Coronary-artery bypass surgery and the brain: persisting concerns.

[Guest guest]

" JoAnn Guest " <angelprincessjo

Sun Oct 24, 2004 11:20 pm

Coronary-artery bypass surgery and the brain: persisting

concerns

 

--

 

Lancet Neurol. 2002 Jun;1(2):119-25. Related Articles, Links

 

 

Coronary-artery bypass surgery and the brain: persisting concerns.

Newman SP, Harrison MJ.

Unit of Health Psychology, University College London Medical School,

Middlesex Hospital, Mortimer Street, London, UK. S.Newman

 

Mortality after coronary-artery bypass surgery (CABS) has fallen

steadily over recent years. Concern remains, however, about the

effect of this surgery on the brain.

 

The problem of brain damage after CABS is multifactorial, involving

microembolism, disturbed perfusion, metabolic derangement, and

inflammatory responses.

 

Microemboli numbers have been linked to the likelihood of

neuropsychological deterioration after surgery.

 

Risk factors for cerebral changes after CABS include older age,

gender, neurological disease, diabetes, and calcification of the

aorta.

 

These risk factors are important because, in comparison with the

early 1990s, patients undergoing CABS are now older and tend to have

a greater number of comorbid conditions.

 

Changes in surgical technique, such as the introduction of arterial-

line filters and membrane oxygenators, have led to a reduction of

both microemboli and neuropsychological disturbance. However, the

problem persists, prompting further studies on surgical technique

and neuroprotective strategies.

 

Publication Types:

Review

Review, Tutorial

 

PMID: 12849516 [PubMed - indexed for MEDLINE]

_________________

 

JoAnn Guest

mrsjoguest

DietaryTipsForHBP

www.geocities.com/mrsjoguest/Genes