Shute Vitamin E Treatment Protocol

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Shute Vitamin E Treatment Protocol

 

Natural Alpha Tocopherol (Vitamin E) in the treatment

of Cardiovascular and Renal Diseases as suggested by

Drs. Wilfrid and Evan Shute and the Shute Institute

for Clinical and Laboratory Medicine, London, Ontario,

Canada.

 

Use only products labeled in terms of InternatIonal

Units (IU).

 

Acute coronary thrombosis: 450 to 1,600 IU a day

started as soon as possible and maintained.

 

Older cases of coronary thrombosis: 450 to 1,600 IU if

systolic pressure is under 160 Otherwise 450 IU for

the first four weeks, particularly if a hypotensive

agent is used concurrently.

 

Acute rheumatic fever: 450 to 600 IU daily.

 

Chronic rheumatic heart disease: give 90 IU daily

first month, 120 IU daily second month and 150 IU

daily for third month. 150 IU may be ideal dose.

Occasionally more is necessary and advisable. Response

will necessarily be slow.

 

Anginal Syndrome: 450 to 1,600 IU if systolic pressure

is under 160. Otherwise start on 150 IU for four weeks

then 300 IU for four weeks, particularly if

hypotensive agent is used.

 

Hypertensive heart disease: 75 IU daily for four

weeks, 150 IU daily for four weeks, then cautiously

increase. Should be used with hypotensive agents.

High doses of vitamin E have been shown to reduce high

blood pressure in rats with chronic kidney failure.

(Vaziri N. Hypertension, Jan 2002.)

 

Thrombophlebitis and Phlebothrombosis: 600 to 1,600 IU

daily.

 

Thrombocytopaenic Purpura: 800 to 1,200 IU daily.

 

Diabetes Mellitus: Same schedule as for cardiacs.

 

Acute and Chronic Nephritis: as for cardiac patients.

 

Burns, Plastic Surgery, Mazoplasia: 600 to 1,600 IU

daily, using vitamin E ointment or vitamin E spray as

adjunct. (Editor’s note: vitamin E may also be

dripped from a thumbtack-punctured capsule.)

 

 

CAUTIONS

 

The maintenance dose equals the therapeutic dose.

 

Do not take iron and vitamin E at same time. If iron

is indicated, separate the doses by about nine hours.

 

The digitalis requirement is often reduced after

vitamin E takes hold, so over-digitalization should be

avoided. A patient receiving vitamin E should not be

digitalized by the Eggleston massive dose technique

nor any of its modifications. It is usually sufficient

for full digitalization to give what is ordinarily a

maintenance dose of 1 1/2 grains digitalis folia or

0.1 mg digitoxin per day. By the second day the

patient is often digitalized.

 

Insulin dosages in diabetic cardiacs must be watched

closely, for the insulin requirement may be

considerably reduced very suddenly.

 

Hyperthyroidism is sometimes a contraindication.

 

Estrogens should rarely be given at the same time as

alpha tocopherol (vitamin E).

 

(Editor's note: The Shutes also recommend caution with

patients who have untreated high blood pressure, a

rheumatic heart, or congestive heart failure. If you

are a person with these or any other preexisting

medical condition, you need to WORK WITH YOUR

PHYSICIAN TO DETERMINE YOUR OPTIMUM VITAMIN E LEVEL.)

 

TWELVE EFFECTS OF ALPHA TOCOPHEROL (Vitamin E)

 

1. It reduces the oxygen requirement of tissues.

Hove, Hickman, and Harris (1945) Arch. Biochem. 8:395.

 

Telford et al (1954) Air University School of Aviation

Medicine Project #21-1201-0013, Report #4, May.

Randolph Field, Texas.

 

2. It melts fresh clots, and prevents embolism.

Shute, Vogelsang, Skelton and Shute (1948) Surg., Gyn.

and Obst. 86:1.

 

Wilson and Parry (1954) Lancet 1:486.

 

3. It improves collateral circulation.

Enria and Fererro (1951) Arch. per Ia Scienze Med.

91:23.

 

Domingues and Dominguez (1953) Angiologia 5:51.

 

4. It is a vasodilator.

Shute, Vogelsang, Skelton and Shute (1948) Surg., Gyn.

and Obst. 86:1.

 

5. It occasionally lyses scar tissue.

Steinberg (1948) Med. Clin. N. America 30:221, 1946.

 

6. It prevents scar contraction as wounds heal.

Shute, Vogelsang, Skelton and Shute (1948) Surg., Gyn.

and Obst. 86:1.

 

7. It increases low platelet counts.

SkeIton, Shute, Skinner and Waud (1946) Science

103:762.

 

8. It decreases the insulin requirement in about 1/4

of diabetics.

Butturini (1950) Gior. di Clin. Med. 31:1.

 

Tolgyes (1957) Summary 9:10.

 

9. It is one of the regulators of fat and protein

metabolism.

Hickman (1948) Rec. of Chem. Progress, p.104.

 

10. It stimulates muscle power.

Percival (1951) Summary 3:55.

 

11. It preserves capillary walls.

Ames, Baxter and Griffith (1951) International Review

of Vitamin Research 22:401.

 

12. It prevents haemolysis of red blood cells.

Rose and Gyorgy (1951) Fed. Proc.10:239. 1951.

 

 

OTHER RELEVANT PUBLICATIONS

 

Tolgyes, S. and Shute, E. V. (1957), Alpha Tocopherol

in the Management of Small Areas of Gangrene. Can. M.

A. J. 76:730.

 

Shute, E.V. (1957) The Prevention of Congenital

Anomalies in the Human: Experiences with Alpha

Tocopherol as a Prophylactic Measure. J. Ob. & Gyn.

Brit. Emp. 44:390.

 

Hauch, J. T. (1957) A New Treatment for Resistant

Pressure Sores. Can. M.A.J. 77:125.

 

Shute, E. V. (1957) Alpha Tocopherol in Cardiovascular

Disease. Oxford University Med. Gaz. 9:96.