Fwd: [SSRI-Research] Autism Link to Childhood Vaccinations

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JustSayNo

Sat, 20 Dec 2003 11:18:56 -0500

[sSRI-Research] Autism Link to Childhood Vaccinations

 

For those of you who have been debating the cause of the tremendous rise in

Autism, please read the research found on this professor's

site.

 

It is stated that HUGH FUDENBURG, MD is the world's leading

immunogeneticist and 13th most quoted biologist of our time (nearly 850

papers in peer review journals).

 

Neuro-Therapeutics Research Foundation

http://www.nitrf.org

 

http://www.nitrf.org/fudenberg.html

 

 

 

Added by Frank:

 

http://www.nitrf.org/autistic.html

 

Typical Course of an Autistic patient

 

 

Hepatitis B immunization at 12 hours after birth. DPT immunization at 4 and 8

weeks*; oral polio immunization also at 4 and 8 weeks, again at 3 months.

Schedule now being changed; children will receive 2 doses of live attenuated

oral polio and 2 doses killed polio; oral polio can cause disease; only killed

polio is used in Europe.

 

 

Because of great decrease in cell-mediated immunity (CMI) in infants, the

vaccines lower CMI further; one decreases CMI by 50%; two together by 70%.

Longest safety trial of of the triple vaccine (MMR, all live attenuated viruses)

was three weeks.

 

 

Repeated immunizations with 3 vaccines simultaneously, e.g., pneumococcus,

hemophilus, etc. from 4 weeks to 12 or 18 months. Repeat DPT is given at 12

months.* All these triple vaccines markedly impair CMI.

 

 

Resultant decrease in CMI predisoposes to recurrent viral infections, especially

otitis media, since CMI controls response to viruses (also fungi [e.g.,

Candida], parasites [e.g., leishmaniasis], mycobacteria [e.g., tuberculosis,

even if drug resistant, and leprosy].

 

 

When infections occur, bacterial cultures rarely performed, yet infants

repeatedly given antibiotics. Antibiotics are of asbsolutely no help in viral

infections; in some countries, antibiotic administration without a prior

cultutre is considered malpractice.

 

 

Antibiotics wipe out helpful bacteria in the gut (e.g., lactobacilli,

bifidobacteria) which have important protective functions, including prevention

of infection by yeast, pathogenic bacteria, and/or parasites. The protection is

provided in part by the helpful bacteria clinging to the intestinal cell wall,

thus preventing pathogenic microorganisms from getting to it. The pathogenic

bacteria compete with the body for vitamin B-12 and perhaps other vitamins and

minerals.

 

 

After helpful bacteria wiped out, Candida usually develops. Candida produces

toxin. However its main deleterious effect is avid binding of coenzyme q10,

usually at barely adequate levels in the diet of normals to begin with, to a far

greater extent than by normal tissues. Candida is not the cause of increased

intestinal permeability, except in rare instances, since substances passing into

the body enter via the small intestine (jejeunum) whereas Candida is almost

always confined to the large intestine ( but if present in jejeunum, can be

life-threatening).

 

 

The Candida infection is usually treated with ketoconazole or similar anti-yeast

antibiotic.

 

 

Ketoconazole and similar compounds impair patient's liver function as shown by

liver detoxification profile. This could also be a factor in increased

intestinal permeability, because the liver also synthesizes the J piece (joining

piece) that binds two molecules of IgA antibodies together to form secretory

IgA, which protects the intestinal tract from a variety of damaging agents;

severe diminution of secretory IgA predisposes to increased intestinal

permeability. Furthermore, since the blood vessels from the colon go directly to

the liver via the enterohepatic circulation, the various toxins from

microorganisms and undigested food in the colon go directly to the liver and

impairs the latter's detoxification mechanisms and its production of enzymes.

(The liver produces the vast majority of the hundreds of different body enzymes

necessary for normal metabolism.).

 

 

Decrease in production of the liver enzymes (phosphosulfotransferase and

cytochrome p450 family) causes failure to break food proteins (including gluten

and casein) into peptides. The intact proteins cross into circulation, and

antibodies** are formed against them. The antibodies complex with the antigen to

form antigen-antibody complexes, that in turn can enter various organs and seek

out cells with receptors for antigen-antibody complexes, e.g., cells of the

joints (causing arthritis), muscles (causing myalgia), or brain (causing

cognitive dysfunction).

 

 

*DPT immunization in inbred mice has been shown to result in decrease synthesis

of cytochrome p450 and of phosphosulfotransferase and of the messenger RNA's

necessary for their production.

 

**If antibodies are not detectable, this may be due to immune complex in antigen

access.

Prevention

 

 

The law states that infants with immune defects should not receive

immunizations. But no pediatricians test for immune deficiency before giving

immunizations. They are always given out of convenience for pediatricians at

well-baby follow-ups at 4 and 8 weeks in this country.

 

 

Defer Rubella vaccine in males completely, in females defer until age when

menses begins. Rubella is only a mild disease in the developed countries, with

mild fever and " spots " for three days. Reason for females taking it a menses is

because if Rubella occurs in the first trimester of pregnancy the child will

develop severe congenital defects starts to prevent congenital defects. If

administered during first or second trimester do not give to women for at least

2½ years following delivery of last child, as the vaccine virus is present in

respiratory secretions for seven days and can cause disease.

 

 

Defer other immunizations until age 4 (except for tetanus and diphtheria toxoid

which should be given at 2½ years).

 

 

Obtain IgG antibody titers from cord blood to all vaccines currently in use and

store away a sample of serum so they can be tested for vaccines which will be

introduced later (we are introducing 1-2 new immunizations each year). If any of

the IgG antibody to DPT, MMR, polio (and in the British Commonwealth countries

16 Coxsackie viruses), get IgM on infant from the stored serum (divided into 2

parts), and the mother, father and the sib of closest age should be tested for

IgG and IgM antibodies to the relevant virus.

 

 

Do not take influenza vaccines or other new vaccines. Ask the physician if the

vaccine bottle contains mercury (thiomerol or alum [which boosts the response to

various immunizing agents]). Also ask physician to obtain vaccines free of

these. Repeat injections of these agents can cause all kinds of immunologic

aberrations.

 

 

Nurses in newborn nurseries should not receive rubella vaccine. Rubella

immunization of nurses in Philadelphia 12 years ago, because of several cases of

rubella in newborn infants, resulted in a micro-epidemic of CFIDS.

 

Treatment of Autistic Spectrum Disorders

 

A. Non Specific Therapies (i.e. not limited to one disorder within the spectrum)

 

 

For Candida infections give Diflucan, asynthesized antifungal, but only if

Candida is demonstrated in stool, urine, finger- and toe-nails, and/or vagina,

etc., or if serum Candida detection test gives highly positive results. If

present in stool, patient's own Candida should be tested against specific

antifungals and six natural substances to see which of these the organism is

mosr subseptible. Lactobacillus acidophilus and thermophilic bacteria to

eradicate and put good bacteria back in the bowel. If refractory, use

Candida-specific transfer factor.

 

 

If serious reaction to the immunization, measure antigen-antibody complexes by

four methods. If elevated: (a) plasmapheresis or (b) Theoretical: a method that

has been used for Digitalis toxicity: Couple antibody to offending toxin or

vaccine virus to Sephadex Columns and pass plasma through this to remove

anti-toxin or vaccine and return plasma to patient (if this is difficult to

understand, it does not differ that much from dialysis for kidney failure.)

 

 

At age 15 months, get IgG titers to measles, mumps, rubella, HHV-6, DPT (all 3),

cytomegalovirus, antibody to the " early " antigen EBV, also mycoplasma fermentens

and chlamydia. (TF's available for most of these).

 

 

Often increased intestinal permeability; if present, correct by appropriate

dietary means (can be determined by very simple test). For most severe increased

intestinal permitability, restrict diet to rice-based milk-free, wheat-free,

corn-free, and sugar-free diet containing amino acids and proteins (astronauts'

diet) for three months.

 

 

Comprehensive Stool Analysis (e.g., Great Smokies Diagnostic Laboratories-GSDL)

for pathogenic bacteria, yeast, and parasites. If present, test sensitivity to

natural agents and antibiotics; use those agents to which patient's pathogens

are most sensitive. If chymotrypsin is subnormal in the stool, add oral enzymes,

preferably alphazyme or gammazyme. If stool pH is alkaline and patient complains

of upper abdominal distress, add betaine (tri-methylglycine). Take sublingual

vitamins and zinc.

 

 

If elevated toxic metals or deficient trace minerals on screening by hair

analysis, repeat abnormal levels by blood test. Also measure content of metals

and minerals in drinking water.

 

 

Test for malabsorption, especially if stools float or are intermittently light

colored. If so, oral vitamins and minerals are only partially absorbed;

administer such sublingually.

 

 

 

 

 

 

 

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