SOME NOTES ON NIACINAMIDE THERAPY FOR ARTHRITIS

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SOME NOTES ON

NIACINAMIDE THERAPY FOR ARTHRITIS

by William Kaufman, M.D., Ph.D.

(Reprinted with the kind permission of Charlotte Kaufman)

 

The (more frequent) 250 mg dose of niacinamide is 40 to

50 % more

effective in the treatment of arthritis than the (less

frequent) 500 mg.

dose. As an illustration, see the reprint of my Tom Spies

Memorial

Lecture: Niacinamide, a Most Neglected Vitamin. This

illustrative case

history begins on page 17 column 2 and continues on page

18 column 2.

 

Do not use hard gelatin capsules containing 250 mg

niacinamide because

they do not deliver niacinamide as efficiently as 250mg

niacinamide in

thin gelatin capsules in the treatment of joint

dysfunction (arthritis).

 

In my paper in J. Amer Geriat. Society, 1955 3:927-936 I

noted that

niacinamide (alone or combined with other vitamins) in a

thousand

patient-years of use has caused no adverse side effects.

 

Some brands of niacinamide on the market today contains

excipients that

act as preservatives, probably meant to prolong shelf

life. Some patients

have severe adverse reactions to these preparations while

most do not

experience any ill effects.

 

Niacinamide has un-gated entrance to the central nervous

system. It has a

strong affinity for the central nervous system's

benzodiazepine receptors

and causes a pleasant calmative effect. In addition, it

improves central

nervous system function in the kinds of central nervous

symptom

impairments noted in my 1943 book, starting on page 3.

 

Please keep in mind niacinamide is a systemic therapeutic

agent. It

measurably improves joint mobility, muscle strength,

decreases

fatigability. It increases maximal muscle working

capacity, reduces or

completely eliminates arthritic joint pain. Niacinamide

heals broken

strands of DNA and improves many kinds of CNS

functioning.

 

Some joints are so injured by the arthritic process that

no amount of

niacinamide therapy will cause improvement in joint

mobility, but it

takes three months of niacinamide therapy before you can

conclude this,

since some joints are slow to heal.

 

WILLIAM KAUFMAN, PhD, MD

January 13,1998