blood cells squeez out between endothelial cells?

October 2, 2003

In a message dated 10/2/2003 5:19:38 PM Eastern Daylight Time,

susegmen writes:

white blood cells leave the circulatory system by squeezing out between

endothelial cells

This is interesting. Which endothelial cells do they squeeze out form?

Where do they go?

Thanks,

Chris

October 3, 2003

Neutrophils are called PMNs when they exit the blood stream ... usually at an

injury site. Monocytes are called macrophages when they exit. They are normal

occupants of peripheral tissues all over the body. Macrophages occupy the

lungs, the skin (Langerhans cells), kidney (Kupfer cells), the spleen, and

through the loose connective tissues of the body between skin and muscles, etc.

Basophils are called mast cells when they exit the bloodstream. They play roles

inflammation and allergies as they secrete histamine. Lymphcytes (B and T

cells) are normal occupants of lymphatic tissues such as lymph nodes, tonsils,

Peyer's patches in the small intestine and also throughout the loose connective

tissues. Lymphocytes and macrophages act together in peripheral tissues to

mount immune responses.

Emmanuel Segmen

Merritt College