Estrogen and Melatonin Metabolites Among Women Residing Near Radio and Television Broadcasting Transmitters

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Biomonitoring of Estrogen and Melatonin Metabolites Among Women ResidingNear Radio and Television Broadcasting Transmitters.Journal of Occupational & Environmental Medicine. 49(10):1149- 1156,October 2007.Clark, Maggie L et al.Abstract:Objectives: Metabolites of estrogen (estrone-3-glucuron ide [E1G]) andmelatonin (6-hydroxymelatonin sulfate [6-OHMS]) were characterized amongwomen living in a community with increased radiofrequency (RF) exposurefrom radio and television transmitters.Methods: RF spot measurements, and personal 60-Hz magnetic field andresidential parameters were collected. Overnight urine samples wereassayed for E1G and 6-OHMS excretion.Results: Among premenopausal women, there were no associations between RFor 60-Hz nonionizing radiation and E1G or 6-OHMS excretion. Amongpostmenopausal women, increased residential RF exposures,

transmitterproximity and visibility, and temporally stable 60-Hz exposures weresignificantly associated with increased E1G excretion. This associationwas strongest among postmenopausal women with low overnight 6-OHMS levels.Conclusions: RF and temporally stable 60-Hz exposures were associated withincreased E1G excretion among postmenopausal women. Women with reducednocturnal 6-OHMS excretion may represent a sensitive subgroup.©2007The American College of Occupational and Environmental Medicine http://tinyurl. com/322yq7