Guest guest Posted March 5, 2004 Report Share Posted March 5, 2004 CJD Prions a Surgery Risk? So much for uninfected steaks!!! Joan Stephenson, PhD JAMA. 2003;290:3057. Researchers from Switzerland have discovered that prions, the hardy infectious proteins responsible for Creuzfeldt-Jakob disease (CJD), can be detected in skeletal muscle of affected patients. This finding, they said, suggests that surgical equipment used on patients with CJD could subsequently transmit the virus to others because the sterilization procedures routinely used for surgical implements do not destroy prions (N Engl J Med. 2003;349:1812-1820). Using an extremely sensitive prion detection method, the researchers examined brain tissue and extraneural organs of 36 patients with sporadic CJD. In addition to detecting prions in the brain tissue of all patients, they found prions in 10 of 28 spleen specimens and in 8 of 22 samples of skeletal muscles. Neurological examinations of patients in the prodromal stages of sporadic CJD often include electromyography and muscle biopsies. Thus, the researchers said, finding prions in skeletal muscle of patients with the disorder " reinforces calls for the use of single-use needle electrodes and of special protocols for the sterilization of surgical instruments used for biopsies. " The article this news story refers to was published in the New England Journal of Medicine, vol. 349, pages1812-1820 Joan Stephenson Joan Stephenson, PhD Editor, Medical News & Perspectives Journal of the American Medical Association (JAMA) 515 N. State St. Chicago, IL 60610 USA +1 312-464-2444 (tel) +1 312-464-5824 (fax) joan_stephenson http://jama.ama-assn.org/cgi/content/full/290/23/3057?etoc karl theis jr http://groups.msn.com/exposureofthetruth Search - Find what you’re looking for faster. Quote Link to comment Share on other sites More sharing options...
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