Prostate Cancer -Is it Mainly because of the meat?

[Guest guest]

Professor Antonio Avocado (vegscience.vegsource.org)

Prostate cancer - Is it mainly because of the meat?

June 10, 1999 at 19:15:04 PST

 

Prostate cancer - Is it mainly because of the meat?

 

CHARLOTTESVILLE, VIRGINIA. Prostate cancer is now the most

commonly diagnosed cancer among American and European men. It is also common in

Eastern countries, but the incidence of fatal, metastatic

prostate cancer is much lower there. This suggests that some dietary or

environmental factor is involved in determining whether prostate cancer spreads

to other organs or not. Researchers at the University of Virginia Cancer Center

believe they have uncovered an important clue to the puzzle. Their experiments

have shown that arachidonic acid, an omega-6 fatty acid mainly found in meat and

animal products, stimulates the growth of prostate cancer cells through the

production of a metabolite, 5-HETE (5-hydroxyeicosatetraenoic acid). The

researchers found that 5-HETE is essential for the survival of prostate cancer

cells and that these cells are completely eradicated (in vitro) in a few hours

by blocking the production of 5-HETE. They conclude that a high intake of

dietary fats accelerates the progression of prostate cancer and that arachidonic

acid is intimately involved in this process. They also suggest that drugs which

inhibit the formation of 5-HETE may prove useful in the battle

against prostate cancer.

 

Ghosh, Jagadananda and Myers, Charles E. Inhibition of arachidonate

5-lipoxygenase triggers massive apoptosis in human prostate cancer cells.

Proceedings of the National Academy of Sciences USA, Vol.

95, No. 22, October 27, 1998, pp. 13182-87

 

http://www.vegsource.com/talk/science/messages/326.ht

 

 

'); //-->

 

 

 

Posted: Thu Jun 03, 2004 4:25 pm Post subject: Fat and Prostate Cancer

 

 

Fat and prostate cancere has been talked about often. What kind is good, what

kind is bad, what might prevent localized disease, what might prevent

metastasis. It is all here in this December 1998 Prostate Forum Newsletter. Is

PGE-2, 5 HETE, 12 HETE good for you and where does it come from.

 

Listed below is the Key points of this excellent issue. It will be quoted many

times in the future. You will have to call their office for copies. I think this

is an important issue for those wondering about the effects of fat on prostate

cancer.

--

Prostate Forum

P.O. Box 6696

Charlottesville, VA 22906-6696

Tele 804-974-1303 FAX 804-974-9597

E-mail: rmyers

http://www.prostateforum.com

 

Editor

Charles H. Myers, Jr. MD

 

The Prostate Forum is published monthly in Charlottesville, Virginia by Rivanna

Health Publications, Inc.

Subscriptions: $36 a year

1998 Prostate Forum

Rivanna Health Publications. Inc.

 

KEY POINTS

 

* Fat is composed of a glycerin backbone with three fatty acids attached. The

different fatty acids make one fat different from another.

 

* It is uncommon for an adult to become deficient in essential fatty acids. I

think most Americans suffer from excessive amounts of " essential fatty acids " in

their diets.

 

* Unsaturated fats fall into three major groups, omega 3, omega 6 or omega 9.

 

* Arachidonic acid, an omega 6 fatty acid, is converted into a number of

hormones with negative effects on prostate cancer cells.

 

* Most of the arachidonic acid in [a OUr diet comes from meat, dairy t, and egg

yolks.

 

* Prostaglandin E2 is one product made from arachidonic acid. It can disable or

kill immune cells important in controlling cancer.

 

* Arachidonic acid can be converted into 12-HETE, a hormone which stimulates

cancer cell invasion and new blood vessel formation (angiogenesis).

 

* Arachidonic acid can be converted into 5-HETE, a hormone which can promote the

survival and growth of prostate cancer cells.

 

* Saw palmetto, pygeum africanum, PC-SPES, and other herbs can block arachidonic

acid conversion to these hormones.

 

Fat and Prostate Cancer

 

In past issues of this newsletter we have presented evidence that a diet rich in

fat, especially animal fat, increases the risk of prostate cancer. We reviewed

the information suggesting that fat may also be dangerous to men already

diagnosed with prostate cancer.

 

Over the past two years, there have been dramatic advances in our understanding

of how dietary fat promotes the development of prostate cancer. Components of

dietary fat have been shown to stimulate the spread and growth of human prostate

cancer.

 

As cancers grow, they need to form new blood vessels to supply added food and

oxygen. A component of fat can dramatically enhance new blood vessel formation

by prostate cancer cells. The immune response to cancer involves both natural

killer cells and T cells that are also able to kill cancer cells. Prostate

cancer cells can use dietary fat to produce chemicals capable of killing or

disabling both of these immune cells. In summary, certain dietary fats allow the

cancer cells to grow and survive, evade the immune sys tern, and spread to

distant parts o£ the body

_________________

 

 

JoAnn Guest

mrsjoguest

DietaryTipsForHBP

http://www.geocities.com/mrsjoguest

 

 

 

 

 

 

 

 

The complete " Whole Body " Health line consists of the " AIM GARDEN TRIO "

Ask About Health Professional Support Series: AIM Barleygreen

 

" Wisdom of the Past, Food of the Future "

 

http://www.geocities.com/mrsjoguest/AIM.html

 

PLEASE READ THIS IMPORTANT DISCLAIMER

We have made every effort to ensure that the information included in these pages

is accurate. However, we make no guarantees nor can we assume any responsibility

for the accuracy, completeness, or usefulness of any information, product, or

process discussed.

 

 

 

 

 

 

 

 

 

Friends. Fun. Try the all-new Messenger