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Misty wrote:

 

>ANOTHER DEAD MICROBIOLOGIST

>http://www.rumormillnews.com/cgi-bin/forum.cgi?read=56565

>Posted By: TruthPassion <Send E-Mail>

>Friday, 1 October 2004, 12:56 a.m.

>

>How many microbiologists are dead now? TP

>

>* * * * * * * * * * *

>

>Professor John Clark

>(Filed: 31/08/2004)

>

>Professor John Clark, who has died aged 52, was an expert in animal science

>and biotechnology and the Director of the Roslin Institute, near Edinburgh,

>where he developed techniques for the genetic modification of livestock;

>this work paved the way for the birth, in 1996, of Dolly the sheep, the

>first animal to have been cloned from an adult.

>

>In 1985 Clark joined what was then known as the Animal Breeding Research

>Organisation in Edinburgh where he was put in charge of a project to produce

>human proteins (which could be used in the treatment of human diseases) in

>sheep's milk. Clark and his team focused their study on the production of

>the alpha-I-antitrypsin protein, which is used for treatment of cystic

>fibrosis.

>

>The production of human proteins in another animal's milk requires the

>ability to manipulate DNA and introduce human gene sequences into animal

>embryos. At the time, such genetic modification was a great technical

>challenge. Thus when, in 1990, Clark announced the birth of Tracy, the first

>sheep to produce large quantities of human protein in her milk, it was a

>significant milestone in the development of transgenic technologies. It also

>helped to establish the Roslin Institute as a leading centre for research in

>animal biotechnology.

>

>During the 1990s Clark continued to develop cloning techniques and to work

>on the production of precise genetic changes in animals other than mice. He

>and his colleagues were the first to produce a large animal from which a

>specific gene had been removed (a prion protein gene from a sheep). Then in

>1996, building on much of Clark's work, scientists at Roslin successfully

>transplanted the DNA of an adult sheep to an unfertilised egg cell which had

>been previously emptied of its own genetic material. The result was the

>birth of Dolly the sheep.

>

>John Clark was born at Blackpool on September 18 1951, but was brought up in

>Lincolnshire. He was educated at Barton Grammar School, Lincolnshire, before

>going on to Christ's College, Cambridge, where he read Zoology. In 1975 he

>took an M Sc from the University of Western Ontario, where he studied

>development in the mud snail.

>

>After a year spent travelling around America with his wife, Helen, Clark

>returned to Britain where he began working as a molecular biologist,

>completing a study on human satellite DNA for the Medical Research Council

>Clinical and Population Cytogenetics Unit in Edinburgh, by which he was

>awarded a PhD in 1982.

>

>His first post-doctoral appointment was to study genes that function in the

>liver of mice with John Bishop in the Institute of Genetics, at Edinburgh

>University.

>

>At the Roslin Institute Clark combined his work on the development of

>transgenic livestock with the establishment of the institute's research

>programme on human embryonic stem cells. His appointment as director of the

>institute in August 2003 was greeted with widespread approval.

>

>At the time of his death he was working to derive liver cells and neurones

>from human embryonic stem cells for use in the testing of new drugs and in

>the treatment of Parkinson's disease, stroke and spinal cord injury.

>

>Read on at:

>http://www.telegraph.co.uk/news/main.jhtml?xml=/news/2004/08/31/db3103.xml & s

>Sheet=/portal/2004/08/31/ixportal.html

>

>

>

>

>

 

 

ANOTHER DEAD MICROBIOLOGIST

http://www.rumormillnews.com/cgi-bin/forum.cgi?read=56565

Posted By: TruthPassion <Send E-Mail>

Friday, 1 October 2004, 12:56 a.m.

 

How many microbiologists are dead now? TP

 

* * * * * * * * * * *

 

Professor John Clark

(Filed: 31/08/2004)

 

Professor John Clark, who has died aged 52, was an expert in animal science

and biotechnology and the Director of the Roslin Institute, near Edinburgh,

where he developed techniques for the genetic modification of livestock;

this work paved the way for the birth, in 1996, of Dolly the sheep, the

first animal to have been cloned from an adult.

 

In 1985 Clark joined what was then known as the Animal Breeding Research

Organisation in Edinburgh where he was put in charge of a project to produce

human proteins (which could be used in the treatment of human diseases) in

sheep's milk. Clark and his team focused their study on the production of

the alpha-I-antitrypsin protein, which is used for treatment of cystic

fibrosis.

 

The production of human proteins in another animal's milk requires the

ability to manipulate DNA and introduce human gene sequences into animal

embryos. At the time, such genetic modification was a great technical

challenge. Thus when, in 1990, Clark announced the birth of Tracy, the first

sheep to produce large quantities of human protein in her milk, it was a

significant milestone in the development of transgenic technologies. It also

helped to establish the Roslin Institute as a leading centre for research in

animal biotechnology.

 

During the 1990s Clark continued to develop cloning techniques and to work

on the production of precise genetic changes in animals other than mice. He

and his colleagues were the first to produce a large animal from which a

specific gene had been removed (a prion protein gene from a sheep). Then in

1996, building on much of Clark's work, scientists at Roslin successfully

transplanted the DNA of an adult sheep to an unfertilised egg cell which had

been previously emptied of its own genetic material. The result was the

birth of Dolly the sheep.

 

John Clark was born at Blackpool on September 18 1951, but was brought up in

Lincolnshire. He was educated at Barton Grammar School, Lincolnshire, before

going on to Christ's College, Cambridge, where he read Zoology. In 1975 he

took an M Sc from the University of Western Ontario, where he studied

development in the mud snail.

 

After a year spent travelling around America with his wife, Helen, Clark

returned to Britain where he began working as a molecular biologist,

completing a study on human satellite DNA for the Medical Research Council

Clinical and Population Cytogenetics Unit in Edinburgh, by which he was

awarded a PhD in 1982.

 

His first post-doctoral appointment was to study genes that function in the

liver of mice with John Bishop in the Institute of Genetics, at Edinburgh

University.

 

At the Roslin Institute Clark combined his work on the development of

transgenic livestock with the establishment of the institute's research

programme on human embryonic stem cells. His appointment as director of the

institute in August 2003 was greeted with widespread approval.

 

At the time of his death he was working to derive liver cells and neurones

from human embryonic stem cells for use in the testing of new drugs and in

the treatment of Parkinson's disease, stroke and spinal cord injury.

 

Read on at:

http://www.telegraph.co.uk/news/main.jhtml?xml=/news/2004/08/31/db3103.xml & s

Sheet=/portal/2004/08/31/ixportal.html

 

 

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Messages In This Thread

 

 

ANOTHER DEAD MICROBIOLOGIST (views: 1010)

TruthPassion -- Friday, 1 October 2004, 12:56 a.m.

MAYBE NOT ALL ARE DEAD... (views: 463)

WhiteRaven -- Friday, 1 October 2004, 7:42 a.m.

OH YES, THEY ARE. THEY HAVE OUTLIVED THEIR USEFULNESS (views: 317)

IZAKOVIC -- Friday, 1 October 2004, 11:44 a.m.

 

 

 

 

 

 

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