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Bitter Melon Fruits Include Components Resembling Insulin

 

BITTER MELON (MOMORDICA CHARANTIA) Other botanical names include:

Bitter Melon is a common vegetable. Eaten by many throughout the

world. Bitter Melon grows on a vine and is cousin of the squash.

The bitter melon has green cucumber shaped fruit.

 

Bitter melon isn't its only name.

Botanists and scientists call it--

Momordica charantia (botanical name).

 

There are many nick-names, including bitter gourd, carilla

plant,wild cucumber,Kuguazi,

African cucumber, karela, and its medicinal herb name in china, Kuguazi.

 

 

Bitter melon is science-friendly. For example, you can find it in

the " MERCK INDEX " , the chemist's and physician's encyclopedia of

chemicals,drugs and biologicals.

 

WHERE DOES IT COME FROM?

 

Bitter melon is native to almost all tropical climates. It is common

inAfrica, China, the Far East, India, Brazil, the Caribbean, etc.

 

HERE IN PART IS WHAT THE U.S. DEPARTMENT OF AGRICULTURE SAYS ABOUT

BITTER MELON:

 

" Bitter melon is used for tumors in Brazil, for malignant ulcers in

Guam. Arubans take the decoction for hypertension, Puerto Ricans for

diabetes; Hondurans as a depurative;

Peruvians for colic and worms.

 

Jamaicans for colds, constipation, fever and stomachache; Congolese

use the leaf for colic, the seed for roundworm.

 

Japanese use the plant for constipation, headache, and skin

ailments.... " *James A. Duke, PhD., Chief, Germplasm Resources

Laboratory, United States Dept. of Agriculture, Washington, D.C.,

quoted from HANDBOOK OF MEDICINAL HERBS (1985;pp315-316)

 

 

WHAT IS THE SCIENTIFIC RESEARCH DATA ABOUT BITTER MELON?

Some research scientists are concerned with leukemia or lymphoma.

Others with the immune system. Some research AIDS and HIV-1.

Others seek proteins that have immunosuppressive effect. Still

otherslook for hypoglycemic peptides. Some look for extracts that

kill

human leukemic lymphocytes. Some are interested in the highest

neutral detergent fiber or monoclonal antibodies or the lowering of

 

glucose concentrations or stimulators

of insulin release.

 

We think you will agree, that there is some- thing unique about this

plant.

Re: Its lowering of glucose concentrations, improving glucose

tolerance, and promoting glucose disposal:

" The mineral and amino acid analysis showed that the bitter gourd

contained nutritionally useful quantities of the most essential

mineral and amino acids.

 

The blood sugar once lowered after 30 days did not increase even

after

15 days of discontinuation of the treatment. " *

*Journal of Ethnopharmacology 15(1):107-17 1986 Jan.

 

" Investigations were carried out to evaluate the effect of Momordica

charantia on the glucose tolerance of maturity onset diabetic

patients.

 

 

The juice of Momordia charantia was found to significantly improve

the glucose tolerance of 73% of the patients investigated. " *

*Journal of Ethnopharmacology 17(3):277-82 1986 Sept.

 

" Cerrasee-A wild variety of Momordica charantia is traditionally

prepared as a tea for the treatment of diabetes mellitus in the West

Indies and Central America.

*Diabetes Research Clinical & Experimental 2(2):81-4 1985 Mar.

 

" The hypoglycaemic effect of orally administered extracts of fruits

of

cultivated Momordica charantia (Karela) was examined.

 

The results suggest that orally administered karela extracts lower

glucose concentrations independently of intestinal glucose

absorption

and involve an extra pancreatic effect. " *

*Planta Medica 56(5); 426-9 1990 Oct.

 

" The effect of Karela (Momordica charantia), a fruit indigenous to

South America and Asia, on glucose and insulin concentrations was

studied in nine non-insulin-dependent diabetics and six non-diabetic

rats.

These results show that karela improves glucose tolerance in

diabetes.

Doctors supervising *Asian* diabetics are aware of the fruit's

hypoglycemic properties. " **British Medical Journal-Clinical Research

 

282(6279); 1823-4 1981June 6.

 

" An aqueous extract from the unripe fruits of the tropical plant

Momordica charantia was found to be potent stimulator of insulin

release from beta cell rich pancreatic islets isolated from

obese-hyperglycemic mice.

Studies of 45 Ca fluxes suggest that the insulin releasing action is

aresult of perturbations of membrane functions. In support for the

idea

of direct effects on membrane lipids, the action of the extract was

found to mimic that of saponin. " *

*Acta Biologica et Medica Germanica 41(12):1229-40 1982.

 

" A hypoglycemic peptide, Polypeptide-p has been isolated from the

fruit seeds and tissue of Momordica charantia.

 

Polypeptide-p is a very effective hypoglycemic agent when

administered

subcutaneously to gerbils, langurs and humans. " *

*Journal of Natural Products 44(6):648-55 1981 Nov.-Dec.

 

" Extracts of Momordica charantia fruit pulp, seed, and whole plant

were

tested for their hypoglycemic effects on normal and diabetic rat

models.

 

The results indicate the presence of non-sapogenin hypoglycemic

compound(s) in Momordica charantia fruit pulp and the activity is

probably mediated either by improving the insulin secretory capacity

of

the B cells or by improving the action of the insulin. " *

*Planta Medica 59(5):408-412 1993

 

" The Bitter Melon or Balsam Pear--

is cultivated as a tropical vegetable in South America, Asia, and

Africa where it has been used as a traditional therapy for diabetes

in a

variety of cultures of these countries.

 

One isolate of Momorica, Charantin is a mixture of steroidal

glycosides

and compares favorably to " tolbutamide " , an allopathic drug commonly

used as a oral hypoglycemic agent.

Another isolate, polypeptide-P has been shown to lower blood glucose

when administered via subcutaneous injections.

A variety of oral extracts have been shown to lower blood sugar and

improve glucose

tolerance in both human and animal studies.

 

*Chakravarthy BK, Gupa S, and Gode KD:

Functional beta cell regeneration in the islets of Pancreas in

alloxan

induced dibetic rats by epicatechin. Life Sc 31:2693-7, 1982

" ....The results indicated that M. charantia fruits and seeds

contained

components that resembled insulin in inhibiting hormone-induced

lipolysis... " *

*Wong CM, Yeung HW, Ng TB: Screening of (family Cucurbitaceae) for

compounds with antilipolytic activity.

*Journal of Ethnopharmacology 13(3):313-21, July 1985.

 

http://home.istar.ca/~hlth2000/bittermelon.html

*CLICK HERE to view Published Clinical Articles on MOMORDICA

CHARANTIA

---

 

BITTER MELON AS AN ALTERNATIVE TREATMENT FOR DIABETES

Momordica charantia

 

In Myanmar (Burma), China and India, it is highly prized for its

anti-diabetic activity.

Myanmar traditional physicians prescribe

bittermelon to diabetic patients.

 

Doctors in India are so confident of bitter melon's positive effect

on diabetes,

they dispense bitter melon in some of the most modern hospitals.

 

According to James Duke of U.S Department of Agriculture, bitter

melon has attained favor in China as a monoherbal medicine for

diabetes mellitus.

 

Bitter melon has twice the potassium of bananas, and it has been

shown

to increase the number of beta cells,

those which produce insulin, in the pancreas.

 

PREPARATION-

Bitter melon is available through most Filipino and/or Asian grocery

stores, and some farmers markets.

 

The appropriate method of administering bitter melon is to make the

extract from the fruit, vines, and leaves of the plant and either

drink it as a juice, tea or administer it as a retention enema.

 

Some say that drinking the juice or tea will result in the breakdown

of

the active components by stomach acids, therefore a retention enema

would be a more efficient route.

 

 

Momordica charantia (Bitter melon):

Therapeutic Actions, Clinical Indications, and more

Diabetic and Other Metabolic Neuropathies Abstracts

 

THE INFLUENCE OF MOMORDICA CHARANTIA FRUIT JUICE

ON PERIPHERAL NERVE

STRUCTURE IN EXPERIMENTAL DIABETES

 

Serasee is believed to work in a holistic manner. It is believed to

work best if your food and water

are clean and natural, and your heart and mind are pure. If you eat

foods with a lot of chemicals it won't work so well.

 

If you are full of toxins, use sparingly at first, as purification

reactions may be strong

 

Mormodica works from the subtlest levels to adjust you toward

health, and works best with your total cooperation in the way of

diet, attitude, etc.

---

---GLA in Borage Oil Useful in Diabetic Neuropathy

 

Results of GLA (gamma linolenic acid) as found in

evening primrose oil and Borage oil supplementation in diabetics

truly

 

astounding.

 

Stein et al, in their research at the Department of Internal

Medicine, Center for Diabetes Research at the University of Texas

Southwestern Medical Center Dallas Texas have conclusively

demonstrated the vital importance of oils that contain the essential

Omega three fatty acids.

 

These Omega three's as well as an important Omega six are the EFA's

LNA

and LA. When we lack them in our diet, we suffer degenerative

disease

Research shows the role certain beneficial fatty acids may play in

preventing or improving cardiovascular complications attributed to

diabetes.

 

" Perhaps of equal or greater importance is the role certain

beneficial fatty acids may play in preventing or improving

cardiovascular complications attributed to diabetes.

 

Buried in the annals of medicine are extremely optimistic studies

attesting to these facts.

 

This information has not been widely publicized in the past because

fatty acids are naturally occurring nutrients and can

not be patented by pharmaceutical companies and sold at exorbitant

prices. One such fatty acid, gamma linolenic acid (GLA), is found in

nature's most concentrated form as Borage seed oil (24% GLA). The

results of GLA supplementation in diabetics are truly astounding, as

outlined below.

 

Diabetic neuropathy (a painful nerve disorder resulting from reduced

blood flow and subsequent oxygen depravation of the limbs or organs)

was reversed in studies conducted by seven medical centers.

 

In a separate, but similar study, 12 patients afflicted with

diabetic

neuropathy were given 360 mg of GLA daily (the equivalent of two,

1000 mg. Borage oil capsules), while 10 others were given a placebo

(inactive substance).

 

After 6 months the GLA group showed statistically significant

improvement as compared to the placebo group.

In addition, GLA supplementation has been reported to normalize the

faulty fatty acid metabolism attributed to diabetes by bypassing the

enzyme system responsible for this disorder

 

By doing so the body's response to inflammation, pain and swelling

is stabilized.

 

Arterial muscle tone, responsible for blood pressure and optimal

circulation, is also regulated by this system.

 

Animal studies conducted with GLA have revealed the normalization of

intercellular sorbitol levels.

Another study of Type 1 diabetics cited favorable changes in HDL

( " good " cholesterol) and blood platelet adhesiveness with GLA

supplementation.

 

 

Research shows the role certain beneficial fatty acids may play in

preventing or improving cardiovascular complications attributed to

diabetes.

" Perhaps of equal or greater importance is the role certain

beneficial fatty acids may play in preventing or improving

cardiovascular complications attributed to diabetes.

 

Buried in the annals of medicine are extremely optimistic studies

attesting to these facts.

 

This information has not been widely publicized in the

past because fatty acids are naturally occurring nutrients and can

not be patented by pharmaceutical companies and sold at exorbitant

prices.

 

One such fatty acid, gamma linolenic acid (GLA), is found in

nature's most concentrated form as Borage seed oil (24% GLA). The

results of GLA supplementation in diabetics are truly astounding, as

outlined below.

 

In a separate, but similar study, 12 patients afflicted with

diabetic neuropathy were given 360 mg of GLA daily

(the equivalent of two, 1000 mg. Borage oil capsules),

while 10

others were given a placebo (inactive substance). After 6 months the

GLA group showed statistically significant improvement as compared

to the placebo group. In addition, GLA supplementation has been

reported to normalize the faulty fatty acid metabolism attributed to

diabetes by

bypassing the enzyme system responsible for this disorder

 

By doing so the body's response to inflammation, pain and swelling

is stabilized. Arterial muscle tone, responsible for blood pressure

and

optimal circulation, is also regulated by this system. Animal

studies conducted with GLA have revealed the normalization of

intercellular sorbitol levels.

Another study of Type 1 diabetics cited favorable

changes in HDL ( " good " cholesterol) and blood platelet adhesiveness

 

In summary, diabetics have been found to possess faulty fatty acid

metabolism which may contribute to the cardiovascular complications

associated with the disease.

 

Scientific research has established the reduction of certain harmful

fats, with the addition of beneficial fatty acids, may offer a

significant breakthrough in combating diabetic cardiovascular

complications with the potential of significantly lowering health

care costs. "

 

The study concluded that all diabetics should be considered for a

dietary protocol of GLA.

 

The good news is that although this disease accounts for almost half

of the annual death toll from all causes, it is, in most cases,

curable-

permanently, quickly, economically, completely and often

easily and by natural means.

 

Let's not sugarcoat it:

 

Glucose-lowering drugs can do more harm than

good. The natural therapies used at the Whitaker Wellness Institute

for diabetes help keep blood sugar levels in check without the side

effects of drugs.

 

These drugs usually succeed in lowering blood sugar levels, but may

increase the *death* rate from heart attacks.

(this is listed as a common side effect!)

 

These drugs also are associated with weight gain, elevated

cholesterol and triglyceride levels, nausea, diarrhea, constipation,

 

stomach pain, drowsiness, and headache.

 

 

The Natural Pharmacist: Natural

Treatments for Diabetes includes up-to-date information on diabetes

and chromium,alphalipoic acid, evening primrose oil, fenugreek,

Gymnema

sylvestre, magnesium, Momordica charantia, Coccinia indica,

Pterocarpus marssupium, niacinamide, bilberry treatments.

--

-

 

Choose Your Fats: Diabetes & Weight Gain

JoAnn Guest

Apr 04, 2003 11:21 PST

 

Diabetes

 

In this discussion, diabetes refers to diabetes mellitus. Other

forms of diabetes (such as diabetes insipidus)are not included.

People with diabetes cannot properly process glucose, a sugar the

body uses for energy. As a result, glucose stays in the blood,

causing blood glucose to rise.

 

At the same time, however, the cells of the body can be starved for

glucose. Diabetes can lead to poor wound healing, higher risk of

infections, and many other problems involving the eyes, kidneys,

nerves,and heart.

 

In type 1 diabetes, the pancreas cannot make the insulin needed to

process glucose.

 

Adult-onset diabetes is also called type 2, or non-insulin-

dependent, diabetes. With type 2 diabetes, the pancreas often makes

enough insulin, but the body has trouble using the insulin.

Type 2 diabetes responds well to natural therapies.

 

People with diabetes have a high risk for heart disease and

atherosclerosis.

In addition, those with diabetes have a higher

mortality rate if they also have high homocysteine levels.

 

Checklist for Diabetes-

Rating Nutritional Supplements- Herbs

 

Alpha lipoic acid

Brewer's yeast (providing approximately 60 mcg of chromium per

tablespoon)

Chromium

Evening primrose oil, Borage Oil

 

Magnesium

Cayenne (topical for neuropathy)

Fenugreek (seeds)

Psyllium

Biotin

Coenzyme Q10

L-carnitine

Vitamin B1 (Thiamine)

Vitamin B6 (gestational diabetes only)

Vitamin C

Vitamin E (for prevention of retrolental fibroplasia in premature

infants, and for prevention of diabetic retinopathy)

Zinc (preferably for those with a documented deficiency)

Aloe vera

Bilberry

Bitter melon

Gymnema

Hairy Basil (seed)

Holy Basil (leaf)

Onion

Fish oil (EPA/ DHA)

 

The following are associated with diabetic retinopathy:

 

Selenium,

vitamin A, vitamin C, and vitamin E (combined)

Fructo-oligosaccharides (FOS)

Inositol

Manganese

Medium chain triglycerides

Quercetin

Taurine

Vanadium (for type 2 diabetes)

Vitamin B12

Vitamin B3 (niacinamide)

Vitamin D

Vitamin E (associated with abetalipoproteinemia) Eleuthero

Ginkgo biloba

Olive leaf

Reishi

 

Dietary changes that may be helpful:

 

The relationship between eating carbohydrates and type 2 diabetes is

a

complex issue. While eating

carbohydrates increases the need for insulin to keep blood sugar

normal, diets high in total complex carbohydrates do not necessarily

increase the risk of type 2 diabetes.

 

 

Years ago, one researcher reported an increase in diabetes among

Yemenite Jews who had migrated from a region where no sugar was

eaten to one in which they ate a diet including sugar.

However, other factors, such as " weight gain " , may explain the

increased risk of diabetes that occurred in this group.

 

Eating carbohydrate-containing foods, whether high in sugar or high

in starch (i.e. breads with hydrogenated fats,refined processed

breakfast cereals high in sugar), temporarily raise blood sugar and

insulin levels.

 

The blood sugar-raising effect of a food, called its " glycemic

index, " depends on how rapidly its carbohydrate is absorbed.

 

Many starchy foods have a glycemic index similar to sucrose (table

sugar).

 

People eating large amounts of foods with high glycemic indices

(such as those mentioned above), have been reported to be at

increased

risk of type 2 diabetes.

On the other hand, eating a diet high in

carbohydrate-rich foods with low glycemic indices is associated with

a low risk of type 2 diabetes.

 

Beans, peas, fruit, and oats, have low glycemic indices, despite

theirhigh carbohydrate content,

due mostly to the health-promoting effects of " soluble " fiber.

 

Diabetes disrupts the mechanisms by which the body controls blood

sugar.

 

Most doctors recommend that people with diabetes eliminate intake of

 

sugar from refined snacks and processed foods, and replace these

foods

with high-fiber, whole foods.

 

This tends to lower the glycemic index of the overall diet and has

the

additional benefit of increasing vitamin and

mineral intake.

 

A high-fiber diet has been shown to work better in controlling

diabetes than the diet recommended by the ADA, and may control blood

sugar levels as well as oral diabetes drugs.

 

In the study, the increase in dietary fiber was accomplished

exclusively through the consumption of foods naturally high in

fiber—such as organic leafy green vegetables and fresh wholefruit—to

a

 

level beyond that recommended by the ADA.

 

No fiber supplements were given. All participants received

both the ADA diet (providing 24 grams of fiber per day) and the high-

fiber diet (providing 50 grams of fiber per day), for a period of

six weeks.

 

After six weeks of following each diet, tests were

performed to determine blood glucose, insulin, cholesterol,

triglyceride, and other values. When glucose levels were monitored

over a 24-hour period, participants eating the high-fiber diet had

an average glucose level that was 10% lower than participants eating

the ADA diet.

 

Insulin levels were 12% lower in the group eating the

high-fiber diet compared to the group eating the ADA diet,

indicating a beneficial increase in the body's sensitivity to

insulin.

 

Moreover, people eating the high-fiber diet experienced

significant reductions in total cholesterol, triglycerides, and LDL

( " bad " ) cholesterol compared to those eating the ADA diet. They also

had slight decreases in glycosylated hemoglobin, a measure of

chronically high blood glucose levels.

 

High-fiber supplements, such as psyllium, guar gum (found in

beans),24 pectin (from fruit) oat bran, and psyllium

have improved glucose tolerance in some studies.Positive results

have

 

also been reported with the consumption of 1–3

ounces of powdered fenugreek seeds per day.

 

Many doctors advise people with diabetes to eat a diet

high in fiber.Focus should be placed on vegetables, seeds, oats, and

 

organic whole-grain products.

 

The fatty acids (omega-3s) in cold water fish also may afford some

 

protection from diabetes.

Incorporating a fish meal (alaskan salmon for example) into a

 

weight-loss regimen was more

effective than either measure alone at improving glucose and insulin

metabolism and high cholesterol.

 

Vegetarians have been reported to have a low risk of type 2

diabetes.When people with diabetic nerve damage switch to a vegan

diet (no meat or dairy), improvements have been reported

after several days.In one trial, pain completely disappeared in

17 of 21 people.

 

Fats from meat and dairy also contribute to abnormally high

triglyceride and homocysteine levels leading to heart disease, the

leading killer of people with diabetes.

 

Vegetarians also eat less protein than do meat eaters. The reduction

of protein intake has lowered kidney damage caused by diabetes

and may also improve glucose tolerance.

 

Diets high in fat, especially saturated fat, worsen glucose

tolerance and increase the risk of type 2 diabetes, an

effect that is simply the result of weight gain caused by eating

high-fat foods.Saturated fat is found primarily in meat, dairy fat,

and the dark meat and skins of poultry. In contrast, glucose

intolerance has been improved by diets high in " monounsaturated "

oils,which may be good for people with diabetes.

 

 

There is often difficulty in changing the overall percentage of

calories from fat and carbohydrates in the diets of people with type

1 diabetes.

However, modifying the quality of the dietary fat is achievable. In

adolescents with type 1 diabetes, increasing " monounsaturated " fats

(fat in almonds,macademia nuts, extra-virgin olive oils and

avocadoes)

 

relative to other fats in the diet is associated with better control

over blood sugar and cholesterol levels.

The easiest way to incorporate monounsaturates into the diet is to

use extra-virgin olive oil.

 

Should children avoid milk to prevent type 1 diabetes? Worldwide,

children whose dietary energy comes primarily from dairy (or meat)

products have a significantly higher chance of developing type 1

diabetes than do children whose dietary energy comes primarily from

vegetable sources.

 

Countries with high milk consumption have a high risk of diabetes.

Animal research also indicates that

 

*avoiding* milk affords protection from type 1 diabetes.

 

Milk contains a protein related to a protein in the pancreas, the

organ

 

where insulin is made.

 

Some researchers believe that children who are allergic to milk may

develop antibodies that attack the pancreas, causing type 1

diabetes.

 

Several studies have linked cows' milk consumption to the occurrence

of diabetes in children.

Some children who drink cows'milk produce antibodies to the milk,

and

it has been hypothesized that these antibodies can cross-react with

and *damage* the insulin-producing cells of the pancreas.

 

Lifestyle changes that may be helpful: Most people with type 2

diabetes are overweight.

 

Excess abdominal weight does not stop insulin formation, but it does

make the body less sensitive to insulin.

 

Excess weight can even make healthy people pre-diabetic. Weight loss

 

reverses this problem. In most studies,

type 2 diabetes has improved with weight loss.

Being overweight also increases the need for insulin.

 

Therefore, people with diabetes should achieve and maintain

appropriate body weight.

 

Exercise helps decrease body fat and improve insulin

sensitivity. People who exercise are less likely to develop type 2

diabetes than those who do not.However, exercise can induce low

blood

 

sugar or even occasionally increased blood sugar.

 

Moreover, a preliminary study has shown that long-term physical

activity was not associated with control of blood glucose in people

with

type 1 diabetes. Therefore, people with diabetes should never begin

an intensive exercise program without consulting a healthcare

professional.

 

--

--------------------------------

Dietary Fiber for Diabetics-

 

Effects of dietary fiber on glucose and lipoprotein metabolism

in diabetic patients

 

G Riccardi and AA Rivellese Institute of Internal Medicine and

 

Metabolic Diseases,

Second Medical School, University of Naples, Italy.

--------------------------------

Dietary recommendations for the treatment of diabetic patients

issued by

national and international diabetes associations consistently

emphasize the need to increase *complex* carbohydrate consumption.

 

However, these recommendations have been questioned on the basis of

growing evidence that, in both insulin-dependent and

non-insulin-dependent diabetic patients, a high-carbohydrate diet

does

not offer any advantage in terms of blood glucose and plasma lipid

concentrations compared with a high-fat (mainly unsaturated) diet.

 

However, much of the controversy between advocates and detractors of

dietary carbohydrate can be settled by taking into account dietary

*fiber*.

 

Several studies have shown that the adverse metabolic effects of

high-carbohydrate diets are neutralized when *fiber* and

carbohydrate

are *increased* " simultaneously " in the diet for diabetic patients.

 

In particular, these studies demonstrated that a

high-carbohydrate/high-fiber diet significantly improves blood

glucose

control and reduces plasma cholesterol levels in diabetic patients

compared with a low-carbohydrate/low-fiber diet.

 

 

In addition, a high-carbohydrate/high-fiber diet does not increase

plasma insulin and triglyceride concentrations, despite the higher

consumption of carbohydrates.

 

Unfortunately, dietary fiber represents a heterogenous category, and

there is still much to understand as to which foods should be

preferred to maximize the metabolic effects of fiber.

 

There are indications that only " water-soluble " fiber is active on

plasma glucose and lipoprotein metabolism in humans.

 

Therefore, in practice, the consumption of dried cooked

beans,legumes

 

and lentils, organic vegetables and

fruits--rich in water-soluble fiber--should be particularly

encouraged.

 

The mechanisms by which dietary fiber exerts its hypoglycemic and

hypolipidemic activities are unknown.

However, the ability of dietary fiber to retard food digestion and

nutrient absorption

certainly has an important " influence " on lipid and carbohydrate

metabolism.

 

The beneficial effects of high-fiber foods are also exerted by some

foods not particularly rich in fiber.

 

The fiber content and physical

form of the food can influence the accessibility of nutrients by

digestive enzymes, thus delaying digestion and absorption.

 

The identification of these foods with a low-glycemic response would

help enlarge the list of foods particularly suitable for diabetic

patients.

 

In conclusion, a diet low in cholesterol and saturated fat should be

recommended to all diabetic patients to prevent cardiovascular

disease.

 

A balanced increase in consumption of organic fiber-rich foods and

unsaturated

fat is the most rational way to replace foods rich in saturated fat

and cholesterol in the diabetic diet.

 

http://care.diabetesjournals.org/cgi/content/abstract/14/12/1115?

maxtoshow= & HITS\

 

=100 & hits=100 & RESULTFORMAT= & titleabstract=soluble+fiber & searchid=1019

506413568_1\

 

065 & stored_search= & FIRSTINDEX=0

 

JoAnn Guest

mrs-

Dieta-

http://www.geocities.com/mrsjoguest/Magnesium.html

 

 

 

Renal Failure & Lactic Acidosis in

Diabetic Woman Receiving *Metformin*(a Diabetic Drug)

,Rofecoxib

 

Acute Renal Failure and Lactic Acidosis Reported in Diabetic Woman

Receiving Metformin and Rofecoxib-British Journal of Anaesthesia

12/09/2003 By Keely S. Solomon, PhD

 

Doctors report that rofecoxib, a COX 2 inhibitor, may have

contributed to a case of acute renal failure and metformin-related

lactic acidosis.

 

COX 2 inhibitors are becoming increasingly popular for treatment of

inflammatory conditions due to a reduced incidence of

gastrointestinal side effects compared with traditional non-

steroidal

anti-inflammatory drugs (NSAIDS).

 

" What is less well appreciated is the role that the COX 2 inhibitors

may play in the development of renal failure, " writes Grant Price,

of

Victoria Hospital, Kirkcaldy, Fife, Scotland.

 

In the case report, Dr. Price describes a 58-year-old woman

diagnosed

with acute renal failure and lactic acidosis. The patient had a

medical history that included 10 years of type 2 diabetes mellitus

treated with diet modification and metformin.

 

According to Dr. Price, metformin therapy leads to an increase in

lactic acid production, and type B lactic acidosis has been

documented as a rare complication of this treatment. Moreover, any

renal impairment results in a reduced clearance of lactic acid,

which

can increase the risk for lactic acidosis in patients receiving

metformin.

 

" The COX 2 inhibitors may have an improved side-effect profile with

regard to gastric side effects, but their renal safety profile has

not been established, " cautions Dr. Price.

 

Based on the evidence from this case, he suggests that COX 2

inhibitors " can lead to a potentially disastrous outcome " in

patients receiving metformin.

Br J Anaesth 2003 Dec;91:6:909-10.

 

http://www.docguide.com/news/content.nsf/news/

645F9985BE5980A485256DF700508846

_________________

 

JoAnn Guest

mrsjoguest

DietaryTipsForHBP

http://www.geocities.com/mrsjoguest

 

 

 

 

 

 

 

The complete " Whole Body " Health line consists of the " AIM GARDEN TRIO "

Ask About Health Professional Support Series: AIM Barleygreen

 

" Wisdom of the Past, Food of the Future "

 

http://www.geocities.com/mrsjoguest/AIM.html

 

PLEASE READ THIS IMPORTANT DISCLAIMER

We have made every effort to ensure that the information included in these pages

is accurate. However, we make no guarantees nor can we assume any responsibility

for the accuracy, completeness, or usefulness of any information, product, or

process discussed.

 

 

 

 

 

 

 

 

 

SBC - Internet access at a great low price.

 

 

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