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Niacin

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Just came across this and thought you might be interested: Suzi

Niacin

Niacin is a B vitamin that is effective in lowering LDL, TC, TG and TC/HDL ratio. It also significantly raises HDL. All of these effects are desirable. The major advantage is that it is inexpensive and effective. The disadvantage is that it may cause skin itching and flushing after taking even moderate doses. This effect is reduced by taking a single aspirin 30 minutes prior to the niacin.

Liver injury is also possible as in the statins and monitoring of liver function is recommended. Crystalline niacin does not seem to cause liver injury, which is primarily associated with long acting or slow release forms of niacin. Recent products that release niacin slowly to decrease the flushing are Niaspan, Slo-Niacin, Niocor and Nicolar, but require regular monitoring of the liver to detect early damage. Niacin doses of 200-400 mg per day may be effective in lowering cholesterol levels, while dosages of up to 2000 mg per day may be used in serious cases of elevated lipids.

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