Fwd: [SSRI-Research] Effexor - Didn't they miss something???

[Guest guest]

Some of the so called " discontinuation symptoms " (see how they got around NOT

saying addiction or withdrawal? ) can last for a long long time and in some

cases may be permanent.

 

Heroin users can be detoxed and appear somewhat stable within 30 days. With some

of these SSRI's extanded withdrawal can last for years. How is that for

technical advancement? See how the progress in pharmacueticals can make drugs

more addictive and more problematic to stop and the process make them much more

profitable too as that will translate directly to the bottom line. Not only

that, the person withdrawing from an SSRI will usually experience a period of

severe mental illness including psychosis.

 

These side effects were from studies with very short term use. Most people take

these poisons for much longer periods of time and they have more severe problems

than stated here.

 

Frank

 

 

Insanity

Fri, 20 Feb 2004 22:20:26 -0500

[sSRI-Research] Effexor - Didn't they miss something???

 

[-- see notes inserted]

 

http://www.effexor.com/q/q10.asp

 

Discontinuing Effexor XR

 

When discontinuing Effexor XR after more than 1 week of therapy, it is generally

recommended

that the dose be tapered to minimize the risk of discontinuation symptoms.

Patients who have

received Effexor XR for 6 weeks or more should have their dose tapered over at

least a 2-week

period. In clinical trials with Effexor XR, tapering was achieved by reducing

the daily dose by

75 mg at 1 week intervals. Individualization of tapering may be necessary.

 

Discontinuation symptoms have been systematically evaluated in patients taking

venlafaxine, to

include prospective analyses of clinical trials in Generalized Anxiety Disorder

and retrospective

surveys of trials of major depressive disorder. Abrupt discontinuation or dose

reduction of

venlafaxine at various doses has been found to be associated with the appearance

of new

symptoms, the frequency of which increased with increased dose level and with

longer duration

of treatment.

 

Reported symptoms include agitation, anorexia, anxiety, confusion, coordination

impaired, diarrhea, dizziness, dry mouth, dysphoric mood, fasciculation,

fatigue, headaches,

hypomania, insomnia, nausea, nervousness, nightmares, seizures, sensory

disturbances

(including shock-like electrical sensations), somnolence, sweating, tinnitus,

tremor, vertigo, and

vomiting.

 

[-- Ahem... Didn't they miss something??? Where is the mention of akathesia and

how to treat it????]

 

It is therefore recommended that the dosage of Effexor XR be tapered gradually

and

the patient monitored. The period required for tapering may depend on the dose,

duration of

therapy and the individual patient. Discontinuation effects [ DON'T THEY MEAN -

DRUG WITHDRAWAL FROM ADDICTION????] are well known to occur with antidepressants

[REALLY? THIS IS WELL KNOWN? NEWS TO ME].

 

Switching Patients To or From a Monoamine Oxidase Inhibitor

 

At least 14 days [-- if the patient can live 14 days in withdrawal from

Effexor...without killing themself or someone else] should elapse between

discontinuation of an MAOI and initiation of therapy

with Effexor XR. In addition, at least 7 days should be allowed after stopping

Effexor XR before

starting an MAOI (see CONTRAINDICATIONS and WARNINGS).

 

 

Wyeth Pharmaceuticals Inc. W10404C008

Philadelphia, PA 19101 ET02

Rev 12/03