Marijuana Ingredient May Help Alzheimer's

February 23, 2005

Wednesday, February 23, 2005

By Miranda HittiNew clues about Alzheimer’s disease (search) have emerged

from a Spanish study of marijuana. The drug’s active ingredients —

cannabinoids (search) — help prevent brain problems seen in Alzheimer’s, say

the scientists.

There is no cure for Alzheimer’s disease, which progressively damages brain

areas involved in memory, judgment, language and behavior. Alzheimer’s

disease is the most common form of mental decline, or dementia (search), in

older adults.

The new study didn’t test cannabinoids on people living with Alzheimer’s

disease. Instead, the researchers focused on human brain tissue samples and

conducted cannabinoid experiments on rats.

The findings showed that “cannabinoids work both to prevent inflammation and

to protect the brain,” says researcher Maria de Ceballos in a news release.

That “may set the stage for [cannabinoids’] use as a therapeutic approach

for [Alzheimer’s disease].”

A staff member at Madrid’s Cajal Institute, de Ceballos conducted the study

with colleagues from nearby Complutense University. Their results appear in

the Feb. 23 edition of The Journal of Neuroscience.

Marijuana, Alzheimer’s Disease, and the Human Brain

The researchers studied human brain tissue samples, some of which were from

deceased Alzheimer’s patients and some from normal brain tissue.

The typical features seen in the brain tissue of Alzheimer's disease are

called plaques. Plaques are protein clumps that are seen outside brain cells

and they have been shown to activate inflammation seen in brain tissue of

Alzheimer's disease patients.

Besides the typical plaques seen with Alzheimer’s disease, the brain tissues

taken from Alzheimer’s patients also had many fewer cannabinoid receptors.

Significant changes in the location, expression, and function of cannabinoid

receptors may play a role in Alzheimer’s disease, write the researchers.

That could mean that the patients had lost the capacity to experience

cannabinoids’ protective effects, says the news release.

Marijuana and Alzheimer’s Mental Decline

The researchers also injected rats with a protein called beta-amyloid

(search), which gave the rats an Alzheimer’s-like brain condition.

Some of the same rats were also injected with a cannabinoid. For comparison,

other rats got injections of an unrelated protein along with beta-amyloid.

After two months, the rats were tested for learning, memory, and mental

functions. The researchers tried to train them to find a platform in a tank

of water. The rats had two minutes to find the platform. If they failed, the

researchers briefly put the rats on the platform. Four times a day for five

days, the rats practiced.

By the fifth day, the rats that received the cannabinoid injections were

able to find the platform on their own. Those that didn’t get the

cannabinoid injections didn’t learn to find the platform.

Another interesting result also surfaced. The cannabinoids completely

prevented activation of cells that trigger inflammation. These cells gather

near plaque and are believed to be involved in the development of

Alzheimer’s disease.

“Our results indicate that cannabinoid receptors are important in the

pathology of Alzheimer’s disease and that cannabinoids succeed in preventing

the neurodegenerative process occurring in the disease,” write the

researchers in the journal.

They plan to focus future studies on a cannabinoid receptor that’s unrelated

to marijuana’s “high,” says the news release.

By Miranda Hitti, reviewed by Brunilda Nazario, MD

http://www.foxnews.com/story/0,2933,148518,00.html

lve,

Hempress

February 24, 2005

My son is still struggling to recover from marijuana

induced psychosis. He smoked marijuana fr a year. Its

not so easy and simple.

Ratan.

--- HAH <GaiaHemp wrote:

>

> Wednesday, February 23, 2005

> By Miranda HittiNew clues about Alzheimer’s disease

> (search) have emerged

> from a Spanish study of marijuana. The drug’s active

> ingredients —

> cannabinoids (search) — help prevent brain problems

> seen in Alzheimer’s, say

> the scientists.

> There is no cure for Alzheimer’s disease, which

> progressively damages brain

> areas involved in memory, judgment, language and

> behavior. Alzheimer’s

> disease is the most common form of mental decline,

> or dementia (search), in

> older adults.

> The new study didn’t test cannabinoids on people

> living with Alzheimer’s

> disease. Instead, the researchers focused on human

> brain tissue samples and

> conducted cannabinoid experiments on rats.

> The findings showed that “cannabinoids work both to

> prevent inflammation and

> to protect the brain,” says researcher Maria de

> Ceballos in a news release.

> That “may set the stage for [cannabinoids’] use as a

> therapeutic approach

> for [Alzheimer’s disease].”

> A staff member at Madrid’s Cajal Institute, de

> Ceballos conducted the study

> with colleagues from nearby Complutense University.

> Their results appear in

> the Feb. 23 edition of The Journal of Neuroscience.

> Marijuana, Alzheimer’s Disease, and the Human Brain

> The researchers studied human brain tissue samples,

> some of which were from

> deceased Alzheimer’s patients and some from normal

> brain tissue.

> The typical features seen in the brain tissue of

> Alzheimer's disease are

> called plaques. Plaques are protein clumps that are

> seen outside brain cells

> and they have been shown to activate inflammation

> seen in brain tissue of

> Alzheimer's disease patients.

> Besides the typical plaques seen with Alzheimer’s

> disease, the brain tissues

> taken from Alzheimer’s patients also had many fewer

> cannabinoid receptors.

> Significant changes in the location, expression, and

> function of cannabinoid

> receptors may play a role in Alzheimer’s disease,

> write the researchers.

> That could mean that the patients had lost the

> capacity to experience

> cannabinoids’ protective effects, says the news

> release.

> Marijuana and Alzheimer’s Mental Decline

> The researchers also injected rats with a protein

> called beta-amyloid

> (search), which gave the rats an Alzheimer’s-like

> brain condition.

> Some of the same rats were also injected with a

> cannabinoid. For comparison,

> other rats got injections of an unrelated protein

> along with beta-amyloid.

> After two months, the rats were tested for learning,

> memory, and mental

> functions. The researchers tried to train them to

> find a platform in a tank

> of water. The rats had two minutes to find the

> platform. If they failed, the

> researchers briefly put the rats on the platform.

> Four times a day for five

> days, the rats practiced.

> By the fifth day, the rats that received the

> cannabinoid injections were

> able to find the platform on their own. Those that

> didn’t get the

> cannabinoid injections didn’t learn to find the

> platform.

> Another interesting result also surfaced. The

> cannabinoids completely

> prevented activation of cells that trigger

> inflammation. These cells gather

> near plaque and are believed to be involved in the

> development of

> Alzheimer’s disease.

> “Our results indicate that cannabinoid receptors are

> important in the

> pathology of Alzheimer’s disease and that

> cannabinoids succeed in preventing

> the neurodegenerative process occurring in the

> disease,” write the

> researchers in the journal.

> They plan to focus future studies on a cannabinoid

> receptor that’s unrelated

> to marijuana’s “high,” says the news release.

> By Miranda Hitti, reviewed by Brunilda Nazario, MD

>

> http://www.foxnews.com/story/0,2933,148518,00.html

>

> lve,

> Hempress

>

> [Non-text portions of this message have been

> removed]

>

Mail - 250MB free storage. Do more. Manage less.

http://info.mail./mail_250

February 24, 2005

psychosis from marijuana? I never heard of that and tons of people who smoke it

C

psych doc <psych_58 wrote:

my son is still struggling to recover from marijuana

induced psychosis. He smoked marijuana fr a year. Its

not so easy and simple.

Ratan.

---

" Life is not holding a good hand; Life is playing a poor hand well. "

Danish proverb

Mail - Easier than ever with enhanced search. Learn more.

February 24, 2005

What happened to your son is what happened to some people who drank booze

when it was prohibited~ If it were legal, he may not have been able to get

it as easy anywhere on the streets and also if we had a better educational

system in America, like they have in Amsterdam, he could have said " Know " to

drugs before he decided to smoke something he had no idea he was actually

smoking~ For young people are taught what Cannabis is for in the UK, unlike

children in America are just taught to say " No " ratha than to " Know " what

all herbs all for~ Teenagers get the chance to make wise choices as to what

they are going to do with Cannibas and with that said, they normally choose

to not do it so blindy as American teenagers do~ Your son was self

medicating with something he had no bussiness messing with~ It was very easy

and simple for him to get it on the streets because it's unregulated~

Hempress

----

psych doc

02/24/05 10:51:36

Cc: ratans

Re: Marijuana Ingredient May Help

Alzheimer's

My son is still struggling to recover from marijuana

induced psychosis. He smoked marijuana fr a year. Its

not so easy and simple.

Ratan.

--- HAH <GaiaHemp wrote:

>

> Wednesday, February 23, 2005

> By Miranda HittiNew clues about Alzheimer’s disease

> (search) have emerged

> from a Spanish study of marijuana. The drug’s active

> ingredients —

> cannabinoids (search) — help prevent brain problems

> seen in Alzheimer’s, say

> the scientists.

> There is no cure for Alzheimer’s disease, which

> progressively damages brain

> areas involved in memory, judgment, language and

> behavior. Alzheimer’s

> disease is the most common form of mental decline,

> or dementia (search), in

> older adults.

> The new study didn’t test cannabinoids on people

> living with Alzheimer’s

> disease. Instead, the researchers focused on human

> brain tissue samples and

> conducted cannabinoid experiments on rats.

> The findings showed that “cannabinoids work both to

> prevent inflammation and

> to protect the brain,” says researcher Maria de

> Ceballos in a news release.

> That “may set the stage for [cannabinoids’] use as a

> therapeutic approach

> for [Alzheimer’s disease].”

> A staff member at Madrid’s Cajal Institute, de

> Ceballos conducted the study

> with colleagues from nearby Complutense University.

> Their results appear in

> the Feb. 23 edition of The Journal of Neuroscience.

> Marijuana, Alzheimer’s Disease, and the Human Brain

> The researchers studied human brain tissue samples,

> some of which were from

> deceased Alzheimer’s patients and some from normal

> brain tissue.

> The typical features seen in the brain tissue of

> Alzheimer's disease are

> called plaques. Plaques are protein clumps that are

> seen outside brain cells

> and they have been shown to activate inflammation

> seen in brain tissue of

> Alzheimer's disease patients.

> Besides the typical plaques seen with Alzheimer’s

> disease, the brain tissues

> taken from Alzheimer’s patients also had many fewer

> cannabinoid receptors.

> Significant changes in the location, expression, and

> function of cannabinoid

> receptors may play a role in Alzheimer’s disease,

> write the researchers.

> That could mean that the patients had lost the

> capacity to experience

> cannabinoids’ protective effects, says the news

> release.

> Marijuana and Alzheimer’s Mental Decline

> The researchers also injected rats with a protein

> called beta-amyloid

> (search), which gave the rats an Alzheimer’s-like

> brain condition.

> Some of the same rats were also injected with a

> cannabinoid. For comparison,

> other rats got injections of an unrelated protein

> along with beta-amyloid.

> After two months, the rats were tested for learning,

> memory, and mental

> functions. The researchers tried to train them to

> find a platform in a tank

> of water. The rats had two minutes to find the

> platform. If they failed, the

> researchers briefly put the rats on the platform.

> Four times a day for five

> days, the rats practiced.

> By the fifth day, the rats that received the

> cannabinoid injections were

> able to find the platform on their own. Those that

> didn’t get the

> cannabinoid injections didn’t learn to find the

> platform.

> Another interesting result also surfaced. The

> cannabinoids completely

> prevented activation of cells that trigger

> inflammation. These cells gather

> near plaque and are believed to be involved in the

> development of

> Alzheimer’s disease.

> “Our results indicate that cannabinoid receptors are

> important in the

> pathology of Alzheimer’s disease and that

> cannabinoids succeed in preventing

> the neurodegenerative process occurring in the

> disease,” write the

> researchers in the journal.

> They plan to focus future studies on a cannabinoid

> receptor that’s unrelated

> to marijuana’s “high,” says the news release.

> By Miranda Hitti, reviewed by Brunilda Nazario, MD

>

> http://www.foxnews.com/story/0,2933,148518,00.html

>

> lve,

> Hempress

>

> [Non-text portions of this message have been

> removed]

>

February 25, 2005

It is also an atypical reaction. There are many folks who use this herb

without incident.

What scares me is prescription drug use among kids. " Bars " (xanax)are common

in schools. Hydrocodone is widely used by even small children.

Younger and younger children are being prescribed antipsychotics like

risperdal, depakote, zoloft or Ritalin- that scares the hell out of me. They

are taught from birth to pop pills to feel good.

What I have found often is that when a teenager supposedly became psychotic

smoking marijuana, in fact, other drugs such as cocaine, alcohol, and/or

prescription meds were/or had been frequently used in the same period of

months.

HAH [GaiaHemp]

Thursday, February 24, 2005 3:22 PM