The Bressler report JoAnn Guest

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The Bressler report

JoAnn Guest

May 07, 2005 08:04 PDT

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The Bressler report: one of the most damning documents

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http://www.presidiotex.com/bressler/

 

The Bressler report is one of the most damning documents about aspartame

in existence. While the original owners of the aspartame patent, the GD

Searle Company, were attempting to gain FDA approval of aspartame as an

additive in foods, they were obliged to conduct tests with laboratory

animals.

 

When the tests began turning out badly, as the lab rats turned up with

brain tumors, atrophied testicles, and other conditions and anomalies,

and many of them began dying unexpectedly, they began a shoddy job of

covering up the evidence. The FDA, which at that time was not under the

influence of aspartame sellers, like it is now, investigated Searle and

published a scathing, 76 page report uncovering the discrepancies,

inconsistencies, and evidence of fabrication of records in Searle's lab

work. They also performed their own autopsies on the remaining corpses

of the rats and found a large number of pathological conditions which

were caused by the aspartame but not reported by Searle in their

analysis of the results.

 

The Bressler report was obtained by a health activist, Barbara

Mullarkey, using the Freedom of Information Act. The FDA has since

passed into the control of persons with economic and political ties to

the new owners of the GD Searle Company - the notorious Monsanto

Corporation - makers of poisons and political intriguers who are number

one on the list of companies being watched by environmentalists

worldwide for their campaign of destruction of the environment and

disregard for human health in the name of corporate greed. The FDA,

prior to turning the report over to Mullarkey, blanked out some of the

attached charts and memos, as if they were some sort of state secrets.

 

The following is a statement by Barbara Mullarkey about the Bressler

Report:

 

 

 

" The l977 Food and Drug Administration's (FDA) Bressler Report remains a

key document against aspartame, the synthetic sweetener known as

NutraSweet and Equal. This 76 page report was the culmination of a

priority investigation at G. D. Searle's laboratory in Skokie, Illinois.

It compared all the available raw and summary data of an 115 week oral

tumorgenicity rat study, against the manufacturer's FDA submission.

 

" Jerome Bressler, the team leader, found missing raw data, errors and

discrepancies in available data, exclusions of animals, organ masses and

enlarged and atrophied organs. An undiagnosed uterine polyp increased

the incidence to 15 percent of the aspartame-dosed animals. The FDA's

Bureau of Foods officials chose to ignore the findings of the Bressler

Report.

 

" In l981, FDA Commissioner Arthur Hull Hayes, Jr., M.D. approved

aspartame in dry goods and in l983, Mark Novitch, acting for the

commissioner, approved aspartame in liquids. The 92 symptoms, in the

10,000 plus consumer complaints reported to the FDA, include those

suffered by the rats as noted in the Bressler Report. "

 

 

 

Dr. H J Roberts, MD, is considered by many to be a leading authority on

aspartame's effects on human health. The following are his comments on

the Bressler Report.

 

 

 

Forward to the Bressler Report by Dr. H. J. Roberts

 

In my book ASPARTAME (NutraSweet) IS IT SAFE? I discuss the aspartame

studies and their shortcomings. These are exerpts from the chapter: The

Myth of " The Most Thoroughly Tested Additive in History "

 

" Physicians and consumers who seek information from producers and

governmental agencies about reactions to aspartame products are offered

scores of reports published in scientific journals that seemingly

reinforce the issue of their safety. I have previously discussed the

major shortcomings of these studies. Let me summarize some of my

objections:

 

The failure of investigators to detect, or to report, tumors of the

brain, uterus and ovary to the FDA.

The failure of the senior investigator of a " negative " doubleblind study

on behavioral reactions (presented at an international conference) to

know, or to recall, the details of how the aspartame given to children

being tested was constituted and administered when I asked for such

information.

The failure of double-blind studies on patients with alleged

aspartame-induced headaches and seizures to use the same incriminated

commercial products (easily obtained in any store) rather than

aspartame-containing capsules.

The failure to test MALE mice for tumors of the urinary bladder

following aspartame implantation.

The failure of an investigator to even respond to my inquiry about his

published statistical data, from which he had concluded that aspartame

does not adversely affect non-insulin-dependent diabetics.

The failure of FDA administrators and attorneys to investigate animal

studies (particularly seizures in monkeys) before the five year statute

of limitations for prosecution expired - specifically, on October 10,

l977 and December 8, l977.

The failure of the FDA to act on a major concern expressed in

correspondence (dated January 10, l977) from Richard A. Merrill, its own

Chief Counsel. He requested a grand jury investigation of the

manufacturer for its alleged " concealing material facts and making false

statements in reports that the animal studies conducted to establish the

safety of the drug Aldactone and the food additive Aspartame. " Mr.

Merrill prophetically projected

" The FDA must receive the truth, not psychological warfare. To emphasize

the importance of safety data on aspartame, we note that if ultimately

approved for marketing, this sweetening agent can reasonably be expected

to be part of the daily diet of every American. "

 

The book continues and probably this is the most outrageous when

pathologists agree NOT TO COMMENT!

 

" The failure to challenge the manufacturer's contract with Universities

Associated for Research and Education in Pathology (UAREP). This private

group was engaged to determine the factual accuracy of prior aspartame

studies - but with the stipulation that UAREP " shall not express an

opinion " regarding either the design or safety significance of these

studies, nor make recommendations about the safety of aspartame for

human use! Dr. M. Adrian Gross also challenged the credentials of UAREP

relative to its ability to asses prior aspartame studies.

The failure of the then-FDA Commissioner, who had held this office only

several months, to heed the strong dissenting opinions of in-house FDA

scientists concerning aspartame licensure.

The failure of the NIH to renew research grants in basic pharmacology

concerning the metabolism of aspartame, notwithstanding prior

investigations that gave promise of major insights. One involved a

potentially simple blood test to detect a deficiency or genetic variant

of an enzyme responsible for the intestinal breakdown of

aspartylphenylalanine. "

So read now the Bressler Report, the priority investigation, that was

ignored, so that a neurotoxin was able to be approved and marketed for

human consumption.

 

Dr. H. J. Roberts

Sunshine Sentinel Press

_________________

JoAnn Guest

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