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Diets high in folate linked with lower risk of prostate cancerThe April 2005 issue of the American Association for Cancer Research journal Cancer Epidemiology, Biomarkers & Prevention (http://cebp.aacrjournals.org/) published the findings of Italian researchers that a greater intake of folate is associated with a reduced risk of developing prostate cancer. Folate is the form of the B vitamin folic acid that naturally occurs in foods, particularly leafy green vegetables.

The current study utlized data from a case-control study of prostate cancer conducted between 1991 and 2002 in which 1,294 patients with prostate cancer were compared with 1,451 patients without cancer who were admitted to the same network of hospitals. Dietary information gathered from interviews during which the participants were asked about their intake of 78 different foods during the two years prior to their diagnosis or hospital admission was analyzed for folate and other nutritional levels.

Analysis of the data determined that folate intake was inversely related to prostate cancer risk. Men in the top one-fifth of folate consumption had a 34 percent lower risk of prostate cancer than that experienced by men whose folate intake was in the lowest fifth. This relathionship was consistent among men of all ages. When men whose intake of folate was high and alcohol consumption was low were compared to those whose intake of folate was low and alcohol consumption high, they were found to have a 54 percent lower risk of the disease

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