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> " HSI - Jenny Thompson "

> <HSIResearch

 

> Big Bully

> Wed, 21 Jul 2004 08:26:11 -0400

>

> Big Bully

>

> Health Sciences Institute e-Alert

>

> Wednesday July 21, 2004

>

>

**************************************************************

 

>

> Dear Reader,

>

> Only a very small percentage of older adults in the

> U.S. are doing

> enough to keep their muscles strong, according to a

> report from the

> Centers for Disease Control and Prevention (CDC).

>

> This is a critical lapse for many reasons, but here

> are two good

> ones: 1) The moderate amount of exercise required to

> maintain

> muscles will yield other important health benefits.

> And 2) Keeping

> muscles strong is relatively easy.

>

> And now it may be even easier. According to a new

> study that

> appears in a recent issue of the journal Nutrition,

> key nutrients

> have been shown to help develop muscle mass and

> support

> physical functioning as we age.

>

>

-------

> Getting a grip

>

-------

>

> Because age-related muscle loss is associated with

> osteoporosis

> and an increased risk of falls, researchers at the

> Vanderbilt

> University Medical Center wanted to find out if an

> intake of three

> nutrients might provide a simple way to help prevent

> muscle loss.

>

> The Vanderbilt researchers recruited a group of 50

> women whose

> average age was about 77. Over a 12-week period, a

> " treatment

> group " of 27 women received a daily supplement

> containing 1.5

> grams of lysine, 2 grams of

> beta-hydroxy-beta-methylbutyrate, and

> 5 grams of arginine. (I'll tell you more about these

> three nutrients

> in a moment.) A second group of 23 women received a

> placebo.

>

> Before and after the trial period, several

> measurements were taken

> to determine potential changes in muscle mass:

>

> * Whole-body protein synthesis and loss (estimated

> with a

> specially designed blood test)

> * Limb, hip and abdomen circumference

> * Leg and handgrip strength

> * Physical functionality

> * Levels of hormones that affect proteins

> * Percentage of lean body mass and body fat

>

> The hormone levels of both groups remained the same,

> but the

> treatment group improved in all other categories

> compared to the

> placebo group. The treatment group also had a

> significant increase

> in the average circumference of limbs, and their

> protein synthesis

> increased approximately 20 percent, compared to

> placebo subjects.

>

> Researchers concluded that a daily supplement of

> these three

> nutrients may play an important role in muscle

> health, while

> improving functionality, protein synthesis and

> strength in older

> women.

>

>

------

> The multi-tasker

>

------

>

> According to Healthnotes Newswire, the average

> person over the

> age of 70 may experience muscle loss as high as 15

> percent per

> decade. So a 12-week trial can't begin to show an

> accurate picture

> of the long-term benefits of these nutrients.

> Nevertheless, the

> results of the Vanderbilt research provide a basis

> to consider

> supplementing with the nutrients studied, especially

> for older

> people who may be incapacitated in some way that

> prohibits

> exercise.

>

> In the e-Alert " Five Stars " (8/26/03), I told you

> about arginine

> (also known as L-arginine), which is a remarkable

> amino acid,

> known to play a role in blood vessel dilation,

> reduction of

> inflammation, repair of skin and connective tissue,

> and thymus

> gland regulation. Arginine has also been shown to

> facilitate muscle

> metabolism by reducing body fat while increasing

> muscle mass.

>

> Dietary sources of arginine include diary products,

> meat, poultry

> and fish, as well as nuts, rice, whole-wheat, soy

> and raisins.

>

>

------

> Plus two...

>

------

>

> In the Health e-Tips e-letter " Keeping Your Extra

> Parts " (5/13/04),

> Amanda Ross explained that lysine – an essential

> amino acid – has

> been used to increase calcium absorption and may

> help prevent

> osteoporosis. In supplement form, high doses of

> lysine may raise

> cholesterol levels and increase the risk of

> gallstones, so lysine

> supplementation should be monitored by a

> nutritionally oriented

> physician. Dietary sources of lysine include meat,

> fish, dairy

> products, legumes and brewer's yeast.

>

> The third nutrient in the Vanderbilt study is

> beta-hydroxy-beta-

> methylbutyrate (HMB), a derivative of the amino acid

> leucine.

> HMB is not widely studied in humans, but animal

> tests show that it

> may improve the growth of lean muscle tissue by

> slowing protein

> breakdown. The dietary sources of HMB are limited to

> small

> amounts in citrus fruits, catfish and alfalfa.

>

>

------

>

> Up off the duff

>

------

>

> So... let's say you check with your doctor about

> these three

> nutrients, he gives you the green light to monitor

> supplementation,

> and in time they begin strengthening your muscles.

> That's great.

> But for older people who are able, exercise is still

> the most

> effective way to support muscle strength. And more

> specifically,

> exercise that incorporates weight training or

> resistance training will

> yield the best results, including:

>

> * Reducing the risk of falls and fractures

> * Increasing endurance

> * Promoting healthy bone density

> * Improving insulin sensitivity

>

> The National Institute on Aging (NIA) has published

> a free

> guidebook for starting an exercise program, which is

> available on

> their web site: nia.nih.gov/exercisebook. The book

> provides a

> section on diet advice that offers the outdated and

> misguided

> USDA food pyramid as a dietary guideline, but other

> than that,

> you'll find useful tips for starting and staying

> with a strength

> exercise regimen.

>

>

**************************************************************

 

> ...and another thing

>

> There's no other word to describe it except for

> outrage.

>

> Last week, a U.S. district court stopped the sale of

> three very

> popular natural therapies: BeneFin, SkinAnswer and

> MGN-3.

>

> Upon hearing that, one would assume these products

> must have

> been responsible for countless deaths and had swarms

> of customers

> shouting for their recall.

>

> In fact, none of these products were proven to be

> harmful or

> ineffective nor was the action based on customer

> complaints. The

> FDA accused LaneLabs (their manufacturer) of making

> claims that

> qualified the products as unapproved new drugs,

> requiring formal

> FDA approval. After a lengthy legal process, the

> court agreed and

> ordered LaneLabs to cease production and sale of the

> products.

>

> That action alone would have been sufficient in

> order to stop the

> marketing practices the FDA objected to. But the

> judge took it

> much further, dealing an essentially fatal blow. He

> also ordered

> LaneLabs to destroy the remaining inventory of all

> three products,

> except for an amount of BeneFin needed to complete a

> National

> Cancer Institute study. In addition, LaneLabs may be

> ordered to

> reimburse all of the customers who purchased these

> products since

> 1999. It's important to note that this isn't limited

> to customers who

> requested their money back. It's EVERYONE that

> bought one of

> these three products in the last four years.

>

> Given that the FDA complaint concerned only

> marketing practices

> – not efficacy or safety – these court orders border

> on the insane.

> And they should act as a loud wake up call for the

> entire industry.

>

> The court probably feels contently smug, knowing it

> has punished

> LaneLabs, and possibly put this innovative

> manufacturer out of

> business. But ultimately it is the consumer being

> punished by

> losing access to these products, which have all been

> proven to be

> useful. So, in order to protect us from marketing

> language, the

> court is willing to take away our protection from

> serious illnesses.

>

> Throughout the years, we have recommended many

> LaneLabs

> products, including the targets in this action. In

> each case, we

> believed the therapies to be beneficial and safe,

> and we received

> encouraging testimonials from members who tried them

> and were

> happy with the results. We continue to stand behind

> our belief that

> LaneLabs is a revolutionary company that could have

> – and may

> still – change the face of American medicine.

>

> In the meantime, with BeneFin, SkinAnswer and MGN-3

> now

> unavailable to you, we will ask our HSI panelists

> and researchers

> to continue looking for natural and effective

> therapies that deliver

> the same safe alternatives to mainstream medicine

> that these

> products provided. As we discover them, we'll tell

> you about them

> in upcoming e-Alerts and HSI Members Alerts.

>

> But our hope is that LaneLabs' products will soon be

> readily

> available again to those who need them most, here in

> the land of

> the free.

>

> To Your Good Health,

>

> Jenny Thompson

> Health Sciences Institute

>

>**************************************************************

>

> Sources:

> " Effect of Beta-Hydroxy-Beta-Methylbutyrate,

> Arginine, and

> Lysine Supplementation on Strength, Functionality,

> Body

> Composition, and Protein Metabolism in Elderly

> Women "

> Nutrition, Vol. 20, No. 5, May 2004,

> ncbi.nlm.nih.gov

> " Battle Age-Related Muscle Loss with Amino Acid

> Combination "

> Kimberly Beauchamp, ND, Healthnotes Newswire,

> 6/24/04,

> pccnaturalmarkets.com

> " Strength Training Among Adults Aged >65 Years "

> Morbidity and

> Mortality Weekly Report, Centers for Disease Control

> and

> Prevention, Vol. 53, No. 2, 1/23/04, cdc.gov

> " Strength Training Urged for Elderly " Merritt

> McKinney, Reuters

> Health, 1/23/04, story.news.

> " Growing Older, Staying Strong: Preventing

> Sarcopenia Through

> Strength Training " International Longevity Center -

> USA, Issue

> Brief, September-October, 2003, ilcusa.org

> " Judge Halts Sale of Herbal Remedies " Susan

> Star-Ledger,

> 7/13/04, nj.com

>

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