Calcium D-glucarate Inhibits Estrogen - dependent Cancers]

[Guest guest]

> Calcium D-glucarate inhibits Estrogen-dependent Cancers

>

> Q. I have seen advertisements for a supplement containing calcium

> D-glucarate to prevent breast cancer.

>

> How does this product work?

>

> A. Calcium D-glucarate is a natural substance used to inhibit an

> enzyme in

> certain bacteria that reside in the gut - beta-glucuronidase.

>

> One of the key ways in which the body gets rid of hormones like estrogen

> is via attaching glucuronic acid to the hormone in the liver and then

> excreting this complex in the bile.

>

> Beta-glucuronidase is a bacterial enzyme that uncouples (breaks) the

> bond between excreted hormone and glucuronic acid.

>

> When beta-glucuronidase breaks the bond, the freed hormone is available

> to be reabsorbed back into the body instead of being excreted.

>

> An elevated beta-glucuronidase activity is associated with an increased

> risk for various cancers, particularly hormone-dependent cancers like

> breast and prostate as well as colon cancer.

>

> By taking calcium D-glucarate, the activity of beta-glucuronidase is

> inhibited.

>

> As a result the body is better able to get rid of excess hormones like

> estrogen.

>

> Since most breast cancers are dependent upon estrogen, researchers at

> M.D. Anderson Cancer Center, Memorial Sloan-Kettering Cancer Center, and

> other major cancer centers began conducting research with calcium

> D-glucarate in the prevention and treatment of breast cancer.

>

> The preliminary results are quite encouraging. The recommended daily

> dosage for prevention is 200 to 400 mg. Higher dosages (i.e., 400 to

> 1,200 mg) may be necessary for individuals with existing breast cancer.

>

> www.doctormurray.com