingredients " in order to

treat one specific symptom or illness, it ceases to be TCM. Some of

the so-called inert or not significant ingredients often turn out to

be something that is important.

 

Allopathic medicine (and businesses) in the West have a long history

of thinking they know more than they do. One of the best examples is

the dicovery of and manufacturing of synthetic vitamin C. Vitamin C

did not work as well as researchers originally had predicted. As it

turned out, some of the effects of natural vitamin C were not coming

from vitamin C but from compounds called bioflavanoids which occur

with vitamin C when the vitamin is obtained from natural sources.

 

Western research also rarely considers cases where compounds work

together, prefering instead to concentrate on identifying and testing

one particular chemical at a time. The exception to this has been in

the field of research into vitamins and minerals - though said

realizations usually came years and even decades after the discovery

of the role of the vitamin or mineral in good health. A prime example

is that oral administration of vitamin B12 is useless in treating

prenicious anemia because people with this condition lack something

called " instrinsic factor " which is needed to absorb vitamin B12.

Another example is that the body needs calcium in order to be able to

absorb magnesium and vice versa (though after this point is reached

the two are in competition with each other). Another example is how

vitamin C improves the absorption of iron. Etc.

 

All these things were discovered years after the original

discoveries. In contrast TCM takes it as a given that things work

together holistically.

 

Another problem with isolating compounds from herbs is that it

ignores contraindications. It ignores balance. Under every single

herbal entry in the Chinese Materia Medica (list of healing

substances), one will see a section on cautions and

contraindications. For example, Yang Tonic herbs can worsen Yin

Deficiency and vice versa. Qi Tonic herbs given to a person who also

has Qi Stagnation problems can worsen the Stagnation problems. Etc.

 

Finally, this mass market approach ignores something that is very

critical to TCM: What TCM treats are TCM imbalances, not allopathic-

defined medical conditions. One of the biggest surprises about TCM

to many Westerners is that the same allopathic-defined medical

condition can have one or more of several possible TCM imbalances

underlying it. For example, what helps one asthmatic may do nothing

for a second and can even worsen the asthma of a third because the

TCM " Roots " are different.

 

What these pharmaceutical companies are doing is NOT TCM. It's the

same old same old approach that in the West not only has reached the

point of diminishing returns but of hurting more and more people.

[Guest guest]

Victoria,

 

I was thinking the same thing as I read that article... this is not

limited to TCM, there is a push from these drug companies to muscle in

on the alternative medicine " market " by using their powerful political

influence with oversight agencies to come up with " regulation " aimed at

forcing smaller companies, who haven't got the financial resources or

regulatory experience, to either go under or form alliances with them in

order to survive!

 

If you ask me, I see nothing being able to stop them from taking over!

Money moves everything in the world these days and it behooves each of

us to do everything we can on a personal basis to maintain health by

life style and other means of cultivation rather than looking for

correct imbalances after they occur, after all, they cannot regulate

that... yet!

 

Domingo

 

victoria_dragon wrote:

>

> Chinese Traditional Medicine

> <Chinese Traditional Medicine%40>, dar <dobbie606 wrote:

> >

> > http://www.telegraph.co.uk/money/main.jhtml?

> <http://www.telegraph.co.uk/money/main.jhtml?>

> xml=/money/2007/08/20/cneli120.xml & DCMP=ILC-traffdrv07053100

> >

> > Eli Lilly, the global pharmaceuticals giant behind

> > blockbuster drugs including the anti-depressant

> > Prozac, is turning to ancient Chinese remedies for a

> > new pipeline of treatments.

> > The partnership may help improve the image of Chinese

> > medicines in the West

>

> Or worsen it as the case may be.

>

> > The tie-up will see Hutchison Medipharma, Chi-Med's

> > research and development arm, paid up to $29m in

> > so-called " milestone fees " for each drug candidate

> > developed from the company's vast collection of herbal

> > compounds. Chi-Med will also gain an undisclosed

> > up-front payment and annual research and development

> > fees from its US partner.

>

> These people simply do not get it. What makes something TCM is not

> that an herb is grown in China but the way it is used. Using an herb

> (or a food or a prescription drug or supplements or needles or

> whatever) within a TCM framework is what makes something TCM.

>

> Above all else TCM takes a holistic view of healing. How everything

> works (or doesn't work) together. The moment companies start

> isolating what they consider to be " active ingredients " in order to

> treat one specific symptom or illness, it ceases to be TCM. Some of

> the so-called inert or not significant ingredients often turn out to

> be something that is important.

>

> Allopathic medicine (and businesses) in the West have a long history

> of thinking they know more than they do. One of the best examples is

> the dicovery of and manufacturing of synthetic vitamin C. Vitamin C

> did not work as well as researchers originally had predicted. As it

> turned out, some of the effects of natural vitamin C were not coming

> from vitamin C but from compounds called bioflavanoids which occur

> with vitamin C when the vitamin is obtained from natural sources.

>

> Western research also rarely considers cases where compounds work

> together, prefering instead to concentrate on identifying and testing

> one particular chemical at a time. The exception to this has been in

> the field of research into vitamins and minerals - though said

> realizations usually came years and even decades after the discovery

> of the role of the vitamin or mineral in good health. A prime example

> is that oral administration of vitamin B12 is useless in treating

> prenicious anemia because people with this condition lack something

> called " instrinsic factor " which is needed to absorb vitamin B12.

> Another example is that the body needs calcium in order to be able to

> absorb magnesium and vice versa (though after this point is reached

> the two are in competition with each other). Another example is how

> vitamin C improves the absorption of iron. Etc.

>

> All these things were discovered years after the original

> discoveries. In contrast TCM takes it as a given that things work

> together holistically.

>

> Another problem with isolating compounds from herbs is that it

> ignores contraindications. It ignores balance. Under every single

> herbal entry in the Chinese Materia Medica (list of healing

> substances), one will see a section on cautions and

> contraindications. For example, Yang Tonic herbs can worsen Yin

> Deficiency and vice versa. Qi Tonic herbs given to a person who also

> has Qi Stagnation problems can worsen the Stagnation problems. Etc.

>

> Finally, this mass market approach ignores something that is very

> critical to TCM: What TCM treats are TCM imbalances, not allopathic-

> defined medical conditions. One of the biggest surprises about TCM

> to many Westerners is that the same allopathic-defined medical

> condition can have one or more of several possible TCM imbalances

> underlying it. For example, what helps one asthmatic may do nothing

> for a second and can even worsen the asthma of a third because the

> TCM " Roots " are different.

>

> What these pharmaceutical companies are doing is NOT TCM. It's the

> same old same old approach that in the West not only has reached the

> point of diminishing returns but of hurting more and more people.

>

>

 

 

 

[Guest guest]

Chinese Traditional Medicine , Domingo Pichardo

<dpichardo3 wrote:

> If you ask me, I see nothing being able to stop them from taking

over!

> Money moves everything in the world these days and it behooves each

of

> us to do everything we can on a personal basis to maintain health by

> life style and other means of cultivation rather than looking for

> correct imbalances after they occur, after all, they cannot regulate

> that... yet!

 

The only thing I know of that can stop them is to get the word out to

as many people as one can that this is NOT TCM and that people are

being shortchanged and even denied real TCM help by this being passed

off as being related to TCM. Getting the word out is slow, but I can't

think of any other way to stop this misuse and misinformation.

 

Victoria

[Guest guest]

Re: Eli Lilly buys out TCM

 

--- In

Chinese Traditional Medicine , " victoria_dragon "

wrote:

 

 

The only thing I know of that can stop them is to get

the word out to

as many people as one can that this is NOT TCM and

that people are

being shortchanged and even denied real TCM help by

this being passed

off as being related to TCM. Getting the word out is

slow, but I can't

think of any other way to stop this misuse and

misinformation.

Victoria ----

 

G'day TCMers,

-Rbt Cohen tries valiantly to awaken the slumbering

masses & now Dr.Victoria has urged us to join the fray.

Alas, we may not be able to do this for long.It seems

implants are much more insidious than we can imagine:

http://www.us-government-torture.com/

 

cheers,

dar

 

One Reason For My Continuing Insanity

by Robert Cohen

 

I have not previously written about this factor...

it is giving me nightmares.

 

In 1990, I helped a 60 Minutes producer (Isadore

Roesemarin) do

a segment on aspartame/NutraSwee t, the artificial

sweetener.

When Searle Pharmaceuticals got NutraPoison approved,

their

president was a man by the name of Donald Rumsfeld.

They then

sold the company to Monsanto. A 30-year-old named

Clarence

Thomas was then Monsanto's lawyer. A congressman by

the name

of John Ashcroft had received the greatest number of

political

donations from Monsanto. That's just a bit of trivia

and

not the primary point to be made here...

 

At that time I carefully went through Searle's

research. They

had submitted 112 studies to the FDA for approval. The

FDA

designated 17 of those studies to be " pivotal. " By

naming

a study " pivital " it had to be available to the public

in its

entirety. So...I filed a Freedom of Information Act

request for

the 17 studies. One of them was performed at the

University

of Wisconsin on Rhesus Monkeys. After day 300 of that

one-year

study every single one of the monkeys (low dose,

medium dose,

and high dose groups) developed grand mal epileptic

seizures.

 

Although I totally reject animal research, I recognize

that the performance and review of such research is

THEIR

game. THEY set the criteria. When lab animals suffer

adverse affects, THEY are responsible for telling the

truth.

In this case, THEY ignored the truth. I discovered the

truth.

 

One month before the report aired, I met with a man by

the

name of Michael Friedman, a high level FDA bureaucrat.

I shared

the results of the study with him. FDA had approved

aspartame

by concluding that there were no adverse affects on

laboratory

animals. I found that FDA had erred. Friedman had my

information.

 

I also found an ex-FDA employee willing to testify

regarding

internal FDA pressures to ignore the facts and approve

NutraSweet.

There was fraud and deceit at FDA. The public was

about to be

intentionally poisoned.

 

When the actual 60 Minutes piece aired, they left the

testimony

of the FDA employee on the cutting room floor.

Furthermore,

Friedman, armed with my information, was interviewed

and said,

" There were no adverse affects on lab animals. " He

lied and

I was angry and disappointed. The man represented pure

evil

to me.

 

Three months later he was named FDA Commissioner.

Six months after that he left FDA to become the new

president of the NutraSweet company.

 

Now, I get to the real point of my story.

 

While I was addicted to Oxycontin, the FDA fined

the manufacturer, Purdue Pharmaceuticals, $634 million

 

for deceptive practices... for not revealing that

Oxycontin was more addictive than heroin. This week

after weaning myself from this powerful drug, I

learned

that the acting president of that company is the very

same Michael Friedman.

 

I live in a world of conspiracy theories, and I do

too much research for my own good. The paper trails

seem impossible for investigative reporters to

follow, while they are marked with day-glo paint

for me. Call it my curse. I do what I do for the

public, I guess. I keep no secrets. I immediately

write about them. Perhaps, in a conspiracy theory

world, that is what keeps me alive. I do not really

give a damn any more about my safety. Their crimes

against mankind are so serious that I must do what

I do.

 

My Woodstock generation.. .we were going to change the

 

world, remember? Remember our phony ideals and how

everybody we know sold out and became our own parents?

 

Am I just wasting my time?

 

Robert Cohen

i4crob (AT) earthlink (DOT) net

www.notmilk.com