Guest guest Posted April 7, 2005 Report Share Posted April 7, 2005 " HSI - Jenny Thompson " <HSIResearch HSI e-Alert - Answering the Call Thu, 07 Apr 2005 06:59:00 -0500 HSI e-Alert - Answering the Call Health Sciences Institute e-Alert **************************************************** April 07, 2005 Dear Reader, A friend of mine who grew up in Montpelier, Vermont, recalls a time when emergencies in the small capital city were announced by blasts on a powerful horn near the center of town. Back then, the local volunteer firefighters knew the coded series of blasts to listen for that signaled the need to drop everything and report to the fire house. In a sense, this is what happens in your body after surgery; a series of complex immune and inflammatory changes send out the signal that special resources are urgently needed. Time to send in the immunonutrients. Specifically, there are five nutrients that have been shown to improve immune system function after surgery, according to a special report in the British Medical Journal (BMJ). The overall result: fewer infections and shorter hospital stays. ----------- Multi-taskers ----------- You don't have to be in need of surgery to reap the benefits of immunonutrients, which also provide natural defenses against common viral and bacterial infections. So with some helpful insights from HSI Panelist Allan Spreen, M.D., we'll take a look at the five immunonutrients featured in the BMJ report, along with notes on the best sources of each. I'll begin with the nutrient that needs no introduction to HSI members: omega-3 fatty acids. We've written about this key nutrient so often in both the Members Alert and the e-Alert that I'm not going to delve into this very familiar information again here. (For a quick overview of the benefits of omega-3s, check the e-Alert archives on the HSI web site for " Fish in Fashion " 4/10/02.) And in the recent e-Alert " Sensitive Side " (3/30/05), I told you about L-arginine, a remarkable amino acid that's known to play a role in a number of important functions, including: blood vessel dilation, reduction of inflammation, thymus gland regulation and repair of skin and connective tissue. The other three immunonutrients are L-glutamine, branched chain amino acids, and nucleotides. After looking over this list, Dr. Spreen told me that even though Europeans tend to be less biased than the U. S. medical establishment, he was impressed that the BMJ spoke so highly of these healing nutrients. ----------- The antioxidant's friend ----------- The BMJ report highlighted the successes of using post-surgical L-glutamine (or simply " glutamine " ) intravenously to combat toxins and reduce the incidence of pneumonia. Dr. Spreen said, " I'm STUNNED at the comments (and progress) made with intravenous glutamine. I had no idea they'd gone so far at trying such things. It's pretty detailed when you're putting it in an IV and fixing up intestinal mucosae and stimulating the immune system. " Dr. Spreen also explained this additional benefit of L-glutamine: " It seems the brain uses glutamic acid almost as well as glucose for energy, and with less stress in doing so. The problem is, it doesn't cross the blood-brain barrier into the brain directly. However, glutamine DOES cross, and then the brain can convert it to the utilizable form and burn it. It makes sense that easy-energy fuel for the body's processes would make everything work better. " L-glutamine is one of the precursors of the highly effective antioxidant glutathione, which I've written about many times. There are a number of good dietary sources of L-glutamine, including meats, fresh fruits and vegetables. L-glutamine supplements are also widely available. ----------- The repairman ----------- Dr. Spreen tells me that branched chain amino acids (BCAAs) are apparently the easiest form of protein for the body to use for repair, and that's why this nutrient is popular with many body builders. " BCAAs are readily available for incorporating into new proteins, both stuctural and enzymatic. " The three BCAAs (leucine, valine, and isoleucine) are essential amino acids, which are also precursors of glutamine. Without BCCAs in our diets, we literally couldn't live. About BCCAs, Dr. Spreen says, " I've always felt that anything that makes it easier for the body to 'do its thing' is immunologically beneficial. If it has easy access to energy, readily available components for fixing whatever's damaged, and ways to move the body's biochemical processes around without having to worry about 'rationing' what's available, that HAS to make it easier to go out and eat invading organisms and fix whatever's broken. " BCAAs are available in supplement form, but are easily obtained from meat, whey protein, egg protein and other dairy products. ----------- Down in the DNA ----------- As for our last of the big five immunonutrients - nucleotides - Dr. Spreen says they've been mentioned in articles for years as immune system enhancers, but he's never had the occasion to use them. Nucleotides (the basic unit of nucleic acids) are the building blocks of DNA, and they help make cell division possible. When the immune system is under stress, new cells are needed to help fight infection. White blood cells, bone marrow cells, and the mucous cells of the intestine all require sources of nucleotides. Breast milk is perhaps the richest source of nucleotides. Formula-fed infants are generally more prone to infection than breast-fed children, and researchers believe that nucleotides are primarily responsible for this difference. Organ meats such as liver and kidney are rich in nucleotides, as are legumes and seafood. Nucleotides and nucleic acids supplements are also available. ----------- Food for thought ----------- One final note from Dr. Spreen: " If amino acid supplements (which can be expensive) are taken with protein foods, the protein receptor sites are flooded with competition from the protein in foods. So if you're trying to get a predominance of one amino acid for some reason (L-glutamine for energy, arginine for growth hormone production, etc.) you'd be wasting money to take them with other proteins. " **************************************************** ....and another thing An article published by UPI Science News reports on two studies that tell us, first of all, what HSI members already know: antioxidants are good for us. But the article also contains useful information on what foods provide the greatest benefit. Specifically, the antioxidants in blueberries may be effective in retarding the onset of Alzheimer's disease, and the antioxidants in honey may prevent the oxidation of LDL cholesterol - the so-called bad cholesterol. " Typically, the more color in food, the better it is for you, " Nicki Engeseth, assistant professor of food chemistry at the University of Illinois, and the leader of the honey research team, told UPI. In fact, Engeseth's cholesterol research shows that buckwheat honey - a very dark grade of honey - has a much higher level of antioxidants than lighter honeys. As for blueberries, researchers at Tufts University concluded that a chemical in blueberries called anthocyanis is the active ingredient responsible for protecting brain cells. Anthocyanis is also the chemical that gives blueberries their extremely dark color. Interestingly, a colleague reminded me that the same is true of wines. So when drinking red wine solely for medicinal purposes (as I'm sure most of you do), you might choose a pinot noir or a zinfandel for maximum benefit. To Your Good Health, Jenny Thompson Health Sciences Institute **************************************************** Sources: " Immunonutrition May have Beneficial Effects in Surgical Patients " British Medical Journal, Vol. 327, 7/19/03, bmj.com " Commonly Used Immunonutrients and Their Key Functions " British Medical Journal, online extra, 7/19/03, bmj.com " Immune-Boosting Nutrients Beneficial After Surgery " Dr. Joseph Mercola, 8/9/03, mercola.com " Blueberries, Honey Help Brain, Heart " UPI Science News, 8/19/02, upi.com ******** Quote Link to comment Share on other sites More sharing options...
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