Guest guest Posted November 5, 2009 Report Share Posted November 5, 2009 Zocor is a statin drug and falls into the same category as the other drugs described in my previous post. It has the same serious side effects. If it were me, I would not take it.My Best, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2009 Report Share Posted November 6, 2009 I do realize that it is a statin drug but the research seems to show that it has a positive effect on killing cancer cells, so what are the negative effects that you are referring to? - May oleander soup Thursday, November 05, 2009 4:30 PM Re: Re: Statins/Zocor/Nili Zocor is a statin drug and falls into the same category as the other drugs described in my previous post. It has the same serious side effects. If it were me, I would not take it.My Best, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2009 Report Share Posted November 6, 2009 Hi Nili,I am going to copy and paste part of a reply I made to a previous post just the other day. These are the side effects:Muscle weaknessNeuropathyHeart FailureDizzinessCognitive ImpairementCancerPancreatitisDepressionThe muscle weakness is extremely dangerous, as it is life threatening. It doesn't merely "weaken" muscles, it causes them to waste away, including the skeletal muscles.Are they saying that just Zocor kills cancer cells, or together with another drug, such as Interferon? If this is the case, this is another dangerous drug. It causes autoimmune disorders, damages the bone marrow, and causes serious bone pain. I question whether Zocor or any other statin does indeed kill cancer cells, or whether it's just another way of marketing this drug. Regardless, statins are extremely dangerous and have the capability of doing irreperable harm to one's body. By the way, one of the side effects of statins is that they cause cancer.Below is a link that will give more information on the dangers of statins.http://www.mercola.com/article/statins.htm My Best, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2009 Report Share Posted November 6, 2009 My friend's husband died a miserable death recently after 3 years on a statin drug. The extreme muscle weakness finally put him bed-ridden and helpless as a baby, totally dependent on his wife for every little thing. A host of other statin-related health problems plagued him before he mercifully died. One more pharma-trusting soul killed by the "cure".Betsy May <luellamay129oleander soup Sent: Fri, November 6, 2009 11:59:09 AMRe: Re: Statins/Zocor/Nili Hi Nili,I am going to copy and paste part of a reply I made to a previous post just the other day. These are the side effects:Muscle weaknessNeuropathyHeart FailureDizzinessCognitive ImpairementCancerPancreatitisDepressionThe muscle weakness is extremely dangerous, as it is life threatening. It doesn't merely "weaken" muscles, it causes them to waste away, including the skeletal muscles.Are they saying that just Zocor kills cancer cells, or together with another drug, such as Interferon? If this is the case, this is another dangerous drug. It causes autoimmune disorders, damages the bone marrow, and causes serious bone pain. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 6, 2009 Report Share Posted November 6, 2009 Louella, thank you for all your information and I will definitely discuss it with the doctor who prescribed it who by the way is a very respected authority on alternative and complimentary cancer care. As pointed out in the article published in PubMed HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis. Wong WW, Dimitroulakos J, Minden MD, Penn LZ. Department of Cellular and Molecular Biology, Ontario Cancer Institute, Princess Margaret Hospital, University Health Network, Toronto, Canada. The statin family of drugs target HMG-CoA reductase, the rate-limiting enzyme of the mevalonate pathway, and have been used successfully in the treatment of hypercholesterolemia for the past 15 years. Experimental evidence suggests this key biochemical pathway holds an important role in the carcinogenic process. Moreover, statin administration in vivo can provide an oncoprotective effect. Indeed, in vitro studies have shown the statins can trigger cells of certain tumor types, such as acute myelogenous leukemia, to undergo apoptosis in a sensitive and specific manner. Mechanistic studies show bcl-2 expression is down-regulated in transformed cells undergoing apoptosis in response to statin exposure. In addition, the apoptotic response is in part due to the depletion of the downstream product geranylgeranyl pyrophosphate, but not farnesyl pyrophosphate or other products of the mevalonate pathway including cholesterol. Clinically, preliminary phase I clinical trials have shown the achievable plasma concentration corresponds to the dose range that can trigger apoptosis of tumor types in vitro. Moreover, little toxicity was evident in vivo even at high concentrations. Clearly, additional clinical trials are warranted to further assess the safety and efficacy of statins as novel and immediately available anti-cancer agents. In this article, the experimental evidence supporting a role for the statin family of drugs to this new application will be reviewed. PMID: 11960327 [PubMed - indexed for MEDLINE] - May oleander soup Friday, November 06, 2009 12:59 PM Re: Re: Statins/Zocor/Nili Hi Nili,I am going to copy and paste part of a reply I made to a previous post just the other day. These are the side effects:Muscle weaknessNeuropathyHeart FailureDizzinessCognitive ImpairementCancerPancreatitisDepressionThe muscle weakness is extremely dangerous, as it is life threatening. It doesn't merely "weaken" muscles, it causes them to waste away, including the skeletal muscles.Are they saying that just Zocor kills cancer cells, or together with another drug, such as Interferon? If this is the case, this is another dangerous drug. It causes autoimmune disorders, damages the bone marrow, and causes serious bone pain. I question whether Zocor or any other statin does indeed kill cancer cells, or whether it's just another way of marketing this drug. Regardless, statins are extremely dangerous and have the capability of doing irreperable harm to one's body. By the way, one of the side effects of statins is that they cause cancer.Below is a link that will give more information on the dangers of statins.http://www.mercola.com/article/statins.htm My Best, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2009 Report Share Posted November 8, 2009 Lovastatin has been shown to be especially active in its anti cancer activity. It was originally isolated from an edible mushroom and is found in red rice yeast (RRY). Some studies show that RRY is more effective than the synthetic form of Lovastatin, probably due to its content of associated isomers. It is important to take gamma vitamin E along with RRY since it greatly enhances its activity and I think it is critical to add Co-Q10 to any statin to overcome some of the potential side effects---especially with muscles. I agree that high cholesterol is not as a serious a condition as modern medicine would have us believe and I have resisted using statins even though my doctor has recommended their use and issued prescriptions. He has never been able to explain why just as many people die of heart attacks with normal or low levels of cholesterol as those with high levels. There are exceptions where people have a genetic predisposition to very high cholesterol levels. However, we are talking about controlling cancer, not cholesterol and I think one needs as many bullets in the gun as is available and hit cancer cells from as many metabolic pathways as is possible and RRY hits an important pathway for cancer cell survival and I will use it daily. So far, my tumors have been shrinking and if and when they are controlled, I will probably stop using RRY. Bob R oleander soup oleander soup On Behalf Of Nili Gitig Friday, November 06, 2009 5:50 PM oleander soup Re: Re: Statins/Zocor/Nili Louella, thank you for all your information and I will definitely discuss it with the doctor who prescribed it who by the way is a very respected authority on alternative and complimentary cancer care. As pointed out in the article published in PubMed HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis. Wong WW, Dimitroulakos J, Minden MD, Penn LZ. Department of Cellular and Molecular Biology, Ontario Cancer Institute, Princess Margaret Hospital, University Health Network, Toronto, Canada. The statin family of drugs target HMG-CoA reductase, the rate-limiting enzyme of the mevalonate pathway, and have been used successfully in the treatment of hypercholesterolemia for the past 15 years. Experimental evidence suggests this key biochemical pathway holds an important role in the carcinogenic process. Moreover, statin administration in vivo can provide an oncoprotective effect. Indeed, in vitro studies have shown the statins can trigger cells of certain tumor types, such as acute myelogenous leukemia, to undergo apoptosis in a sensitive and specific manner. Mechanistic studies show bcl-2 expression is down-regulated in transformed cells undergoing apoptosis in response to statin exposure. In addition, the apoptotic response is in part due to the depletion of the downstream product geranylgeranyl pyrophosphate, but not farnesyl pyrophosphate or other products of the mevalonate pathway including cholesterol. Clinically, preliminary phase I clinical trials have shown the achievable plasma concentration corresponds to the dose range that can trigger apoptosis of tumor types in vitro. Moreover, little toxicity was evident in vivo even at high concentrations. Clearly, additional clinical trials are warranted to further assess the safety and efficacy of statins as novel and immediately available anti-cancer agents. In this article, the experimental evidence supporting a role for the statin family of drugs to this new application will be reviewed. PMID: 11960327 [PubMed - indexed for MEDLINE] ----- Original Message ----- May oleander soup Friday, November 06, 2009 12:59 PM Re: Re: Statins/Zocor/Nili Hi Nili, I am going to copy and paste part of a reply I made to a previous post just the other day. These are the side effects: Muscle weakness Neuropathy Heart Failure Dizziness Cognitive Impairement Cancer Pancreatitis Depression The muscle weakness is extremely dangerous, as it is life threatening. It doesn't merely " weaken " muscles, it causes them to waste away, including the skeletal muscles. Are they saying that just Zocor kills cancer cells, or together with another drug, such as Interferon? If this is the case, this is another dangerous drug. It causes autoimmune disorders, damages the bone marrow, and causes serious bone pain. I question whether Zocor or any other statin does indeed kill cancer cells, or whether it's just another way of marketing this drug. Regardless, statins are extremely dangerous and have the capability of doing irreperable harm to one's body. By the way, one of the side effects of statins is that they cause cancer. Below is a link that will give more information on the dangers of statins. http://www.mercola.com/article/statins.htm My Best, Quote Link to comment Share on other sites More sharing options...
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