PANCREATIN,What is it?

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PANCREATIN

 

What is it?

 

Pancreatin is a digestive enzyme that is used to supplement loss of or

low digestive enzymes. It is also claimed to help with food allergies,

celiac disease, autoimmune disease, cancer, and weight loss.

 

Other names for Pancreatin include: Pancreatinum and pancreatic enzymes.

 

If any information in this leaflet causes you special concern or if you

want additional information about your medicine and its use, check with

your doctor, pharmacist or nurse. Keep this and all other medicine away

from children. Never share your medicine with others.

 

Before Using:

 

Tell your doctor, pharmacist or nurse if you …

 

* are allergic to any medicine, either prescription, nonprescription

(OTC), or dietary supplement;

* are pregnant or intend to become pregnant while using this medicine;

* are breastfeeding;

* are taking any other prescription or nonprescription (OTC)

medicine or dietary supplement;

* have any other medical problems, especially heart or blood vessel

disease.

 

How to take and store:

 

How much to take - there are many doses for this medicine. Below you can

see the most common ones. If your health problem is not listed or the

dose is not given for a product you want to use, please check with your

doctor, pharmacist or nurse for the right dose.

 

Dosage:

 

* GENERAL USE: 500 to 1000 milligrams with each meal, by mouth (1,2)

* SHINGLES: 500 to 1000 milligrams (10x USP pancreatic enzyme

product), three times daily, 10 to 20 minutes before a meal, by

mouth (1)

* WEIGHT LOSS: 500 to 1000 milligrams (10x USP pancreatic enzyme

product), three times daily, 10 to 20 minutes before a meal, by

mouth (1)

* MULTIPLE SCLEROSIS: 500 to 1000 milligrams (10x USP pancreatic

enzyme product), three times daily, 10 to 20 minutes before a

meal, by mouth (1)

 

To store this medicine:

 

Keep out of reach of children. Store away from heat and direct light. Do

not store your medicine in the bathroom, near the kitchen sink, or in

other damp places. Heat or moisture may cause the medicine to break

down. Do not keep outdated medicine or medicine no longer needed. Be

sure that any discarded medicine is out of reach of children.

 

Drug and Food Interactions:

 

Do not take Pancreatin without talking to your doctor first if you are

taking:

 

* Acarbose (3)

* Cimetidine (4-6)

* Famotidine (4-6)

* Folic Acid (7)

* Migiltol (8)

* Nizatidine (4-6)

* Rantidine (4-6)

 

Warnings:

 

* If you are pregnant or breastfeeding, you should not take

Pancreatin without first consulting your health care professional.

* If you have gallstones, or possible blockage of gallbladder duct,

you should not take Pancreatin without first consulting your

health care professional (9).

 

Possible Side Effects:

 

Side Effects That Should Be Reported to Your Doctor Immediately:

 

Stop taking this medicine and check with your doctor immediately if any

of the following side effects occur:

 

* You have trouble breathing; hives; your skin is itchy, swollen or

you have a rash. Your medicine may be causing these symptoms. This

may mean you are allergic to your medicine.

 

Other Possible Side Effects:

 

* Diarrhea or soft stools have been reported (2).

 

Other side effects not listed above may also occur in some patients. If

you notice any other side effects, check with your doctor, pharmacist or

nurse.

 

References:

 

1. Murray, MT, Pizzorno J: Encyclopedia of Natural Medicine 2^nd ed.

Prima Publishing, Rocklin, CA, 1998.

2. Product Information: Entozyme ®, pancreatin. AH Robins Company,

Richmond, VA, 1990.

3. Product Information: Precose ®, acarbose. Bayer Corporation, West

Have, CT, 1998.

4. Regan PT, Malagelada JR, DiMagno EP et al: cimetidine as an adjunct

to oral enzymes in the treatment of malabsorption due to pancreatic

insufficiency.

5. Reagan PT, Malagelada JR, DiMagno EP et al: Comparative effects of

antacids, cimetidine and enteric coating on the theapeutic response to

oral enzymes in severe pancreatic insufficiency. N Engl J Med 1977;

297:854-858.

6. Sorkin EM & Darvey DL: Review of cimetidine drug interactions. Drug

Intell Clin harm 1983;17:110-120.

7. Russell RM, Dutta SK, Oaks EV et al: Impairment of folic acid

absorption by oral pancreatic extracts. Dig Dis Sci 1980;25:369-373.

8. Product Information: Glyset ™, miglitol. Bayer Corporation, West

Haven, CT, 1996.

Anon: Pancreatin (monograph). Micromedex ® Health Care Series vol 102, 1997.

 

PE0337

 

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Authored By: MICROMEDEX

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Last Reviewed 1/04 by Healthyroads Editorial Staff

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