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I have heard so much about there being no evidence that eos can enter the

body except by inhalation or ingestion. That if you get any benefit from

external application it's because you inhaled some in the process.

Yet we do use different eos for different skin conditions. Seeming to

presume they will penetrate the skin.

(And, we hear the advice that if you have some eos whose purity you are

uncertain of to just use them for aromatherapy, don't ingest them. Seeming

to forget that they WILL end up in the body through inhalation.)

I am just reading Kathi Keville and Mindy Green's book on aromatherapy.

Kathi is editor of the American Herb Association Quarterly, an honorary life

member of the Nat.Inst. of Holistic Aromatherapy, and a foundng professional

member of the American Herbalist Guild. Has written three other books, on

herbs, and specializes in aromatherapy cosmetics. Mindy is an herbalist and

esthetician, and consultant in the aromatherapy industry. They write as if

it is a given that eos enter the body through external application.

Could we discuss this a bit? (Yes, a bit MORE!)

Thanks,

Shivani

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Hiya,

 

For sure! You're so right, there is much debate and maybe will be for a long

time

on " how " eo's enter the body. Though... one I'd guess can always call garlic eo

an exception (maybe), since if you put a drop on the bottom of the foot, you'll

taste it in your mouth.

Then, take lavender eo, another great example and one we use all the time here..

keep in " always " in the kitchen, the bathroom... all over the place. I've gotten

burned on the stove while cooking and immediately dabbed a bit of lavender oil

straight on my skin and never gotten a blister. Same with a cut, (small one) or

a

scratch - one drop and it'll usually stop the bleeding and kill the infection.

We've had cold sores from virus's in or on the sides of our mouths and we always

use a drop of lemon oil. Clears them right up.

While the same lemon oil, used 2-3 drops in dishwater will take the grease right

off your pots and pans and leave your skin feeling nice too... sad that

commercial products don't use the natural version of lemon oil but opt for the

chemical one instead........

Then there's rosemary and/or chamomile for hair conditioning.

One drop of tea-tree neat for a skin infection, covered by a band-aid. Clears up

the infection - we use that all the time too.

The list goes on and on...........and on!!! :)

So many 'experts' have so many varying opinions on this it's enough to confuse

us

all.

Ok, there's some to think about.. more from y'all? :) Good topic, interesting,

Shivani!

 

Hugs,

 

Marilyn

 

SArjuna wrote:

 

> I have heard so much about there being no evidence that eos can enter the

> body except by inhalation or ingestion. That if you get any benefit from

> external application it's because you inhaled some in the process.

> Yet we do use different eos for different skin conditions. Seeming to

> presume they will penetrate the skin.

> (And, we hear the advice that if you have some eos whose purity you are

> uncertain of to just use them for aromatherapy, don't ingest them. Seeming

> to forget that they WILL end up in the body through inhalation.)

> I am just reading Kathi Keville and Mindy Green's book on aromatherapy.

> Kathi is editor of the American Herb Association Quarterly, an honorary life

> member of the Nat.Inst. of Holistic Aromatherapy, and a foundng professional

> member of the American Herbalist Guild. Has written three other books, on

> herbs, and specializes in aromatherapy cosmetics. Mindy is an herbalist and

> esthetician, and consultant in the aromatherapy industry. They write as if

> it is a given that eos enter the body through external application.

> Could we discuss this a bit? (Yes, a bit MORE!)

> Thanks,

> Shivani

>

>

>

> My Pictures of Aromatic Plants and Exotic Places In Turkey

> http://members.home.net/chrisziggy1/triptoturkey.html

>

>

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Hello,

I am by far no expert and have no data other than my own personal

experience- I read that if you rub a clove of garlic on your foot

that within 30 mins your breath will smell of garlic( yes I tried it

and it worked- than brushed :)

My husband is allergic to asprin and most OTC cold medications, he

suffers from back pain, so I gave him a massage using lavender,

ylang ylang and geranium rose in a Grapeseed base, he felt tremedous

relief, but I was surprised when he asked later if I could put a

bowl of the oil I was using where he could smell it - I smell it as

I was applying it but apparently on the table with his head faced

down he could not smell it. Just my observation as I said I am not a

expert but I do think that you can get the benefits from skin

absorbtion, given my husband has a very low pain tolerance and is a

big baby when it comes to pain, if he did not feel better he would

definetly not be shy in telling me

Just my 2cents

Emryldgea

 

 

 

, SArjuna@a... wrote:

> I have heard so much about there being no evidence that eos

can enter the

> body except by inhalation or ingestion. That if you get any

benefit from

> external application it's because you inhaled some in the process.

> Yet we do use different eos for different skin conditions.

Seeming to

> presume they will penetrate the skin.

> (And, we hear the advice that if you have some eos whose

purity you are

> uncertain of to just use them for aromatherapy, don't ingest

them. Seeming

> to forget that they WILL end up in the body through inhalation.)

> I am just reading Kathi Keville and Mindy Green's book on

aromatherapy.

> Kathi is editor of the American Herb Association Quarterly, an

honorary life

> member of the Nat.Inst. of Holistic Aromatherapy, and a foundng

professional

> member of the American Herbalist Guild. Has written three other

books, on

> herbs, and specializes in aromatherapy cosmetics. Mindy is an

herbalist and

> esthetician, and consultant in the aromatherapy industry. They

write as if

> it is a given that eos enter the body through external application.

> Could we discuss this a bit? (Yes, a bit MORE!)

> Thanks,

> Shivani

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This biggest controversy about this subject is not so much whether any

part of any EO enters into the bloodstream when applied topically, but

WHAT actaully does enter into the bloodstream and HOW much of it. In the

world of AT and wholistic therapies we often discuss the importance of

plant synergy, and using whole oils (not adulterated) because of that

special synergy of so many ingredients, some in very minute quantities,

that makes it all work so wonderfully, but we may not be getting that

synergy we are looking for when applying oils topically for ceratin

things, cause the part that may make a certain oil work so wonderfully

may not even be absorbed ..... :)

 

Penetrating into the upper layers of skin to help a dermatitis of some

sort and absorbing into the bloodstream via the skin in great enough

quantity to do much benefit to an entire system (for example) are two

totally different animals too :)

 

SOME chemicals are going to be absorbed .. some won't, some more so than

others ..... but nobody has done (and it doens't seem anybody will be

doing) tests to see JUST HOW MUCH and of what does truly get absorbed

into the bloodstream from EO's.

 

Like Tea Tree Oil can effectivly be used for bladder infections is true,

BUT applying it topically to your belly isn't gonna do squat for that

though ;)

 

*Smile*

Chris (list mom)

http://www.alittleolfactory.com

 

SArjuna wrote:

 

> I have heard so much about there being no evidence that eos can

> enter the

> body except by inhalation or ingestion. That if you get any benefit from

> external application it's because you inhaled some in the process.

> Yet we do use different eos for different skin conditions.

> Seeming to

> presume they will penetrate the skin.

> (And, we hear the advice that if you have some eos whose purity

> you are

> uncertain of to just use them for aromatherapy, don't ingest them.

> Seeming

> to forget that they WILL end up in the body through inhalation.)

> I am just reading Kathi Keville and Mindy Green's book on

> aromatherapy.

> Kathi is editor of the American Herb Association Quarterly, an

> honorary life

> member of the Nat.Inst. of Holistic Aromatherapy, and a foundng

> professional

> member of the American Herbalist Guild. Has written three other

> books, on

> herbs, and specializes in aromatherapy cosmetics. Mindy is an

> herbalist and

> esthetician, and consultant in the aromatherapy industry. They write

> as if

> it is a given that eos enter the body through external application.

> Could we discuss this a bit? (Yes, a bit MORE!)

> Thanks,

> Shivani

>

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for years medical doctors have said that the skin is a dead layer of

cells and nothing is going thorough that layer.. then also years ago now

they came out with the patch medications.. hormones and such medication

right through the skin viua patches, cant have it both ways?

 

essential oils enter one way or another..

 

it seems to me that just like many other semi permeable membranes in the

body the skin will be open to some and closed to others... the nervous

system will be susceptible to some things and not to others... so...

maybe it is both.. open and closed...

 

i wonder if like.. something very bitter wormwood ?.. the body would

close off to it... or maybe not ... or like what I did with my rose otto

... I got a large mister and put a few drips of rose otto and bottled

fizzy water

Perrier and Gerolsteiner to be exact. and shook it up and misted with it

is a delicate rose water... hay it works..

 

While at it I would like to see the many ways of using the rose oils...

god it is a great scent... also gave it to my wife and her mentor...

 

how do y'all like to use it best?

 

 

 

SArjuna wrote:

>

> I have heard so much about there being no evidence that eos can enter the

> body except by inhalation or ingestion. That if you get any benefit from

> external application it's because you inhaled some in the process.

> Yet we do use different eos for different skin conditions. Seeming to

> presume they will penetrate the skin.

> (And, we hear the advice that if you have some eos whose purity you are

> uncertain of to just use them for aromatherapy, don't ingest them. Seeming

> to forget that they WILL end up in the body through inhalation.)

> I am just reading Kathi Keville and Mindy Green's book on aromatherapy.

> Kathi is editor of the American Herb Association Quarterly, an honorary life

> member of the Nat.Inst. of Holistic Aromatherapy, and a foundng professional

> member of the American Herbalist Guild. Has written three other books, on

> herbs, and specializes in aromatherapy cosmetics. Mindy is an herbalist and

> esthetician, and consultant in the aromatherapy industry. They write as if

> it is a given that eos enter the body through external application.

> Could we discuss this a bit? (Yes, a bit MORE!)

> Thanks,

> Shivani

>

>

>

> My Pictures of Aromatic Plants and Exotic Places In Turkey

> http://members.home.net/chrisziggy1/triptoturkey.html

>

>

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Here is Martin Watt's spin in the subject ...

 

*Smile*

Chris (list mom)

http://www.alittleolfactory.com

 

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

 

http://www.aromamedical.demon.co.uk/articles/skinabso.html

 

ESSENTIAL OILS THEIR LACK OF SKIN ABSORPTION,

BUT EFFECTIVENESS VIA INHALATION.

 

By Martin Watt

 

Original version published in Aromatic Thymes. 1995. Vol. 3. No. 2. 11-13.

 

Note: An extra article has been added at the bottom of this one.

 

PREFACE: I am anxious that people do not misconstrue my articles as

indicating that I don't think aromatherapy works. This is far from the

truth as I wholeheartedly agree the therapy can have wonderful healing

benefits. However, I am certain some of the traditionally held views on

how it works are misleading.

 

Aromatherapy can be a potent therapeutic tool for unlocking the brains

inhibition of normal bodily processes due to various emotional factors.

It is excellent for giving relief from many musculo-skeletal ailments.

Essential oils can achieve spectacular results when treating various

kinds of skin trauma. However, much confusion and misinformation exists

about two relatively separate forms of treatment:-

 

(1) massage.

 

(2) The use of aromatic oils with or without massage.

 

Therapeutic activity: Some of the aromatic 'essential' oils used in

aromatherapy do have well-documented therapeutic actions. However, many

of the oils for which aromatherapists claim physiological medical

activity, in fact possess no recorded historical medicinal actions. Oils

such as Moroccan chamomile, Citronella, Clary sage, Geranium, Rosewood,

Vetiver and Ylang were originally produced solely for the perfumery and

fragrance trades.

 

On the other hand, certain oils such as aniseed, cubeb, dill, fennel,

peppermint, rose, sandalwood, etc. have been used over several hundred

years for a variety of ailments. However, such oils have mainly been

used internally as medicinal agents. The vast majority of reports in

aromatherapy, about their therapeutic activity, are based on information

gleaned from the ORAL consumption of traditional remedies.

 

Many of the essential oils for which aromatherapists claim explicit

physiological effects such as: " Fennel is diuretic, " " Geranium regulates

the hormonal system, " " grapefruit is good for cellulite. " Cannot be

demonstrated to have direct physiological actions when these oils are

applied to the skin during massage . Fennel for example is well known

for producing an increase in urine output when it is consumed as a

medicine. However when the volume of essential oil used in the average

massage is applied, it is very doubtful that enough essential oil can be

absorbed through the skin to elicit any diuretic action. If very large

amounts are used, the skin is occluded (such as with compresses), or the

essential oil is used in hot humid environments, then I am prepared to

accept a fair amount of oil gets into the subcutaneous tissues. Diuresis

however, has, in fact, been proven to occur following ordinary massage

without the use of any essential oils.(1)

 

 

I believe the major modes of action of essential oils used in

aromatherapy are:

1. The psychotherapeutic effects of the oils on the olfactory system and

the brain.

 

2. The absorption into the circulation of some of the oils constituent

chemicals via

the nasal membranes and lungs.

 

3. For muscular problems, if very much higher percentages of essential

oil than are

normally used in massage are 'rubbed in' or applied on compresses.

 

4. Damaged skin can often benefit from using 'healing' essential and

fixed oils. This

form of treatment may not be strictly 'aromatherapy', but it is closely

allied. This

is because the essential oils can have a direct pharmacological action on

damaged tissues, as well indirect beneficial effects on the mind if the

aroma is

pleasant.

 

 

 

The effects of essential oils on the brain via the olfactory system.

 

This is the basis on which the perfumery trade functions, and is the way

I believe most aromatherapy works. The fragrance trades have sponsored

substantial research on the psychological effects of aromatic

substances. It has been clearly demonstrated in animals and humans that

the brain wave patterns are affected to quite a remarkable degree when

aromatic vapours are inhaled. I t has even been shown that brain wave

patterns are altered, when human subjects inhaled aromatic vapours at

such a low level that they said, " they could not smell the substance

that was being administered. " This experiment in particular clearly

demonstrates that the human sense of smell is much more acute than it is

normally credited with.

 

Perfume manufacturers have based their business around the effects that

certain perfumes can have on the emotional state of both the wearer and

people they come into contact with. Therefore, businesses that worldwide

are worth billions of dollars, are largely based on the psychological

and emotional effects of fragrance. It is therefore somewhat peculiar

that this most important aspect of the use of fragrant plant oils, is

not the linchpin of aromatherapy. Rather most courses insist on

dogmatically sticking to the hypothesis that the oils achieve a

pharmacological effect by being absorbed through the skin and into the

circulation.

 

 

 

Skin absorption of essential oils.

 

I remain extremely skeptical that this is a route by which significant

volumes of most essential oils can enter the body. After years of

looking at so called 'scientific' research, I have failed to find one

trial where the methodology used has been adequate (2). Generally

researchers have taken no precautions to prevent the inhalation of the

volatile molecules. This is the critically important area that I have

found time and time again being overlooked by researchers. They always

fail to understand the fundamental nature of most essential oils, which

is that they are extremely volatile substances. As such, they quickly

find their way into the respiratory tract epithelium and thence to the

bloodstream.

 

Currently a lot of theoretical skin biology is being taught in

aromatherapy courses. Most tuition is based on theoretical models of how

essential oils may be metabolised once they have gained access to the

layers of skin where enzymatic reactions are known to occur. As a small

number of drugs are now administered in the form of skin patches, this

is promoted as being " conclusive evidence " that essential oils are

freely absorbed in a similar manner. Yet, even hormone patches require

the solution of the hormones in ethyl alcohol in order to permit their

absorption by the skin.

 

Scientific references supplied by various authors about 'evidence of

skin absorption' frequently refer to experiments of little relevance to

aromatherapy such as:

 

1. Individual fragrance chemicals (usually synthetic) are used-not the

WHOLE oil with its hundreds of different chemicals. (3)

 

2. The substance being tested has often been applied under occlusion

(covered),(4) which does force the substance into the skin. However,

this ignores the fact that when essential oils are used in massage, body

heat will quickly evaporate the vast majority of the highly volatile

chemicals away from the skin, thus permitting quick inhalation.

 

The use of a vegetable carrier oil probably makes little difference to

the amount of essential oil absorbed by the skin. This is because the

volatile chemicals in essential oils evaporate within seconds of

application to a warm area. Also, the rate of evaporation from the skin

is likely to be substantially enhanced by the heat generated by the

massage. Again, I have to remind you that even when using carrier oils,

you can quickly smell the essential oils used. The mere fact that you

can smell them means the vapours are gaining immediate access to the

respiratory tract.

 

3. Of Major importance, is the most fundamental error of all research

that I have come across-no precautions have been taken to prevent

inhalation of the essential oil vapours. I have read all of the paper

published by Rommelt et al. in 1974(5). However in the oft quoted 1974

paper, aromatherapy writers and some scientists, simply overlook the

fact that 150 ml. of Pine oil was added to the bath of the subject, and

no mention was made of how he breathed. It does not surprise me that he

excreted a-b-pinene and camphene for several days. How on earth can

anyone compare the effects of 150 mls. with the few drops of essential

oils used in the average massage.

 

This team published a subsequent paper, (10) on absorption of essential

oil compounds from a bath, this time inhibiting breathing of the

vapours. They subsequently detected fragrance chemicals in the blood.

However the use of essential oils in a bath is nothing like the same as

their use in aromatherapy massage. I know that in the presence of heat

and more importantly humidity, that the skin will absorb compounds.

Again in this experiment far larger volumes of oil seem to have been

used than are used in massage.

 

The same researchers indicated there might be some absorption of

essential oils from ointments. Indeed, there may be a little absorption

by this method, but I do not know if the inhalation factor was excluded

in any trials. Ointments have an extremely ancient history of being used

as local applications for musculo-skeletal problems, but there is little

sound data suggesting that the volume of essential oils, so absorbed,

can have anything other than a localised effect.

 

I am not aware of any evidence suggesting that enough essential oil is

left in the bloodstream to have any effects on other organs. Until

experiments are conducted with the people being massaged having an air

supply under pressure and from a remote source, then all these tests are

unreliable. Interestingly no one in complementary medicine seems

interested in sponsoring such a simple trial, I wonder why?

 

4. In fact, there is far more evidence to support the opposing view,

that most essential oils are NOT FREELY ABSORBED. Human skin seems to

more readily permit the absorption of a number of water soluble plant

chemicals such as the nicotine anti-smoking patches, nicotine being a

water-soluble alkaloid. Many national pharmacopoeias contain

formulations for lotions, creams and ointments for painful conditions

such as sciatica, neuralgia & arthritis based on water soluble plant

alkaloids. There is, however little evidence to support the theory that

human skin will readily permit the passage of the lipid (fat) soluble

portions of plants (barring a few exceptions). In traditional medicine,

we find few examples of plant oils being used for anything other than

localised treatments. Fixed and volatile plant oils have always been

used principally for cosmetic and skin care purposes.

 

Of utmost importance, is not if essential oils are absorbed into the

superficial dead layers of the skin, as clearly this does occur. But,

does sufficient find its way into the body via the skin to have any

clinical effects? My investigations of dermatological literature have

led me to the following conclusion: When a few natural chemicals in

essential oils are absorbed by the skin, with a few exceptions, it is

found that those same essential oils are well documented as causing

adverse dermal and systemic reactions. This seems to me to indicate that

many essential oils are alien to the immune system when they are taken

into the body via the skin.

 

 

 

I offer the following evidence on skin absorption or the lack of it.

 

The monographs published by the R.I.F.M. provide the following unless

indicated. There is insufficient space to give full references, but they

are available in those monographs. I must add here, that even where

absorption of volatile chemicals has been indicated, without exclusion

of the inhalation factor the results must still remain questionable.

 

CHEMICALS

(frequently not natural but synthetic)

 

ABSORBED through the skin of animals. NOTE: human skin is far less

permeable than animal skin.¾ Benzyl acetate, benzoic acid, camphor,

d-carvone, cinnamic acid, coumarin, para- cymene, d-limonene, methyl

salicylate, a -phellandrene, terpineol, a -b -pinene & camphene.

d-limonene; only 3% was absorbed in vitro across isolated human skin,

while in rats the figure was 6%.6

 

AUTHORS NOTE: One probably gets higher levels of d-limonene in the blood

from eating orange flavoured drinks, candies, cakes, liqueurs, etc.

 

 

NOT ABSORBED:

 

linalool within 2 hours of application.(7)

 

d-pulegone in pennyroyal.

 

carvacrol in some thymes and mints.

 

eugenol, isoeugenol & methyl benzoate in clove, tuberose and ylang.

 

fenchone in anise, fennel & some lavenders.

 

geraniol in geranium & palmarosa.

 

Evening primrose (fixed oil).¾ Not absorbed through the highly permeable

skin of premature babies, but it was thought that water and oil

emulsions (creams or lotions) may be more favourably absorbed. (8)

 

 

 

 

WHOLE ESSENTIAL OILS

 

ABSORBED:¾cumin, tansy.

 

NOT ABSORBED:¾Lavender(see ref. above on linalool), tolu balsam oil,

copaiba balsam oil, parsley seed, patchouli, pimenta berry and leaf.

 

 

 

The systemic absorption of aromatic molecules via the nasal passages and

lungs.

 

This method by which aromatic molecules in essential oils gain access to

the body has been demonstrated. When Rosemary oil vapours were

introduced into the atmosphere of caged mice, it was shown that blood

samples contained a substantial proportion of one of the chemicals

present in the inhaled essential oil. This proved the volatile chemicals

in essential oils can gain access to the bloodstream in significant

amounts, if the concentration in the atmosphere is at an appreciable

level.(9) UPDATE: Since the time of writing, trials on humans have

confirmed that indeed, significant volume of essential oils do gain

access to the blood via the respiratory tract.

 

As the brain is a 'blood hungry' organ then clearly the first port of

call for aromatic molecules absorbed via the olfactory epithelium is

likely to be the brain. It is of course, well known that certain drugs

are known to act extremely quickly when they are sniffed up the nose.

 

CONCLUSION:

 

I believe it is likely that we get a complexity of effects when

essential oils are inhaled:

 

1) A direct pharmacological effect via the blood supply to the brain.

 

2) An indirect effect via the olfactory nerve pathways to the brain.

 

3) The beneficial effects from the massage and the touch receptors.

 

4) The good old powerful placebo effect, caused by client therapist

interactions.

 

5) Possibly, a regulation of energy flows via similar pathways to

accupressure/acupuncture.

 

With that kind of bombardment, it's not surprising that aromatherapy can

achieve such excellent results. The therapy clearly is potent at

reducing the brains inhibition of the body, from carrying out its

routine regulating and healing activities.

 

 

1. E. Ernst M.D. et al. 1987, Physiotherapy vol. 73, no. 1.

 

2. J. Buchbauer et al. Jan-Feb. 1992. J. of Am. Soc. of Cosmetic Chemists,

43; 49-54.

 

3. Bronaugh et al. 1990. Fd. & Chem. Tox. 28, (5), 369-373.

 

4. Hotchkiss et al. 1992. Fd. & Chem. Tox. 28, (6), 443-447.

 

5. H. Rommelt et al. 1974. Munch. Med. Wschr. 116, 537.

 

6. S. Hotchkiss, St.Mary's Hospital, London. Published; New Scientist,

Jan 1994,

p.24-27.

 

7. Meyer & Meyer 1959, Arzneimittel-forsh 9,516.

 

8. E.J.Lee et al. Arch. Dis. in Childhood 1993,68: 27-28.

 

9. K. Kovar et al. 1987. Planta Medica 53, 315-318.

 

10. H. Roemmelt, H. Drexel and K. Dirnagl Die Heilkunst, Vol 91, no. 5,

1978

 

Original © 1995 Martin Watt. Revised 1999.

 

 

--

 

--

 

The article below was sent to the I.J.A. in April 1995 but was never

published. It seems it " Never arrived " ! It is a little dated but most

points are still as valid today as 5 years ago.

 

 

 

Cutaneous Absorption (or the lack of) of Essential Oils

 

by Sylla Sheppard Hanger and Martin Watt

 

Do essential oils penetrate the skin into the bloodstream?

 

This is a very confusing issue in the aromatherapy literature as most

sources say the skin readily absorbs essential oils into the bloodstream

and this is the route by which significant volumes of oils can enter the

body. They say this is not only because the skin is the largest organ,

but also because some essential oils are extremely lipophilic in nature,

and the molecular structure of essential oils is very small.

 

Research has proven the penetration ability of several drugs now

administered in the form of patches, and it is assumed that essential

oils are similarly absorbed. However, by investigating a wide range of

dermatological literature, one can find much more evidence to support

the opposite view. Whole essential oils are not freely absorbed and very

few essential oil constituents are absorbed through the skin into the

bloodstream. Most chemical constituents would be absorbed into the

circulation in reasonably significant amounts via nasal membranes and

lungs if the concentration in the atmosphere is at an appreciable level.

 

Human skin has developed as a highly effective barrier. Little evidence

shows, with a few exceptions, that the skin will readily admit lipid

soluble portions of plants. Almost without exception (an exception may

be chamazulene), the small number of natural chemicals present in

essential oils which are slightly absorbed by the skin, are also well

documented as causing adverse dermal reactions. This would seem to

indicate that a wide range of essential oils are alien to the immune

system when taken into the body via the skin. Nevertheless, the

important question remains whether sufficient quantities enter the body

through the skin to have any beneficial pharmacological effects. And,

yes, in spite of this, aromatherapy still works! It is just the method

it is assumed it works by is not correct. Certainly it works

symptomatically by external application on superficial skin layers

(i.e., as antiseptic, anti-inflammatory, etc.) and more importantly in

some cases, via the mind.

 

Based on theoretical models of how the skin is constructed and of how it

should work, it is assumed that essential oils can pass through this

tough barrier. Yet, skin absorption of whole essential oils has not been

definitely shown. It is assumed, at least in theory that substances with

low molecular weight will penetrate the skin. Essential oils and their

naturally occurring constituents are mostly below 1000 m (m = molecular

weight). It is also said that " due to their lipophilic nature " , some

essential oils and vegetable oils have an affinity to the skin, thereby

allowing their passage into the bloodstream. It is also said that " due

to this lipophilic nature, essential oils are soluble in fat and some

fat-dissolving oils (high in ketones) are said to he able to dissolve

the myelin sheath around nerves promoting " neuro " -toxicity " .

 

First of all, if essential oils managed to get into living cells in

sufficient quantity to dissolve the fat then it would certainly also

kill the cell(s). The test of putting a drop of thuja on chicken fat and

seeing it dissolve (as advocated by some) is not considered " proof " and

cannot at all be compared to use in aromatherapy (at least any more than

watching a drop of lavender eat a hole in a styrofoam cup.

 

Citing patch medications and garlic applied to the feet (then detecting

on breath) is also incorrect as evidence of penetration through the

skin. Application of occluded concentrated chemicals cannot be compared

to essential oil application in aromatherapy. And garlic has a chemical

composition totally different to any other essential oil. Because of its

fantastic volatility, inhalation is impossible to avoid (most people

have to leave the room when a bottle is opened). Yes the oil gets in the

body, but by being inhaled and then excreted on the breath for hours

afterwards. In spite of all this, there remains no substantial evidence

of whole essential oils having been detected in the bloodstream in

clinically active amounts following skin application.

 

Secondly, we use carrier oils for skin application; the molecules of

vegetable oils are much larger than essential oils, and in spite of

their lipophilic nature, are also unable to pass through the skin 1. The

theoretical model advocated is that skin is relatively permeable to fat

soluble molecules and impermeable to water and salts; and because cell

membranes have a lipid bilayer, it seems possible that fat soluble

molecules can pass through. However, most vegetable oils (including

essential oils contained within them) have been found to reside in the

outer dead layer of skin without penetrating into the bloodstream. In

addition, viscosity or degree of saturation of the vegetable oil plays a

part in ability of penetration. Almond and olive oil were shown to

penetrate the outer skin layer slowly (mono-unsaturates) in abdominal

guinea pig skin, while linseed, rich in polyunsaturates, penetrated

rapidly. Because of this fact, the external emollient qualities of

vegetable oils cannot be denied, therefore they are highly suitable as

carriers for essential oils.

 

What does penetrate the skin?

 

Because sensitisation reactions have been experienced, it seems some

components of essential oils must pass into the skin. However, it is

very difficult to find substantial scientific evidence that the

absorption is of pharmacological significance (i.e., the amount absorbed

causing systemic reactions such as diuretic). The whole oil does not

appear to be absorbed into circulation through the skin at all. The main

reference sources cited as evidence that skin absorption occurs have

several areas of uncertainty that cannot be denied.

 

Certain constituents (i.e., a-pinene, camphene) are both absorbed in

possibly significant amounts, as shown in tests with pine oil in a hot

bath (combined with heat and humidity) and using a nose clip to avoid

nasal inhalation. Both chemicals were found to be excreted in the urine

for up to twenty-four hours later.2 However, this experiment in a hot

tub cannot be equated with an aromatherapy massage.

 

Benzoic acid (benzoin) is well known to be readily absorbed and has been

used to test variability of absorption over the body. Inner forearms and

back were found to be the best sites. Benzyl acetate (jasmine) has been

recovered from urine 24 hours after neat application and both jasmine

absolute and synthetic jasmine have been shown to produce irritation

reactions. Benzyl benzoate (ylang ylang) and benzyl alcohol (up to 30%

of Peru balsam) were absorbed within 24 hours. Cinnamic alcohol

(cinnamon leaf & benzoin), cinnamic acid (cinnamon bark), both severe

sensitising agents, and safrole (sassafras), a carcinogen, are also

absorbed. Cinnamic aldehyde (cassia, cinnamon bark) was absorbed well

following neat application and is not advised due to strong sensitising

potential. Methyl salicylate (sweet birch, wintergreen) is also freely

absorbed, especially in the presence of water. The ease of absorption of

the above constituents may be why they are irritants or sensitisers.

However only a few molecules are required to trigger a sensitisation

reaction.

 

Many of the skin permeability tests used occluded (covered) isolated

concentrated synthetic aroma chemicals as the prototype for essential

oils,3 which cannot compare to the whole essential oil. And no studies

found on skin absorption used a mask to prevent absorption into the

bloodstream from breathing the volatile components in through the lungs;

with the exception of the pine oil bath test cited above (which

inhibited nasal breathing and fails to state how the person breathed as

there was no mention of oxygen apparatus in the methodology).

 

Some of the dermatological tests may be unreliable when compared to

humans as they were unfortunately conducted on animal skin, which is

considered by leading dermatologists to be far less absorbent than human

skin. Tests in vitro on isolated chemicals mentioned previously are

unreliable when compared to the whole oil, and when compared to in vivo

situation; however, care should be taken when using oils, which contain

these chemicals in significant quantities.

 

In vitro studies on human (breast tissue, foreskin) and animal skin

showed benzyl acetate was rapidly absorbed, creating a reservoir in

upper dead cell layer.4 This indicates that a major proportion of

essential oils applied to skin may leave by evaporation, rather than

passage through. Ethyl alcohol, a major part of perfumes, enhances

percutaneous absorption and a recent study showed 75% of fragrance was

absorbed through the skin when occluded (covered) regardless of the

fragrance, as opposed to uncovered.

 

Testing with the whole oil (lavender) diluted (2%) and applied to human

skin, still only showed a few individual chemicals (linalool and linalyl

acetate) in the bloodstream. The test methodology did not indicate any

other amounts detected or if other constituents were even tested for.5

Again, no breathing apparatus was used to prevent lung absorption,

thereby, not satisfying the question of skin absorption of whole

essential oils. Note: Since writing a similar test was done using a

single chemical and breathing apparatus. The volume of chemical in the

bloodstream was of no pharmacological significance when related to the

volume an aromatherapist would use in a massage.

 

In addition, because the skin is an important site of metabolism of

drugs and solvents, essential oils may be changed before the permeable

constituents can enter. Essential oils may undergo molecular

transformation by skin enzymes (P450's). Benzyl acetate (jasmine) is

broken down very effectively by esterase enzymes in the skin.

 

Increasing the permeability of the skin is possible and can be achieved

by several means. It must be remembered that increased permeability can

also mean increased irritation and sensitisation with any essential oil.

Hypersensitive or atopic persons (i.e., those suffering from hayfever,

allergic rhinitis, eczema, asthma, wool or animal intolerance, or a

family history of any of these) require greater caution. Caution is

needed with irritating or sensitising oils when any of the following

factors are present.

 

The following have been shown to increase permeability of the skin.

 

Temperature -skin (hence caution during or after exercise, sauna)

 

therapy room

 

therapists hands

 

bath water

 

Humidity, presence of water - after soaking for a while the normally

water-resistant skin becomes hydrated, thus more permeable.

 

Addition of detergent, soaps and solvents have been shown to increase

permeability.

 

Damaged or abraded skin absorbs easier thus irritation and sensitisation

reactions are possible (i.e., eczema, psoriasis, wounds).

 

Occlusion - covering the area aids penetration by preventing evaporation.

 

SUMMARY:

 

It still remains to be shown that whole essential oils penetrate through

the skin into the bloodstream, especially in any significant amounts,

although single constituents may. Therefore, the statement that " whole

essential oils pass into the bloodstream through the skin " is incorrect.

They do enter the bloodstream very quickly through respiration, if the

amount in the air is appreciable, therefore appearing in blood or urine.

However, of the few constituents that may penetrate, besides being

mostly irritant and sensitising, the amounts received in aromatherapy

massage or needed to cause systemic pharmacological actions remains to

be determined. It may be, therefore, that many of the actions claimed

for essential oils may be due to inhalation, or to unreliable

extrapolation of the internal ingestion (of oil or herbal extract) and

may not apply to amounts absorbed through skin application. The question

of VOLUME of oil or its constituent chemicals getting into the

bloodstream via the skin is of critical importance because most people

take in far more essential oils in food and drink.

 

Just because whole essential oils may not be absorbed via skin into the

bloodstream creating a systemic reaction, does NOT mean beneficial skin

affects and certainly the mental effects (relaxation) are very much

possible with essential oil treatments. Skin treatments affect the

external layers where many problems are found. The antimicrobial and

anti-inflammatory properties, as well as others, have proven essential

oils remain quite efficient at treating many minor complaints. And the

relaxing mental effects produced from the joy of using a pleasing

fragrance will never be denied.

 

 

1. From " Application of Oil in Prevention of Fatty Acid Deficiency in

Pre-term Infants " . Lee F. Gibson K. Zimmer K. Food & Chemical

Toxicology, Vol. 28, Jan. 1985. pgs. 27-28, & Vol 6, 1 990. Showed

topical application of safflower oil does not decrease fatty acid

deficiency; found no evidence at all of trans-dermal absorption.

 

2. 'Percutaneous absorption of Essential oil and Compounds'. Rommelt, et

al 1974, Kosmet Database.

 

3. Bronaugh, et. al, Food & Chemical Toxicology, 28 (51, 369-373, 1990.

'In vivo percutaneous absorption of fragrance ingredients in rhesus

monkeys and humans'.

 

4. Hotchkiss at. al. Food & Chemical Toxicology. 28 (6), 443-447, 1990.

'Percutaneous absorption of benzyl acetate through rat skin in vitro.

Validation of an in vitro model against in vivo data'; and Hotchkiss et.

al. Food & Chemical Toxicology. 30 (2), 145-153, 1992, 'Percutaneous

absorption of benzyl acetate through rat skin in vitro. Effect of

vehicle and occlusion'. In which only 4% was absorbed (Bronaugh. 1990)

 

5. Buchbauer, J. G, Jirovetz. Firtzer, Journal of Society of Cosmet/c

Chemists, 43;49-54, Jan-Feb 92; " Percutaneous Absorption of Lavender

from a Massage Oil; " after a 10 minute massage on a male adult stomach

area, showed traces of linalyl acetate and linalool (only) within five

minutes in the blood, with maximum concentration in 20 minutes and

elimination within 90 minutes.

 

Bibliography

 

Buchbauer, J.G., Jirovetz, Firtzer, Journal of Society of Cosmetic

Chemists 43:49-54, Jan-Feb, 1992.

 

Hanger, Sylla Sheppard, Lisin, G., Watt, M., Moyler, D., (eds.), The

Aromatherapy Practitioner Reference Manual, 1995.

 

Hotchkiss et al. Food & Chemical Toxicology 28 (6), 443-447, 1992 and 30

(2). 145-153, 1992.

 

Bronaugh,et al. 28 (5), 369-373, 1990. Kosmet Database reports from

IFSCC (International Federation of the Societies of Cosmetic Chemists),

National Societies of Cosmetic Chemists, technical publications from

professional associations; Delaport House, Luton, Bedfordshire, UK.

 

Lee, Gibson, & Zimmer, Food and Chemical Toxicology, (28), 27-28. 1985 &

(6), 1990.

 

Watt, M. Plant Aromatics Data & Reference Manual on Essential Oils and

Aromatic Plant Extracts. 1994; and personal communications.

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I believe that eo's enter the body through the skin.

Try rubbing a clove of garlic on the bottom of your foot and then smelling

your breath just 10 minutes later!

Yes, I'm sure we can discuss this MORE. Can't manage more at present but will

join in if and when.

Regards

Ann - Scotland

 

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  • 2 weeks later...

In a message dated 1/14/02 4:21:23 PM, writes:

 

<<My husband is allergic to asprin and most OTC cold medications, he

 

suffers from back pain, so I gave him a massage using lavender,

 

ylang ylang and geranium rose in a Grapeseed base, he felt tremedous

 

relief, but I was surprised when he asked later if I could put a

 

bowl of the oil I was using where he could smell it - I smell it as

 

I was applying it but apparently on the table with his head faced

 

down he could not smell it. Just my observation as I said I am not a

 

expert but I do think that you can get the benefits from skin

 

absorbtion, given my husband has a very low pain tolerance and is a

 

big baby when it comes to pain, if he did not feel better he would

 

definetly not be shy in telling me

 

Just my 2cents

 

Emryldgea>>

 

But, his asking to have it to smell supports those who say that in such

situations (massage) that it is what is inhaled that is having the effect?

Shivani

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I understand what you are saying and agree that the scent also has

an effect, I probably did not explain it correctly but it was after

the massage, he was giving me feedback - saying he would like to

smell the blend, he had relief from his backpain without smelling

the oil.

I always ask and record any reaction people have when I try a new

blend.

 

Emryldgea

 

 

-- In , SArjuna@a... wrote:

 

But, his asking to have it to smell supports those who say that

in such

> situations (massage) that it is what is inhaled that is having the

effect?

> Shivani

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Hi Emryldgea, all...

 

Good for you (recording it all, so do I and it really helps to have it to

look back on...), and I've had the same experience where Mark couldn't smell

what I was massaging on him, but it worked....... heck, when he smells it, he

falls asleep! LOL :) Yummy........zzzzzzzzzzzzzzzzzzzzz...........

 

Hugs,

 

Marilyn

 

emryldgea wrote:

 

> I understand what you are saying and agree that the scent also has

> an effect, I probably did not explain it correctly but it was after

> the massage, he was giving me feedback - saying he would like to

> smell the blend, he had relief from his backpain without smelling

> the oil.

> I always ask and record any reaction people have when I try a new

> blend.

>

> Emryldgea

>

> -- In , SArjuna@a... wrote:

>

> But, his asking to have it to smell supports those who say that

> in such

> > situations (massage) that it is what is inhaled that is having the

> effect?

> > Shivani

>

>

> How To Make Rose Petal Jam - Step By Step Instructions

> http://www.av-at.com/stuff/rosejam.html

>

>

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