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Quercetin reduces blood pressure in adults with hypertension

 

 

Quercetin, an antioxidant found many foods including onions, berries and apples,

is

associated with a reduced risk of heart disease and stroke. Supplementation with

quercetin has been shown to reduce hypertension in animal models, but until now

has

never been tested in hypertensive humans.

 

 

Researchers at the University of Utah, in collaboration with USANA Health

Sciences,

conducted a randomized, double-blind, placebo-controlled, crossover study to

test the

effectiveness of quercetin supplementation in lowering unhealthy blood pressure

levels.

The subjects were divided into two groups: prehypertensives (120-139 mm Hg

systolic/

80-89 mm Hg diastolic) or stage 1 hypertensives (140-159 mm Hg systolic/90-99 mm

Hg

diastolic). The participants were given either 730 mg quercetin/day or placebo

for 28

days.

 

Blood pressure remained unchanged in prehypertensives after supplementation with

quercetin. In contrast, stage 1 hypertensive subjects showed significant

reductions in both

systolic (-7 mm Hg) and diastolic (-2 mm Hg) blood pressure after quercetin

supplementation. This is the first published study to show that quercetin

supplementation

can reduce blood pressure in hypertensive adult humans. Additionally, it is

important to

note that quercetin supplementation did not influence the blood pressure of non-

hypertensive individuals.

 

J. Nutr. 137:2405-2411, November 2007

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