MPS

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greetings to master fe & all on the list,

 

we have a patient (19 months old baby boy) who has been diagnosed as

having MPS.

 

have been doing cleansing with emphasize on the eliminative organs -

liver, lungs, pancreas,spleen, kidneys and also the endocrine glands.

 

would appreciate very much if we can have some feedback on how to

effectively treat this condition.

 

with much gratitude,

tek ming

 

 

btw, here is some brief description obtained from the website of one

of the support group for MPS

 

An MPS baby appears normal at birth and seems to develop normally for

about the first year or more depending on which MPS type the child is

affected with. The first signs can vary and are evident at different

ages in affected children. Symptoms that usually prompt medical

attention are ear infections, runny noses and colds.

The mucopolysaccharide storage disorders are progressive and vary

widely in severity. All MPS children tend to have coarse facial

features. All of them have, in some degree, skeletal involvement. In

most children this involves joint changes with limitation of

movement. In all of the MPS disorders, multiple organs are involved.

Several children have clouding of the cornea which leads to vision

impairment. Enlargement of the liver and spleen and involvement of

the heart and blood vessels are frequent symptoms.

 

Progressive mental retardation is present in some children, as well

as umbilical and groin hernias, stunted growth, fluid on the brain,

thickened skin, excessive hair growth, chronic runny nose, chronic

ear infections causing hearing loss, and a projected life expectancy

of ten to twenty years.

 

 

Mucolipidoses

In the Mucolipidoses (ML) class, all of the mucopolysaccharide

enzymes are present, but in most cases the enzymes continually leak

out of the cell. As a result, the mucopolysaccharides are not

completely broken down. The lysosomal enzymes in the ML disorders

lack a phosphate group which is necessary for directing the enzymes

into the lysosomes. Therefore, the mucopolysaccharide and lipid

materials accumulate in the cells and tissues.

 

The ML disorders have symptoms including coarse facial features,

stiff joints, stunted growth, heart murmurs and mental retardation

ranging from mild to severe. Some of those affected with ML

experience clouding of the cornea, enlarged liver and spleen, and ear

infections. These diseases, like MPS, are progressive.