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Tue, 6 Jan 2004 10:49:11 -0500

WC Douglass

Swiss-army drugs

 

Daily Dose

 

January 6, 2004

 

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Pharmaceutical " fishing " for funds and profits...

 

Recently, you've heard me railing a lot about the

pharmaceuticals industry's constant below-the-board cross

marketing of prescription drugs for applications other than

those these drugs were originally approved for. Maybe I'm just

an old fuddy-duddy, but something about the drug company

practice of trying to influence (translation: bribe) doctors

into prescribing a medicine designed for, say, foot fungus to

people suffering from insomnia just rubs my rhubarb the wrong

way.

 

But since a crazy loophole in the law allows MDs to prescribe

ANY approved medication for the treatment of ANY malady under

the sun, this is exactly the kind of thing that's happening all

over the country, and drug companies are raking in the bucks

because of it.

 

However, drug makers are also feverishly attempting to shoehorn

their existing drugs into new, untapped categories of formally

approved usage - some of which stretch the limits of the

imagination. For instance:

 

One drug company with flagging sales (I won't mention any names,

but a lot of its marquis drugs just came " off patent " ) recently

attempted to get a medication designed to help chemotherapy

patients avoid vomiting approved as the first in a whole new

class of antidepressant drug! (Just what we need, huh?) If it

hadn't flunked the trials, they'd likely be able to patent it

all over again and make billions more dollars on it. That's

enough to turn my stomach.

 

Another major pharmaceuticals company may well be on its way to

being able to have one of its tuberculosis drugs approved for

the treatment of phobias! Apparently, a recent study (no doubt

funded by totally independent, unbiased entities) revealed that

the medication helped subjects overcome various irrational fears

with far less therapy than is normally required. But I wonder:

Would it work on those (like you and me) who have a fear of

DRUGS?

 

And how long it will be before the makers of a popular

antidepressant for the elderly will attempt to have their drug

certified as a treatment for arthritis? A recent study (again,

impartially funded, to be sure) shows that patients treated with

the medication reported fewer symptoms of the joint disease.

Even if they can't have the drug officially approved, they'll no

doubt spread the word among doctors.

 

These are just a few more examples of the pharmaceutical

industry " fishing " for new and profitable uses - approved or

otherwise - for medications they've already invested the money

and time into getting approved for one use or another. It's all

just an exercise in shrewd cross marketing.

 

And speaking of drugs and fishing...

 

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For these fish, getting " hooked " has a whole new meaning...

 

Imagine fishing on a nearby lake on a warm, sunny afternoon in

the spring. As you cruise stealthily into a shallow cove in your

flat-bottom boat, you spy them - dozens of fat bluegill sunfish

finning lazily just below the surface. You cast gingerly,

expecting to scatter at least a few of them as bait and bopper

plop lightly onto the water's surface, but none flee.

 

None rush to bite, either. In fact, none even twitch as you

drift in among them. Looking closely, you notice that except for

the subtle flexing of their gills and pectoral fins in liquid

respiration, they seem fearless and serene, almost...

 

Medicated.

 

That's because you're fishing in lovely Lake Lewisville, the

Dallas, Texas-area impoundment a recent Baylor University study

found to be contaminated with, you guessed it: Prozac.

 

More specifically, fluoxetine, the active ingredient in the

antidepressant Prozac. The study showed that the reservoir's

population of common sunfish had absorbed measurable (but not

enough to be therapeutic, sorry fishermen) amounts of

fluoxetine. How'd it get there? According to the study's

authors, most likely through wastewater - specifically through

the urine of those who take Prozac, or from people flushing

those pills down the toilet. (Hey, we can hope, right?)

 

This just goes to show you how little we really know about the

long-term effects of patent medicines - on us and on the Earth

itself. Those poor fish: Hooked, one way or another.

 

Now, I wonder how long it'll be before Prozac's manufacturer,

Eli Lilly and Co., starts cross-marketing it to fishermen as a

can't-miss bait for bluegills.

 

Not taking the mainstream's bait,

 

William Campbell Douglass II, MD

 

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