Sodium Thiosulfate .... fish prosper and so do humans.

[Guest guest]

Thank you Nancy for your very interesting and informative post - I

have now saved it as a reference in my archives.

 

 

oleander soup , " N. English " <englishvinal

wrote:

>

> Just came in from my doctor friend in Brazil.

>

> I provided him with the basic research and he has

> written this article. Very benficial.

>

> We need to know this kind of information that our " we

> are from the govt. and we are here to help you " folks

> are keeping from us.

>

> Nancy E.V.

>

> ...........................................

> Sodium Thiosulfate - March

> 29, 2007

>

> Sodium Thiosulfate International Medical Veritas

> Association

>

> Sodium thiosulfate is used to remove heavy metals

> from polluted streams. It maintains a dual role as a

> potent antioxidant and chelator of calcium and other

> toxic substances.

>

> Sodium thiosulfate is an exciting natural medical

> substance useful in a surprisingly broad range of

> clinical situations.

>

> Though normally used intravenously, orally and

> transdermally it can and should be used for treating

> tap, distilled and reverse osmosis water for water

> detoxification, mineralization and other extended

> health benefits.

>

> It is extremely inexpensive, safe to use and widely

> available. The EPA states, " Sodium thiosulfate has

> been safely used for over 100 years as a

> therapeutic agent; medical uses of sodium thiosulfate

> have been well documented since 1895. " Sodium

> thiosulfate is classified by the FDA as a

> Direct Food Substance Affirmed as Generally Recognized

> as Safe.

>

> Sodium thiosulfate is a natural substance found in

> hot,water springs. It is one of the secret

> ingredients, which gives these springs their healing

> power.

>

> Intravenous sodium thiosulfate is currently used as an

> antidote for the treatment of cyanide poisoning and

> prevention of toxicities of cisplatin cancer

> therapies. It is used as a food and medicinal

> preservative and topically used as an antifungal

> medication. The sulfur smell component of the hot

> mineral springs is sodium thiosulfate.

>

> Thiosulfate is unique; it reacts with free radicals

> (oxygen) to form a sodium sulfate compound which

> prevents the radicals from destroying or attacking

> the cells. This is perhaps why the elderly like to

> visit hot mineral springs.

>

> Sodium thiosulfate may be effective in reducing some

> chemically induced cancers.

>

> Pet shops all know and sell sodium thiosulfate as a

> de-chlorinator used in fish tanks to remove the

> chlorine (and other halogen compounds) so the

> toxicity of these chemicals do not kill the fish. One

> can buy it in 1 kilo bags from a chemical supply

> store.

>

> We need very little of it and it is mixed 10% sodium

> thiosulfate added with 90% water.

>

> It can be used in our own drinking water to rid it of

> cancer causing components. We need to be sure to

> eliminate the chlorine from the water we drink and

> bathe in. Chlorine in bath water is inhaled and

> absorbed, especially from hot water.

>

> This is important as chlorine is a deadly poison. It

> can produce fatigue and tiredness after the bath.

> Industrial chemist, J.P. Bercz, Ph.D., showed in 1992

> that chlorinated water alters and destroys

> unsaturated essential fatty acids (EFAs), the building

> blocks of people's brains and central nervous systems.

>

>

> The compound hypochlorite, created when chlorine mixes

> with water, generates excess free radicals; these

> oxidize EFAs, turning them rancid. Both chlorine and

> fluoride inhibit the stomach's ability to produce HCl,

> and impair the ability of

> beneficial flora to grow in the gut.

>

> While taking a warm shower or lounging in a hot tub

> filled with chlorinated water one inhales chloroform.

> Even worse, warm water opens the pores, causing the

> skin to act like a sponge. One will absorb and inhale

> more chlorine in a 10-minute shower than by drinking

> eight glasses of the same water.

>

> A window from the shower room open to the outdoors

> removes chloroform from the shower room air, but to

> prevent absorption of chlorine through the skin, a

> shower-head that removes chlorine from shower water is

> a must. In the bath water the solution of course

> is sodium thiosulfate. Swimming pools, often with high

> chlorine concentrations are also a danger, especially

> for children who already have damaged or deficient

> sulfate pathways.[ii]

>

> Sodium thiosulfate (STS) is a calcium chelating agent

> with antioxidant properties.

>

> Dr. Carlos E. Araya

>

> Figure 1. (A) Initial three-phase bone scan

> demonstrating soft tissue accumulation in thighs,

> distal femur, proximal tibia, and forearms. There is

> intense uptake in the myocardium and early

> accumulation in the lungs. (B) Three months

> later, the calcium deposition in the thighs and

> forearms is less significant. However, there still is

> calcification in the heart, lungs, and

> para-articular surfaces.

>

> The beneficial effects of sodium thiosulfate (STS) are

> thought to be due in part to its ability to enhance

> the solubility of calcium deposits. STS has a small

> molecular weight of 248 (Na2S2O3) and in

> patients with normal renal function has a serum

> half-life of 15 min. STS facilitates the mobilization

> of calcium from vessels affected by calcium deposits.

>

> Intravenous STS seems beneficial, has mild adverse

> effects, and is well tolerated in children and young

> adults.

> STS dosage was 25 g/1.73 m2 per dose intravenously.

>

>

> Dr. Carlos E. Araya

>

> Dr. Carlos E. Araya et al[iii] successfully used this

> relatively nontoxic substance, which been reported as

> adjuvant treatment of several conditions involving

> disorders of calcium homeostasis. Yatzidis described

> its benefits by decreasing the rate of new kidney

> stone development in 34 patients with recurrent

> calcium urolithiasis.

>

> Prompted by these excellent results, intravenous STS

> was administered after hemodialysis to three patients

> with ESRD and tumoral calcinosis for a period of 6 to

> 12 mo. Two of the patients had regression of the

> calcified mass as well as improved motility of the

> affected joints.

>

> STS was given for a period of 9 yr to a patient with

> nephrocalcinosis as a result of renal tubular acidosis

> type 1. There was no further deterioration of his

> condition, and the discontinuation of the medication

> was accompanied by recurrence of renal colic.

>

> Sodium thiosulfate may be tried to treat arsenic

> poisoning. When used in combination with sodium

> molybdate sodium thiosulfate may be useful for the

> treatment of copper poisoning.[iv]

> Presumably the sulfate moiety may react with and

> chelate this and other heavy metals, allowing their

> removal. It is also used to clean up environmental

> mercury spills.[v]

>

> Sodium thiosulfate is not only non-toxic it is life

> giving. Just add a couple of drops of sodium

> thiosulfate and fulvic to plants and they will grow

> and bloom quickly and beautifully though one will

> observe that fulvic acid alone doesn't work well

> without the presence of sodium thiosulfate.[vi]

> Interestingly this material from hot spring

> waters acts like sea water in that both can have

> dramatic life giving effects.

>

> Traditional scientific thinking would have us believe

> that after the tsunami-affected land in Indonesia's

> Aceh province was flooded crops grown from the land

> would be devastated by the salt water. But many

> farmers shook off the shock of the catastrophe and

> planted seeds and grew new crops. What farmers found

> out was that the soil grew crops stronger and heavier

> than anyone had seen in half a century of farming

> there.

> One positive from the disaster was the discovery that

> sea water holds the secret to soil fertility. What we

> need to understand is that it is the minerals in the

> ocean that are the ultimate seasoning for soil, for

> plants, animals and humans alike.[vii]

> (Magnesium Oil thus is a great fertilizer for it is

> condensed sea water with almost all the salt removed.)

>

> The sea water turned out to be a great fertilizer.

> We are looking at yields twice as high as last year.

>

> Muhammad Yacob

>

> Sodium thiosulfate (SOE-dee-um thye-oh-SUL-fate) may

> be used to lessen some of the side effects of

> cisplatin (a cancer medicine). Reporting in the July

> issue of the Journal of Pharmacology and

> Experimental Therapeutics, researchers with the

> Portland U.S. Department of Veterans Affairs Medical

> Center and Oregon Health Sciences University have

> found that they can prevent or sharply reduce hearing

> loss with sodium thiosulfate.

>

> Dr. Ed Neuwelt reported, " When we used the drugs such

> as sodium thiosulfate, it binds the platinum and

> prevents the platinum from injuring the outer hair

> cells. " Sodium thiosulfate is the first medicinal

> substance shown to prevent chemotherapy-induced

> hearing loss.

>

> This is important for approximately a third to

> one-half of cancer patients treated with the

> platinum-based chemotherapy agent cisplatin develop

> some

> degree of communication difficulty due to hearing

> loss.

> Sodium thiosulfate does not affect the endocrine

> system, except as a detoxifying agent of compounds

> that have been shown to adversely affect the endocrine

> system (i.e. chlorine and other reactant

> species).

>

> US EPA

>

> It is also used with another medicine in the

> emergency treatment of cyanide poisoning.[viii] Sodium

> thiosulfate is a water soluble salt and reducing agent

> that reacts with oxidizing agents. Although its exact

> mechanism of action is unknown, thiosulfate likely

> provides an exogenous source of sulfur, thereby

> hastening the detoxification of

> cyanide through the enzyme rhodanese (thiosulfate

> cyanide sulfurtransferase) which converts cyanide to

> the relatively nontoxic, excretable thiocyanate ion.

> In addition, this agent neutralizes the reactive

> alkylating species of nitrogen mustard, thereby

> decreasing skin toxicity related to nitrogen mustard

> extravasation.

>

> Though it is not recognized in research sodium

> thiosulfate may also be helpful with our joints and

> rheumatism which also come under free radical attack.

> This is not imagination since people with arthritis

> and rheumatism do go for treatment in many high sulfur

> (rich in sodium thiosulfate) springs for their cure.

> This is why MSM is also effective against arthritis as

> well, due to the sulfur content.

>

> 92% of autistic children seem to be wasting sulfate

> in the urine; for blood plasma levels are typically

> low and urinary levels are high. There is also an

> abnormal cysteine to sulfate ratio.[ix]

>

> Dr. Rosemary Waring

>

> Sulfate is the most oxidized form of sulfur. It

> doesn't need to be oxidized any more, so supplementing

> or bathing in sulfate supplies what is lacking because

> of the body's inability to oxidize the sulfur in

> foods. This is especially important for autistic

> children.[x]

>

> Most children on the autism spectrum are very low in

> sulfate and may be as low as 15 percent of the amount

> in neurologically typical people.

>

> People with low or no ability to convert compounds to

> sulfate have problems handling environmental

> chemicals, some medications, and even some chemicals

> produced within the body.

>

> They include people with other conditions such as

> Alzheimer's disease, Parkinson's disease, rheumatoid

> arthritis, and chemical sensitivities.[xi]

>

> PST (phenol-sulfotransferase) is a Phase II[xii]

> enzyme that detoxifies leftover hormones and a wide

> variety of toxic molecules, such as phenols and amines

> that are produced in the body (and even in the gut by

> bacteria, yeast, and other fungi) as well as food dyes

> and chemicals.

>

> These reactions include the breakdown of bilirubin and

> biliverdin, which are the breakdown products of

> hemoglobin. There are many varieties of phenols. This

> may indicate why children's intolerances vary. Sulfate

> must be grabbed by any sulfotransferase before the

> enzyme can attach it to something else.

>

> If the PST enzyme activity is low, you can boost it

> by increasing the amount of sulfate available to it.

>

> The PST enzyme links an oxidized sulfur molecule (a

> sulfate) to these various toxic substances to

> solubilize them so the kidneys can

> dispose of them. Obviously, if sulfate is low or

> missing, this can't happen effectively.

>

> Dr. Rosemary Waring's research shows that the lack of

> sulfate is the primary problem in most autistic

> children. Cysteine is the amino acid that should be

> used to make sulfate, so it appears that the sulfate

> is probably being utilized far faster than the

> cysteine can be converted, leaving a deficit of

> sulfate (sugar wastes it), or the cysteine is not

> being metabolized to sulfate. [xiii]

>

> Similar sulfate deficiencies have been reported in

> people with migraine, rheumatoid arthritis, jaundice,

> and other allergic conditions all of which are

> anecdotally reported as common in the families of

> people with autism.

>

> People with the PST/low sulfation problem have

> central nervous system problems from the toxic

> amines.[xiv]

>

> Dr. Rosemary Waring

>

> Sulfate has a negative charge, and performs all sorts

> of unique biological functions. As with Epsom salts

> (magnesium and sulfate) the two elements sodium and

> sulfate dissociate in solution. The sulfate

> is absorbed into the body through the skin when one

> takes a bath with it. Because the sulfur is already in

> the sulfate form, it does not need to be converted

> like other forms of sulfur do.

>

> Sulfate is thought to circulate in the body up to

> about nine hours. Any sulfate left on the

> skin may continue to be absorbed as long as it is

> still on the skin, offering continuous

> 'timed-released' input into the bloodstream - like

> medications given through skin patches. Many mothers

> use Epsom salt baths for their autistic children but

> the magnesium is not as well absorbed for some reason

> as it is with magnesium chloride. It is recommended

> that magnesium chloride be used instead, and that

> sodium thiosulfate be mixed in to supply the sulfate

> so the kids get the best of both worlds.

>

> The paradigm of autism is shifting from what was once

> believed to be a heritable, incurable mental illness,

> to an environmentally- triggered, and most

> importantly, treatable medical disorder.[xv]

>

> National Autism Association

>

> Sodium thiosulphate results in the formation of

> calcium thiosulphate in the urine, a compound with

> much higher solubility than the other calcium salts

> (phosphate, oxalate). Thus, sodium thiosulphate

> could not only inhibit further nephrocalcinosis, but

> in some degree it could contribute to decalcification

> of renal parenchyma[xvi].

>

> In addition, sodium thiosulphate could attenuate

> toxicities from chemicals and metabolites due to its

> ability to stabilize glutathione (GSH) levels in

> various tissues, including brain, liver and kidney.

>

> GSH plays an important role in host defense, since

> it limits the action of oxygen free radicals and

> protects cells from oxidative stress. In this regard,

> sodium thiosulphate injection 1 h before, or 30 min

> after, cisplatin infusion attenuated renal injury in

> experimental animals.

>

> Similarly sodium thiosulphate-associated protection

> has been found after exposure to paraquat,

> hypochlorous acid and other drugs and chemicals.[xvii]

> In conclusion, oral supplementation of sodium

> thiosulphate in addition to alkali and potassium in

> the case of RTA-I seems to offer protection against

> progression to nephrocalcinosis and to renal

> failure.[xviii]

>

> Sodium thiosulfate's topical antifungal activity is

> probably due to its slow release of colloidal sulfur.

>

> There are those who suspect that sodium thiosulfate

> will neutralize the toxicity of vaccine poisons such

> as ethyl mercury.[xix]

>

> Sodium thiosulfates will convert chlorine

> hypochlorites into safe sodium sulfate and sodium

> chloride as a by product. When a little is applied to

> our drinking water it is excellent in converting toxic

> substances into harmless chemicals that can be easily

> excreted by the urine. It protects the fish and it

> will protect us.

>

> Sodium thiosulfate may help with the absorption of

> vitamins and minerals.

>

> Sodium thiosulfate is emerging as a treatment for

> calciphylaxis.[xx] It is capable of donating its two

> unpaired electrons, is a scavenger of reactive oxygen

> - nitrogen species, and may generate glutathione.

>

> Additionally, it is an excellent chelator of calcium,

> which is a problem in diabetes resulting in medial

> vascular ossification - calcification.

>

> The peripheral arteriolopathy associated with diabetes

> and skin ulcerations are all too frequently

> recalcitrant to standard therapy and result in untold

> complications with eventual limb loss.

>

> It is entirely possible that therapy with sodium

> thiosulfate could promote healing of these ulcers and

> prevent limb loss by accelerating healing of these

> peripheral diabetic ulcers just as it has been so

> helpful in the recent months in promoting healing of

> the skin ulcerations associated with

> calciphylaxis.[xxi]

>

> Sodium thiosulfate can be applied to free radical

> formations in heart disease and free radical formation

> in our blood vessels.

>

> In a case of a man on dialysis for 30 years, no

> history of diabetes, non smoker who developed

> peripheral arterial disease rendering him unable to

> walk; with severe pain - ulcers on toes and fingers,

> with toes developing into gangrene despite intensive

> treatment including hyperbaric oxygen, doctors turned

> to sodium thiosulfate.

>

> Pain became so bad he was unable to sleep in supine

> position. Intravenous sodium thiosulfate (20 g) was

> used 3 times weekly. Within 4 - 5 days, the patient

> experienced rapid and dramatic pain relief. The score

> of the visual analogue pain scale improved from 10/10

> - 2/10. The signs of ischemia, measured by

> transcutaneous partial oxygen pressure and

> thermography, improved significantly. During the

> infusion of sodium thiosulfate, the patient complained

> of nausea, vomiting and hyperosmia. These adverse

> symptoms were resolved after discontinuation of the

> infusion.

>

> Pain relief was sustained and he could walk after 2

> weeks of infusion. Our case supports the use of sodium

> thiosulfate as a novel therapeutic choice for critical

> limb ischemia with severe vascular calcification in

> chronic

> Hemodialysis patients.[xxii]

>

> In vitro studies with sodium thiosulfate and LX-1

> small-cell lung carcinoma cells found that sodium

> thiosulfate concentrations of 10 mg/kg and above were

> toxic to LX-1 cells, presumably due to high

> osmolarity.

>

> US EPA

>

> Cicone et al. were the first to report the benefits

> of STS in one peritoneal dialysis patient with

> calcific uremic arteriolopathy (CUA), which is a rare

> complication of end-stage renal disease in which

> thrombosis occurs in calcified arteries, leading to

> infarction and infection of the affected tissues.

>

> They noted significant pain relief as well as

> reduction in the size and the induration of the

> subcutaneous plaques after a total of 8 months of

> treatment.

>

> In two patients with severe ulcerative lesions, the

> use of STS was associated with reduction in pain,

> reduced inflammation, and improved healing. One of the

> patients received concomitant therapy with a

> Continuous Veno Veno Hemodialysis (CVVH) machine in an

> attempt to maintain a constant state of mild

> hypocalcemia and optimize removal. The only noted

> adverse effects during the treatment period in two of

> the patients were mild nausea and vomiting and

> metabolic acidosis.

>

> Because of the rapid progression of symptoms, we

> opted to use CVVH and STS in one of our patients. The

> other two patients received STS after each

> hemodialysis session. In our experience as well as

> that of others, the most dramatic change was that of

> pain relief. This relief was noted in all patients

> within the first days after initiation of treatment.

> The mechanism for pain relief has been hypothesized to

> be due to the antioxidant properties of STS, which by

> restoring endothelial function can enhance endothelial

> nitric oxide production, promoting vasodilation and

> reducing pain.

>

> In our patients, the subcutaneous plaques, although

> still present, were reduced in size and became softer

> and less tender within weeks. Radiologic evidence of

> decreased calcification also was noted. However, only

> one of the patients had significant functional

> improvement in the mobility of the affected areas.

>

> A chemist in Thailand reported that injections of

> sodium thiosulphate was proving beneficial to many

> victims at the Carbide chemical disaster at Bhopal,

> but Carbide's toxicologists put out a statement saying

> that sodium thiosulphate should not be used.

>

> The success of sodium thiosulphate probably would

> have indicated cyanide poisoning (Hydrogen cyanide is

> one of the by-products of the methyl-isocyanate

> reaction that led to the disaster) and many people

> assumed that the company feared the word 'cyanide'.

>

> In fact methyl-isocyanate is 500 times more toxic than

> hydrogen cyanide and the real reason for suppressing

> the use of sodium thiosulphate was that its efficacy

> proved Carbide's poisons had crossed the blood-brain

> barrier, a fact which had far reaching medical

> consequences and could have exposed the company to

> huge compensation claims. As a result of the

> discontinuation of sodium thiosulphate treatment,

> countless lives were lost that could have been saved.

> These deaths were in effect knowingly caused by the

> company.[xxiii]

>

> Sodium thiosulfate detoxifies the toxic chemical

> waste dump in the liver.

>

> The key about sodium thiosulfate is that it reacts

> with oxidizing chemicals and neutralizes them so they

> will pass out of your body.

>

> It is also an effective agent to cleanse your liver by

> detoxification. When sodium thiosulfate is applied to

> tap water it offers the instant removal of chlorine

> thus it is ideal for treating tap water as well as

> distilled and reverse osmosis water.

>

> It is best to try to make in small quantities like

> one or two gallon of it first and see how it works. If

> it doesn't taste bad you are probably ok with the

> amount but if it doesn't taste that well you can

> reduce the amount you put in. Initially mix sodium

> thiosulfate one part powder to nine parts water. It is

> best to assume the sodium thiosulfate is at 10%

> concentration.

>

> However most commercial products are 5% but it is best

> to make your figures conservative and assume it to be

> a 10% solution so you don't use too much of the sodium

> thiosulfate.

>

> Pharmaceutical companies do not want you to discover

> that this chemical also cures a lot of human

> conditions as it will lower sales of other more

> expensive drugs.

>

> One drop per 8 oz glass would work out to about 4

> drops per liter. So that comes down to 4 drops per

> liter or 16 drops per gallon but it is best to start

> on the low side of 2 drops per liter or even less at

> first. This is the minimum amount in which plant

> growth, and hence possibly human health is affected.

> For healthy people 4 to eight drops per gallon is

> appropriate. People with serious illness will probably

> want to find a doctor who can apply it intravenously.

>

> Sodium thiosulfate is very inexpensive and is a

> medical healing substance that no one can make much

> money off of. Medical authorities can call it a drug

> all they want but all you have to do is go down to

> your local pet store and buy some.

>

> One can buy sodium thiosulfate from a pharmaceutical

> company by

> prescription only for:

> 120 ml $19.99

>

> 360 ml $52.99

>

> 480 ml $70.66

>

> 600 ml $88.32

>

> 720 ml $105.98

>

> Or:

> 1 LITER 9.00 10 percent solution

> 1 LITER 8.00 5 percent solution

> 500 Grams Crystal 7.00 2.5 KG Crystal 21.10 From

> you chemical supply house.[xxv] Or Go to your local

> pet shop

>

>

>

> Topical Applications: Sodium thiosulfate is

> present at 8% in lotion formulations to treat acne.

> Other lotions, containing 25% sodium thiosulfate, are

> used for treating ringworm, a fungal infection (Tinea)

> and may be applied twice daily to affected and

> susceptible skin for at least a week to many months

> until complete control is achieved.

>

> Dosing - The dose of sodium thiosulfate will be

> different for different patients.

>

> The standard dose of sodium thiosulfate for treatment

> of cyanide poisoning in humans is an IV administration

> of 50 milliliters (mL) of a 250 mg/mL (25%) solution.

>

> Patients also have been administered 50 mL of a 50%

> sodium thiosulfate solution without adverse effects.

>

> Sodium thiosulfate administered IV at 150-200 mg/kg

> over a period of 15 minutes, is part of the therapy to

> treat suspected cyanide toxicity from administration

> of sodium nitroprusside. The lethal dose of sodium

> thiosulfate when given at intravenous doses to rats is

> greater than 2.5

> g/kg.

>

> For use with cisplatin (a cancer medicine):

>

> Adults and teenagers-The first dose, given just

> before the cancer medicine, is usually 4 grams per

> square meter of body surface area, injected into a

> vein. The second dose is started at the same time as

> the cancer medicine. It is usually 12 grams per square

> meter of body surface area, injected into a vein over

> a period of six hours.

>

> For cyanide poisoning:

>

> Adults and teenagers-The usual dose is 12.5 grams

> injected into a vein at a rate of 0.625 to 1.25 grams

> (2.5 to 5 milliliters [mL]) per minute. Children-The

> usual dose is 412.5 milligrams (mg) per kilogram (kg)

> (187 mg per pound) of body weight or 7 grams per

> square meter of body surface area injected into a vein

> at a rate of 0.625 to 1.25 grams (2.5 to 5 mL) per

> minute.

>

> Pharmacokinetics - Sodium thiosulfate is relatively

> poorly absorbed from the GI tract. Patients only

> absorbed 20-25% of the oral dose.

>

> When administered intravenously, it is distributed in

> the extracellular fluid and then rapidly excreted via

> the urine. Sodium thiosulfate is known to be a strong

> diuretic. Following IV administration of sodium

> thiosulfate, peak thiosulfate concentrations were

> obtained 5 minutes after injection. The half-life of

> the distribution phase was 23 minutes while that of

> the elimination phase was 182 minutes.

>

> Contraindications/Precautions/Reproductive Safety -

> There are no absolute contraindications to the use of

> the drug. Safe use during pregnancy has not been

> established; use when benefits outweigh the potential

> risks.

>

> Adverse Effects/Warnings - The drug is non-toxic.

> Studies have shown that excess sodium thiosulfate

> beyond endogenous levels of thiosulfate is rapidly

> cleared from the body and there are no cumulative

> effects.

>

> According to the EPA, long term treatment of patients

> with a variety of illnesses has shown that ingestion

> of low levels of sodium thiosulfate is a non-toxic and

> safe therapeutic agent.

>

> A patient with renal tubular acidosis-I was treated

> for 9 years with sodium thiosulfate, 15-20 mmol daily

> (orally), to control nephrocalcinosis. During this

> time period, there were no treatment-related adverse

> effects, nephrocalcinosis did not worsen, and renal

> function improved.

>

> Large doses by mouth may cause profuse diarrhea.

> Injectable forms should be given slowly IV. Use with

> caution in conditions of high blood pressure, and in

> conditions that cause fluid retention, such as liver

> disease, heart failure, kidney disease or toxaemia of

> pregnancy.

>

> Allergies to sulfate may contradict use. Hamsters

> receiving IP injections of sodium thiosulfate at 1,600

> mg/kg every other day until five injections were

> completed showed no ill effects from sodium

> thiosulfate.

>

> Along with its needed effects, a medicine may cause

> some unwanted effects. Although not all of these side

> effects may occur, if they do occur they may need

> medical attention. Check with your doctor immediately

> if any of the following side effects occur:

>

> Symptoms of overdose

>

> Agitation; blurred vision; hallucinations (seeing,

> hearing, or feeling things that are not there); mental

> changes; muscle cramps; nausea and vomiting; pain in

> the joints; ringing in the ears.

>

> Sodium Thiosulfate for Injection 25% (250 mg/ml) in

> 50 ml vials.

>

> Long Term Use:

>

> One patient, in addition to sodium bicarbonate and

> potassium gluconate, received sodium thiosulphate for

> 18 years at a dose of 15-20 mmol daily from a 2 M

> solution (10 mmol/5 ml). This therapy seemed to

> prevent any further deposition of calcium and has been

> associated with stable renal function for the past 2

> decades.[xxiv]

>

> Special Note for people who live in areas where they

> are already using chloramines in public water

> supplies.

>

> One known method for the removal of chloramine from

> water supplies is the reduction of chloramine by the

> action of sodium thiosulfate. However, the ammonia

> which is liberated from the reduction of the

> chloramine cannot be bound by sodium thiosulfate.

>

> The removal of ammonia is also of great importance to

> aquarists and fish breeders since it is known that

> ammonia is also a strong fish poison.

>

> Therefore, when an agent such as sodium thiosulfate is

> used to treat chloramine, there is also the additional

> need to use an active agent such as zeolites to adsorb

> the ammonia.

>

> Heavy metals, on the other hand, can be bound by

> thiosulfate ions to give thiosulfate complexes, their

> toxicity thereby being reduced.[xxvi]

>

[Shivambu]

Thank you for this valuable information.I will put it in to practice right away.Also check Vit C and water de chlorination.Please send me more on this health subject.

God bless