Study: Inositol Hexaphosphate (IP6) effective against bladder cancer

November 29, 2009

Inositol Hexaphosphate (IP6): Modulation of Cell Cycle and Proliferation of Bladder Cancer in vitroStanley Zaslau, Dale R. Riggs, Barbara J. Jackson, Can Talug, Stanley J. KandzariSection of Urology, Department Of Surgery, Robert C. Byrd Health Science Center, West Virginia University, Morgantown, W. Va., USA

Address of Corresponding Author

Curr Urol 2009;3:136-140 (DOI: 10.1159/000253371)

Introduction: We hypothesized that inositol hexaphosphate (IP6) would modulate cell cycle and cellular growth in bladder cancer. Materials and Methods: Bladder cancer cell lines were treated with 2.5 or 4.5 mM/well IP6. Cell viability was measured by MTT at 24 and 48 h. Cell cycle analysis was measured by DNA staining and quantified by FACS analysis. Results: Cell growth was inhibited in the TCCSUP, HTB9 and T24 cells (p < 0.001) with the exception of the HTB9 cells at 24 h. G1 phase fractions increased in the TCCSUP and HTB9 cells, while S phase fraction was decreased (p < 0.001). G2 phase was decreased in the TCCSUP cells (p < 0.001). G1 phase fraction was decreased in the T24 line with 4.5 mMIP6 (p < 0.001), while a significant increase in the S phase was observed in the T24 cells (p < 0.001). Conclusions: These results indicate that IP6 is potentially a highly effective treatment for carcinoma of the bladder.

Copyright Â© 0090 S. Karger AG, Basel

Tony's Note: Inositol and inositol hexaphosphate (IP6) have been found to be effective against several forms of cancer, including prostate cancer - which is why it is recommended as an essential element in the suggested anti-cancer protocol .

November 30, 2009

Thank you Tony, for this citation. I notice on the Anti-Cancer Protocol, you

don't recommend being on the intensive dosing of IP6 for more than a few months.

I realize that some things don't lend themselves to great precision- but is a

few months two? three?

Mukki started this back in mid-August at a maintenance level and we most likely

upped it to the intense dose (4 caps, 2x/day) at the start of September so he'd

have been on it for 3 months now.

Do you recommend a full stop? And then in a few weeks, back to a maintenance

level of 2 caps, 2x/day? Or a switch to maintenance level now without a break?

We just recently re-started Sutherlandia OPC (2 days ago) and I know that Marc

recommends using this in conjunction with IP6/Inositol. We are using the Cell

Forte brand.

My thanks,

Christina

oleander soup , "" wrote:

>

> Inositol Hexaphosphate (IP6): Modulation of Cell Cycle and Proliferation

> of Bladder Cancer in vitro

> Stanley Zaslau, Dale R. Riggs, Barbara J. Jackson, Can Talug, Stanley J.

> Kandzari

>

> Section of Urology, Department Of Surgery, Robert C. Byrd Health Science

> Center, West Virginia University, Morgantown, W. Va., USA

>

> Address of Corresponding Author

> <http://content.karger.com/produktedb/produkte.asp?doi=253371#AC>

>

> Curr Urol 2009;3:136-140 (DOI: 10.1159/000253371)

>

> Introduction: We hypothesized that inositol hexaphosphate (IP6) would

> modulate cell cycle and cellular growth in bladder cancer. Materials and

> Methods: Bladder cancer cell lines were treated with 2.5 or 4.5 mM/well

> IP6. Cell viability was measured by MTT at 24 and 48 h. Cell cycle

> analysis was measured by DNA staining and quantified by FACS analysis.

> Results: Cell growth was inhibited in the TCCSUP, HTB9 and T24 cells (p

> < 0.001) with the exception of the HTB9 cells at 24 h. G1 phase

> fractions increased in the TCCSUP and HTB9 cells, while S phase fraction

> was decreased (p < 0.001). G2 phase was decreased in the TCCSUP cells (p

> < 0.001). G1 phase fraction was decreased in the T24 line with 4.5 mMIP6

> (p < 0.001), while a significant increase in the S phase was observed in

> the T24 cells (p < 0.001). Conclusions: These results indicate that IP6

> is potentially a highly effective treatment for carcinoma of the

> bladder.

>

> Copyright Â© 0090 S. Karger AG, Basel

>

> Tony's Note: Inositol and inositol hexaphosphate (IP6) have been found

> to be effective against several forms of cancer, including prostate

> cancer - which is why it is recommended as an essential element in the

> suggested anti-cancer protocol </anticancer.htm> .

>

December 1, 2009

I believe one good source of inositol is freshly harvested sap of the coconut

florescence/flower.

Melly