Jump to content
IndiaDivine.org

Neuroleptic Malignant Syndrome (NMS)

Rate this topic


Guest guest

Recommended Posts

Guest guest

Dear

Master Fe

NAMASTE

could you please let me know the protocol for healing

NEUROLEPTIC MALIGNANT SYNDROME?

The patient is a 71 year old male admitted to the hospital. He was

on these drugs from past 40 yrs.

LITHIUM,RELEXON,TRIBIUM & ATVIN. These drugs have created a lot of

toxins in his blood and urine.

He is in a semi unconsious state,heart,pluse normal. please guide

me for the ph treatment.

WITH DEEP GRATITUDE,

WITH GREETINGS OF LOVE AND LIGHT,

i remain,

chhaya

negandhi-------------------

 

Dear Chaya,

 

Greetings.

 

MEDICAL INFORMATION: NEUROLEPTIC

MALIGNANT SYNDROME (NMS)

 

" Neuroleptic malignant syndrome or NMS is a drug-induced disorder,

characterized by disturbances in mental status, temperature regulation,

and autonomic and extrapyramidal functions. It is a rare, but potentially

life-threatening disorder associated with the use of antipsychotic

medications and other medications with similar pharmacologic properties.

Although NMS is rare, its potential for morbidity and mortality, as well

as the wide-spread use of antipsychotic drugs, suggests that the absolute

number of cases is significant. Because of its infrequent occurrence,

individual practitioners may have limited experience in diagnosing and

managing NMS cases. Also, systematic and standardized research has been

hampered by the difficulties in collecting a sufficient number of cases,

resulting in a lack of consensus on a number of issues.

 

NMS was first described in France during early clinical trials of

antipsychotics. Despite studies confirming its occurrence, NMS remained

obscure and unrecognized until the 1980s. Since that time, numerous

clinical reports and reviews have provided valuable information

facilitating the development of standardized criteria and treatment

strategies. The defining features of NMS may develop dramatically

within hours or insidiously over several days. NMS is diagnosed by the

development of muscle rigidity and elevated temperature following the

administration of antipsychotic medication. Additional features include

changes in mental status (obtundation, catatonia), vital signs

(tachycardia, unstable blood pressure), and extrapyramidal function

(tremors, dysarthria, dysphagia, drooling). Associated laboratory

findings include leukocytosis, elevated creatine phosphokinase, and

metabolic acidosis.

 

The neuroleptic malignant syndrome (NMS) is a rare, but life-threatening,

idiosyncratic reaction to a neuroleptic medication. The syndrome is

characterized by fever, muscular rigidity, altered mental status, and

autonomic dysfunction. Although potent neuroleptics (e.g., haloperidol,

fluphenazine)are more frequently associated with NMS, all antipsychotic

agents, typical or atypical, may precipitate the syndrome [eg,

prochlorperazine (Compazine), promethazine (Phenergan), clozapine

(Clozaril), risperidone (Risperdal). NMS has also been associated with

non-neuroleptic agents that block central dopamine pathways

[e.g.,metoclopramide (Reglan), amoxapine (Ascendin), lithium].

 

CAUSES:

1. All classes of neuroleptics (dopamine D 2-receptor antagonists) are

associated with NMS, and dopamine receptor blockade is considered the

cause of NMS.

2. Experimental blockade of dopamine in the striatum can cause rigidity,

tremor, and rhabdomyolysis.

3. Blockade of dopamine in the hypothalamus can cause impaired

temperature regulation and hyperthermia.

 

Risk factors for developing NMS include: increased ambient temperature,

dehydration, patient agitation or catatonia, rapid initiation or dose

escalation of neuroleptic, withdrawal of anti-Parkinson medication, use

of high-potency agents and depot intramuscular preparations, history of

organic brain syndrome or affective disorder, history of NMS, or the

concomitant use of predisposing drugs (e.g., lithium, anticholinergic

agents).

 

LAB STUDIES:

Complete blood count (CBC), Blood cultures, Liver function tests (LFTs),

Blood urea nitrogen (BUN) and creatinine, Calcium and phosphate

levels, CPK, Urine myoglobin, Arterial blood gas (ABG), PT, PTT,

INR, Serum and urine toxic screening (e.g., salicylates, cocaine,

amphetamines) Imaging Studies, A chest x-ray (CXR) if

aspiration pneumonia is a concern, A head CT scan to rule out a

structural lesion or before a lumbar puncture (LP).

There is no universal agreement on the absolute need for a CT scan prior

to the LP in patients without clinical evidence of a structural lesion.

The decision is left to the individual practitioner.

 

EMERGENCY DEPARTMENT CARE: Successful treatment requires prompt

recognition, withdrawal of neuroleptic agent, exclusion of other medical

conditions, aggressive supportive care, and administration of certain

pharmacotherapies.

 

1. A careful history should be taken before starting a new neuroleptic

medication.

2. NMS may recur when medications are restarted.

3. Monitor a patient carefully while administering neuroleptic medication

to prevent excessive agitation and dehydration, since these conditions

may predispose a patient to NMS.

4. Physical restraints may be useful.

5. Stop all neuroleptics.

6. Correct volume depletion and hypotension with IV fluids.

7. Methods to reduce the temperature include: cooling blankets,

antipyretics, cooled IV fluids, ice packs, evaporative cooling, and

various pharmacotherapies to reduce rigidity (see below).

8. When rhabdomyolysis occurs, maintain vigorous hydration and alkalinize

the urine to prevent renal failure.

9. Electroconvulsive therapy (ECT) has been used to treat NMS. Anecdotal

success reported.

10. It may be useful in treating an underlying psychiatric disease in

those patients unable to take neuroleptics.

11. The patient must be monitored closely to rule out underlying

infection.

12. The patient’s psychiatric disease must be evaluated and treated

during withdrawal of neuroleptic medication.

 

Further Outpatient Care:

NMS may be prolonged. If the patient is discharged, close follow-up care

should be given to monitor residual symptoms. If neuroleptics are to be

reinstituted, they should be administered at relatively low initial

doses.

 

Transfer:

If NMS is diagnosed in a psychiatric facility, the patient should be

transferred to an acute care medical facility where intensive monitoring

and treatment is available.

 

Deterrence/Prevention:

Take a careful history before starting a new neuroleptic medication. NMS

frequently recurs when medications are restarted. Monitor a patient

carefully while administering neuroleptic medication to prevent excessive

agitation and dehydration, since these conditions may predispose a

patient to NMS.

Physical restraints may be useful.

 

COMPLICATIONS:

Rhabdomyolysis, renal failure, seizures, respiratory failure, aspiration

pneumonia, decompensation of psychiatric disease with the withdrawal of

neuroleptics.

 

Patient Education:

After an episode of NMS, the patient must be told that he/she is at risk

for recurrence if rechallenged with a neuroleptic medication. "

 

 

 

PRANIC HEALING TREATMENT:

 

1. General sweeping with LWG several times.

2. Sweep the front and back solar plexus and the liver.

Thorough cleansing is important. Energize the front solar plexus

with LWG, LWB, then with LWO. Do not appy LWO if patient is

suffering from loose bowel movement or intestinal bleeding. Apply

more sweeping. Sweep the liver, stomach, small and large

intestines.

3. Sweep the front and back heart chakra. Energize the back heart

with LWG, LWV, then with slightly with EV.

4. Sweep the left and right lungs. Energize the back heart

DIRECTLY through the back of the lungs with LWB, LWG, then with

LWO. Wait for 1 to 2 minutes. Energize with LWR.

5. Sweep the entire spine with LWG.

6. Sweep front and back spleen. Energize slightly with

WHITE. Apply more sweeping.

7. Sweep the basic and navel chakras. Energize with

WHITE. No energizing of basic chakra if patient has fever.

8. Sweep the hand and sole chakras. Energize them with LWV.

(Do this step maximum of ONCE a day.)

9. Sweep alternately with LWG & LWV the entire head and

the left and right brain. Sweep the crown, forehead, ajna, back

head minor, jaw minor, throat, and secondary throat minor chakras with

LWG & LWV. Energize the chakras with LWG, then with more of

LWV.

10. Repeat treatment 2 to 3 times a week.

11. Stabilize and release.

12. Alternate advanced pranic healing treatment with pranic

psychotherapy. At least about 2 times a week. Give emphasis

on sealing cracks and holes and disintegrating negative elementals and

thought entities.

 

Love and light, masterfe

Link to comment
Share on other sites

Join the conversation

You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
×
×
  • Create New...