Zeranol, used in Beef Cattle, May Have Estrogenic Effect on Cancer

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Zeranol, used in beef cattle may have an estrogenic effect on growth of

cancerous cells in humans.

 

Residual amounts of the growth promoter Zeranol, used in beef cattle, may have

an estrogenic effect on the growth of normal and cancerous breast cells in

humans, Ohio researchers reported here at the " Era of Hope " Department of

Defense Breast Cancer Research Program Meeting.

 

http://www.annieappleseedproject.org/beefadcelsti.html

 

Dr. Young C. Lin, of the Comprehensive Cancer Center at Ohio State University,

in Columbus, tested serum, muscle tissue, and adipose tissue of cattle exposed

to Zeranol in culture with normal and cancerous human breast cells. They found

that serum, muscle extract, and adipose extract significantly elevated DNA

synthesis in normal cells, with adipose extract 2.5 times more potent than

muscle extract. Serum stimulated DNA synthesis in one of two cancerous cell

lines tested.

 

" The greater mitogenic potency of Zeranol-adipose extract versus Zeranol-meat

extract indicates the presence of other unidentified factors that may contribute

to effects on breast tissue, " Dr. Lin's team wrote in a meeting abstract. " The

lack of growth response in [one cancerous cell line] to Zeranol-serum indicates

dependence on estrogen receptors for mitogenic activity. "

 

" We must be very cautious at this stage, " Dr. Lin said. " At this point all we

have done is define that this factor is capable of mimicking estrogenic action

in gene amplification. In other words, these compounds act like estrogen at the

molecular level, but we have no reason to believe they are harmful to the

consumer. Diet studies need to be done in vivo, say in mice, to see how or if

the digestive process affects this chemical's action. "

 

" The FDA-approved levels of Zeranol are 150 ppb (parts per billion) for meat,

300 ppb for liver, 450 ppb for kidney and 600 ppb for fat tissue, " Dr. Lin told

Reuters Health. " Our laboratory samples had much lower concentrations, 0.34 ppb

in our 1% solution. " Dr. Lin again stressed that these were laboratory samples

developed and monitored under ideal conditions.

 

Ann's NOTE: Many of us suspect that hormones added to meat causes problems. This

study indicates that scientists can track this. The hormone appears to act as a

promoter of breast cell growth.

 

Thanks to Reuters Health (Downloaded from Oncolink-U of Penn).

_________________

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