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GMW: Honest Science Under Siege

" GM WATCH " <info

Fri, 22 Jul 2005 10:13:37 +0100

 

 

 

 

GM WATCH daily

http://www.gmwatch.org

------

" We have merely scratched the surface here. The corruption of the

scientific enterprise has proceeded very far. In some areas of scientific

endeavor, there are almost no independent researchers left because

nearly every scientist in the field is funded by corporations with an

axe to

grind. "

------

Honest Science Under Siege

 

Conflicts of interest, 'seeding results' and a broken monitoring system

erode the public's trust

 

Tim Montague (internews)

 

Toxic Emissions and Developmental Diseases

 

An ill wind is gusting through the halls of science these days: faked

research, suppression of unwelcome results, corruption of science

advisory panels, university research falling under the influence of

corporate

sponsors, and many other conflicts of interest.

 

It's as if science were under siege.

 

For at least the last 30 years science has strongly supported the

positions taken by environmental and public health advocates. The

proponents

of 'business as usual' have claimed that chemical and nuclear

technologies have created only minor problems or no problems

whatsoever -- but

time after time science has shown otherwise.

 

They said global warming was a " chicken little " fantasy. They said the

Earth's ozone shield couldn't possible be harmed. They argued that

asbestos was benign. They said lead in paint and gasoline was entirely

safe. They said harm from hormone-disrupting chemicals was imaginary.

They

said a little radioactivity might actually improve your health. They

said human health was constantly and consistently improving -- until

scientific study revealed increases in birth defects, asthma, diabetes,

attention deficits, nervous system disorders, diseases of the

reproductive

system, immune system disorders, cancer in children, and on and on. In

each of these cases science showed that the advocates of 'business as

usual' were simply wrong.

 

Science cannot solve all our problems or tell us everything we need to

know, but it remains a powerful tool for reaching agreement about the

nature of reality (at least for those parts of reality amenable to

scientific inquiry). For the past 30 years, science has shown us

unmistakably that we are destroying the natural systems (and bodily

defenses) that

we ourselves depend upon, so 'business as usual' is a dead end.

 

Perhaps this is why science itself is now under systematic attack by

corporate interests. Whatever the underlying reasons, it seems clear that

industry has lined up to discredit science, control the research

agenda, take over the apparatus for scholarly publication and otherwise

undermine the scientific and democratic pursuit of knowledge in the

public

interest. Perhaps they see it as their only hope of defending themselves

against the overwhelming scientific evidence that -- if accepted by the

public -- would end 'business as usual' and set us on a new

precautionary path.

 

The Los Angeles Times reported July 11 that allegations of faked

scientific findings increased 50 percent between 2003 and 2004.[1] But

the

Times also noted that the federal Office of Research Integrity cannot

keep up with the rising tide of scientific fakery because it's budget is

far too small. The office received 274 allegations of scientific fakery

in 2004, but was able to complete only 23 investigations.

 

Corporate suppression of data is now so routine that no one raises an

eyebrow. In the wake of an EPA advisory panel classifying the Teflon

chemical C8 (ammonium perfluorooctanoate, or PFOA) as a " likely

carcinogen, " reporter Ken Ward Jr. of the Charleston (W.Va.) Gazette

learned that

in 1981 DuPont initiated a study to learn whether exposure to C8 caused

birth defects in the children of Teflon factory workers. When the study

found an excess of birth defects in the children, the study was

abandoned and the results filed away without notifying the federal

government.

Under the Toxic Substances Control Act (TSCA) companies must tell the

EPA when they find information " that reasonably supports the conclusion

that [a chemical] presents a substantial risk of injury to health. " [2]

 

Generating Doubt -- OSHA Gives Up

 

It is common practice for industry to wage scientific and public

relations war against the regulatory agencies whose job is to protect

public

health. The Wall Street Journal reports that PR firm executives openly

admit to hiring university professors to put their names on

ghost-written letters to the editor.[3] The letters are written by

hacks paid to

put a corporate " spin " on the science, and the experts sign their names

to lend credence to the spin (and to earn a fat fee).

 

Another common practice these days is " seeding the scientific

literature " with bogus results, to create doubt and confusion. In

recent years,

corporations have seeded the literature with false findings related to

tobacco, lead, mercury, asbestos, vinyl chloride, chromium, nickel,

benzene, beryllium and others. They cook the numbers, publish misleading

articles in obscure journals, and then cite their own work to create

confusion and doubt.

 

This strategy has brought the federal government to its knees. The case

of beryllium is illuminating. Beryllium is a strong, light metal used

in nuclear weapons and nuclear reactors. Beryllium dust is a potent lung

toxicant and carcinogen.

 

In 1999 the Department of Energy (DOE) set beryllium exposure levels

for federal workers that are ten times as strict as the general

industrial exposure standard set by the Occupational Safety and Health

Administration (OSHA). The OSHA standard was set based on data

available in

1949.

 

When OSHA proposed to tighten its safety standard for beryllium

exposure, to bring it into line with the new standard set for federal

workers,

industry was able to create enough doubt and confusion that OSHA backed

off and concluded that " more research was needed " before a tighter

standard could be justified.

 

A writer in Scientific American concludes that " OSHA administrators

have simply recognized that establishing new standards is so time and

labor-intensive, and will inevitably call forth such orchestrated

opposition from industry, that it is not worth expending the agency's

limited

resources on the effort. " [4] Creating confusion and doubt pays off.

 

Science in the Private Interest

 

Chester Douglass -- chairman of the Department of Oral Health Policy

and Epidemiology at Harvard -- is being investigated for concluding that

there is no relationship between fluoride in drinking water and bone

cancer in children. He himself cites research -- described as the most

rigorous to date -- concluding the opposite. The National Institute of

Environmental Health Sciences (NIEHS), which funded the research with a

$1.3 million dollar grant, and Harvard are investigating.

 

Why would a public health expert skew his results? Does it matter that

Dr. Douglass is the editor of The Colgate Oral Health Report, a

quarterly newsletter published by Colgate-Palmolive, which makes

fluoridated

toothpaste?[5] Professor Sheldon Krimsky, author of Science in the

Private Interest, warns that science in the public interest will

increasingly lose out as the entire system favors a tight

collaboration between

industry, government and academia.[6]

 

Academic scientists are under increasing pressure to find commercial

applications for their research so that their institution can patent,

license and profit from the work. Corporate partnerships and lucrative

consulting deals inject big money into the equation. In 1996, Sheldon

Krimsky analyzed the biomedical literature and found in 34 percent of the

articles, at least one of the chief authors had a financial interest in

the research. None of these financial interests was disclosed in the

journals. Krimsky said the 34 percent figure was probably an

underestimate because he couldn't check stock ownership or corporate

consulting

fees paid to researchers.[7] No wonder allegations of misconduct by U.S.

scientists are at an all time high. [1]

 

A recent survey of several thousand scientists found that 33 percent

had committed at least one of ten serious misbehaviors -- like falsifying

data or changing conclusions in response to pressure from a funding

source. Six percent admitted to failing to present data that contradicted

their own previous research.[8]

 

FDA, NIH Broken

 

The National Institutes of Health (NIH) and the U.S. Food and Drug

Administration (FDA) are now so thoroughly beholden to industry that they

are broken, unable to perform their duties to protect the public. The

New York Times reports " the White House and Congress forced a marriage

between the agency [FDA] and industry years ago for the rich dowry that

industry offered. " Dr. Janet Woodcock, deputy commissioner of operations

at the FDA said that the drug approval process is " pretty much broken

down... and has been for some time. " [9]

 

The FDA has become so focused on approving new drugs at the expense of

monitoring the ones already on the market that thousands of people have

been put in harm's way by drugs like Vioxx. One FDA analyst estimated

that Vioxx caused between 88,000 and 139,000 heart attacks -- killing

somewhere between 26,400 and 55,600 people (assuming 30 to 40 percent of

heart attacks were fatal).[4, 10]

 

An investigation into drug company ties with NIH scientists found that

more than half of those investigated had violated existing policies

meant to limit conflict of interest. Director of the NIH Elias Zerhouni

said, " We discovered cases of employees who consulted with research

entities without seeking required approval, consulted in areas that

appeared

to conflict with their official duties, or consulted in situations

where the main benefit was the ability of the employer to invoke the name

of NIH as an affiliation. " To his credit, Zerhouni ushered in reforms

banning NIH employees from accepting drug company consulting fees or

stock. But congress is now pressuring him to relent because NIH employees

have objected to the restrictions.[11]

 

To their credit, many courageous government scientists are now speaking

out about the corruption of science and there have been a number of

high profile firings and resignations ranging from the Fish and Wildlife

Service to NASA where scientists are blowing the whistle on government

abuses of solid science.[12]

 

Some 6,000 scientists including 48 Nobel laureates, 62 National Medal

of Science recipients, and 135 members of the National Academy of

Sciences have signed the Union of Concerned Scientists' (UCS) statement,

" Restoring Scientific Integrity in Policy Making. " The Bush government is

certainly not the first to abuse science, but they have raised the

stakes and injected ideology like no previous administration. The

result is

scientific advisory panels stacked with industry hacks, agencies

ignoring credible panel recommendations and concerted efforts to

undermine

basic environmental and conservation biology science.[12]

 

In the words of the UCS, " The actions by the Bush administration

threaten to undermine the morale and compromise the integrity of

scientists

working for and advising America's world-class governmental research

institutions and agencies... To do so carries serious implications for

the

health, safety, and environment of all Americans. " [12]

 

We have merely scratched the surface here. The corruption of the

scientific enterprise has proceeded very far. In some areas of scientific

endeavor, there are almost no independent researchers left because nearly

every scientist in the field is funded by corporations with an axe to

grind.

 

Agricultural biotechnology (genetically engineered food) is one such

field of inquiry. The flip side of that coin is that certain avenues of

research have been nearly eliminated by the funding sources -- for

example, researchers say funds to study the health effects of biotech

foods

are now almost non- existent. [13]

 

What does this all mean for science and society? The public's trust in

science will most certainly continue to erode. When this happens, even

honest science is tarnished and loses its power to protect nature and

public health because the public doesn't believe it. Honest science in

the public interest is becoming an endangered species. And America

slides further from democracy by and for the people.

 

 

 

 

 

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