Holistic Comprehensive Immunotherapy

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Josef M. Issels, MD

Holistic Comprehensive Immunotherapy, The Issels Treatment™

 

http://www.issels.com/treatment.asp?pg=1

 

Josef M. Issels, MD, has become internationally known for his

remarkable rate of complete long-term remissions of " incurable

cancers " in patients who had exhausted all standard treatments, such

as advanced cancers of the breast, uterus, prostate, colon, liver,

lung, brain, sarcomas, lymphomas, and leukemias. After completion of

the Issels Treatment, these patients remained cancer free for up to

45 years, leading normal healthy lives.

 

The Issels Treatment also significantly reduced the incidence of

recurrent cancer after surgery, radiation, and chemotherapy, thereby

considerably improving cure rates.

The Issels Treatment was able to reverse chronic degenerative

diseases such as arthritis, lupus, Grave's disease, Sjoegren's

syndrome, asthma, etc.

 

In 1951 Dr. Issels founded the first hospital in Europe for

comprehensive immunotherapy of cancer. He was the Medical Director

and Director of Research. In 1970 the hospital was enlarged from 80

to 120 patient beds. It contained extensive research facilities

including immunological and microbiological laboratories. The

Hospital's programs included research on tumor vaccines, mycoplasma

and bacterial vaccines inducing fever, hyperthermia, etc. Ninety

percent of the patients treated at the hospital had exhausted

standard cancer treatment.

 

From 1981 until 1987, Dr. Issels served as an expert member of, and

advisor to, the Commission of the German Federal Government in the

Fight Against Cancer.

 

Dr. Issels presented many papers to national and international

medical congresses and within programs of continuing education. He

also published three monographs.

 

Dr. Issels' Concept of the Development of Cancer and Its Treatment

 

The Issels Treatment is based on the concept that malignant tumors

do not develop in a healthy body with intact defense and repair

functions. They present in a specific internal environment which

promotes their growth. This environment develops over a period of

time due to multiple causes and conditions which persist and remain

chronically active even after removal of the tumor (by surgery,

radiation, and/or chemotherapy). These remaining causes are

responsible for the formation of new tumors which occur after local

treatment in every second cancer patient, according to World

statistics.

 

 

click Chart for larger view

Therefore, the Issels Treatment program places equal importance on

the removal of the tumor itself and on the causes and conditions

leading to the body's tendency to develop malignant tumors.

 

The Issels Treatment is based on the following concept:

Pre-and postnatal endogenous and exogenous causal factors (I) can

lead by mutagenic, toxic, sensitizing or neural effects via the

transit mesenchyme to secondary damages to organs and organ systems

and so to functional disturbances of the neural, hormonal, excretory

and defense systems (II).

 

These secondary damages and especially the disturbance of the

detoxification system deteriorate the internal environment , and can

lead to complex metabolic disturbances which are common to all

chronic disease and cancer.

 

Further constant influence of the causal factors and the persistence

of secondary damages can produce a functional imbalance and

deteriorate the defense and repair mechanisms. Depending on

inherited constitution and disposition, this can develop into a

chronic degenerative disease and a " tumor-milieu, " (III) the ideal

medium for cancer cells and micro-organisms found in cancer to

grow. The body has acquired the tendency to produce malignant tumors.

 

With the manifestation of the tumor (IV), the cancer disease enters

the recognizable phase. At this time, conventional cancer treatment

begins with the weapons directed against the cancer tumor and its

symptoms (V).

 

According to the concept that cancer starts as a locally confined

growth, all measures concentrated on the tumor alone seem causal and

exhaustive.

 

Treating the tumor alone is not treating the condition that is

producing it: the underlying cancer disease. Consequently, there is

a high rate of relapse.

 

According to the comprehensive concept, however, cancer is

considered a systemic disease from the onset and the tumor as its

late stage symptom.

 

Following this concept the Issels Treatment has two lines of

approach which are of equal importance and complement each other.

 

A non-specific basic therapy aiming to eliminate causal factors,

repair damages of the early stages, normalize the internal milieu

(terrain), and restore the body's regulative, repair and defense

mechanisms.

 

A specific therapy directed against the malignant tumor itself, such

as surgery, radiation, chemo-, hormone therapy, hyperthermia, and

cancer vaccines.

The non-specific basic therapy corresponds with the etiological path

leading to the immuno-insufficiency and the cancer disease. It is

modified to suit the individual patient's needs. It consists of:

 

Elimination of causal factors, such as head foci of infection

including dental, alveolar and tonsillar foci, malnutrition,

abnormal intestinal flora, fields of neural disturbance, physical

and chemical exogenous factors, endogenous and psychological

factors.

 

Desensitization of the organism which has been sensitized by causal

factors by administration of autohemolysates and colloids.

 

Treatment of secondary damages, metabolic disturbances, the impaired

detoxification and the resulting defense weakness, by general

measures, such as hyperpyrexia or fever therapy, oxygen therapy,

enzyme-therapy, neural-therapy and organ-therapy, as well as

substitution /supplementation according to individual requirements.

The basic therapy is a long-term one without any toxic side effects

and aims at the regeneration of the " big resistance, " which

comprises all the defense zones:

 

The extracorporal zone consisting of the physiological obligatory

microflora which is responsible for the basic immunity of the

organism.

 

The epithelial zone consisting of all epithelial surfaces which

performs defense, filtration, excretion and absorption.

 

The lympho-reticulo defense zone which performs the important tasks

of phagocytosis, antibody production and detoxification. On this

zone, immunotherapy is mainly centered today.

 

The reticulo-histiocytary zone which is the pluripotent mesenchyme

embracing almost half of the body weight. It has been neglected in

cancer research and treatment, altough it is of great importance to

all defense processes due to its various functions:

 

the stemcell function;

 

the transit function that intervenes between all nerves, organ

cells, blood, lymphatic and intestinal cells;

 

the homeostatic function;

 

the defense, detoxification and storage functions.

These defense zones are successive, are closely interrelated and are

under neuro-hormonal control.

 

The blockade of only one function of one of these zones, for

example of the excretion, or even the blockade of the control system

such as the autonomous nervous system may contribute indirectly to a

lowering of the defense potential. During treatment, it was

repeatedly observed that by the elimination of head foci, or with a

fever therapy a blockade of the neuro-hormonal functions was broken.

 

Even in an advanced state of malignant disease an immune reaction

with complete tumor remission can be reached.

 

Holistic comprehensive immunotherapy opens up the following

therapeutic possibilities:

 

Treatment of cancer of all kinds and stages offering a considerable

chance of recovery even for patients in advanced stages who have

exhausted all standard treatments.

 

Follow-up treatment to prevent recurrence after standard cancer

therapy through restoration of the patient's defense and repair

functions (the World rate of recurrence is 50%).

 

Nontoxic preventive treatment for patients at risk, and those with

precancerous diseases.

 

Preparatory treatment prior to surgery, radiation, and chemotherapy

to reduce the risk of complications and in qualified cases, to

render inoperable tumors operable.

 

Treatment of chronic degenerative diseases which are untreatable by

standard methods.