Cardiac Insufficiency Hypothesis - new articles at M.E. Society of America

[Guest guest]

This site has just been updated.

From what I have heard and seen, these would be helpful and informative to

read, in my opinion anyways.

There are also several more articles at this url which many of you might

find helpful.

blessings

Shan

 

Cardiac Insufficiency Hypothesis

http://www.cfids-cab.org/MESA/Lerner.html

 

There is new research from a New Jersey team, authored by Doctors Arnold

Peckerman, Benjamin Natelson et al., which found left-ventricular dysfunction

following exertion and orthostatic stress in patients with myalgic

encephalomyelitis/chronic fatigue syndrome.

The WedMD article and the press release are available at the link below.

 

Dr. A. Martin Lerner holds U.S. patents for the diagnosis of ME/CFS in the

chronic mononucleosis subset of this disease using 24-hour Holter monitoring.

He argues that a prominent subset of the disease is a prolonged, chronic

mononucleosis following infection with herpesviruses Epstein Barr (EBV), Human

Cytomegalovirus (HCMV), or both, and/or possibly Human Herpes Virus 6 (HHV-6).

Viral infection persists in the heart, causing left-ventricular dysfunction,

producing exercise intolerance. Exercise, in turn, worsens the cardiac

dysfunction. He has also postulated that the disease is an early dilated

cardiomyopathy that in later stages might result in progressive, end-stage

dilated

cardiomyopathy, a type of heart failure. Dilated cardiomyopathy is sometimes

viewed

as " idiopathic, " or " Idiopathic Dilated Cardiomyopathy " (IDC). In an

editorial response titled " Microbial Persistence and Idiopathic Dilated

Cardiomyopathy, " Dr. Lerner has postulated that herpesviruses may be the

etiological link.

 

More recently, physicist, physician, long-time ME/CFS researcher and

clinician, and heart transplant recipient Dr. Paul Cheney, M.D., Ph.D., has

offered an

alternative theory that a subset of ME/CFS patients suffer from a diastolic

cardiomyopathy, a problem with ventricular filling. A video cassette of a

recent seminar Dr. Cheney presented on diastolic cardiomyopathy in ME/CFS can be

obtained here. (Allow two months for delivery.) A discussion of Dr. Cheney's

views is available below in an interview by Carol Sieverling.

 

Some of Dr. Lerner's significant articles, as well as his patent issued in

2002, are linked below in Portable Document File (PDF) format. These files

require an Adobe Acrobat Reader. Most computers come with this program

preloaded.

If not, a free Acrobat Reader can be downloaded here.

http://www.adobe.com/products/acrobat/readstep2.html

http://www.adobe.com/products/acrobat/readstep2_allversions.html

 

 

New Research on Cardiac Insufficiency

 

Information on the study " Left Ventricular Function in Chronic Fatigue

Syndrome (CFS): Data From Nuclear Ventriculography Studies of Response to

Exercise

and Postural Stress, "

http://www.cfids-cab.org/MESA/cardiac.html

by Arnold Peckerman, Benjamin Natelson et al. [This study found that the

heart failed to pump enough blood following exertion and upright posture in the

CFS patients that were studied.]

 

Peckerman A, LaManca JJ, Dahl KA, Chemitiganti R, Qureishi B, Natelson BH.

" Abnormal impedance cardiography predicts symptom severity in chronic fatigue

syndrome. "

http://www.cfids-cab.org/MESA/cardiac-1.html

Am J Med Sci. 2003 Aug;326(2):55-60.

 

Arnold Peckerman, PhD, John J. LaManca, PhD, Bushra Qureishi, MD, Kristina A.

Dahl, MD, Roseli Golfetti, PhD, Yoshiharu Yamamoto, PhD and Benjamin H.

Natelson, " Baroreceptor Reflex and Integrative Stress Responses in Chronic

Fatigue

Syndrome. "

http://www.cfids-cab.org/MESA/cardiac-2.html

Psychosomatic Medicine 65:889-895 (2003)

 

 

Dr. Sarah Myhill, " CFS is Heart Failure Secondary to Mitochondrial

Malfunction. " Pamphlet. [PDF Format]

http://www.cfids-cab.org/MESA/DrMyhill-373.pdf

 

 

Carol Sieverling, " The Heart of the Matter: CFS & Cardiac Issues. " Dr. Paul

Cheney's theoretical insights on ME/CFS and heart failure. Pamphlet. [PDF

Format] http://www.cfids-cab.org/MESA/Cheney.pdf

 

 

U.S. Patent issued to Dr. Lerner on June 4, 2002, for a " Method for

Diagnosing and alleviating the symptoms of chronic fatigue syndrome. " [PDF

Format]

http://www.cfidscab.org/MESA/Lerner%20Patent%20Oct%202001.pdf

 

Hawthorn Extract

 

Pittler MH, Schmidt K, Ernst E., Hawthorn extract for treating chronic heart

failure: meta-analysis of randomized trials.

http://www.cfids-cab.org/MESA/Hawthorn.pdf

Am J Med. 2003 Jun 1;114(8):665-74. [PDF Format]

 

[Note: The M.E. Society of America does not recommend treatments for ME/CFS

or for any other disease. We are providing this article on Hawthorn for heart

failure for informational purposes only. Patients should consult with their

licensed healthcare professional about their own healthcare needs.]

 

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M.E. Society of America

Page last updated: April 10, 2006