FW: [iodine] New Study: Pathways in Antiprolif. Effect of Iodine in Breast C

[Guest guest]

Duke,

 

This is wonderful news!

 

And yes, the mold will make you very ill. I am glad that you have made

such a big difference already. Are you sure you are getting to the

" root " of the mold problem?

 

Anyway, please keep us posted as to your improvement.

 

You have made my day!

 

Hugs,

 

 

oleander soup , Duke Stone <dukesdeals wrote:

>

> I think this is getting right to the point. Not sure that a sick

person really needs all the science but it of course doesn't hurt.

>

> It appears that I am back where I was two months ago with lots of

energy and ambition and may have found the cause of all my distress. The

ninety year old house is full of mold and the hydroxyl producing light

bulb and the use of six or eight different methods of cleaning up the

air and junk that has accumulated is making a big differents. Yesterday

I discovered how infested the under side of the surface of the coils in

the Central air conditioner were and spent about six hour with various

organic cleaners plus direct ozone to the area and wow what a

difference.

>

> Plus upping my Lugal's to 40 drops a day and using Betadine directly

on the tumor. Which has begun to look very different and last night I

was actually able to eat -- not much but it did go down.

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Duke Stone ----- Dallas, Texas

> info

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> --- On Mon, 10/27/08, Nonie nmsammy wrote:

>

> Nonie nmsammy

> FW: [iodine] New Study: Pathways in

Antiprolif. Effect of Iodine in Breast Cancer Cells

> oleander soup

> Monday, October 27, 2008, 2:23 AM

More food for thought. This was sent to the Iodine group. I have

permission to cross post.

>

> Nonie

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> Cited below is the abstract for the new Aceves Group study,

" Signalling Pathways Involved in the Antiproliferative effect of

Molecular Iodine in Normal and Tumoral Breast Cells: Evidence that

6-Iodolactone Mediates Apoptotic Cells. "

>

> SUMMARY: Iodine exerts its cancer-killing capability in breast

cancer cells by binding with high concentrations of polyunsaturated fats

found in breast tumors.

>

> Sally

> Breast Cancer Choices

> www.breastcancercho ices.org

>

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>

> 1: Endocr Relat Cancer. 2008 Sep 30. [Epub ahead of print] Links

>

>

> Signalling pathways involved in the antiproliferative effect of

molecular iodine in normal and tumoral breast cells: evidence that

6-iodolactone mediates apoptotic effects.

> Arroyo-Helguera O, Rojas E, Delgado G, Aceves C.

> O Arroyo-Helguera, Instituto de Neurobiologia, UNAM-Juriquilla,

Universidad Nacional Autonoma de Mexico, Juriquilla, Mexico.

> Previous reports have documented the antiproliferative properties of

molecular iodine (I2) and the arachidonic acid (AA) derivative

6-iodolactone (6-IL) in both thyroid and mammary gland. In this study,

we characterized the cellular pathways activated by these molecules and

their effects on cell cycle arrest and apoptosis in normal (MCF-12F) and

cancerous (MCF-7) breast cells. Low to moderate concentrations of I2

(10-20 muM) cause G1 and G2/M phase arrest in MCF-12F, and

caspase-dependent apoptosis in MCF-7 cells. In normal cells, only high

doses of I2 (40 muM) induced apoptosis, and this effect was mediated by

poly (ADP-ribose) polymerase-1 (PARP-1) and the apoptosis-induced factor

(AIF), suggesting an oxidative influence of iodine at high

concentrations. Our data indicate that both I2 and 6-IL trigger the same

intracellular pathways and suggest that the antineoplasic effect of I2

in mammary cancer involves the intracellular formation of 6-IL. Mammary

> cancer cells are known to contain high concentrations of arachidonic

acid, which might explain why I2 exerts apoptotic effects at lower

concentrations only in tumoral cells.

> PMID: 18827038 [PubMed - as supplied by publisher]

>