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Magnetic resonance imaging

http://www.answers.com/topic/magnetic-resonance-imaging-1 & method=6

 

A special radiology technique designed to image internal structures of the body

using magnetism, radio waves, and a computer to produce the images of body

structures. In magnetic resonance imaging (MRI), the scanner is a tube

surrounded by a giant circular magnet. The patient is placed on a moveable bed

that is inserted into the magnet. The magnet creates a strong magnetic field

that aligns the protons of hydrogen atoms, which are then exposed to a beam of

radio waves.

 

This spins the various protons of the body, and they produce a faint signal that

is detected by the receiver portion of the MRI scanner.

 

A computer processes the receiver information, and an image is produced. The

image and resolution is quite detailed and can detect tiny changes of structures

within the body, particularly in the soft tissue, brain and spinal cord, abdomen

and joints.

 

An MRI is painless and has the advantage of avoiding x-ray radiation exposure.

There are no known risks of an MRI. The benefits of an MRI relate to its precise

accuracy in detecting structural abnormalities of the body. Patients with heart

pacemakers, metal implants, or metal chips or clips in or around the eyes cannot

be scanned with MRI because of the effect of the magnet. Metallic chips,

materials, surgical clips, or foreign material (artificial joints, metallic bone

plates, or prosthetic devices, etc.) can significantly distort the images

obtained by the MRI scanner.

 

Similarly, patients with artificial heart valves, metallic ear implants, bullet

fragments, and chemotherapy or insulin pumps should also not have an MRI.

Claustrophobia can be a problem. For an MRI, patients lie in a closed area

inside the magnetic tube. Some patients experience a feeling of claustrophobia.

 

In 2003 the Nobel Prize in Physiology or Medicine was awarded to the American

Paul C. Lauterbur (1929-) and the Briton Sir Peter Mansfield (1933-) " for their

discoveries concerning magnetic resonance imaging. " The presentation speechs was

given by Professor Hans Ringertz, Chairman, The Nobel Assembly at Karolinska

Institutet, who recounted the history of MRI, as follows.

 

Felix Block and Edward Mills Purcell first demonstrated the physical phenomenon

of nuclear magnetic resonance in 1946. These discoveries were awarded a Nobel

Prize in Physics in 1952.

 

Magnetic resonance occurs in magnetic fields between atomic nuclei and

electromagnetic waves of radio frequencies.

Atomic nuclei have a magnetic moment and in the magnetic field, their spin

depends on the strength of the field. The direction of magnetization resulting

from the magnetic moments can change.

 

This happens when the nuclei are in resonance with radio waves of the same

frequency as the frequency of their own rotation.

 

In the same way the nuclei can send back radio waves, when there is a change in

the direction of the magnetic moment.

 

 

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Also,

CT is a very low-risk procedure.

 

* You will be exposed to radiation when undergoing a CT. However, it

is a safe level.

 

* The biggest potential risk is if you need to get a contrast (also

called dye) injection. This can help distinguish normal tissues from

abnormal tissues. It also helps to distinguish blood vessels from other

structures such as lymph nodes.

 

* Like any medication, some people can have a bad reaction to the

contrast. The chance of a fatal reaction to the contrast is about 1 in

100,000. Those at increased risk may require special pretreatment and

should have the test in a hospital setting. Anyone who has had a prior

contrast reaction or severe allergic reaction to other medications, has

asthma or emphysema, or has severe heart disease is at increased risk

for a contrast reaction and is referred to a hospital x-ray department

for the exam.

 

* Any time an injection is done into a vein, there is a risk of the

contrast leaking outside of the vein under the skin. If a large amount

of contrast leaks under the skin, in rare cases, this can cause the skin

to break down.

 

 

CONTRAST MATERIALS ARE DRUGS

 

All contrast agents used in radiography are potentially harmful and

should be used knowledgeably. Contrast materials must be considered

drugs because they are NOT biologically inert, pharmacologically

inactive, and efficiently and innocuously excretable. [5] " From a

purely pharmacologic point of view, contrast media should be regarded as

among the safest of all intravascular drugs. Nevertheless, the high

utilization rate of these substances must invariably be associated with

significant numbers of reactions even at very low reaction incidence. "

[16, p. 171]

 

RADIOGRAPHERS SHOULD BE ALERT TO IMPLICATIONS OF USING CONTRAST MATERIALS

 

Radiographers and physicians involved in contrast procedures should

frequently review product package inserts for the specific contrast used

during a procedure. The appropriate contrast material for a procedure

depends on the area to be examined, the patient's age, weight, general

physical condition, state of health, and the route by which it should be

eliminated after the procedure.[11] The latest nonionic iodine contrast

agents have low osmolality and demonstrate significant risk reduction

for patients. These new contrast materials require us to re-evaluate

all contrast procedures.

 

While radiographers do not independently select the type of contrast for

any particular patient's radiographic exam, the nature of the procedures

places most radiographers in immediate and continuous contact with

patients after they receive contrast materials. Radiographers are the

first to recognize and respond to a patient's reaction to contrast

material. Radiographers have input into departmental protocol and

purchasing. For these reasons as well as professional interest,

radiographers should often review current information about contrast

materials.

 

Some patients receiving contrast studies deserve special consideration.

As with other ionizing radiographic examinations, the radiographer

should confirm that the patient is not pregnant before beginning a

contrast procedure. Because of inconclusive human data, nursing mothers

should convert to bottle feedings for 24 hours following iohexol (iodine

contrast) injection.[12]

 

 

PURPOSE OF CONTRAST MATERIALS

 

* The purpose of contrast materials is to increase differential

attenuation between a soft tissue structure and surrounding tissue.

* The purpose of double contrast procedures is to coat the surfaces

of a body structure with positive contrast and fill the lumen with

negative contrast.

 

POSITIVE AND NEGATIVE CONTRAST MATERIALS

 

Negative Contrast Materials

 

Negative contrasts appear dark on the radiographic image because they

decrease the tissue density. X-Ray photons have little attenuation as

they pass through an area filled with air so more photons reach the

film. This creates a " dark " area on the radiograph. Room air is most

often used as a negative contrast material because of the increased risk

of emboli when using oxygen and the tendency of carbon dioxide to

decrease local tissue pH. Negative contrast may be used alone

(example: myelograms, arthrograms) or in combination with a positive

contrast material (examples: upper GI, BE with air). When a positive

and a negative contrast material are used together, it is called a

" double contrast " study.

 

 

Positive Contrast Materials

 

Positive contrasts appear white or light on the radiographic image

because they increase the tissue density. X-Ray photons are attenuated

by the contrast material's molecules, casting a " shadow " on the film to

represent areas filled with the contrast material. The linear

attenuation coefficient of a contrast material is proportional to the mg

of iodine or barium per mL of solution.

Examples of positive contrast materials include barium sulfate and

iodinated contrast materials.

 

 

PATIENT PREPS

 

Patient prep information should include descriptions of the preparations

necessary before the procedure, purpose of the test, mechanics of the

procedure, patient's role, approximate time required, explanation of

equipment, and any requirements following the procedure. In some

states, patient prep may also include a consent form for iodine contrast

procedures.

 

Radiographers or receptionists should give clear directions to

outpatients in a variety of formats. Talking slowly with the patient,

giving them written directions to take home, and having the patient

repeat the instructions are ways to be sure the patient understands.

Nurses are usually responsible for prepping inpatients.

 

Patient preps before contrast procedures have several functions:

 

* clean GI tract for better visualization of structures

* decrease chance of nausea / vomiting and subsequent aspiration

* allow more concentration of contrast material in body part

 

Examples of patient prep for GI procedures include[3]:

 

 

* special diets

o low residue foods for several days before the procedure

o increased water and transparent liquids 24 hours before the

procedure, to promote bowel cleansing and decrease chance of dehydration

o NPO 8 to 10 hours before the procedure

o chewing gum and smoking are discouraged because they

stimulate gastric secretions which could dilute the contrast material

and increase the chance of aspiration. Chewing gum and smoking also

increase the amount of air in the GI tract.

* cathartics

o laxatives

o may be oral or suppositories

o should encourage patients to increase intake of fluids to

prevent dehydration

* enemas

o tap water or soapy water

* pre-meds

o to reduce anxiety, anesthetize area, reduce peristalsis,

fill area with contrast, etc.

 

 

 

 

HOCM v. LOCM

 

According to McClennan [2] low osmolality nonionic compounds should

replace high osmolality contrast materials because of their reduced

osmolality, reduced chemotoxicity, and increased hydrophilicity.

 

The Katayama data show a conventional contrast adverse reaction rate of

12.66% compared to 3.13% for nonionic contrast agents.[5] These data

show dramatic reductions in incidences of nausea, heat sensation,

vomiting, itching, urticaria, flushing, vascular pain, hoarseness,

sneezing, coughing, chest pain, abdominal pain, palpitation, facial

edema, rigor/shiver, dyspnea, and sudden drops in blood pressure.

 

" High osmolality and viscosity are the major characteristics of

water-soluble contrast media that are responsible for the hemodynamic,

cardiac, and subjective effects ... These effects include vasodilation,

heat, pain, a variety of hemodynamic effects, and an osmotic diuresis. "

[16, p. 2]

These actions cause patient dehydration.

 

 

PHYSIOLOGIC EFFECTS OF IODINATED CONTRASTS [1, 8, 15]

 

Neurologic System

 

 

During IV injections, the blood-brain barrier usually prevents

contrast material from contacting delicate nerve cells. During

intrathecal injection, there is no barrier to protect the nerve cells.

Because the central nervous system is sensitive to changes in electrical

potential of cell membranes, and ionic contrasts can change electric

potentials, ionic contrasts can cause seizures if introduced into the

subarachnoid space around the brain. Radiographers and physicians had

to depend on gravity and patient position to keep the contrast in the

spinal canal and away from the subarachnoid space around the brain.

Nonionics do not cause a change in electric potential. Most facilities

no longer use any ionics for myelography or intrathecal injections.[15]

 

Patient conditions which affect the blood-brain barriers, like brain

metastases, place the patient at higher risk for seizures. Seizure

rates after IV contrast are rare in the general population (0.01%), but

are significantly higher in patients with brain metastases (6 - 19%).

[16, p.16]

 

Effects reported on the neurologic system include headache, vertigo,

photomas, taste perversion, anxiety, blurred vision, motor/speech

dysfunction, paresthesia, somnolence, stiff neck, hemiparesis, syncope,

and nystagmus.[12] Unconsciousness and rarely coma and convulsions are

described in other literature. Reports of transient blindness usually

resolve completely in a few moments, but on occasion last 48 hours.

 

 

IODINATED CONTRAST REACTIONS

 

Generalized Contrast Reactions [3, 11, 16]

Comparisons between studies are difficult because there are no universal

symptom categories for minor or mild, moderate, and severe or major

contrast reactions. The following is a compilation of several resources.

 

a. Minor Reaction - occur in 5% of injections [16]

Symptoms include:

- metallic taste in the mouth

- warm flushed feeling

- nausea and vomiting

- sweating

- light-headedness

- perioral dysesthesia

- pain at injection site

- urticaria

- headache

- salivary gland swelling

- few, scattered hives

Radiographer Response:

- reassure patient

- make patient comfortable with cool cloth

- avoid aspiration

- some references suggest interrupting the contrast injection if

flushing or nausea occurs[16]

- alert MD of symptoms

- MD may give Compazine for nausea

- MD may give Benadryl for hives

 

 

 

b. Moderate Reaction - occur in 0.022% of injections

Symptoms include:

- pain at the injection site

- urticaria

- hives

- persistent and intense minor symptoms

- dyspnea

- hypotension

- chest pain

Radiographer Response:

- reassure patient

- make patient comfortable

- alert MD of symptoms

- MD may give Compazine for nausea

- MD may give Benadryl for hives

- MD may give Tagamet, Zantac, or cimetidine for urticaria

 

c. Major Reaction - occur in 0.0025% of injections

Early symptoms include [11]:

- itching at injection site

- sneezing, coughing

- bronchospasm

- apprehensiveness

- persistent and intense minor symptoms

- nausea, vomiting

- paresthesia

- diarrhea

Later symptoms include [3]:

- edema of face, hands, and other body parts

- subclinical pulmonary emboli

- choking, wheezing, dyspnea, cyanosis, bronchospasm

- decreasing blood pressure, bradycardia, weak rapid pulse, shock

- pulmonary edema

- cardiac arrhythmia, MI

- dilated pupils

- convulsions

- paralysis

- renal failure

- coma

- death

Radiographer Response:

- recognize need for action, stop procedure

- know how to call for help and how to

call a code

- monitor vital signs

- keep code cart accessible and updated

- know location of emergency drugs and supplies

- know location and how to use oxygen

- know and begin CPR if necessary

- assist patient during seizure activity if necessary

- MD may give oxygen, inhalation therapy of Alupent, Brethaire, or

Proventil for

bronchospasm

- MD may give epinephrine for bronchospasm

- MD may give IV fluids (for shock), Solu-Cortef, Solu-Medrol

(antihistamines and

corticosteroids are useless initially - hour lapse), dopamine (for

tachycardia),

atropine (for bradycardia), diazepam (Valium), etc.

 

Nausea and Vomiting

The most likely reason for nausea and vomiting is stimulation of the

chemoreceptor trigger zone which controls the vomiting center and is

located in the floor of the fourth ventricle. This area has no

blood-brain barrier. Nausea and vomiting have been substantially

reduced when using nonionics.[15, 16]

 

 

 

 

 

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