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> Heinz bodies are a blood problem that lead to anemia and can be life

>threatening. In dogs and cat they can be caused by onions and garlic.

Cats are >particularly susceptible. Here are some of the pages, excerpts

and links. There >is more at the individual sites.

 

One should also be concerned about the detrimental effect on gut flora IMO:

 

1: Folia Microbiol (Praha) 1984;29(4):348-52 Related Articles, Links

 

A comparative study of raw garlic extract and tetracycline on caecal

microflora and serum proteins of albino rats.

 

Shashikanth KN, Basappa SC, Sreenivasa Murthy V.

 

Studies conducted on the comparative action of raw garlic extract and

tetracycline hydrochloride on equal concentrations showed the raw garlic

extract to be a more potent antimicrobial agent than tetracycline. The

reversion to normalcy of caecal microflora and serum proteins after the

withdrawal of test materials indicated an inverse relation between

intestinal microflora and serum globulins.

 

PMID: 6479758 [PubMed - indexed for MEDLINE]

 

 

1: Appl Environ Microbiol 2001 Jan;67(1):475-80 Related Articles, Links

 

Antimicrobial properties of garlic oil against human enteric bacteria:

evaluation of methodologies and comparisons with garlic oil sulfides and

garlic powder.

 

Ross ZM, O'Gara EA, Hill DJ, Sleightholme HV, Maslin DJ.

St. George's University, St. George's, Grenada, West Indies, United Kingdom.

 

The antimicrobial effects of aqueous garlic extracts are well established

but those of garlic oil (GO) are little known. Methodologies for estimating

the antimicrobial activity of GO were assessed and GO, GO sulfide

constituents, and garlic powder (GP) were compared in tests against human

enteric bacteria. Test methodologies were identified as capable of producing

underestimates of GO activity. Antimicrobial activity was greater in media

lacking tryptone or cysteine, suggesting that, as for allicin, GO effects

may involve sulfhydryl reactivity. All bacteria tested, which included both

gram-negative and -positive bacteria and pathogenic forms, were susceptible

to garlic materials. (snip)

 

PMID: 6366484 [PubMed - indexed for MEDLINE]

 

 

Antimicrobial properties of allicin from garlic.

 

Ankri S, Mirelman D.

 

Department of Biological Chemistry, Weizmann Institute of Science, Rehovot

76100, Israel.

 

Allicin, one of the active principles of freshly crushed garlic homogenates,

has a variety of antimicrobial activities. Allicin in its pure form was

found to exhibit i) antibacterial activity against a wide range of

Gram-negative and Gram-positive bacteria, including multidrug-resistant

enterotoxicogenic strains of Escherichia coli; ii) antifungal activity,

particularly against Candida albicans; iii) antiparasitic activity,

including some major human intestinal protozoan parasites such as Entamoeba

histolytica and Giardia lamblia; and iv) antiviral activity. The main

antimicrobial effect of allicin is due to its chemical reaction with thiol

groups of various enzymes, e.g. alcohol dehydrogenase, thioredoxin

reductase, and RNA polymerase, which can affect essential metabolism of

cysteine proteinase activity involved in the virulence of E. histolytica.

 

PMID: 10594976 [PubMed - indexed for MEDLINE]

 

1: Int J Antimicrob Agents 1999 Aug;12(3):257-62 Related Articles, Links

 

Antimicrobial activity of spices.

 

Arora DS, Kaur J.

 

Department of Microbiology, Guru Nanak Dev University, Amritsar, India.

 

Spices have been shown to possess medicinal value, in particular,

antimicrobial activity. This study compares the sensitivity of some human

pathogenic bacteria and yeasts to various spice extracts and commonly

employed chemotherapeutic substances. Of the different spices tested only

garlic and clove were found to possess antimicrobial activity. The

bactericidal effect of garlic extract was apparent within 1 h of incubation

and 93% killing of Staphylococcus epidermidis and Salmonella typhi was

achieved within 3 h. Yeasts were totally killed in 1 h by garlic extract but

in 5 h with clove. Some bacteria showing resistance to certain antibiotics

were sensitive to extracts of both garlic and clove. Greater anti-candidal

activity was shown by garlic than by nystatin. Spices might have a great

potential to be used as antimicrobial agents.

 

PMID: 10461845 [PubMed - indexed for MEDLINE]

 

Jackie

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