High Hormone Levels (Testosterone) Linked to Prostate Risks

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Health - Reuters

 

 

High Hormone Levels (Testosterone) Linked to Prostate Risk

 

Sun May 9,11:19 AM ET Add Health - Reuters to My

 

 

 

WASHINGTON (Reuters) - Men over 50 who have higher levels of testosterone have a

higher risk of prostate cancer, U.S. researchers reported on Sunday.

 

 

The findings may mean that men should be cautious about a new kind of treatment

called testosterone replacement therapy, being tested in older men who see a

decline in general health and vigor.

 

 

A study of more than 750 men showed those with the highest levels of free

testosterone in the blood were the most likely to have prostate cancer.

 

 

" Since testosterone replacement therapy increases the amount of free

testosterone in the blood, older men considering or receiving testosterone

replacement should be counseled as to the association until data from long-term

clinical trials becomes available, " said Dr. Kellogg Parsons, a urologist at

Johns Hopkins University who led the study, said in a statement.

 

 

The association between free testosterone and prostate cancer risk in older men

was not affected by height, weight, percent of body fat or muscle mass, Parsons

told a meeting of the American Urological Association in San Francisco.

 

 

A second study presented at the same conference found that obese men may be more

likely to see their prostate cancer come back after surgery.

 

 

Another Johns Hopkins team found that obese men are more likely than men with

normal weight to have high levels of prostate specific antigen, or PSA. PSA is

produced by prostate cells and is overproduced when the prostate becomes

cancerous.

 

 

" Our results show that moderately and severely obese men were at an increased

risk for high PSA levels after surgery and therefore are likely to have prostate

cancer recurrence, " said Dr. Stephen Freedland, who led the study.

 

 

His team studied 1,106 patients treated at five Veteran's Administration and

military hospitals across the country.

 

 

" Our findings add to the burgeoning list of chronic and deadly diseases

associated with obesity and underscore the importance of this major public

health problem, " Freedland said.

 

 

Obesity is also linked with pancreatic, breast and colon cancer, as well as

heart disease and diabetes.

 

 

Prostate cancer (news - web sites) affects 221,000 American men a year and kills

29,000.

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