Higher Content -18:1 TransFats in Subcutaneous Fat of Persons with Coronarographically Documented Atherosclerosis of the Coronary Arteries

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Higher Content -18:1 TransFats in Subcutaneous Fat of Persons with

Coronarographically Documented Atherosclerosis of the Coronay Arteries JoAnn

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Vol. 47, No. 6, 2003

 

Free Abstract Article (References) Article (PDF 68 KB)

 

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Original Paper

 

Higher Content of 18:1 Trans Fatty Acids in Subcutaneous Fat of Persons

with Coronarographically Documented Atherosclerosis of the Coronary

Arteries

 

 

P. Dlouhýa, E. Tvrzickáb, B. Stakováb, M. Veckab, A. ákb, Z. Strakac, J.

Fantad, J. Pachle, D. Kubisováa, J. Rambouskováa, D. Bílkováf, M. Andla

 

aDivision of Nutrition, 3rd Faculty of Medicine,

bDepartment of Medicine IV, 1st Faculty of Medicine, Charles University,

 

cDepartment of Heart Surgery, Královské Vinohrady University Hospital,

dDepartment of Surgery, 3rd Faculty of Medicine,

eDepartment of Anesthesiology and Resuscitation, 3rd Faculty of

Medicine, and

fDepartment of Statistics and Probability, 4th Faculty, Institute of

Economics, Prague, Czech Republic

 

 

Address of Corresponding Author

 

Annals of Nutrition & Metabolism 2003;47:302-305 (DOI:

10.1159/000072403)

 

 

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Key Words

 

Trans fatty acid isomers

Hardened fats

Atherosclerosis

Ischemic heart disease

 

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Abstract

 

Aim: To identify the total content of trans fatty acid (TFA) isomers and

C18:1 trans isomers in subcutaneous fat samples from persons with

atherosclerosis of the coronary arteries, as an indicator of dietary

exposure. Methods: Using capillary gas chromatography, the authors

determined total content of TFA isomers and C18:1 trans isomers in the

subcutaneous fat of 34 patients with ischemic heart disease who had

undergone aortocoronary bypass surgery and in 46 patients with no sign

of coronary disease. Results: On average, the total TFAs in cardiac

patients were 2.88 ± 1.19% of all fatty acids, in noncardiac patients

2.56 ± 0.89%. However, the difference is not statistically significant.

The average concentration of C18:1 trans in cardiac patients (2.31 ±

1.09%) was statistically significantly higher (p = 0.05) than in the

noncardiac group (1.95 ± 0.77%). Conclusions: The results obtained

indicate a lower TFA load in comparison with previous studies in other

countries. A higher concentration of 18:1 TFAs in the subcutaneous fat

of patients with coronary disease might be an impulse to correct the

dietary habits of this very high-risk population.

 

2003 S. Karger AG, Basel

 

 

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Author Contacts

 

Pavel Dlouhý

3rd Faculty of Medicine, Charles University

Ruská 87, CZ-100 00 Prague 10 (Czech Republic)

Fax +420 267102618

E-Mail Pavel.-

 

 

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Article Information

 

Received: January 3, 2003

Accepted: June 11, 2003

Number of Print Pages : 4

Number of Figures : 0, Number of Tables : 2, Number of References : 29

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