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[drugawareness] New SSRI for Premature Ejaculation - Dapoxetine

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atracyphd2

Fri, 27 May 2005 02:27:16 EDT

[drugawareness] New SSRI for Premature Ejaculation - Dapoxetine

 

 

 

 

In the article below the 20th paragraph reads:

Â

Dapoxetine is an SSRI-like drug designed for premature ejaculation. It is

superior to SSRIs because it moves quickly through the body and

doesn't need to

be taken daily, Althof said.

 

Did someone want to make sure the men were not being left out of this SSRI

nightmare? We already have women taking Prozac, under the brand name

Serafem,

for PMDD. Even though we have learned just over a year ago that PMDD is a

disorder that does not exist in England & the maker, Eli Lilly, has

warned that it

should not be taken by British women for this nonexistent disorder, US

women

apparently do suffer from this nonexistent disorder. Serafem (Prozac)

is what

they take for it once a month for about a week and then they stop

abruptly -

the worst way anyone can take an antidepressant.

 

Why is that the worst way to take one of these drugs? Withdrawal. The

body is

going in and out of withdrawal over and over again. This is such a

shock to

the brain and the entire glandular system that it can lead to some

very serious

reactions.

 

So, now, we are going to have men going in and out of withdrawal too

as they

take this drug to prevent premature ejaculation. SSRIs have been

promoted and

prescribed for this for a very long time now. And as I said in my book,

considering the effects of these drugs upon the sex drive over time,

you don't need

to worry about any kind of ejaculation at all. So in that sense these

drugs

are VERY effective in preventing premature ejaculation. I do not think

this is

the type of negative effect most men would expect from this new drug.

 

Of course what worries me most is that now we will have that many more men

suffering suicidal and hostile thoughts and actions, along with manic

reactions,

etc., due to the abrupt withdrawal. These would be triggered each time

it is

used and then abruptly discontinued - similar to what women have been

suffering as they go in and out of withdrawal each month taking

Serafem for PMS once a

month.

 

This is clearly a very dangerous idea, but then so was Viagra, and that is

still on the market as well.

 

But, since SSRIs produce suicide at double the rate, I cannot argue

with the

fact that suicide is a VERY effective preventative for premature

ejaculation.

 

Dr. Tracy

______________________

 

Dr. Ann Blake Tracy, Executive Director,

International Coalition For Drug Awareness

www.drugawareness.orgÂ

Author of the " Bible on Antidepressants, " Prozac:

Panacea or Pandora? - Our Serotonin Nightmare

& audio " Help! I Can't Get Off My Antidepressant! "

(Order: 800-280-0730)

_________________________

 

Â

 

http://www.palmbeachpost.com/business/content/business/epaper/2005/05/24/a1d_sex\

pill_0524.html

Â

 

New sex pill treats another malady

 

By Stephanie Horvath

 

Palm Beach Post Staff Writer

 

Tuesday, May 24, 2005

 

First there was Viagra for erectile dysfunction. Now Johnson & Johnson

soon

might sell a pill to prevent premature ejaculation.

 

If the Food and Drug Administration approves the drug, dapoxetine, it

would

become the first designed to prevent premature ejaculation,

potentially setting

it up to become the next Viagra in terms of sales.

 

 

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" I'm sure we'll have lots of jokes about this. I try to keep this

serious, "

said Stanley Althof, a West Palm Beach psychologist and one of the

investigators on the drug's clinical trials. " Nobody dies from rapid

ejaculation, but it

really is distressing. "

 

About 30 percent of men have this condition, according to the World Health

Organization, far more than the 12 percent who have erectile

dysfunction, which

Viagra treats.

 

" The market is huge, obviously. It's like when Viagra was introduced, "

said

Le Anne Zhao, an analyst for Caris & Co. in New York City.

 

Researchers released phase three clinical trial data for dapoxetine

Monday at

the American Urologist Association's annual meeting in San Antonio. Phase

three is the last of the trials before a drug seeks FDA approval. The

drug could

be on the market as early as the end of the year, Zhao said.

 

Johnson & Johnson declined to comment on the drug because the FDA is

reviewing it.

 

The clinical trial, which tested the drug on 2,614 men with premature

ejaculation, found that the men could increase their staying power

during intercourse

from about 55 seconds to an average of more than three minutes by

taking 60

milligrams of the drug one to three hours before having sex. This

compared with

one minute and 45 seconds for men taking the placebo.

 

The results fall short of those for healthy men, but Althof, who runs the

Center of Marital and Sexual Health of South Florida in West Palm

Beach, said

this would be a major improvement for men with premature ejaculation.

 

" If you were a man who ejaculated in 30 seconds, that would be like a

six-fold increase for that man, " he said. " That's a lot. While it

might not reach

where the normal men are, it's significant. "

 

Althof was the principal investigator on a study published in this month's

issue of the Journal of Sexual Medicine, which determined that healthy

men's

erections last an average of seven minutes after penetration. Anything

under two

minutes is considered premature.

 

Men in the clinical trial also reported sharp increases in sexual

satisfaction and control over ejaculation.

 

Dapoxetine could be a blockbuster drug for Johnson & Johnson. It could

have

$1 billion in sales, Zhao said. If and when it hits that mark depends

on men's

willingness to admit to needing the drug.

 

" Some men don't want to talk about it, so the market may take a long

time to

open up, " she said.

 

Dr. Bruce Kava, a urologist at the University of Miami who specializes in

cancer surgery and sexual dysfunction, said he thought sales of the

new drug

would increase slowly and won't be as strong as Viagra.

 

With erectile dysfunction, " there's a physical problem that's an

all-or-nothing situation, " Kava said, adding that studies have shown

that men with

premature ejaculation don't have a lot of sexual dissatisfaction.

" It's going to take

some coaxing from partners. "

 

Kava also said that, unlike erectile dysfunction, which affects primarily

older men, premature ejaculation affects men of all ages.

 

" You're dealing with a younger age group and they're less likely to

admit to

sexual problems, " he said. " Many of them might not realize they have a

problem. "

 

For years, premature ejaculation has been treated with behavioral

therapies

and was thought to be a psychological problem. More recently, doctors have

determined that the problem is partly biological and have begun

treating it with

selective serotonin reuptake inhibitors, or SSRIs, which are used to treat

depression. The SSRIs have a side effect of low sexual desire.

 

Dapoxetine is an SSRI-like drug designed for premature ejaculation. It is

superior to SSRIs because it moves quickly through the body and

doesn't need to

be taken daily, Althof said.

 

" I treat this psychologically and have for years. But we don't have a

lot of

trained sex therapists, " Althof said. " I think the most effective

treatment is

to take a pill and get counseling. "

 

 

 

 

 

 

 

 

 

 

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