Diets containing barley significantly reduce lipids in mildly hypercholesterolem

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Diets containing barley significantly reduce lipids in mildly

hypercholesterolemic men and women.

 

Behall KM, Scholfield DJ, Hallfrisch J.

http://www.docguide.com/dgc.nsf/us/Jo.Guest.887?opendocument & pp=2 &

 

 

Diet & Human Performance Laboratory, Beltsville Human Nutrition

Research Center, Agricultural Research Service, US Department of

Agriculture, Beltsville, MD.

 

BACKGROUND: Barley has high amounts of soluble fiber but is not

extensively consumed in the US diet.

 

OBJECTIVE: This study investigated whether consumption of barley

would reduce cardiovascular disease risk factors comparably with

that of other sources of soluble fiber.

 

DESIGN: Mildly hypercholesterolemic subjects (9 postmenopausal

women, 9 premenopausal women, and 7 men) consumed controlled

American Heart Association Step 1 diets for 17 wk. After a 2-wk

adaptation period, whole-grain foods containing 0, 3, or 6 g beta-

glucan/d from barley were included in the Step 1 diet menus. Diets

were consumed for 5 wk each and were fed in a Latin-square design.

Fasting blood samples were collected twice weekly.

 

RESULTS: Total cholesterol was significantly lower when the diet

contained 3 or 6 g beta-glucan/d from barley than when it contained

no beta-glucan; the greatest change occurred in the men and

postmenopausal women.

 

HDL and triacylglycerol concentrations did not differ with the 3

amounts of dietary beta-glucan. Large LDL and small VLDL fractions

and mean LDL particle size significantly decreased when whole grains

were incorporated into the 3 diets.

 

Large LDL and large and intermediate HDL fractions were

significantly higher, mean LDL particle size was significantly

greater, and intermediate VLDLfractions were significantly lower in

the postmenopausal women than

in the other 2 groups. A group-by-diet interaction effect was

observed on LDL fractions and small LDL particle size.

 

CONCLUSION: The addition of barley to a healthy diet may be

effective in lowering total and LDL cholesterol in both men and

women.

 

PMID: 15531664 [PubMed - in process]

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