Guest guest Posted October 20, 2004 Report Share Posted October 20, 2004 SSRI-Research@ Tue, 19 Oct 2004 18:07:11 -0400 Subject:Paxil: Effects of Paxil on man who murdered his employer This article states: " Dr. Ann Blake Tracy, an advocate against antidepressants like Prozac, Zoloft and Paxil, said there is no doubt Kinyon's use of antidepressants were behind the events of that day.. . Tracy, who has led a crusade against the antidepressants for more than a decade, has a different view, saying SSRIs " will produce impulsive murder and suicide. " " I think that's what we had in this case, " she said. " .. Paxil effects Date October 18, 2004 Justin Hill http://archive.harktheherald.com/archive_detail.php?archiveFile==./pubfiles/prv/\ archive/2004/October/18/LocalCity/50442.xml & start==0 & numPer= & keyword==kinyon & sectionSearch== & begindate==1%2F1%2F1997 & enddate=%2F31%2F2004 & a\ uthorSearch== & IncludeStories==1 & pubsection== & page== & IncludePages== & IncludeImages\ == & mode==allwords & archive_pubname==Heraldextra.com%0A%09%09%09 DAILY HERALD Life changed after Louis Darrell Kinyon started taking antidepressants. The family members who encompassed much of his world are only a small part of it now, and the comforts of home have been replaced by the discomforts of the Utah County Jail. Kinyon is an inmate now, awaiting his fate as prosecutors work to make him pay -- with his life -- for what they say is his role in the slaying of his boss earlier this year in Pleasant Grove. Several years ago, Kinyon, a father of four, led a different life. He coached baseball, basketball and any other sport his children played. He was a Scoutmaster. His family was always with him -- they went camping and four-wheeling. " He was a family man, " said his wife, Valorie Kinyon. But that life gradually began to change shortly before Kinyon's 40th birthday, when a doctor diagnosed Kinyon with fibromyalgia, a chronic pain illness that is sometimes accompanied by depression, and doctors prescribed an antidepressant. " At first, we noticed a big change in him, " Valorie Kinyon said. " He was more mellow. " Kinyon slept more -- his way of dealing with stress -- taking a nap at lunch every day. He also " got more belligerent, moodier, " his wife said. His family wouldn't know what would happen from minute to minute. " You never knew what was going to happen, " she said, adding later, " I figured Darrell was suicidal before. " Kinyon stopped coaching, camping and four-wheeling. Then came Monday, Feb. 2. That morning, Kinyon returned to work at the Provo River Water Users Association after serving a suspension his wife says was for his attitude over a computer. When Kinyon came back, he was fired, his wife said. According to police, Kinyon lost his temper during a morning meeting, knocking over a candy machine and pushing papers off desks. After he was fired, management confronted Kinyon about child pornography police say an employee discovered on Kinyon's company computer, Valorie Kinyon said. The state has since charged Kinyon with sexual exploitation of a minor -- a charge the defense says cannot be substantiated. Kinyon went home, two stop signs away, with his son who also worked at the Provo River Water Users Association,Valorie Kinyon said. Shortly thereafter, police say Kinyon returned to work with a 9 mm handgun, shooting and killing Kent Neil Griffith before turning the gun on himself. Dr. Ann Blake Tracy, an advocate against antidepressants like Prozac, Zoloft and Paxil, said there is no doubt Kinyon's use of antidepressants were behind the events of that day. " They're fitting the pattern, " Valorie Kinyon said. " How can you say it's not? " Kinyon's defense team is preparing to argue Kinyon suffered from extreme emotional distress caused by the use of Paxil and other drugs, Kinyon's attorney, Rhome Zabriskie, said last month. " We feel good about the direction it's going, " Zabriskie said. Paxil is one of the drugs in a class of antidepressants known as SSRIs, selective serotonin reuptake inhibitors, which also includes Zoloft, Prozac and Luvox. On Friday, the Food and Drug Administration sent letters to the makers of all antidepressants, directing them to add a " black box " warning describing the increased risk of suicidal thoughts and behavior in children and adolescents who have been given the drugs. The warning is the most serious in the labeling of prescription medications. The FDA is also developing a Patient Medication Guide to be given to patients who are taking the medication, advising them of the risk. The letters come seven months after the FDA asked makers of those drugs to include a warning label recommending close observation of adults and children treated with the antidepressants for depression and the emergence of suicidal thoughts and behavior. " Now you've got the Food and Drug Administration jumping on this bandwagon, " said Richard Southard, an attorney in New York City who has been a commentator on Fox News Live for several high-profile cases including the Lori Hacking murder. But, lawyers, including Southard, say employing a defense based on the use of Paxil and other SSRIs hasn't been successful on the whole. " It's unsuccessful right now because there aren't enough experts coming forward saying the link exists, " Southard said. There are cases, however, where defendants were exonerated by an involuntary intoxication defense based on the use of SSRIs -- one in California and one in Connecticut, said Andy Vickery, a Houston attorney who represents families of people he says have died as a result of violence and suicide caused by Prozac, Paxil and Zoloft. A number of studies indicate there is a link between SSRIs and violence among adults, said Edward Havas, an attorney in Salt Lake City who has handled four to six civil cases alleging that the use of SSRIs caused an aberrant reaction in Utah patients that led to a suicide or attempted suicide. Some people believe those studies, while others refute the data, he said. There is evidence the drugs cause a relatively small population to act in an atypical manner, Havas said. In the civil arena, Vickery obtained a $6.4 million jury verdict against GlaxoSmithKline, the British company that makes Paxil, in a case where a man on the drug killed his wife, daughter, granddaughter and himself. All of Havas' cases, which involved patients who were not suicidal but became so after they were on the drug for a relatively short amount of time, were settled, he said. The settlements are confidential. However, Dr. Michael Rhodes, program director for the Utah Valley family medicine residency at Utah Valley Regional Medical Center, said thousands of studies have been done on SSRIs and adults, including behavioral studies, involving tens of thousands of patients. There's been no difference between the placebo and treatment groups in terms of violence and suicide. " Most experts agree it doesn't cause any problems, " Rhodes said. He said he thinks the drugs are overused because " we know they're safe, and it's an easy fix. " But a definitive study on the topic has never been conducted, Rhodes said. All the studies so far have been retrospective, and to settle the issue definitively, someone would have to conduct a study looking into the future with two groups -- half using the drug and half using a placebo, he said. Tracy, who has led a crusade against the antidepressants for more than a decade, has a different view, saying SSRIs " will produce impulsive murder and suicide. " " I think that's what we had in this case, " she said. Tracy, who has testified at antidepressant-related court cases and before the FDA and congressional subcommittee members, took her analysis of the case one step further, saying Kinyon was misdiagnosed when his doctor told him he had fibromyalgia. As Tracy read a list of symptoms of hypoglycemia, an abnormally low level of sugar in the blood, Valorie Kinyon said her husband had many of them and gave examples. " I think he had low blood sugar, " Tracy said. " It runs in the family. He had all the symptoms. " Over a period of several years, Kinyon was prescribed many medications, including Prozac and Paxil. At the time of the incident at the Provo River Water Users building, Kinyon was taking Paxil as well as another antidepressant, trazodone, and several other drugs for other medical conditions: tramadol HCl, TOPROL-XL, Coumadin and CELEBREX. The benefits of Coumadin may be reduced when patients are taking the drug while on a trazodone treatment, according to the medical Web site AccessMedNet. Adjustments in dosage or periodic monitoring are recommended. Kinyon's use of antidepressants also caused a lesion on his brain, which was diagnosed in 2000, Tracy said. But, while this type of medical information has been unsuccessful as the basis of a criminal defense, Southard, the New York City attorney, predicted that will change in the future. As more people use the drugs, there's more opportunity to use the defense, and more debate about the safety of the drugs leads to additional studies, he said. " It's an unsuccessful defense, which I predict will become more and more successful as time goes on, " Southard said. º Justin Hill can be reached at 344-2548 or jhill. Learn more Dr. Ann Blake Tracy, an advocate against antidepressants like Prozac, Zoloft and Paxil, is scheduled to lecture at 7 p.m. Oct. 27 at the Total Health Institute in Lindon. For more information call 796-8114. Quote Link to comment Share on other sites More sharing options...
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