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> " HSI - Jenny Thompson "

> <HSIResearch

 

> Fat Chance

> Wed, 25 Aug 2004 08:46:11 -0400

>

> Fat Chance

>

> Health Sciences Institute e-Alert

>

> August 25, 2004

>

>

************************************************************

 

>

> Dear Reader,

>

> There may be an effective way to help manage your

> triglyceride levels

> without drugs, without dietary changes, without

> supplements, and –

> best of all – it's easy and it's free.

>

> Now don't run out of the room when I tell you what

> it is. Because a

> new study shows that the way you... exercise (there,

> I said it – still

> with me?) may make a significant difference in the

> way your body

> metabolizes triglycerides. And the good news is that

> the easy way to

> exercise may actually be the best way.

>

> That's right: Easy does it.

>

>

---------------------------

>

> Coming to terms

>

---------------------------

>

>

> Most HSI members are probably aware of the

> importance of keeping

> triglyceride levels down. Triglyceride is a

> naturally occurring

> organic compound in the blood that's derived from

> dietary fats. It's

> also created in the body from various energy sources

> such as

> carbohydrates. When triglyceride binds to carrier

> proteins,

> lipoproteins are created that may leave fat deposits

> in coronary

> arteries. In recent years, several studies have

> shown that high

> triglyceride levels sharply increase heart disease

> risk.

>

> Which brings us to postprandial lipemia; a condition

> that occurs when

> triglycerides, cholesterol and other blood fats rise

> after eating a

> meal that's extremely rich in fats and not balanced

> by other types of

> food. Heart disease risk may rise when postprandial

> lipemia becomes

> chronic.

>

> Because research has shown that exercise can help

> manage blood fat

> levels after eating, researchers at Southwest

> Missouri State

> University (SMSU) designed a study to examine the

> effects of two

> different types of exercise on postprandial lipemia.

>

>

>

---------------------------

>

> The milk shake test

>

---------------------------

>

>

> As reported in the current issue of the journal

> Medicine and Science

> in Sports and Exercise, researchers recruited 29

> " inactive " males and

> females in their mid-20s. Each subject participated

> in three phases of

> the trial. During one phase, a period of 30 minutes

> of continuous

> exercise was followed up with a high fat meal 12

> hours later. The

> " meal " consisted of a milk shake with heavy whipped

> cream that

> contained 1.5 grams of fat per kilogram of body

> weight.

>

> During another phase, the exercise period was again

> 30 minutes, but

> divided into three 10-minute sessions with a break

> of at least 20

> minutes between each session. Again, the milk shake

> meal followed 12

> hours later. And during the final phase, there was

> no exercise at all

> – just a period of inactivity, followed by the milk

> shake.

>

> Blood fat levels were measured five times: before

> each high fat meal,

> and at two, four, six and eight hours after each

> meal. For each

> subject, the three phases of the trial were

> separated by at least

> seven days and were performed in random order.

>

> The result: Cholesterol levels had very little

> statistical difference

> throughout the three phases. But the rise in

> triglycerides following

> the high fat meal was significantly lower during the

> phase using

> intermittent exercise, when compared to both no

> exercise and

> continuous exercise.

>

> Researchers concluded that a single session of

> intermittent exercise

> may be more effective than continuous exercise in

> managing

> postprandial lipemia.

>

>

---------------------------

>

> Push that strolling pace

>

---------------------------

>

>

> Larger studies will be needed to confirm the

> findings of the SMSU

> trial. Nevertheless, the SMSU results are promising

> for those whose

> lives are too hectic to carve out a chunk of 30+

> minutes each day for

> exercise.

>

> Dr. Thomas S. Altena of SMSU told Reuters Health

> that while the key is

> to get at least 30 minutes of exercise each day,

> those who break up

> the half hour into three short sessions of

> moderately intense exercise

> may actually be doing their heart more good than by

> getting their 30

> minutes all at once.

>

> He emphasized that a " slow stroll " is not

> sufficient, but three short,

> brisk walks may be all that's needed to boost

> cardiovascular benefits.

>

>

---------------------------

>

> Give it some muscle

>

---------------------------

>

>

> Or... you could do some weight lifting, which could

> add even more

> benefits to a heart-supportive workout regimen.

>

> In the e-Alert " Muscle Up " (2/12/04), I told you

> about the importance

> of doing exercises (such as weight training or

> resistance training)

> that are designed to strengthen muscles. This type

> of exercise yields

> several benefits, including reducing the risk of

> falls and fractures,

> promoting healthy bone density, and improving

> insulin sensitivity.

>

> And while weight training increases muscle strength,

> older people get

> another benefit: prevention of sarcopenia – the

> age-related loss of

> skeletal muscle.

>

> A recent report from the International Longevity

> Center-USA, details a

> variety of studies of subjects aged 60 to 96 who

> overcame the loss of

> strength and body mass associated with sarcopenia by

> using weight

> training regimens that lasted from 8 to 12 weeks. In

> as little as two

> sessions a week, most subjects increased their

> strength while also

> improving balance and mobility.

>

> The results from these and other exercise studies

> never vary: Those

> who get up and get moving tend to live longer and

> healthier.

>

> But easy does it.

>

>

************************************************************

>

> ...and another thing

>

> The term " monkey business " just took on a whole new

> meaning.

>

> It seems that monkeys go about their daily routines

> much as humans do.

> If they have one hour to get a half-hour job done,

> they tend to

> procrastinate and slack off for 40 minutes, and then

> scramble for 20

> to meet their deadline.

>

> Although what kind of pressing deadline a monkey

> might have is hard to

> imagine. (Yikes! Look at the time! I'm late for my

> tire swing

> appointment.)

>

> But researchers at the National Institute of Mental

> Health recently

> found a way to turn monkeys into overachieving

> workaholics. How? By

> monkeying around with their genes.

>

> The NIMH team developed a genetic technique that

> uses a DNA

> " antisense " agent to trick the brain into turning

> off the receptors in

> the D2 gene. With these receptors blocked, dopamine

> (a message-carrying

> chemical associated with rewards) couldn't get to

> any brain

> cells. Obviously, the science here is very

> complicated (and WAY over

> my head) so I'll just cut to the chase: No dopamine

> in the brain cells

> changed everything.

>

> Seven dopamine-deprived rhesus monkeys turned into

> primate versions of

> model employees. They went right to work, stayed on

> task, made very

> few errors, and didn't give a fig (or a peanut)

> about receiving a

> reward.

>

> NIMH researcher Dr. Barry Richmond told Reuters News

> that even though

> some employers might take an interest in the

> results, the purpose of

> the study is to understand mental illness.

>

> SOME employers? How about every CEO in the Fortune

> 500!?

>

> I'm all for conducting studies that will help us

> understand mental

> illness, but when genetic manipulation turns monkeys

> into workaholics,

> that's a little unsettling. It's just too easy to

> imagine a day when

> employees might be offered a bonus to have their D2

> receptors turned

> off by a DNA antisense agent. It sounds like

> Orwell's 1984 arriving a

> few decades late.

>

> Genetics will be the key to many wonderful medical

> breakthroughs in

> this century. But if we don't proceed with care,

> genetics could also

> be the key to Pandora's box.

>

> To Your Good Health,

>

> Jenny Thompson

> Health Sciences Institute

>

>

************************************************************

>

> Sources:

>

> " Single Sessions of Intermittent and Continuous

> Exercise and

> Postprandial Lipemia " Medicine and Science in Sports

> and Exercise,

> Vol. 36, No. 8, August 2004, ncbi.nlm.nih.gov

> " Exercise Spurts may Improve Blood Fats " Merritt

> McKinney, Reuters

> Health, 8/16/04, reutershealth.com

> " Growing Older, Staying Strong: Preventing

> Sarcopenia Through Strength

> Training " International Longevity Center - USA,

> Issue Brief,

> September-October, 2003, ilcusa.org

> " Gene Blocker Turns Monkeys into Workaholics "

> Reuters, 8/11/04,

> msnbc.com

>

> Copyright ©1997-2004 by www.hsibaltimore.com,

> L.L.C. The e-Alert may

> not be posted on commercial sites without written

> permission.

>

>

************************************************************

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