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I find this article very intresting, so i'm sending it to the group to read.

 

Hugs Mary

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mary1kon

Friday, January 16, 2009 12:06 PM

The Ultimate Mitochondrial Cocktail - Part Two

 

 

 

 

 

 

 

 

 

 

Books Contact IMVA

 

 

 

 

 

 

The Ultimate Mitochondrial CocktailMagnesium Bicarbonate – Part Two

 

At the end of part one it was stated that: A person gets much more control over both bicarbonate and magnesium physiology when magnesium is taken in its chloride form and the bicarbonate is taken as sodium bicarbonate. Natural Allopathic medicines like these are easily combined and incorporated by the body because human physiology has been doing that for millions of years, combining nutritional substances we eat. The substances in Natural Allopathic Medicine are safe to combine because the body needs each one of them for proper function.

In the case of magnesium chloride and sodium bicarbonate we are actually incorporating four primary nutritional elements, magnesium, chloride, sodium and bicarbonate. In our work with sodium thiosulfate and magnesium thiosulfate we see that thiosulfate can easily be added to the protocol affecting to the sulfur pathways in the body. We are dealing with basic physiology with all the above elements so it is important to get a good grasp of the body’s needs and uses for these substances.

Whether or not to use combination therapy is no longer the question. Physicians are asking which combinations to use for which risk factors but in large they have not come to the conclusion that combination therapy is a disaster waiting to happen if one uses pharmaceutical drugs. Magnesium bicarbonate is the most prime combination with chloride and sodium being integrated for secondary effect. These substances are safe to use in high dosages whereas pharmaceuticals are dangerous even in ultra small doses.

The bicarbonate buffer system occurs in both intra- and extracellular fluids. It consists of carbonic acid (H2CO3) and sodium bicarbonate (NaHCO3). If a strong acid is present, it reacts with sodium bicarbonate to produce carbonic acid and sodium chloride, minimizing the increasing concentration of hydrogen ions. If a strong base is present, it reacts with carbonic acid, producing sodium bicarbonate and water, minimizing the alkaline shift.

Highly alkaline water with magnesium, bicarbonate,calcium and potassium increases pH significantly in the body.

Carbonic anhydrase (CA) is a ubiquitous metalloenzyme that catalyzes the reversible hydration/dehydration of carbon dioxide. Carbonic anhydrase enzyme is ever-present in body cells and constitutes up to ten percent of the soluble protein in most body cells. It is one of the fastest enzymes known: each carbonic anhydrase enzyme produces from ten thousand to one million acid groups (H+) per second. The acid (H+) produced by carbonic anhydrase enzyme is pumped by proton pump enzymes into cell organelles such as lysosomes, phagosomes, endosomes and ruffled membranes.

In red blood cells (rbcs), CA is the second most abundant protein to haemoglobin and plays a crucial role in CO2 transport. More specifically, rbc CA catalyzes the hydration of CO2 to HCO3– at the tissue site of production, and the dehydration of HCO –3 to CO2 at the respiratory surface, thereby facilitating the transport and excretion of CO2 from the body.1 In addition, rbc CA also facilitates the linkage of O2 and CO2 transport via the Bohr effect.2 Carbonic anhydrase speeds the reaction of carbon dioxide and water. This reaction produces carbonic acid, which quickly dissociates into bicarbonate and hydrogen ions.

Bicarbonate ion concentrations decrease the formation of acid by carbonic anhydrase enzyme (Le Chatelier's principle). In the presence of magnesium and bicarbonate ions, less acid is produced by carbonic anhydrase enzyme.3 But studies with partially purified carbonic anhydrase from spinach (Spinacia oleracea L.) chloroplasts show that the effect was the result of the chloride ion and not the magnesium ion. Enzyme activity was reduced 50% upon addition of 3 to 10 millimolar MgCl2 or KCl while all additions of MgSO4 between 0.3 and 10 millimolar were mildly stimulatory.4

Excess acid accumulation leads to oxygendeprivation and thus cell fermentation. Acidconditions lead to cell rot, another term for cancer.

This reaffirms my long standing belief that magnesium chloride is the absolute best form of magnesium for, among many reasons; the very important chloride ion is supplied. Chloride physiology is just one more basic that is being addressed. It is important because we see reduced acid through reduced carbonic anhydrase enzyme action. Chloride is required to produce a large quantity of gastric acid each day and is also needed to stimulate starch-digesting enzymes.

Using other magnesium salts is less advantageous because these have to be converted into chlorides in the body anyway. We may use magnesium as oxide or carbonate but then we need to produce additional hydrochloric acid to absorb them. Many aging individuals, especially with chronic diseases who desperately need more magnesium, cannot produce sufficient hydrochloric acid; and then they cannot absorb the oxide or carbonate.

Dr. David Brownstein importantly tells us, “Chloride and bromine compete for reabsorption in the kidneys. When there is a decreased amount of chloride in the body (which is common in low-salt diets), less bromine will be excreted from the kidneys resulting in elevated bromine levels. Increasing the amount of chloride in the diet will allow the kidneys to release more bromine into the urine for excretion." Bromide is a huge problem today and both Dr. Brownstein and I have written books on Iodine, which again bring in the salt question. Iodine gets its way into almost any medical protocol today and combines perfectly with magnesium chloride and sodium bicarbonate. (I recently received a note from Dr. Brownstein – “Loved your iodine book. Great piece of work! Can't wait for your next book.â€)

We are at a very interesting level of biology and physiology when we talk about bicarbonate, magnesium, and chloride ions. And even sodium in the sodium part of bicarbonate is absolutely essential to human health. As we mentioned in another chapter sodium bicarbonate as well as citrate and phosphate salts do not raise blood pressure to the same extent as do the corresponding amounts of sodium chloride. A study on mineral water containing sodium bicarbonate has confirmed the absence of any effect on blood pressure in elderly individuals.5

This is an updated chapter from my book.

Sodium itself is needed for many functions of the body. Its main function is in providing the balancing of fluids in the body. Sodium is necessary for life and a deficiency can result in often life threatening conditions such as dehydration, heart palpitations, and muscle cramping all of which can rapidly progress to more dangerous situations if left untreated. So sodium bicarbonate is a good way of getting the essential salt we need. Most of the salt that is consumed in the world is not any good anyway, it is salt with the minerals all stripped out and that goes for sea salt as well as mined processed salt. Salt is a very important subject. It is most effective in stabilizing irregular heartbeats and, contrary to the misconception that it causes high blood pressure, it is actually essential for the regulation of blood pressure - in conjunction with water. For more information read Dr. David Brownstein’s book SALT – Your Way to Health.

Sodium bicarbonate is known to decrease serum concentration of ionized magnesium ([Mg2+]) when sodium bicarbonate is added to neonatal serum in vitro. The addition of sodium bicarbonate causes a significant decrease in [Mg2+]. From this in vitro study we speculate that fast infusion of sodium bicarbonate in human neonates may potentially cause a clinically significant decrease in serum [Mg2+].6

Magnesium stabilizes ATP7, allowingDNA and RNA transcriptions and repairs.8

Where would the magnesium go but into the cells and bones where most magnesium reserves are found? Higher pH levels and the bicarbonate itself will help the magnesium leave the blood serum driving Mg2+ into the cells where again the bicarbonate will carry it from the cytoplasm into the mitochondria where, in cases of chronic disease, it is desperately needed. Thus magnesium and bicarbonate, when used together, would considerably increase the energy production in body cells.

Mg2+ is critical for all of the energeticsof the cells because it is absolutely requiredthat Mg2+ be bound by ATP the central high energy compound of the body. Dr. Boyd Haley

Magnesium bicarbonate decreases the production of acid from carbon dioxide in body cells. Magnesium and bicarbonate would at the same time increase energy in several ways. First, magnesium bicarbonate protects the natural organic and inorganic phosphate buffers in the cytoplasm of cells. Second, magnesium bicarbonate neutralizes the acid produced as a result of metabolic processes and ATP hydrolysis. This allows more ATP to be hydrolyzed; that is, more energy can be utilized.

Magnesium bicarbonate buffers the mitochondria in body cells from excess acid concentrations which improves mitochondrial function and allows more ATP to be produced. When more ATP can be hydrolyzed and more ATP can be produced, body cells have sufficient energy for optimum function.

ATP without Mg2+ bound cannot create the energynormally used by specific enzymes of the bodyto make protein, DNA, RNA, transport sodium orpotassium or calcium in and out of cells. ATP withoutenough Mg2+ is non-functional and leads to cell death. Dr. Boyd Haley

Dr Seeger and Dr Budwig in Germany have shown that cancer is mainly the result of a faulty energy metabolism in the powerhouses of the cells - the mitochondria. ATP and most of the enzymes involved in the production of energy require magnesium. A healthy cell has high magnesium and low calcium levels. The problem that comes with low magnesium (Mg) levels is the calcium builds up inside the cells while energy production decreases as the mitochondria gradually calcify. Thus taking magnesium chloride and sodium bicarbonate together is ideal for cellular environments turned acidic and calcified.

Magnesium ions constitute thephysiologically active magnesiumin the body; they are not attachedto other substances and are free to join inbiochemical body processes.9

There is no way one can address in this chapter all the possibilities and the medical power one can achieve when combining magnesium chloride with sodium bicarbonate. Whether one has heart or neurological disease, diabetes, cancer or a bad case of the flu taking these substances together offer doctors and patients safe and effective treatment.

So deep are the protective, buffering and neutralizing properties of bicarbonate that it is used even with radiation exposure to protect the kidneys and other tissues. In a world that is already overexposed to uranium oxide and mercury magnesium bicarbonate becomes even more important because mercury and uranium oxide directly attack the nuclear material and mitochondria of the cells.

The use of DU weaponry by the US, defying all internationaltreaties, will slowly annihilate all species on Earth includingthe human species, and yet this country continues to doso with full knowledge of its destructive potential.Leuren Moret

“Depleted (DU) uranium is highly toxic to humans, both chemically as a heavy metal and radiological as an alpha particle emitter, is very dangerous when taken internally,†writes Dr. Rosalie Bertell, Canadian Epidemiologist.10 A new study, conducted by biochemist Dr. Diane Stearns at Northern Arizona University confirms that, separate from any radiation risks, cells exposed to uranium will bond with the metal chemically.11

The kidneys are usually the first organs toshow chemical damage upon uraniumexposure, military manuals suggestdoses or infusions of sodium bicarbonate tohelp alkalinize the urine if this happens.This makes the uranyl ion less kidney-toxicand promotes excretion of the nontoxicuranium-carbonate complex.The oral administration of sodiumbicarbonate diminishes theseverity of the changes producedby uranium in the kidneys.12

Uranium and phosphate have a strong chemical affinity for each other and the DNA and Mitochondria are loaded with phosphate so uranium is a DNA and Mitochondria deep penetration bomb. The uranium is attacking on fundamental cellular levels while mercury offers a knock out punch by attacking the sulfur bonds besides being highly toxic to nerve cells. Nephrotoxicity of the kidneys with necrosis of proximal tubules has been seen to increase significantly with dual exposure to both uranium and mercury.13

Bicarbonate ions neutralizes carbonic acid formed in the body during metabolic processes. Several studies have shown that an increased intake of bicarbonate may help prevent muscle wasting and bone loss. Our diets are usually acid. Acids burn out our cells and causes accelerated aging. Bicarbonate is alkaline and provides the body with the extra alkalinity needed by the body to neutralize excess acidity.

The medical industrial complex has deliberately programmed generations of doctors to hold with the poor idea that using highly toxic and dangerous drugs is preferable to using vastly safer concentrated nutritional substances that make better medicines then any drug the pharmaceutical companies can fabricate. Magnesium chloride is used in emergency rooms and so is sodium bicarbonate to save lives everyday. Interesting that the medical intelligence has been lacking to combine the two and use their collective strength to even greater effect.

Emergency Room Medicines for Chronic and Acute Diseases.

Magnesium chloride, iodine and sodium bicarbonate actually replicate the biological action of prescription drugs at far less cost and with fewer side effects. They are like the primary colors on a master painter’s pallet; with the primaries one can make almost any color, or a doctor in his place could generate almost any medical effect safely and swiftly. There are other substances like these three but these are primary and impinge their benefits directly onto cell physiology in a very coordinated synergistic way.

Magnesium bicarbonate would clearly come out heads in the class of cerebral protective agents. Magnesium bicarbonate would offer significant cerebral protection with high preservation effect on neurological function following brain injury or in healing chronic impaired dysfunction like in Parkinson’s and Alzheimer’s diseases.

When the nervous system is injured, the brain produces self-protective molecules in an attempt to halt damage. Following injury, the death of nerve cells occurs over a prolonged period of many hours or days, which provides a “window†for therapeutic intervention. Magnesium chloride is the undisputed best first therapeutic agent to be injected for stroke and is being tested in ambulances in Los Angeles.

This chapter is opening up a new door for allopathic medicine because it combines two emergency room and intensive care medicines for everyday use. My new book that lays out my conceptual designs for the future of medicine is called Principles and Practices of Natural Allopathic Medicine. Magnesium chloride and Sodium Bicarbonate are non pharmaceutical, non toxic concentrated nutritional medicinal medicines. These are backbone medicines no clinic or home medical kit should be without.

Mark Sircus Ac., OMDDirector International Medical Veritas Association director

 

 

1 Perry, 1986; Perry and Laurent, 1990; Henry and Heming, 1998 http://www3.interscience.wiley.com/journal/119558225/abstract?CRETRY=1 & SRETRY=0#c1

 

2 Forster and Steen, 1968; Maren and Swenson, 1980

 

3 Bamberger and Avron 1975 Plant Physiol 56: 481-485

 

4 Regulation of Chloroplastic Carbonic Anhydrase. Effect of MagnesiumMichael A. Porter and Bernard GrodzinskiPlant Physiology, Vol. 72, No. 3 (Jul., 1983), pp. 604-605 (article consists of 2 pages) Published by: American Society of Plant Biologists

 

5 News vol 3, no 1, May 2001

 

6 Magnesium research 2004, vol. 17, no2, pp. 90-93

 

7 Mg2+ is critical for all of the energetics of the cells because it is absolutely required that Mg2+ be bound (chelated) by ATP (adenosine triphosphate), the central high energy compound of the body. ATP without Mg2+ bound cannot create the energy normally used by specific enzymes of the body to make protein, DNA, RNA, transport sodium or potassium or calcium in and out of cells, nor to phosphorylate proteins in response to hormone signals, etc. In fact, ATP without enough Mg2+ is non-functional and leads to cell death. Bound Mg2+ holds the triphosphate in the correct stereochemical position so that it can interact with ATP using enzymes and the Mg2+ also polarizes the phosphate backbone so that the 'backside of the phosphorous' is more positive and susceptible to attack by nucleophilic agents such as hydroxide ion or other negatively charged compounds. Bottom line, Mg2+ at critical concentrations is essential to life,†says Dr. Boyd Haley who asserts strongly that, “All detoxification mechanisms have as the bases of the energy required to remove a toxicant the need for Mg-ATP to drive the process. There is nothing done in the body that does not use energy and without Mg2+ this energy can neither be made nor used.†Detoxification of carcinogenic chemical poisons is essential for people want to avoid the ravages of cancer. The importance of magnesium in cancer prevention should not be underestimated.

 

8 Magnesium has a central regulatory role in the cell cycle including that of affecting transphorylation and DNA synthesis, has been proposed as the controller of cell growth, rather than calcium. It is postulated that Mg++ controls the timing of spindle and chromosome cycles by changes in intracellular concentration during the cell cycle. Magnesium levels fall as cells enlarge until they reach a level that allows for spindle formation. Mg influx then causes spindle breakdown and cell division.

 

9 Altura BM, Altura BT, “Role of magnesium in patho-physiological process and the clinical utility of magnesium íon selective electrodes.†Scand J Clin Lab Invest Suppl, vol. 224, pp.211-234, 1996

 

10 http://cndyorks.gn.apc.org/news/articles/du/drrb.htm

 

11 A radioisotope of an element will bind best to the same substrates which a non-radioactive isotope of the same element will bind. Dr. Stearns has established that when cells are exposed to uranium, the uranium binds to DNA and the cells acquire mutations, triggering a whole slew of protein replication errors, some of which can lead to various cancers. Stearns' research, published in the journals Mutagenesis and Molecular Carcinogenesis, confirms what many have suspected for some time - that uranium can damage DNA as a heavy metal, independent of its radioactive properties. The biochemical reaction of heavy metals can cause genetic mutations, which in turn can curtail cell growth and cause cancer. Heavy metals that are also radioactive amplify this effect and can cause distortions in shape and thus function even of red blood cells.

 

12 A study of the acidosis, blood urea, and plasma chlorides in uranium nephritis in the dog, and the protective action of sodium bicarbonate. The Journal of Experimental Medicine, Vol 25, 693-719, Copyright, 1917, by The Rockefeller Institute for Medical Research New York http://www.jem.org/cgi/content/abstract/25/5/693

 

13 Biol Trace Elem Res. 2001 Winter;84(1-3):139-54. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=11817685 & dopt=Abstract

 

Legal Notice: The Author specifically invokes the First Amendment rights of freedom of speech and of the press without prejudice. The information written is published for informational purposes only under the rights guaranteed by the First Amendment of the Constitution for the United States of America, and should not in any way be used as a substitute for the advice of a physician or other licensed health care practitioner. The statements contained herein have not been evaluated by the FDA. The products discussed herein are not intended to diagnose, cure, prevent or treat any disease. Images, text and logic are copyright protected. ALL rights are explicitly reserved without prejudice, and no part of this essay may be reproduced except by written consent. ©2008 by Mark Sircus

 

 

 

 

 

 

 

 

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cfrench180

Thursday, January 15, 2009 8:06 PM

The Ultimate Mitochondrial Cocktail - Part Two

 

 

 

 

 

 

 

 

 

 

Books Contact IMVA

 

 

 

 

 

 

The Ultimate Mitochondrial CocktailMagnesium Bicarbonate – Part Two

 

At the end of part one it was stated that: A person gets much more control over both bicarbonate and magnesium physiology when magnesium is taken in its chloride form and the bicarbonate is taken as sodium bicarbonate. Natural Allopathic medicines like these are easily combined and incorporated by the body because human physiology has been doing that for millions of years, combining nutritional substances we eat. The substances in Natural Allopathic Medicine are safe to combine because the body needs each one of them for proper function.

In the case of magnesium chloride and sodium bicarbonate we are actually incorporating four primary nutritional elements, magnesium, chloride, sodium and bicarbonate. In our work with sodium thiosulfate and magnesium thiosulfate we see that thiosulfate can easily be added to the protocol affecting to the sulfur pathways in the body. We are dealing with basic physiology with all the above elements so it is important to get a good grasp of the body’s needs and uses for these substances.

Whether or not to use combination therapy is no longer the question. Physicians are asking which combinations to use for which risk factors but in large they have not come to the conclusion that combination therapy is a disaster waiting to happen if one uses pharmaceutical drugs. Magnesium bicarbonate is the most prime combination with chloride and sodium being integrated for secondary effect. These substances are safe to use in high dosages whereas pharmaceuticals are dangerous even in ultra small doses.

The bicarbonate buffer system occurs in both intra- and extracellular fluids. It consists of carbonic acid (H2CO3) and sodium bicarbonate (NaHCO3). If a strong acid is present, it reacts with sodium bicarbonate to produce carbonic acid and sodium chloride, minimizing the increasing concentration of hydrogen ions. If a strong base is present, it reacts with carbonic acid, producing sodium bicarbonate and water, minimizing the alkaline shift.

Highly alkaline water with magnesium, bicarbonate,calcium and potassium increases pH significantly in the body.

Carbonic anhydrase (CA) is a ubiquitous metalloenzyme that catalyzes the reversible hydration/dehydration of carbon dioxide. Carbonic anhydrase enzyme is ever-present in body cells and constitutes up to ten percent of the soluble protein in most body cells. It is one of the fastest enzymes known: each carbonic anhydrase enzyme produces from ten thousand to one million acid groups (H+) per second. The acid (H+) produced by carbonic anhydrase enzyme is pumped by proton pump enzymes into cell organelles such as lysosomes, phagosomes, endosomes and ruffled membranes.

In red blood cells (rbcs), CA is the second most abundant protein to haemoglobin and plays a crucial role in CO2 transport. More specifically, rbc CA catalyzes the hydration of CO2 to HCO3– at the tissue site of production, and the dehydration of HCO –3 to CO2 at the respiratory surface, thereby facilitating the transport and excretion of CO2 from the body.1 In addition, rbc CA also facilitates the linkage of O2 and CO2 transport via the Bohr effect.2 Carbonic anhydrase speeds the reaction of carbon dioxide and water. This reaction produces carbonic acid, which quickly dissociates into bicarbonate and hydrogen ions.

Bicarbonate ion concentrations decrease the formation of acid by carbonic anhydrase enzyme (Le Chatelier's principle). In the presence of magnesium and bicarbonate ions, less acid is produced by carbonic anhydrase enzyme.3 But studies with partially purified carbonic anhydrase from spinach (Spinacia oleracea L.) chloroplasts show that the effect was the result of the chloride ion and not the magnesium ion. Enzyme activity was reduced 50% upon addition of 3 to 10 millimolar MgCl2 or KCl while all additions of MgSO4 between 0.3 and 10 millimolar were mildly stimulatory.4

Excess acid accumulation leads to oxygendeprivation and thus cell fermentation. Acidconditions lead to cell rot, another term for cancer.

This reaffirms my long standing belief that magnesium chloride is the absolute best form of magnesium for, among many reasons; the very important chloride ion is supplied. Chloride physiology is just one more basic that is being addressed. It is important because we see reduced acid through reduced carbonic anhydrase enzyme action. Chloride is required to produce a large quantity of gastric acid each day and is also needed to stimulate starch-digesting enzymes.

Using other magnesium salts is less advantageous because these have to be converted into chlorides in the body anyway. We may use magnesium as oxide or carbonate but then we need to produce additional hydrochloric acid to absorb them. Many aging individuals, especially with chronic diseases who desperately need more magnesium, cannot produce sufficient hydrochloric acid; and then they cannot absorb the oxide or carbonate.

Dr. David Brownstein importantly tells us, “Chloride and bromine compete for reabsorption in the kidneys. When there is a decreased amount of chloride in the body (which is common in low-salt diets), less bromine will be excreted from the kidneys resulting in elevated bromine levels. Increasing the amount of chloride in the diet will allow the kidneys to release more bromine into the urine for excretion." Bromide is a huge problem today and both Dr. Brownstein and I have written books on Iodine, which again bring in the salt question. Iodine gets its way into almost any medical protocol today and combines perfectly with magnesium chloride and sodium bicarbonate. (I recently received a note from Dr. Brownstein – “Loved your iodine book. Great piece of work! Can't wait for your next book.â€)

We are at a very interesting level of biology and physiology when we talk about bicarbonate, magnesium, and chloride ions. And even sodium in the sodium part of bicarbonate is absolutely essential to human health. As we mentioned in another chapter sodium bicarbonate as well as citrate and phosphate salts do not raise blood pressure to the same extent as do the corresponding amounts of sodium chloride. A study on mineral water containing sodium bicarbonate has confirmed the absence of any effect on blood pressure in elderly individuals.5

This is an updated chapter from my book.

Sodium itself is needed for many functions of the body. Its main function is in providing the balancing of fluids in the body. Sodium is necessary for life and a deficiency can result in often life threatening conditions such as dehydration, heart palpitations, and muscle cramping all of which can rapidly progress to more dangerous situations if left untreated. So sodium bicarbonate is a good way of getting the essential salt we need. Most of the salt that is consumed in the world is not any good anyway, it is salt with the minerals all stripped out and that goes for sea salt as well as mined processed salt. Salt is a very important subject. It is most effective in stabilizing irregular heartbeats and, contrary to the misconception that it causes high blood pressure, it is actually essential for the regulation of blood pressure - in conjunction with water. For more information read Dr. David Brownstein’s book SALT – Your Way to Health.

Sodium bicarbonate is known to decrease serum concentration of ionized magnesium ([Mg2+]) when sodium bicarbonate is added to neonatal serum in vitro. The addition of sodium bicarbonate causes a significant decrease in [Mg2+]. From this in vitro study we speculate that fast infusion of sodium bicarbonate in human neonates may potentially cause a clinically significant decrease in serum [Mg2+].6

Magnesium stabilizes ATP7, allowingDNA and RNA transcriptions and repairs.8

Where would the magnesium go but into the cells and bones where most magnesium reserves are found? Higher pH levels and the bicarbonate itself will help the magnesium leave the blood serum driving Mg2+ into the cells where again the bicarbonate will carry it from the cytoplasm into the mitochondria where, in cases of chronic disease, it is desperately needed. Thus magnesium and bicarbonate, when used together, would considerably increase the energy production in body cells.

Mg2+ is critical for all of the energeticsof the cells because it is absolutely requiredthat Mg2+ be bound by ATP the central high energy compound of the body. Dr. Boyd Haley

Magnesium bicarbonate decreases the production of acid from carbon dioxide in body cells. Magnesium and bicarbonate would at the same time increase energy in several ways. First, magnesium bicarbonate protects the natural organic and inorganic phosphate buffers in the cytoplasm of cells. Second, magnesium bicarbonate neutralizes the acid produced as a result of metabolic processes and ATP hydrolysis. This allows more ATP to be hydrolyzed; that is, more energy can be utilized.

Magnesium bicarbonate buffers the mitochondria in body cells from excess acid concentrations which improves mitochondrial function and allows more ATP to be produced. When more ATP can be hydrolyzed and more ATP can be produced, body cells have sufficient energy for optimum function.

ATP without Mg2+ bound cannot create the energynormally used by specific enzymes of the bodyto make protein, DNA, RNA, transport sodium orpotassium or calcium in and out of cells. ATP withoutenough Mg2+ is non-functional and leads to cell death. Dr. Boyd Haley

Dr Seeger and Dr Budwig in Germany have shown that cancer is mainly the result of a faulty energy metabolism in the powerhouses of the cells - the mitochondria. ATP and most of the enzymes involved in the production of energy require magnesium. A healthy cell has high magnesium and low calcium levels. The problem that comes with low magnesium (Mg) levels is the calcium builds up inside the cells while energy production decreases as the mitochondria gradually calcify. Thus taking magnesium chloride and sodium bicarbonate together is ideal for cellular environments turned acidic and calcified.

Magnesium ions constitute thephysiologically active magnesiumin the body; they are not attachedto other substances and are free to join inbiochemical body processes.9

There is no way one can address in this chapter all the possibilities and the medical power one can achieve when combining magnesium chloride with sodium bicarbonate. Whether one has heart or neurological disease, diabetes, cancer or a bad case of the flu taking these substances together offer doctors and patients safe and effective treatment.

So deep are the protective, buffering and neutralizing properties of bicarbonate that it is used even with radiation exposure to protect the kidneys and other tissues. In a world that is already overexposed to uranium oxide and mercury magnesium bicarbonate becomes even more important because mercury and uranium oxide directly attack the nuclear material and mitochondria of the cells.

The use of DU weaponry by the US, defying all internationaltreaties, will slowly annihilate all species on Earth includingthe human species, and yet this country continues to doso with full knowledge of its destructive potential.Leuren Moret

“Depleted (DU) uranium is highly toxic to humans, both chemically as a heavy metal and radiological as an alpha particle emitter, is very dangerous when taken internally,†writes Dr. Rosalie Bertell, Canadian Epidemiologist.10 A new study, conducted by biochemist Dr. Diane Stearns at Northern Arizona University confirms that, separate from any radiation risks, cells exposed to uranium will bond with the metal chemically.11

The kidneys are usually the first organs toshow chemical damage upon uraniumexposure, military manuals suggestdoses or infusions of sodium bicarbonate tohelp alkalinize the urine if this happens.This makes the uranyl ion less kidney-toxicand promotes excretion of the nontoxicuranium-carbonate complex.The oral administration of sodiumbicarbonate diminishes theseverity of the changes producedby uranium in the kidneys.12

Uranium and phosphate have a strong chemical affinity for each other and the DNA and Mitochondria are loaded with phosphate so uranium is a DNA and Mitochondria deep penetration bomb. The uranium is attacking on fundamental cellular levels while mercury offers a knock out punch by attacking the sulfur bonds besides being highly toxic to nerve cells. Nephrotoxicity of the kidneys with necrosis of proximal tubules has been seen to increase significantly with dual exposure to both uranium and mercury.13

Bicarbonate ions neutralizes carbonic acid formed in the body during metabolic processes. Several studies have shown that an increased intake of bicarbonate may help prevent muscle wasting and bone loss. Our diets are usually acid. Acids burn out our cells and causes accelerated aging. Bicarbonate is alkaline and provides the body with the extra alkalinity needed by the body to neutralize excess acidity.

The medical industrial complex has deliberately programmed generations of doctors to hold with the poor idea that using highly toxic and dangerous drugs is preferable to using vastly safer concentrated nutritional substances that make better medicines then any drug the pharmaceutical companies can fabricate. Magnesium chloride is used in emergency rooms and so is sodium bicarbonate to save lives everyday. Interesting that the medical intelligence has been lacking to combine the two and use their collective strength to even greater effect.

Emergency Room Medicines for Chronic and Acute Diseases.

Magnesium chloride, iodine and sodium bicarbonate actually replicate the biological action of prescription drugs at far less cost and with fewer side effects. They are like the primary colors on a master painter’s pallet; with the primaries one can make almost any color, or a doctor in his place could generate almost any medical effect safely and swiftly. There are other substances like these three but these are primary and impinge their benefits directly onto cell physiology in a very coordinated synergistic way.

Magnesium bicarbonate would clearly come out heads in the class of cerebral protective agents. Magnesium bicarbonate would offer significant cerebral protection with high preservation effect on neurological function following brain injury or in healing chronic impaired dysfunction like in Parkinson’s and Alzheimer’s diseases.

When the nervous system is injured, the brain produces self-protective molecules in an attempt to halt damage. Following injury, the death of nerve cells occurs over a prolonged period of many hours or days, which provides a “window†for therapeutic intervention. Magnesium chloride is the undisputed best first therapeutic agent to be injected for stroke and is being tested in ambulances in Los Angeles.

This chapter is opening up a new door for allopathic medicine because it combines two emergency room and intensive care medicines for everyday use. My new book that lays out my conceptual designs for the future of medicine is called Principles and Practices of Natural Allopathic Medicine. Magnesium chloride and Sodium Bicarbonate are non pharmaceutical, non toxic concentrated nutritional medicinal medicines. These are backbone medicines no clinic or home medical kit should be without.

Mark Sircus Ac., OMDDirector International Medical Veritas Association director

 

 

1 Perry, 1986; Perry and Laurent, 1990; Henry and Heming, 1998 http://www3.interscience.wiley.com/journal/119558225/abstract?CRETRY=1 & SRETRY=0#c1

 

2 Forster and Steen, 1968; Maren and Swenson, 1980

 

3 Bamberger and Avron 1975 Plant Physiol 56: 481-485

 

4 Regulation of Chloroplastic Carbonic Anhydrase. Effect of MagnesiumMichael A. Porter and Bernard GrodzinskiPlant Physiology, Vol. 72, No. 3 (Jul., 1983), pp. 604-605 (article consists of 2 pages) Published by: American Society of Plant Biologists

 

5 News vol 3, no 1, May 2001

 

6 Magnesium research 2004, vol. 17, no2, pp. 90-93

 

7 Mg2+ is critical for all of the energetics of the cells because it is absolutely required that Mg2+ be bound (chelated) by ATP (adenosine triphosphate), the central high energy compound of the body. ATP without Mg2+ bound cannot create the energy normally used by specific enzymes of the body to make protein, DNA, RNA, transport sodium or potassium or calcium in and out of cells, nor to phosphorylate proteins in response to hormone signals, etc. In fact, ATP without enough Mg2+ is non-functional and leads to cell death. Bound Mg2+ holds the triphosphate in the correct stereochemical position so that it can interact with ATP using enzymes and the Mg2+ also polarizes the phosphate backbone so that the 'backside of the phosphorous' is more positive and susceptible to attack by nucleophilic agents such as hydroxide ion or other negatively charged compounds. Bottom line, Mg2+ at critical concentrations is essential to life,†says Dr. Boyd Haley who asserts strongly that, “All detoxification mechanisms have as the bases of the energy required to remove a toxicant the need for Mg-ATP to drive the process. There is nothing done in the body that does not use energy and without Mg2+ this energy can neither be made nor used.†Detoxification of carcinogenic chemical poisons is essential for people want to avoid the ravages of cancer. The importance of magnesium in cancer prevention should not be underestimated.

 

8 Magnesium has a central regulatory role in the cell cycle including that of affecting transphorylation and DNA synthesis, has been proposed as the controller of cell growth, rather than calcium. It is postulated that Mg++ controls the timing of spindle and chromosome cycles by changes in intracellular concentration during the cell cycle. Magnesium levels fall as cells enlarge until they reach a level that allows for spindle formation. Mg influx then causes spindle breakdown and cell division.

 

9 Altura BM, Altura BT, “Role of magnesium in patho-physiological process and the clinical utility of magnesium íon selective electrodes.†Scand J Clin Lab Invest Suppl, vol. 224, pp.211-234, 1996

 

10 http://cndyorks.gn.apc.org/news/articles/du/drrb.htm

 

11 A radioisotope of an element will bind best to the same substrates which a non-radioactive isotope of the same element will bind. Dr. Stearns has established that when cells are exposed to uranium, the uranium binds to DNA and the cells acquire mutations, triggering a whole slew of protein replication errors, some of which can lead to various cancers. Stearns' research, published in the journals Mutagenesis and Molecular Carcinogenesis, confirms what many have suspected for some time - that uranium can damage DNA as a heavy metal, independent of its radioactive properties. The biochemical reaction of heavy metals can cause genetic mutations, which in turn can curtail cell growth and cause cancer. Heavy metals that are also radioactive amplify this effect and can cause distortions in shape and thus function even of red blood cells.

 

12 A study of the acidosis, blood urea, and plasma chlorides in uranium nephritis in the dog, and the protective action of sodium bicarbonate. The Journal of Experimental Medicine, Vol 25, 693-719, Copyright, 1917, by The Rockefeller Institute for Medical Research New York http://www.jem.org/cgi/content/abstract/25/5/693

 

13 Biol Trace Elem Res. 2001 Winter;84(1-3):139-54. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=11817685 & dopt=Abstract

 

Legal Notice: The Author specifically invokes the First Amendment rights of freedom of speech and of the press without prejudice. The information written is published for informational purposes only under the rights guaranteed by the First Amendment of the Constitution for the United States of America, and should not in any way be used as a substitute for the advice of a physician or other licensed health care practitioner. The statements contained herein have not been evaluated by the FDA. The products discussed herein are not intended to diagnose, cure, prevent or treat any disease. Images, text and logic are copyright protected. ALL rights are explicitly reserved without prejudice, and no part of this essay may be reproduced except by written consent. ©2008 by Mark Sircus

 

 

 

 

 

 

 

 

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