Guest guest Posted September 25, 2009 Report Share Posted September 25, 2009 Long-term persistence of vaccine-derived aluminum hydroxide is associated with chromnic cognitive dysfunction Long-term persistence of vaccine-derived aluminum hydroxide is associated with chronic cognitive dysfunctionIn Press, Corrected Proof, Available online 20 August 2009Journal of Inorganic Biochemistry Maryline Couette et al.Macrophagic myofasciitis (MMF) is an emerging condition, characterized by specific muscle lesions assessing long-term persistence of aluminum hydroxide within macrophages at the site of previous immunization. Affected patients mainly complain of arthromyalgias, chronic fatigue, and cognitive difficulties. We designed a comprehensive battery of neuropsychological tests to prospectively delineate MMF-associated cognitive dysfunction (MACD). Compared to control patients with arthritis and chronic pain, MMF patients had pronounced and specific cognitive impairment. MACD mainly affected (i) both visual and verbal memory; (ii) executive functions, including attention, working memory, and planning; and (iii) left ear extinction at dichotic listening test. Cognitive deficits did not correlate with pain, fatigue, depression, or disease duration. Pathophysiological mechanisms underlying MACD remain to be determined. In conclusion, long-term persistence of vaccine-derived aluminum hydroxide within the body assessed by MMF is associated with cognitive dysfunction, not solely due to chronic pain, fatigue and depression. www.iamnolabrat.com Keep up with people you care about with India Mail. Learn how. Quote Link to comment Share on other sites More sharing options...
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