research on aspartame (methanol, formaldehyde) toxicity: Murray 3.21.4 rmforall

[Guest guest]

research on aspartame (methanol, formaldehyde) toxicity:

Murray 3.21.4 rmforall

 

Rich Murray, MA Room For All rmforall

1943 Otowi Road, Santa Fe, New Mexico 87505 USA 505-986-9103

 

[ aspartameNM/message/927

Donald Rumsfeld, 1977 head of Searle Corp., got aspartame FDA approval:

Turner: Murray 12.23.2 rmforall ]

 

aspartameNM/message/1039

three-page review: aspartame (methanol, formaldehyde) toxicity:

Murray 11.22.3 rmforall

 

aspartameNM/message/1026

brief aspartame review: formaldehyde toxicity: Murray 9.11.3 rmforall

 

aspartameNM/message/989 On 4.10.2003

the European Union Parliament voted 440 to 20 to approve sucralose,

limit cyclamates & reevaluate aspartame & stevia: Murray 4.12.3 rmforall

 

http://google.com gives 221,000 websites for " aspartame " , with the top

9 of 10 listings being anti-aspartame, while

http://groups.google.com finds on 700 MB of posts from 20 years of

Usenet groups, 83,800 posts, the top 10 being anti-aspartame.

 

http://news.google.com 28 recent aspartame items from 4500 sources.

http://www.AllTheWeb.com gives 291,700, the top 7 of 10 being

leading and very well informed volunteer anti-aspartame sites.

http://teoma.com/index.asp gives 85,700 websites, top 8 of 10 anti.

http://www.ncbi.nlm.nih.gov/PubMed lists 742 aspartame items.

 

aspartameNM/message/1025

aspartame & formaldehyde toxicity: Murray 9.9.3 rmforall

 

aspartameNM/messages

for 1060 posts in a public searchable archive 119 members

 

aspartame/messages 774 with 16,660 posts

 

aspartameNM/message/1047

Avoiding Hangover Hell 12.31.3 Mark Sherman, AP writer: Robert Swift, MD:

[formaldehyde from methanol in aspartame]: Murray 1.16.4 rmforall

 

aspartameNM/message/1048

hangovers from formaldehyde from methanol (aspartame?):

Schwarcz: Linsley: Murray 1.18.4

 

aspartameNM/message/1052

DMDC: Dimethyl dicarbonate 200mg/L in drinks adds methanol 98 mg/L

( becomes formaldehyde in body ): EU Scientific Committee on Foods 7.12.1:

Murray 1.22.4 rmforall

 

aspartameNM/message/1024

aspartame review: methanol, formaldehyde, formic acid toxicity:

Murray 9.5.3 rmforall

 

aspartameNM/message/910

formaldehyde & formic acid from methanol in aspartame:

Murray: 12.9.2 rmforall

 

It is certain that high levels of aspartame use, above 2 liters daily

for months and years, must lead to chronic formaldehyde-formic acid

toxicity, since 11% of aspartame (1,120 mg in 2L diet soda, 5.6 12-oz

cans) is 123 mg methanol (wood alcohol), immediately released into the

body after drinking (unlike the large levels of methanol locked up in

molecules inside many fruits), then quickly transformed into

formaldehyde, which in turn becomes formic acid, both of which in

time are partially eliminated as carbon dioxide and water.

 

However, about 30% of the methanol remains in the body as cumulative

durable toxic metabolites of formaldehyde and formic acid-- 37 mg daily,

a gram every month. [Metabolism of aspartame in monkeys.

Oppermann JA, Muldoon E, Ranney RE.

J. Nutrition 1973 Oct; 103(10): 1454-1459.]

If 10% of the methanol is retained as formaldehyde, that would give 12

mg daily formaldehyde accumulation, about 60 times more than the 0.2 mg

from 10% retention of the 2 mg EPA daily limit for formaldehyde in water.

 

Bear in mind that the EPA limit for formaldehyde in drinking water is

1 ppm, or 2 mg daily for a typical daily consumption of 2 L of water.

 

aspartameNM/message/835

RTM: ATSDR: EPA limit 1 ppm formaldehyde in drinking water July 1999

5.30.2 rmforall

 

This long-term low-level chronic toxic exposure leads to typical

patterns of increasingly severe complex symptoms, starting with

headache, fatigue, joint pain, irritability, memory loss, and

leading to vision and eye problems, and even seizures. In many cases

there is addiction. Probably there are immune system disorders, with a

hypersensitivity to these toxins and other chemicals.

 

aspartameNM/message/872

immune system reactions due to formaldehyde from the 11% methanol in

aspartame: Thrasher: Tephly: Monte: Murray 9.27.2 rmforall

 

J. Nutrition 1973 Oct; 103(10): 1454-1459.

Metabolism of aspartame in monkeys.

Oppermann JA, Muldoon E, Ranney RE.

Dept. of Biochemistry, Searle Laboratories,

Division of G.D. Searle and Co. Box 5110, Chicago, IL 60680

They found that about 70% of the radioactive methanol in aspartame put

into the stomachs of 3 to 7 kg monkeys was eliminated within 8 hours,

with little additional elimination, as carbon dioxide in exhaled air

and as water in the urine. They did not mention

that this meant that about 30% of the methanol must transform

into formaldehyde and then into formic acid, both of which must remain

as toxic products in all parts of the body. They did not report any

studies on the distribution of radioactivity in body tissues, except

that blood plasma proteins after 4 days held 4% of the initial

methanol. This study did not monitor long-term use of aspartame.

 

The low oral dose of aspartame and for methanol was 0.068 mmol/kg,

about 1 part per million [ppm] of the acute toxicity level of 2,000

mg/kg, 67,000 mmol/kg, used by McMartin (1979). Two L daily use of

diet soda provides 123 mg methanol, 2 mg/kg for a 60 kg person, a dose

of 67 mmole/kg, a thousand times more than the dose in this study.

By eight hours excretion of the dose in air and urine had leveled off

at 67.1 +-2.1% as CO2 in the exhaled air and 1.57+-0.32% in the urine,

so 68.7 % was excreted, and 31.3% was retained. [This data is the

average of 4 monkeys.]

 

aspartameNM/message/915

formaldehyde toxicity: Thrasher & Kilburn: Shaham: EPA: Gold: Murray:

Wilson: CIIN: 12.12.2 rmforall

 

Thrasher (2001): " The major difference is that the Japanese demonstrated

the incorporation of FA and its metabolites into the placenta and fetus.

The quantity of radioactivity remaining in maternal and fetal tissues

at 48 hours was 26.9% of the administered dose. " [Ref. 14-16]

 

Arch Environ Health 2001 Jul-Aug; 56(4): 300-11.

Embryo toxicity and teratogenicity of formaldehyde. [100 references]

Thrasher JD, Kilburn KH.

Sam-1 Trust, Alto, New Mexico, USA.

http://www.drthrasher.org/formaldehyde_embryo_toxicity.html full text

 

http://www.drthrasher.org/formaldehyde_1990.html full text Jack Dwayne

Thrasher, Alan Broughton, Roberta Madison. Immune activation and

autoantibodies in humans with long-term inhalation exposure to formaldehyde.

Archives of Environmental Health. 1990; 45: 217-223. " Immune activation,

autoantibodies, and anti-HCHO-HSA antibodies are associated with long-term

formaldehyde inhalation. " PMID: 2400243

 

Confirming evidence and a general theory are given by Pall (2002):

aspartameNM/message/909

testable theory of MCS type diseases, vicious cycle of nitric oxide &

peroxynitrite: MSG: formaldehyde-methanol-aspartame:

Martin L. Pall: Murray: 12.9.2 rmforall

 

aspartameNM/message/1055

hormesis: possible benefits of low-level aspartame (methanol, formaldehyde)

use: Calabrese: Soffritti: Murray 3.11.4

 

aspartameNM/message/1056

disorders of NMDA glutamate receptors in brain range from high activity

(MCS, CF, PTSD, FM, from carbon monoxide or formaldehyde (methanol,

aspartame)-- Pall)

to low activity (schizophrenia-- Coyle, Goff, Javitts):

Murray 3.13.4 rmforall

 

aspartameNM/message/946

Functional Therapeutics in Neurodegenerative Disease Part 1/2:

Perlmutter 7.15.99: Murray 1.10.3 rmforall

 

aspartameNM/message/97

Lancet website aspartame letter 7.29.99:

Excitotoxins 1999 Part 1/3 Blaylock: Murray 1.14.0 rmforall

The Medical Sentinel Journal 1999 Fall; (95 references)

http://www.dorway.com/blayenn.html

aspartame (methanol, formaldehyde) toxicity: Murray 1.1.4 rmforall

 

aspartameNM/message/1034

Brain cell damage from amino acid isolates (aspartame releases

phenylalanine, aspartate, methanol [formaldehyde, formic acid] Bowen &

Evangelista May 6 2002: Murray 11.10.3 rmforall

 

http://www.aspartame.ca/Brain%20Cell%20Damage.pdf

Brain cell damage from amino acid isolates 5.6.2 41 references

detailed 22 page review by James D. Bowen, MD and Arthur M. Evangelista,

former FDA Investigator orwilly

 

aspartameNM/message/628

Rich Murray: Professional House Doctors: Singer: EPA: CPSC:

formaldehyde toxicity 6.10.1 rmforall

 

aspartameNM/message/782

RTM: Smith, Terpening, Schmidt, Gums:

full text: aspartame, MSG, fibromyalgia 1.17.2 rmforall

Jerry D Smith, Chris M Terpening, Siegfried OF Schmidt, and John G Gums

Relief of Fibromyalgia Symptoms Following

Discontinuation of Dietary Excitotoxins.

The Annals of Pharmacotherapy 2001; 35(6): 702-706.

Malcolm Randall Veterans Affairs Medical Center, Gainesville, FL, USA.

BACKGROUND: Fibromyalgia is a common rheumatologic disorder that is

often difficult to treat effectively.

CASE SUMMARY: Four patients diagnosed with fibromyalgia syndrome

for two to 17 years are described.

All had undergone multiple treatment

modalities with limited success. All had complete, or nearly complete,

resolution of their symptoms within months after eliminating monosodium

glutamate (MSG) or MSG plus aspartame from their diet.

All patients were women with multiple comorbidities

prior to elimination of MSG.

All have had recurrence of symptoms whenever MSG is ingested.

 

Siegfried O. Schmidt, MD Asst. Clinical Prof. siggy

Community Health and Family Medicine, U. Florida, Gainesville, FL

Shands Hospital West Oak Clinic Gainesville, FL 32608-3629

352-376-5071

 

Debbie J. Hypes painfreeliving 304-872-4141 (Case # 1 of 4)

P.O Box 25 Lookout, WV 25868-0025 She has about 1,000 on her local

mailing list, and has been a volunteer activist since 1997. Her guide

first came out in 1997: http://www.Pain-Free-Living.net

" The Food Plan: How To Do It " $ 5 by mail, free by email.

Her sister Darlene, now 47, cured her own severe fibromyalgia in 1995

by using an elimination diet, and then Debbie also cured herself by

1997. Their doctor, Siegfried Schmidt, paying attention, tried it on

two more patients, who got well, and are his third and fourth cases.

 

aspartameNM/message/846

RTM: aspartame in Merck Maxalt-MLT worsens migraine,

AstraZeneca Zomig, Eli Lilly Zyprexa,

J & J Merck Pepcid AC (Famotidine 10mg) Chewable Tab,

Pfizer Cool Mint Listerine Pocketpaks 7.16.2 rmforall

Migraine MLT-Down: an unusual presentation of migraine

in patients with aspartame-triggered headaches.

Newman LC, Lipton RB Headache 2001 Oct; 41(9): 899-901.

[Merck 10-mg Maxalt-MLT, for migraine, has 3.75 mg aspartame,

while 12 oz diet soda has 200 mg.]

Headache Institute, St. Lukes-Roosevelt Hospital Center, New York, NY

Department of Neurology newmanache

Albert Einstein College of Medicine, Bronx, NY

Innovative Medical Research RLipton

 

aspartameNM/message/855

RTM: Blumenthall & Vance:

aspartame chewing gum headaches Nov 1997 7.28.2 rmforall

Harvey J. Blumenthal, MD, Dwight A Vance, RPh

Chewing Gum Headaches.

Headache 1997 Nov-Dec; 37(10): 665-6.

Department of Neurology, University of Oklahoma College of Medicine,

Tulsa, USA. neurotulsa

Aspartame, a popular dietetic sweetener, may provoke headache in some

susceptible individuals. Herein, we describe three cases of young women

with migraine who reported their headaches could be provoked by chewing

gum sweetened with aspartame. [6-8 mg aspartame per stick chewing gum]

 

aspartameNM/message/925

aspartame puts formaldehyde adducts into tissues, Part 1/2

full text, Trocho & Alemany 6.26.98: Murray 12.22.2 rmforall

 

aspartameNM/message/926

aspartame puts formaldehyde adducts into tissues, Part 2/2

full text, Trocho & Alemany 6.26.98: Murray 12.22.2 rmforall

 

http://ww.presidiotex.com/barcelona/index.html

Trocho C, Pardo R, Rafecas I, Virgili J, Remesar X,

Fernandez-Lopez JA, Alemany M [ " Trok-ho " ]

Formaldehyde derived from dietary aspartame binds to tissue

components in vivo. Life Sci 1998 Jun 26; 63(5): 337-49.

Departament de Bioquimica i Biologia Molecular, Facultat de Biologia,

Universitat de Barcelona, Spain.

http://www.presidiotex.com/barcelona/index.html

Maria Alemany, PhD (male) alemany

 

aspartameNM/message/864

Murray: Butchko, Tephly, McMartin: Alemany: aspartame formaldehyde

adducts in rats 9.8.2 rmforall

Prof. Alemany vigorously affirms the validity of the Trocho study

against criticism:

Butchko, HH et al [24 authors], Aspartame: review of safety.

Regul. Toxicol. Pharmacol. 2002 April 1; 35 (2 Pt 2): S1-93, review

available for $35, [an industry paid organ]. Butchko:

" When all the research on aspartame, including evaluations in both the

premarketing and postmarketing periods, is examined as a whole, it is

clear that aspartame is safe, and there are no unresolved questions

regarding its safety under conditions of intended use. "

[ They repeatedly pass on the ageless industry deceit that the methanol

in fruits and vegetables is as as biochemically available as that in

aspartame-- see the 1984 rebuttal by Monte, below.

In the same report, Schiffman concludes on page S49, not citing any

research after 1997, " Thus, the weight of the scientific evidence

indicates that aspartame does not cause headache. "

Dr. Susan S. Schiffman, Dept. of Psychiatry, Duke University

sss 919-684-3303, 660-5657

aspartameNM/message/864

Murray: Butchko, Tephly, McMartin: Alemany: aspartame formaldehyde

adducts in rats 9.8.2 rmforall ]

 

aspartameNM/message/911

RTP ties to industry criticized by CSPI: Murray: 12.9.2 rmforall

 

aspartameNM/message/622

Rich Murray: Gold: Koehler: Walton: Van Den Eeden: Leon:

aspartame toxicity 6.4.1 rmforall four double-blind studies

 

aspartameNM/message/623

Rich Murray: Simmons: Gold: Schiffman: Spiers:

aspartame toxicity 6.4.1 rmforall two double-blind studies

 

aspartameNM/message/1045

http://www.holisticmed.com/aspartame/scf2002-response.htm

Mark Gold exhaustively critiques European Commission Scientific

Committee on Food re aspartame (12.4.2): 59 pages, 230 references

 

aspartameNM/message/957

safety of aspartame Part 1/2 12.4.2: EC HCPD-G SCF:

Murray 1.12.3 rmforall EU Scientific Committee on Food, a whitewash

 

aspartameNM/message/1018

aspartame toxicity coverup increases danger of corporate meltdown:

Michael C. Carakostas of Coca-Cola: Murray 8.11.3 rmforall

http://www.isrtp.org/new_members/members1.htm

The International Society of Regulatory Toxicology and Pharmacology

Carakostas, Michael C., DVM, PhD Director/Scientific & Regulatory

Affairs The Coca-Cola Company PO Drawer 1734 Atlanta, GA 30301

T. 404/676-4234 F. 404/676-7166 E-mail: mcarakostas

http://www2.coca-cola.com/ourcompany/columns_aspartame.html [photo]

Aspartame: The world agrees it's safe By Michael Carakostas, DVM, PhD, Scientific and Regulatory Affairs, Coca-Cola

 

It is commendable that Carakostas mentions the core problem, albeit

disparagingly: " During digestion, aspartame yields a very small amount

of methanol-- as do many other food substances. The body converts this

methanol to formaldehyde, which is instantly converted to formate.

Formate is quickly eliminated as carbon dioxide and water. "

 

Plenty of evidence in the mainstream scientific literature since 1973

shows that as much as 30% of the formaldehyde is retained in the body as

toxic, cumulative adducts to the DNA, RNA, and proteins in all cells and

tissues, leading to pointed reports by informed doctors and experts.

Clearly, there are no safe levels for chronic, low-level formaldehyde

exposure. If just 10% of the methanol from six cans of diet soda is

retained in the body as toxic products of formaldehyde and formic acid,

that is sixty times the EPA limit for allowable formaldehyde from daily

drinking water.

 

aspartameNM/message/1016

President Bush & formaldehyde (aspartame) toxicity: Ramazzini Foundation

carcinogenicity results Dec 2002: Soffritti: Murray 8.3.3 rmforall

 

p. 88 " The sweetening agent aspartame hydrolyzes in the gastrointestinal

tract to become free methyl alcohol, which is metabolized in the liver

to formaldehyde, formic acid, and CO2. (11) "

Medinsky MA & Dorman DC. 1994; Assessing risks of low-level

methanol exposure. CIIT Act. 14: 1-7.

 

Ann N Y Acad Sci. 2002 Dec; 982: 87-105.

Results of long-term experimental studies on the carcinogenicity of

formaldehyde and acetaldehyde in rats.

Soffritti M, Belpoggi F, Lambertin L, Lauriola M, Padovani M, Maltoni C.

Cancer Research Center, European Ramazzini Foundation for Oncology and

Environmental Sciences, Bologna, Italy. crcfr

 

Formaldehyde was administered for 104 weeks in drinking water supplied

ad libitum at concentrations of 1500, 1000, 500, 100, 50, 10, or 0 mg/L

to groups of 50 male and 50 female Sprague-Dawley rats beginning at

seven weeks of age.

Control animals (100 males and 100 females) received tap water only.

Acetaldehyde was administered to 50 male and 50 female Sprague-Dawley

rats beginning at six weeks of age at concentrations of 2,500, 1,500,

500, 250, 50, or 0 mg/L.

Animals were kept under observation until spontaneous death.

Formaldehyde and acetaldehyde were found to produce an increase in total

malignant tumors in the treated groups and showed specific carcinogenic

effects on various organs and tissues. PMID: 12562630

 

Surely the authors deliberately emphasized that aspartame is well-known

to be a source of formaldehyde, which is an extremely potent, cumulative

toxin, with complex, multiple effects on all tissues and organs.

 

This is even more significant, considering that they have already tested

aspartame, but not yet released the results:

 

p. 29-32 Table 1: The Ramazzinni Foundation Cancer Program

Project of [200] Long-Term Carcinogenicity Bioassays: Agents Studied

 

No. No. of Bioassays Species No. Route of Exposure

108. " Coca-Cola " 4 Rat 1,999 Ingestion, Transplantal Route

109. " Pepsi-Cola " 1 Rat 400 Ingestion

110. Sucrose 1 Rat 400 Ingestion

111. Caffeine 1 Rat 800 Ingestion

112. Aspartame 1 Rat 1,800 Ingestion

 

http://members.nyas.org/events/conference/conf_02_0429.html

Soffritti said that Coca-Cola showed no carcinogenicity.

 

It may be time to disclose these important aspartame results.

 

aspartameNM/message/934

24 recent formaldehyde toxicity [Comet assay] reports:

Murray 12.31.2 rmforall

 

aspartameNM/message/935

Comet assay finds DNA damage from sucralose, cyclamate, saccharin in

mice: Sasaki YF & Tsuda S Aug 2002: Murray 1.1.3 rmforall

[Also borderline evidence, in this pilot study of 39 food additives,

using test groups of 4 mice, for DNA damage from for stomach, colon,

liver, bladder, and lung 3 hr after oral dose of 2000 mg/kg aspartame--

a very high dose.]

 

aspartameNM/message/961

genotoxins, Comet assay in mice: Ace-K, stevia fine; aspartame poor;

sucralose, cyclamate, saccharin bad: Y.F. Sasaki Aug 2002:

Murray 1.27.3 rmforall [A detailed look at the data]

 

http://www.dorway.com/tldaddic.html 5-page review

Roberts HJ Aspartame (NutraSweet) addiction.

Townsend Letter 2000 Jan; HJRobertsMD

http://www.sunsentpress.com/ sunsentpress

Sunshine Sentinel Press P.O.Box 17799 West Palm Beach, FL 33416

800-814-9800 561-588-7628 561-547-8008 fax

 

aspartameNM/message/669

1038-page medical text " Aspartame Disease: An Ignored Epidemic "

published May 30 2001 $ 60.00 postpaid data from 1200 cases

available at http://www.amazon.com

over 600 references from standard medical research

 

http://www.dorway.com David O. Rietz over 12,000 print pages

Mission-Possible-USA Betty Martini 770-242-2599

Bettym19 dorietz

http://www.dorway.com/asprlink.html many links

http://www.dorway.com/nslawsuit.txt Jeff Martin, Attorney

http://www.dorway.com/doctors.txt

What many informed doctors are saying/have said about aspartame

 

http://www.HolisticMed.com/aspartame 603-225-2100

Aspartame Toxicity Information Center Mark D. Gold

mgold 12 East Side Drive #2-18 Concord, NH 03301

http://www.holisticmed.com/aspartame/abuse/methanol.html

" Scientific Abuse in Aspartame Research "

 

Aspartame Consumer Safety Network and Pilot Hotline [1987-2001]

Mary Nash Stoddard, Founder & President

P.O. Box 780634 Dallas, TX 75378 .

214-352-4268 marystod

http://web2.airmail.net/marystod/index.html

http://web2.airmail.net/marystod/espanol.htm

Toxicology Sourcebook: " Deadly Deception: Story of Aspartame "

 

aspartameNM/message/802

RTM: 700.club.com: CBN:

Totheroh & Robertson: aspartame expose 2.13.2 rmforall

 

aspartameNM/message/805

RTM: Ive: UK Daily Mirror Magazine: aspartame toxicity 2.18.2 rmforall

 

aspartameNM/message/857

RTM: www.dorway.com: original documents and long reviews of flaws in

aspartame toxicity research 7.31.2 rmforall

 

http://www.dorway.com/upipart1.txt

aspartameNM/message/262

aspartame expose 96K Oct 1987 Part 1/3: Gregory Gordon, UPI reporter:

Murray 7.10.0 rmforall

 

http://www.dorway.com/enclosur.html

aspartameNM/message/53

aspartame history Part 1/4 1964-1976: Gold: Murray 11.6.9: rmforall

 

aspartameNM/message/927

Rumsfeld, 1977 head of Searle Corp., got aspartame FDA approval:

Turner: Murray 12.23.2 rmforall

 

aspartameNM/message/928

revolving door, Monsanto, FDA, EPA: NGIN: Murray 12.23.2 rmforall

 

aspartameNM/message/957

safety of aspartame Part 1/2 12.4.2: EC HCPD-G SCF:

Murray 1.12.3 rmforall EU Scientific Committee on Food

 

aspartameNM/message/841

RTM: Merisant Co., MSD Capital, Dell Computer Corp., NutraSweet Co.,

JW Childs Assc.: aspartame-neotame toxicity 7.10.2 rmforall

 

aspartameNM/message/876

hyperthyroidism (Graves disease) in George and Barbara Bush, 1991--

aspartame toxicity? Roberts 1997: Murray 10.9.2 rmforall

 

aspartameNM/message/874

re " dry drunk " : Bisbort: danger to President Bush from aspartame

toxicity: Murray: 2.24.2 9.29.2 rmforall

 

Many scientific studies and case histories report: * headaches

* many body and joint pains (or burning, tingling, tremors, twitching,

spasms, cramps, stiffness, numbness, difficulty swallowing)

* fever, fatigue, swollen glands * " mind fog " , " feel unreal " , poor

memory, confusion, anxiety, irritability, depression, mania, insomnia,

dizziness, slurred speech, sexual problems, poor vision, hearing

(deafness, tinnitus), or taste * red face, itching, rashes, hair loss,

burning eyes or throat, dry eyes or mouth, mouth sores, burning tongue

* obesity, bloating, edema, anorexia, poor appetite or excessive hunger

or thirst * breathing problems, shortness of breath * nausea,

diarrhea or constipation * coldness * sweating * racing heart, low or

high blood pressure, erratic blood sugar levels * hypothryroidism or

hyperthyroidism * seizures * birth defects * brain cancers

* addiction * aggrivates diabetes, autism, allergies, lupus, ADHD,

fibromyalgia, chronic fatigue syndrome, multiple chemical sensitivity,

multiple sclerosis, and interstitial cystitis (bladder pain).

***********************************************************

 

http://www.readthelabel.org.uk/ Additives Survivors' Network (UK)

Geoff Brewer <geoffbrewer

http://www.chem.ox.ac.uk/mom/aspartame/aspartame.html

http://www.chm.bris.ac.uk/webprojects2000/srogers/sarah.html

Sarah Rogers <sr8442

http://www.react.ie/Health/Nutrition/Aspartame.htm Ireland

http://members.tripod.com/~mission_possible/scotland_branch.html

http://www.aspartame.ca/indexa.html John T. Linnell <admin

http://www.cybernaute.com/earthconcert2000/AspartaMalcache.htm

http://www.fedupwithfoodadditives.info/ Australia FAILSAFE diet

http://www.bradymax.com/nzaa/ New Zealand

http://www.reseauproteus.net/therapies/nutritio/aspartame.htm France

http://ww2.grn.es/avalls/aspa1.htm Spain

http://www.geocities.com/HotSprings/Falls/8669/ Brazil

http://www.phd.com.br/aspartame.htm

http://hem.passagen.se/mission.possible.sweden/

http://home.online.no/~dusan/foods/aspartame.html Norway

http://www.ostara.org/aspartam/#menue Germany

http://www.aspartaam.nl/info/product.html Holland, in Dutch

http://www.laleva.org/ <archimede Italy 9 languages

http://www.laleva.cc/alimenti/alimenti.html aspartame vs stevia 4.17.03

http://users.westnet.gr/~cgian/aspartame.htm Greece

http://www.cseindia.org/html/cola-indepth/index.htm India

***********************************************************

 

aspartameNM/message/870

Aspartame: Methanol and the Public Interest 1984:

Monte: Murray 9.23.2 rmforall

 

Dr. Woodrow C. Monte Aspartame: methanol, and the public health.

Journal of Applied Nutrition 1984; 36 (1): 42-54.

(62 references) Professsor of Food Science [retired 1992]

Arizona State University, Tempe, Arizona 85287 woodymonte

The methanol from 2 L of diet soda, 5.6 12-oz cans, 20 mg/can, is

112 mg, 10% of the aspartame. The EPA limit for water is 7.8 mg daily

for methanol (wood alcohol), a deadly cumulative poison. Many users

drink 1-2 L daily. The reported symptoms are entirely consistent

with chronic methanol toxicity. (Fresh orange juice has 34 mg/L, but,

like all juices, has 16 times more ethanol, which strongly protects

against methanol.)

 

" Fruit and vegetables contain pectin with variable methyl ester

content. However, the human has no digestive enzymes for pectin (6, 25)

particularly the pectin esterase required

for its hydrolysis to methanol (26).

 

Fermentation in the gut may cause disappearance of pectin (6) but the

production of free methanol is not guaranteed by fermentation (3). In

fact, bacteria in the colon probably reduce methanol directly to formic

acid or carbon dioxide (6) (aspartame is completely absorbed before

reaching the colon). Heating of pectins has been shown to cause

virtually no demethoxylation; even temperatures of 120 deg C produced

only traces of methanol (3). Methanol evolved during cooking of high

pectin foods (7) has been accounted for in the volatile fraction during

boiling and is quickly lost to the atmosphere (49). Entrapment of these

volatiles probably accounts for the elevation in methanol levels of certain

fruits and vegetable products during canning (31, 33). "

 

Recent research [see links at end of post] supports his focus on the

methanol to formaldehyde toxic process:

 

" The United States Environmental Protection Agency in their Multimedia

Environmental Goals for Environmental Assessment recommends a minimum

acute toxicity concentration of methanol in drinking water at 3.9 parts

per million, with a recommended limit of consumption below 7.8 mg/day

(8). This report clearly indicates that methanol:

 

" ...is considered a cumulative poison due to the low rate of excretion

once it is absorbed. In the body, methanol is oxidized to formaldehyde

and formic acid; both of these metabolites are toxic. " (8)...

 

Recently the toxic role of formaldehyde (in methanol toxicity) has been

questioned (34). No skeptic can overlook the fact that, metabolically,

formaldehyde must be formed as an intermediate to formic acid

production (54).

 

Formaldehyde has a high reactivity which may be why it has not been

found in humans or other primates during methanol posisioning (59)....

 

If formaldehyde is produced from methanol and does have a reasonable

half life within certain cells in the poisoned organism the chronic

toxicological ramifications could be grave.

 

Formaldehyde is a known carcinogen (57) producing squanous-cell

carcinomas by inhalation exposure in experimental animals (22). The

available epidemiological studies do not provide adequate data for

assessing the carcinogenicity of formaldehyde in man (22, 24, 57).

 

However, reaction of formaldehyde with deoxyribonucleic acid (DNA)

has resulted in irreversible denaturation that could interfere with DNA

replication and result in mutation (37)... "

 

http://www.dorway.com/barua.html

Dr. J. Barua (ophthalmic surgeon), Dr. Arun Bal (surgeon)

Emerging facts about aspartame.

Journal Of The Diabetic Association Of India 1995; 35 (4):

(79 references) barua

" ...the total amount of methanol absorbed will be approximately

10% of aspartame ingested. An EPA assessment of methanol states

that methanol, 'is considered a cumulative poison due to the low rate

of excretion once it is absorbed. The absorbed methanol is then

slowly converted to formaldehyde...' "

" Reaction of formaldehyde with DNA has been observed,

by spectrophotometry and electron microscopy, to result in

irreversible denaturation. " " DKP [from aspartame] has been implicated

in the occurence of brain tumors. "

************************************************************

 

aspartameNM/message/939

aspartame (aspartic acid, phenylalanine) binding to DNA:

Karikas July 1998: Murray 1.5.3 rmforall

Karikas GA, Schulpis KH, Reclos GJ, Kokotos G

Measurement of molecular interaction of aspartame and

its metabolites with DNA. Clin Biochem 1998 Jul; 31(5): 405-7.

Dept. of Chemistry, University of Athens, Greece

http://www.chem.uoa.gr gkokotos

" K.H. Schulpis " <inchildh " G.J. Reclos " <reklos

 

aspartameNM/message/960

aspartame & MSG: possible role in autoimmune hepatitis:

Prandota Jan 2003: Murray 1.15.3 rmforall

Roberts, Hyman J., 1924- ,

Useful insights for diagnosis, treatment and public heath: an updated

anthology of original research, 2002, 798 pages,

Palm Beach Institute for Medical Research, Inc.

P.O. Box 17799, West Palm Beach, FL 33416

fax 561-547-8008 dr.roberts

aspartame disease pages 627-685, 778-780

 

aspartameNM/message/859

RTM: Roberts: the life work of a brilliant clinician:

aspartame toxicity 8.2.2 rmforall

 

aspartameNM/message/790

RTM: Moseley:

review Roberts " Aspartame Disease: An Ignored Epidemic " 2.7.2 rmforall

 

aspartameNM/message/858

RTM: Samuels: Strong: Roberts: Gold: flaws in double-blind studies re

aspartame and MSG toxicity 8.1.2 rmforall

 

" Survey of aspartame studies: correlation of outcome and funding

sources, " 1998, unpublished: http://www.dorway.com/peerrev.html

Walton found 166 separate published studies in the peer reviewed

medical literature, which had relevance for questions of human safety.

The 74 studies funded by industry all (100%) attested to aspartame's

safety, whereas of the 92 non-industry funded studies, 84 (91%)

identified a problem. Six of the seven non-industry funded studies

that were favorable to aspartame safety were from the FDA, which

has a public record that shows a strong pro-industry bias.

Ralph G. Walton, MD, Prof. of Clinical Psychology, Northeastern Ohio

Universities, College of Medicine, Dept. of Psychiatry, Youngstown,

OH 44501, Chairman, The Center for Behavioral Medicine,

Northside Medical Center, 500 Gypsy Lane, P.O. Box 240 Youngstown,

OH 44501 330-740-3621 rwalton193

http://www.neoucom.edu/DEPTS/Psychiatry/walton.htm

 

aspartameNM/message/938

aspartame harms mice brain cells: Hetle & Eltervaag: 2001 thesis

abstract: Sonnewald 1995 study, full text: Murray 1.5.3 rmforall

 

aspartameNM/message/346

WebMD: Barclay: Barth:

survey shows aspartame hurts memory in students 11.9.00

http://www.psy.tcu.edu/psy/barth.htm

Timothy M. Barth Department of Psychology t.barth

Texas Christian University TCU Box 298920 Fort Worth, TX 76129

Chairman, Physiological Psychology 817-921-7410

 

aspartameNM/message/760

Kovatsi L, Tsouggas M

The effect of oral aspartame administration on the

balance of magnesium in the rat.

Magnes Res 2001 Sep;14(3): 189-94.

Laboratory of Forensic Medicine & Toxicology, Faculty of Medicine

Aristotle University of Thessaloniki, Greece kovatsi

 

aspartameNM/message/943

aspartame, cell phones, brain cancer July 1999 Hardell:

Murray 1.9.3 rmforall

http://www.medscape.com/MedGenMed/braintumors

Lennart Hardell, M.D., PhD, in 1999 reported in Sweden that both

cell phone use and heavy aspartame use correlate with increased

brain cancers lennart.hardell +46 19 602 15 46

 

aspartameNM/message/31

Murray: Wurtman: aspartame & seizures 11.9.85 10.30.99

Wurtman RJ Aspartame: possible effect on seizure susceptibility.

Lancet 1985 Nov 9; 2(8463): 1060.

Richard J. Wurtman, Ph.D. dick 617-253-3091

Professor of Neuroscience

Prof. of Health Sciences and Technology

Massachusetts Institute of Technlogy Cambridge, Mass. 02139

 

aspartameNM/message/32

Murray: Drake: aspartame & panic attacks 9.13.86 10.30.99 rmforall

Miles E. Drake, MD

Panic attacks and excessive aspartame ingestion.

Lancet 1986 Sep 13; 2(8507): 631.

Department of Neurology and Psychiatry,

Ohio State University Medical Center, Columbus, Ohio 43210, USA

 

http://www.truthinlabeling.org/ Truth in Labeling Campaign [MSG]

Adrienne Samuels, PhD The toxicity/safety of processed

free glutamic acid (MSG): a study in suppression of information.

Accountability in Research 1999; 6: 259-310. 52-page review

P.O. Box 2532 Darien, Illinois 60561

858-481-9333 adandjack

 

http://www.msgmyth.com/ Debby Anglesey <avenger

Battling the " MSG Myth " , A Survival Guide and Cookbook - $19.00

P.O. Box 895 Richland, WA 99352 509-735-3397

 

Russell L. Blaylock, MD 601-982-1175 Madison, Mississippi

" Excitotoxins: The Taste that Kills " , 1977, 298 p., 493 references.

" Health and Nutrition Secrets that can save your life " , 2002, 459 p.,

558 + 30 references, $ 30 http://www.russellblaylockmd.com/

 

George R. Schwartz, MD " In Bad Taste: The MSG Syndrome " , 1988

http://www.healthpress.com/ goodbooks

PO Box 37470 Albuquerque, NM 87176 505-888-1394

Kathleen Frazier, Publisher

 

aspartameNM/message/841

RTM: Merisant Co., MSD Capital, Dell Computer Corp., NutraSweet Co.,

JW Childs Assc.: aspartame-neotame toxicity 7.10.2 rmforall

****************************************************************

 

http://www.vegsource.com extensive vegan information

http://www.vegsource.com/articles/kradjian_milk.htm

Robert Kradjian MD Discusses Milk

 

aspartameNM/message/971

Joel Fuhrman critique of Atkins diet in " Eat To Live " :

Murray 3.1.3 rmforall

 

Substitute stevia (at health food stores).

Avoid all products with aspartame and MSG. Gradually reduce alcohol,

caffeine (coffee, cocoa, and teas), meat, fish, eggs, milk, butter, and

cheese, food additives and colors, fluoride, city water. Enjoy organic

rice, beans, nuts, almond butter, vegetables, fruits, with modest use of

soy products and sprouted grain breads, flax seed and olive oils, vitamins

and minerals, 4-8 1,000 mg fish oil capsules, and fill your jugs with

deionized water.

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