Effect of an Oat Bran-Rich Supplement on the Metabolic Profile of Overweight Premenopausal Women

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Effect of an Oat Bran-Rich Supplement on the Metabolic Profile of Overweight

Premenopausal Women JoAnn Guest Jun 08, 2005 16:46 PDT

Vol. 49, No. 3, 2005

 

Free Abstract Article (References) Article (PDF 166 KB)

 

http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract & ProduktNr=\

223977 & Ausgabe=231143 & ArtikelNr=86149

 

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Original Paper

 

Effect of an Oat Bran-Rich Supplement on the Metabolic Profile of

Overweight Premenopausal Women

Julie Robitaillea, b, Bénédicte Fontaine-Bissona, Patrick Couturea,

André Tchernofa, c, Marie-Claude Vohla, b

 

aLipid Research Center, CHUQ-CHUL Pavilion, Ste-Foy, Quebec;

bFood Science and Nutrition Department and Nutraceuticals and Functional

Foods Institute, Laval University, Québec, and

cMolecular Endocrinology and Oncology Research Center, CHUQ-CHUL

Pavilion, Ste-Foy, Quebec, Canada

 

 

Address of Corresponding Author

 

Annals of Nutrition and Metabolism 2005;49:141-148 (DOI:

10.1159/10.1159/000086149)

 

 

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Key Words

 

Oat bran

Dietary fibers

Lipid profile

Women

Beta-glucan

 

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Abstract

 

Background/Aims: A healthy diet is a key factor in the prevention of

cardiovascular disease, the leading cause of death for women in

industrialized countries. In this regard, soluble fibers may have

beneficial effects on the plasma lipoprotein/lipid profile. The

objective of the present study was to investigate the plasma

lipoprotein/lipid response to dietary fibers in overweight premenopausal

women within a randomized controlled trial. Methods: Following a 2-week

run-in phase, 34 premenopausal women (age: 22-53 years) were randomly

assigned either to the control group (no supplement) or to the treatment

group, which received 2 oat bran-enriched muffins per day (28 g/day of

oat bran) during 4 weeks. Results: Supplementation with oat bran had a

beneficial effect on plasma HDL-C levels. Indeed, compared to the

control group (n = 16), a mean increase in plasma HDL-C levels of 11.2%

was observed in women eating the oat bran supplement (n = 1 (p = 0.01),

whereas the total cholesterol/HDL-C ratio decreased by 7.0% (p = 0.002).

Results were similar after adjustment for age, apo E genotype and weight

change. Conclusion: These results suggest that oat bran-rich foods have

beneficial effect on the metabolic profile of overweight women.

Integration of these foods as part of a healthy diet may, therefore,

improve the cardiovascular risk profile of women.

 

2005 S. Karger AG, Basel

 

 

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Author Contacts

 

Marie-Claude Vohl, PhD

Lipid Research Center, CHUQ-CHUL

2705 Laurier Blvd, TR-93, Ste-Foy, G1V 4G2 Québec (Canada)

Tel. +418 656 4141, ext. 48280, Fax +418 654 2145

E-Mail Marie-Cla-

 

 

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Article Information

 

Received: August 27, 2004

Accepted: January 24, 2005

Published online: May 31, 2005

Number of Print Pages : 8

Number of Figures : 2, Number of Tables : 4, Number of References : 49

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JoAnn Guest

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