Guest guest Posted December 4, 2003 Report Share Posted December 4, 2003 SSRI-Research , JustSayNo Thu, 04 Dec 2003 08:29:43 -0500 [sSRI-Research] SSRI Withdrawal Syndrome SSRI Withdrawal Syndrome ------ http://www.psycom.net/depression.central.withdrawal.html The following criteria define the SSRI (or venlafaxine) withdrawal syndrome: Criterion A: A course of treatment in which an SSRI (or vanlafaxine) is stopped or interrupted or the dose is reduced after a period of 4 weeks or more. Criterion B: Two or more of the following symptoms develop within 1 to 10 days of criterion A (except for fluoxetine in which case the symptoms must develop within 28 days): (a) dizziness or light headedness (b) nausea and/or vomiting © headaches (d) lethargy (e) anxiety and/or agitation (f) tingling (parasthesias), numbness or " electric " shock-like sensations (g) tremors (h) sweating (i)insomnia (j) irritability (k) vertigo (dizziness) (l) diarrhea Criterion C: The symptoms of criterion B cause clinically significant distress or impairment in social, occupational, or other important areas of functioning. Criterion D: The symptoms are not due to a general medical condition or the direct physiological effects of another substance (e.g., a medication or a drug of misuse) that has been recently commenced, stopped, or altered in dosage. Criterion E: The disorder is not better accounted for by an exacerbation/ relapse/recurrence of the psychiatric disorder for which the SSRI was prescribed. Adapted from: Haddad PM The SSRI discontinuation syndrome: literature review and provisional diagnostic criteria. Presented at: XXIst Collegium Internationale Neuro-Psychopharmacologicum Congress. July 12-16, 1998; Glasgow, Scotland. Reprinted in International Drug Therapy Newsletter. 1998, 33, 46. Quote Link to comment Share on other sites More sharing options...
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