Guest guest Posted August 28, 2000 Report Share Posted August 28, 2000 Dear William and Mariam, Greetings... Medical Information: Osteoporosis is a progressive decrease in the density of bones that weakens them and makes them more likely to fracture. To maintain bone density, the body requires an adequate supply of calcium and other minerals and must produce the proper amounts of several hormones, such as parathyroid hormone, growth hormone, calcitonin, estrogen in women, and testosterone in men. Also, an adequate supply of vitamin D is needed to absorb calcium from food and incorporate it into bones. Bones progressively increase in density until a maximum density is reached, around age 30. After that, bones slowly decrease in density. If the body isn't able to regulate the mineral content of bones, they become less dense and more fragile, resuslting in osteoporosis. PRANIC HEALING TREATMENT: 1. General Sweeping several times. 2. Cleansing the Blood Technique (APH book, p. 97 & 98) 3. Cleansing the Internal Organs Technique (APH book, p.95) 4. Sweep the affected part with LWG & LWO. Avoid using orange near the head area. Energize with LWG, LWB, then more of LWV. 5. Sweep legs and arms with LWG & LWO. Energize affected joints with LWG, LWB, & LWO. Once condition has improved, energize with LWG then with more LWV. 6. Energize other chakras on the arms and legs with LWR. 7. Sweep meng mein. 8. Sweep kidneys with LWG & LWO. Energize with WHITE. 9. Sweep basic and navel chakras with LWG & LWO. Energize with LWR. 10. Sweep sex chakras with LWG. Energize with WHITE. 11. Sweep spleen. Energize with WHITE. Do not energize if patient has hypertension. 12. Sweep front and back heart. Energize the back heart with LWG, then more of LWV. 13. Sweep throat and secondary throat chakras with LWG. Energize with LWG, LWB, then LWV. 14. Sweep the ajna, forehead, crown and back head. Energize with LWG, then more of LWV. 15. Repeat treatment 3 times a week. Treatment may last several months... 16. PREVENTION IS MORE IMPORTANT... Love and light, MasterFe -------- At 07:40 PM 8/26/00 -0000, you wrote: >Dear Master Fe, > >First, we would like to thank you and the organization for creating >the website and e-mail lists. We have been practicing Pranic Healing, >etc. for six years and have hoped something like this would develop. > >We presently have a client who was been diagnosed with Osteoporosis. >Do you have any suggestions as to how we might assist he with this >condition. > >Will***Love***Light >William and Mariam > ------------------- " Pranic Healing is not intended to replace orthodox medicine, but rather to complement it. If symptoms persist or the ailment is severe, please consult immediately a medical doctor and a certified pranic healer. " - GRAND MASTER CHOA KOK SUI ------------------- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2004 Report Share Posted December 20, 2004 Reply-- I take 2 red deer velvet capsules in the am and two each night, and I am 84 years old, with the same height that I had at age 50... my source is easily obtained as my daughter ( A DVM) in is the deer farming business.. This was also helped me with a quick recovery from a dislocated shoulder last summer and shingles -- and both were problems the last week of July, but by Oct 15, was back to normal... muriel schmidt, northwest arkansas... 12/20/2004, you wrote: " bta1012003 " <bta101 Dear members: Can anyone recommend what one can do to slow down the onset of osteoporosis? What has work for you? Thanks in advance, bta ========================================== bta, About six or so years ago I was diagnosed with osteopenia, which is almost osteoporosis. At the time I was drinking lots of milk (3 big glasses a day), eating ice cream, cheese, actually all dairy, and taking my calcium pills. Just because that’s what you hear that you’re supposed to do to prevent bone problems. How wrong I was! And how wrong that advice is! My doctor at the time told me that I should eat more dairy and take more calcium pills. I decided not to follow doctor orders and went completely opposite of what he told me. I eliminated dairy (maybe I eat dairy a couple times a month now), I eliminated my calcium pills (which are nothing more than isolated, synthetically made junk), I eliminated 99% of my meat consumption (I eat meat only a couple times a month). Meats are very acid forming in your body, and the way your body tries to get rid of all that acid is with calcium – and guess where your body finds a store of calcium to use - your bones and teeth. I also added a lot of calcium rich veggies to my diet, I added whole food supplements that are naturally balanced like food is, and I also added a red yeast rice capsule which is specifically for bone health. My last bone scan showed that my bones have dramatically gotten better – my 58 year old body has 25 year old bones, according to the scan. Carol ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Organic, wholefood, supplements provide nutrients essential for the health of people, pets and plants. http://www.bluegreensolutions.com «¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤» § - PULSE ON WORLD HEALTH CONSPIRACIES! § Subscribe:......... - To :.... - Any information here in is for educational purpose only, it may be news related, purely speculation or someone's opinion. Always consult with a qualified health practitioner before deciding on any course of treatment, especially for serious or life-threatening illnesses. **COPYRIGHT NOTICE** In accordance with Title 17 U.S.C. Section 107, any copyrighted work in this message is distributed under fair use without profit or payment to those who have expressed a prior interest in receiving the included information for non-profit research and educational purposes only. http://www.law.cornell.edu/uscode/17/107.shtml Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2004 Report Share Posted December 20, 2004 Exercise. put stress on your bones to adapt with responding to the stress with the deposition of calcium. - Carol Minnick Monday, December 20, 2004 2:14 PM Osteoporosis "bta1012003" <bta101 Dear members: Can anyone recommend what one can do to slow down the onset of osteoporosis? What has work for you? Thanks in advance, bta ========================================== bta, About six or so years ago I was diagnosed with osteopenia, which is almost osteoporosis. At the time I was drinking lots of milk (3 big glasses a day), eating ice cream, cheese, actually all dairy, and taking my calcium pills. Just because that’s what you hear that you’re supposed to do to prevent bone problems. How wrong I was! And how wrong that advice is! My doctor at the time told me that I should eat more dairy and take more calcium pills. I decided not to follow doctor orders and went completely opposite of what he told me. I eliminated dairy (maybe I eat dairy a couple times a month now), I eliminated my calcium pills (which are nothing more than isolated, synthetically made junk), I eliminated 99% of my meat consumption (I eat meat only a couple times a month). Meats are very acid forming in your body, and the way your body tries to get rid of all that acid is with calcium – and guess where your body finds a store of calcium to use - your bones and teeth. I also added a lot of calcium rich veggies to my diet, I added whole food supplements that are naturally balanced like food is, and I also added a red yeast rice capsule which is specifically for bone health. My last bone scan showed that my bones have dramatically gotten better – my 58 year old body has 25 year old bones, according to the scan. Carol ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Organic, wholefood, supplements provide nutrients essential for the health of people, pets and plants. http://www.bluegreensolutions.com «¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§ - PULSE ON WORLD HEALTH CONSPIRACIES! §Subscribe:......... - To :.... - Any information here in is for educational purpose only, it may be news related, purely speculation or someone's opinion. Always consult with a qualified health practitioner before deciding on any course of treatment, especially for serious or life-threatening illnesses.**COPYRIGHT NOTICE**In accordance with Title 17 U.S.C. Section 107,any copyrighted work in this message is distributed under fair use without profit or payment to those who have expressed a prior interest in receiving the included information for non-profit research and educational purposes only. http://www.law.cornell.edu/uscode/17/107.shtml Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2004 Report Share Posted December 20, 2004 That is wonderful Carol. Thank you so much for this info. I have not known of any osteoporosis in my family but I do have friends that are facing the problem and now I have a direction to send them. Sharing does really make a difference. ElizabethCarol Minnick <carolminnick wrote: "bta1012003" <bta101 Dear members: Can anyone recommend what one can do to slow down the onset of osteoporosis? What has work for you? Thanks in advance, bta ========================================== bta, About six or so years ago I was diagnosed with osteopenia, which is almost osteoporosis. At the time I was drinking lots of milk (3 big glasses a day), eating ice cream, cheese, actually all dairy, and taking my calcium pills. Just because that’s what you hear that you’re supposed to do to prevent bone problems. How wrong I was! And how wrong that advice is! My doctor at the time told me that I should eat more dairy and take more calcium pills. I decided not to follow doctor orders and went completely opposite of what he told me. I eliminated dairy (maybe I eat dairy a couple times a month now), I eliminated my calcium pills (which are nothing more than isolated, synthetically made junk), I eliminated 99% of my meat consumption (I eat meat only a couple times a month). Meats are very acid forming in your body, and the way your body tries to get rid of all that acid is with calcium – and guess where your body finds a store of calcium to use - your bones and teeth. I also added a lot of calcium rich veggies to my diet, I added whole food supplements that are naturally balanced like food is, and I also added a red yeast rice capsule which is specifically for bone health. My last bone scan showed that my bones have dramatically gotten better – my 58 year old body has 25 year old bones, according to the scan. Carol ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Organic, wholefood, supplements provide nutrients essential for the health of people, pets and plants. http://www.bluegreensolutions.com «¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§ - PULSE ON WORLD HEALTH CONSPIRACIES! §Subscribe:......... - To :.... - Any information here in is for educational purpose only, it may be news related, purely speculation or someone's opinion. Always consult with a qualified health practitioner before deciding on any course of treatment, especially for serious or life-threatening illnesses.**COPYRIGHT NOTICE**In accordance with Title 17 U.S.C. Section 107,any copyrighted work in this message is distributed under fair use without profit or payment to those who have expressed a prior interest in receiving the included information for non-profit research and educational purposes only. http://www.law.cornell.edu/uscode/17/107.shtml Are you looking for your soulmate? Would you like to make friends,or find a pen pal and make money at the same time. This is brand new so go to http://loveinminutes.com/affiliate.php?profileid=Seajewell and check it out. It is Free and lots of Fun!!Did you know that our bodies have the capabilities to heal through proper nutrition? You need raw wholefoods, hydration, exercise and lots of sunshine. Go to www.naturalhealth4meandu.wholefoodfarmacy.com and start your healthy new life with "Orgonic" Raw Wholefoods!! Mail - Easier than ever with enhanced search. Learn more. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2004 Report Share Posted December 20, 2004 Use ORMUS. See the testimonials at our website... On Mon, 20 Dec 2004 15:12:33 -0500 <DrLance wrote: > Exercise. put stress on your bones to adapt with >responding to the stress with the deposition of calcium. >- > Carol Minnick > > Monday, December 20, 2004 2:14 PM > Osteoporosis > > > " bta1012003 " <bta101 > > Dear members: > > Can anyone recommend what one can do to slow down the >onset of osteoporosis? What has work for you? Thanks in >advance, bta > > ========================================== > > > > bta, > > > > About six or so years ago I was diagnosed with >osteopenia, which is almost osteoporosis. At the time I >was drinking lots of milk (3 big glasses a day), eating >ice cream, cheese, actually all dairy, and taking my >calcium pills. Just because that's what you hear that >you're supposed to do to prevent bone problems. How >wrong I was! And how wrong that advice is! My doctor at >the time told me that I should eat more dairy and take >more calcium pills. I decided not to follow doctor >orders and went completely opposite of what he told me. > I eliminated dairy (maybe I eat dairy a couple times a >month now), I eliminated my calcium pills (which are >nothing more than isolated, synthetically made junk), I >eliminated 99% of my meat consumption (I eat meat only a >couple times a month). Meats are very acid forming in >your body, and the way your body tries to get rid of all >that acid is with calcium - and guess where your body >finds a store of calcium to use - your bones and teeth. > I also added a lot of calcium rich veggies to my diet, I >added whole food supplements that are naturally balanced >like food is, and I also added a red yeast rice capsule >which is specifically for bone health. My last bone scan >showed that my bones have dramatically gotten better - my >58 year old body has 25 year old bones, according to the >scan. > > > > Carol > > ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ > > Organic, wholefood, supplements provide nutrients >essential for the > > health of people, pets and plants. >http://www.bluegreensolutions.com > > > > > > «¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤» > > § - PULSE ON WORLD HEALTH >CONSPIRACIES! § > > Subscribe:......... >- > To :.... >- > > Any information here in is for educational purpose >only, it may be news related, purely speculation or >someone's opinion. Always consult with a qualified health >practitioner before deciding on any course of treatment, >especially for serious or life-threatening illnesses. > **COPYRIGHT NOTICE** > In accordance with Title 17 U.S.C. Section 107, > any copyrighted work in this message is distributed >under fair use without profit or payment to those who >have expressed a prior interest in receiving the included >information for non-profit research and educational >purposes only. > http://www.law.cornell.edu/uscode/17/107.shtml > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2004 Report Share Posted December 21, 2004 In a message dated 12/21/2004 5:42:51 A.M. Eastern Standard Time, writes: Dear members:Can anyone recommend what one can do to slow down the onset of osteoporosis?What has work for you? Thanks in advance, bta I totally agree with what Carol said. It is excellent advice. I, too, have dramatically changed my diet, and my bone density has improved dramatically. A variety of whole foods - fruits, vegs, whole grains, nuts, and seeds. Basically, that is a macrobiotic diet. I think that if we stay natural in our diets, that is the way our bodies were meant to work. We basically have cave men bodies. Our bodies were meant to absorb nutrients through food - not through chemicals, food that has been adulterated or processed, or food that has been "refined". We can get the nutrients needed for healthy living from whole food. We do not need food to be "enriched". The reason that food is "enriched", is that the nutrients are first taken out, and then need to be replaced. Take, for example, enriched flour. It is bleached to make it white, and during the processing and refinement, all of the natural nutrients are removed. Then, non-natural nutrients are added in the enrichment process. The same thing happens with sugar, but it is not enriched. The bleaching process is carcinogenic. You don't have to stop living. There are ways to make just about everything healthy. There are now cups of all natural soup that have 29 whole foods in each cup - just add water. Health bars that have 24 whole foods per bar. They are convenient. I guess the one thing technology has done is to give us convenience. We need the whole grains, we just don't need the bleached, processed, and refined ones. It actually is not necessary to cut out all flour items - pancakes, waffles, biscuits, muffins, cookies, etc. I make them with a whole grain biscuit mix and a whole grain muffin mix. I also take whole food vitamins. It only stands to reason, that if our bodies are designed to absorb our nutrients through food, but our food doesn't have enough nutrients in them any more, that we should supplement with whole food supplements. Barb RN, Health and Wellness Consultant*************************************Energy technology products, help for sleep & discomfort Energized air treatment, w/ 5 filtering technologies Energized Water to oxygenate & alkalize, w/ coral calciumPackaged whole foods that are organic, non-GMO and macrobioticNatural whole food dietary supplementsWeighted exercise shoes - increase metabolism, burn calories, toneRife technology, rebounders, Transfer Factor Pluswhole colostrum, cesium, T-Plus Aloe (pp. 424- 431 in "Politics in Healing")Natural & non chemical makeup, shampoo, cleansers************************************** Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2004 Report Share Posted December 21, 2004 REVERSING AND PREVENTING OSTEOPOROSIS Several studies available here show definite bone remineralisation in response to HGH being normalized to youthful values. HGH is an absolute requirement for cell growth to occur, and low levels impair healing throughout the body. http://mmbers.shaw.ca/patriciagilbert/ Bowel bacteria must also be in order so the bowel acidity is adequate to ionize minerals for absorption; bowel dysbiosis due to poor diet is one cause of osteoporosis. I have the definitive page on bowel dysbiosis and how to reverse it on my web site; sorry you'll have to find it with a Google search as I can't post a personal link. The trace elements trontium and boron, and vitamin C are also required along with the calcium and magnesium everyone knows about. The above facets of bone mineralisation are unexplored in many people; that is what makes me successful as a consultant on this topic. Because toxin load also impairs cell growth, I usually also coach people in detoxification methods. regards, Duncan Crow Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 21, 2004 Report Share Posted December 21, 2004 reply-- I am 84 and have the same height as at 60, so think I have this thing licked. However, it might run in families, and I have a long lived gene that is the best " kind of medicine " one can get... But, just to play safe, I use the deer velvet capsules, nothing added, all natural, and 2 in the am and 2 in the pm got my dislocated shoulder back in shape, and got rid of the shingles all in the same 3 monts... a record for anyone, especially at my age... We Swedes are a tough bunch, however, and do not need all that prescription and medicare business.. Its the good that die young, and you see who is left standing?? We stubborn Swedes... haha. . Have a good one. ( what ever you want to be having.) check it out. www. by2kok.com muriel of nw arkansas. At 10:01 AM 12/21/2004, you wrote: In a message dated 12/21/2004 5:42:51 A.M. Eastern Standard Time, writes: Dear members: Can anyone recommend what one can do to slow down the onset of osteoporosis? What has work for you? Thanks in advance, bta I totally agree with what Carol said. It is excellent advice. I, too, have dramatically changed my diet, and my bone density has improved dramatically. A variety of whole foods - fruits, vegs, whole grains, nuts, and seeds. Basically, that is a macrobiotic diet. I think that if we stay natural in our diets, that is the way our bodies were meant to work. We basically have cave men bodies. Our bodies were meant to absorb nutrients through food - not through chemicals, food that has been adulterated or processed, or food that has been " refined " . We can get the nutrients needed for healthy living from whole food. We do not need food to be " enriched " . The reason that food is " enriched " , is that the nutrients are first taken out, and then need to be replaced. Take, for example, enriched flour. It is bleached to make it white, and during the processing and refinement, all of the natural nutrients are removed. Then, non-natural nutrients are added in the enrichment process. The same thing happens with sugar, but it is not enriched. The bleaching process is carcinogenic. You don't have to stop living. There are ways to make just about everything healthy. There are now cups of all natural soup that have 29 whole foods in each cup - just add water. Health bars that have 24 whole foods per bar. They are convenient. I guess the one thing technology has done is to give us convenience. We need the whole grains, we just don't need the bleached, processed, and refined ones. It actually is not necessary to cut out all flour items - pancakes, waffles, biscuits, muffins, cookies, etc. I make them with a whole grain biscuit mix and a whole grain muffin mix. I also take whole food vitamins. It only stands to reason, that if our bodies are designed to absorb our nutrients through food, but our food doesn't have enough nutrients in them any more, that we should supplement with whole food supplements. Barb RN, Health and Wellness Consultant ************************************* Energy technology products, help for sleep & discomfort Energized air treatment, w/ 5 filtering technologies Energized Water to oxygenate & alkalize, w/ coral calcium Packaged whole foods that are organic, non-GMO and macrobiotic Natural whole food dietary supplements Weighted exercise shoes - increase metabolism, burn calories, tone Rife technology, rebounders, Transfer Factor Plus whole colostrum, cesium, T-Plus Aloe (pp. 424- 431 in " Politics in Healing " ) Natural & non chemical makeup, shampoo, cleansers ************************************** «¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤»§«¤»¥«¤» § - PULSE ON WORLD HEALTH CONSPIRACIES! § Subscribe:......... - To :.... - Any information here in is for educational purpose only, it may be news related, purely speculation or someone's opinion. Always consult with a qualified health practitioner before deciding on any course of treatment, especially for serious or life-threatening illnesses. **COPYRIGHT NOTICE** In accordance with Title 17 U.S.C. Section 107, any copyrighted work in this message is distributed under fair use without profit or payment to those who have expressed a prior interest in receiving the included information for non-profit research and educational purposes only. http://www.law.cornell.edu/uscode/17/107.shtml Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2004 Report Share Posted December 22, 2004 How very interesting. Thank you very much for sharing your experience. I appreciate it. I will look for the red yeast rice capsule. Is this something a health food store would carry? bta > > About six or so years ago I was diagnosed with osteopenia, which is almost > osteoporosis. At the time I was drinking lots of milk (3 big glasses a > day), eating ice cream, cheese, actually all dairy, and taking my calcium > pills. Just because that's what you hear that you're supposed to do to > prevent bone problems. How wrong I was! And how wrong that advice is! My > doctor at the time told me that I should eat more dairy and take more > calcium pills. I decided not to follow doctor orders and went completely > opposite of what he told me. I eliminated dairy (maybe I eat dairy a couple > times a month now), I eliminated my calcium pills (which are nothing more > than isolated, synthetically made junk), I eliminated 99% of my meat > consumption (I eat meat only a couple times a month). Meats are very acid > forming in your body, and the way your body tries to get rid of all that > acid is with calcium - and guess where your body finds a store of calcium to > use - your bones and teeth. I also added a lot of calcium rich veggies to > my diet, I added whole food supplements that are naturally balanced like > food is, and I also added a red yeast rice capsule which is specifically for > bone health. My last bone scan showed that my bones have dramatically > gotten better - my 58 year old body has 25 year old bones, according to the > scan. > > Carol > ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ > Organic, wholefood, supplements provide nutrients essential for the > health of people, pets and plants. http://www.bluegreensolutions.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2004 Report Share Posted December 22, 2004 As we age, our immune system tends to move towards the pro-inflamatory Th2 arm, where many diseases related to inflamation begin to manifest and osteoporosis being one of them. The pro-inflamatory cytokinr IL-6 seems to play a prominent role in most of these diseases. I strongly believe that an anti-inflamatory diet together with immune modulating supplement will be of great help. Below is an abstract from: IMMUNE SYSTEM, EFFECTS ON THE ENDOCRINE SYSTEM Chapter 29 - Jason A. Berner, M.D., Dimitris A. Papanicolaou, M.D. March 11, 2003: CALCIUM METABOLISM AND THE IMMUNE SYSTEM Osteoporosis Osteoporosis is a disease of bone metabolism typically occurring in postmenopausal women, in which bone resorption is favored over bone formation. The two cells involved in dynamic bone metabolism are osteoblasts and osteoclasts. Osteoblasts function to lay down new bone and osteoclasts function to reabsorb old bone. Cytokines have been implicated in the pathogenesis of osteoporosis. Osteoblasts produce the cytokines IL-6 and IL-11 (78). In addition, many cytokines such as IL-1, IL-3, IL-6, IL-11, and TNF along with colony stimulating factors are implicated in osteoclast development (79-82). IL-6 plays a major role in osteoclast development and function. IL-6 is produced by both stromal cells and osteoblastic cells in response to stimulation by systemic hormones such as parathyroid hormone (PTH), PTH-related peptide (PTH-RP), thyroid hormones and 1,25-dihydroxyvitamin D3. Growth factors involved in resorption, such as transforming growth factor-ƒÒeta (TGF-ƒÒ), and other cytokines- like IL-1 and TNF- increase IL-6 production as well (83). IL-6 has been shown to stimulate osteoclast formation and bone resorption in fetal mouse bone in vitro (84, 85) and, along with IL-1, it stimulates bone resorption in vivo (86). Evidence has been shown to suggest that IL-6 influences not only immature osteoclasts but mature osteoclasts as well. Human osteoclastoma cells have receptors for IL-6, which stimulates the resorptive activity of these cells (87). Furthermore, IL-6 has been shown to play a role in the abnormal bone resorption observed with multiple myeloma (88), Paget's disease (89), rheumatoid arthritis (90), and Gorham-Stout disease (91). Effects of increased osteoclast-induced bone resorption are not solely reserved to IL-6, but IL-6 family cytokines- such as leukemia-inhibitory factor (LIF) - as well. It appears that LIF acts on osteoclasts indirectly via stimulating IL-6 release by osteoblasts, resulting in an increase in bone resorption (92). In postmenopausal osteoporosis, there is a dramatic increase in the number of osteoclasts with the decline of circulating estrogens. IL-6 is again thought to play a significant role in the pathogenesis of this process. Estrogens have been shown to inhibit the production of IL-6 from cultured bone marrow stromal and osteoblastic cell lines (93). The inhibitory effect of estrogen on IL-6 production is mediated through inhibition of IL-6 gene transcription via an estrogen-receptor-mediated effect on the transcriptional activity of the proximal 225-ƒÒp sequence of the promoter (94, 95). Studies on IL-6 knockout mice (i.e. mice lacking IL-6) have demonstrated that the presence of IL-6 is essential for the development of postmenopausal osteoporosis. Unlike wild-type mice, IL-6 knockout mice did not show cellular changes in the marrow and trabecular bone sections and were protected from the loss of trabecular bone after the loss of sex steroids (96, 97). TNF-ƒÑ has also been shown to influence bone resorption involved in postmenopausal osteoporosis. One study revealed that augmented production of TNF-ƒÑ by T-cells following ovariectomy led to increased macrophage stimulating factor- (M-CSF) and RANK ligand-induced osteoclastogenesis (98). Furthermore, ovariectomy failed to induce bone loss or stimulate osteoclastogenesis in T-cell deficient nude (without a thymus) mice. The effects of TNF-ƒÑ on bone resorption were then further investigated in TNF knockout mice. Ovariectomy was found to induce rapid bone loss in wild-type mice but failed to do so in TNF-ƒÑ-deficient (TNF-/-) mice. In addition, adoptive transfer of wild type (wt) T cells to T cell-deficient nude mice restored the bone loss induced by ovariectomy in these mice, whereas reconstitution with T cells from TNF-/- mice failed to do so (99). The authors concluded that bone marrow T cells (through production of TNF-ƒÑ) may be playing a major role as mediators of the bone-wasting effects of estrogen deficiency in vivo. The data on IL-6 and TNF-ƒÑ knockout mice are intriguing. It appears that lack of either TNF-ƒÑ or IL-6 is protective against the development of osteoporosis due to sex-steroid deficiency. It is plausible that TNF-ƒÑ stimulates IL-6, which in turn mediates osteoclast bone resorption. TNF-ƒÑ stimulates production of IL-6 by several cell types, including bone marrow stromal cells and osteoblasts (100). IL-6- on the other hand- does not stimulate TNF-ƒÑ secretion (101). Therefore TNF-ƒÑ may be exerting some of its actions through IL-6, which may explain why both TNF-ƒÑ and IL-6 knockout mice show decreased osteoclast-induced bone resorption. Estrogen has been shown to decrease TNF-ƒÑ gene expression by blocking Jun NH(2)-terminal kinase (JNK) activity (102). By blocking JNK, there is decreased phosphorylation of c-Jun and JunD- which are nuclear transcription factors that along with AP-1 help form the initiation complex at the TNF promoter site. This results in the subsequent inhibition of TNF-ƒÑ gene transcription. It appears that an intact p55 TNF receptor-I is necessary for estrogen deficiency-induced osteoporosis. In a recent study, ovariectomy failed to decrease the bone mineral density of P55 knockout mice (99). Besides having a direct role on osteoclastogenesis, TNF-ƒÑ has been shown to inhibit osteoblast differentiation as well. The transcription factor RUNX2 is a critical regulator of osteoblast differentiation. A recent study showed that incubation of fetal calvarial precursor cells with TNF-ƒÑ led to a 50-90% reduction in the expression of all isoforms of RUNX2 mRNA (103). Besides influencing osteoporosis due to estrogen deficiency by itself, TNF-ƒÑ may also influence other cytokines to mediate osteoclast-induced bone resorption. IL-1 is one cytokine that may be influenced by TNF-ƒÑ. IL-1 plays a role in estrogen deficiency-mediated osteoporosis by stimulating osteoclast activity through direct targeting of mature osteoclasts rather than by stimulating osteoclastogenesis like TNF-ƒÑ does. Studies have shown that TNF-ƒÑ neutralization blocks IL-1 production whereas IL-1 neutralization does not block TNF-ƒÑ. Thus it is likely that increased bone marrow levels of IL-1 observed in ovariectomized mice are a result of increased TNF-ƒÑ production. TNF-ƒÑ and IL-1 have also been shown to induce production of IL-7 (104). IL-7 has been shown to influence osteoclastogenesis through T cells by RANK-ligand-dependent and independent mechanisms. It appears that IL-6 and IL-8 play a major role in thyrotoxicosis-induced osteoporosis as well. Besides the effects of IL-6 on bone resorption already mentioned, IL-8 appears to play a role in bone resorption as well with IL-8 receptors being expressed by osteoclasts (105). A rise in IL-6 and IL-8, but not in IL-ƒ¡ƒÒ, IL-11, or TNF-ƒÑ, in patients with thyrotoxicosis due to Graves' disease (Gd) or toxic multinodular goiter (TMNG) has been observed (106). In the same study, patients with thyroid carcinoma (CA) on TSH suppressive therapy had significantly raised circulating levels of IL-6 and IL-8 compared to controls. In both groups of patients plasma levels of IL-6 and IL-8 correlated with serum T3 and free T4 concentrations but not with the bone turnover markers, namely urinary deoxypyridinoline (Udpd) or bone-specific alkaline phosphatase (b-ƒÑLP). Both IL-6 and IL-8 have also been shown to be released by human bone marrow stromal cell cultures containing osteoblast progenitor cells in response to T3 (105). Therefore, the increased plasma concentrations of IL-6 and IL-8 seen in thyrotoxicosis are most likely caused by T3 stimulation of bone osteoblasts despite the inability of bone markers to correlate with acute changes in thyroid hormone status. Bone resorption in primary hyperparathyroidism appears to be mediated by cytokines as well. Cytokines such as IL-6, interleukin-ƒ¡ƒÒ, and TNF-ƒÑ had been examined with respect to their relationship to biochemical markers of bone turnover in patients with primary hyperparathyroidism, hypoparathyroidism, normal controls, and in patients who had undergone parathyroid adenectomy. IL-6, IL-6 soluble receptor (IL6-sR), and TNF-ƒÑ were all found to be elevated in patients with primary hyperparathyroidism. After parathyroid adenectomy, the circulating levels of each of these cytokines fell into the normal range. The hypoparathyroid patients had lower levels of IL-6, IL-6sR, and TNF-ƒÑ compared to normal controls (107). The cytokine that especially correlated with serum levels of PTH and with biochemical markers of bone resorption- such as serum deoxypyridinoline, type I collagen carboxyterminal telopeptide, urinary pyridinoline, and urinary deoxypyridinoline- was circulating IL-6. Multiple regression analysis further confirmed that IL-6 and not TNF-ƒÑ was independently predictive of bone resorption in these patients. (107). Besides having a direct action on bone resorption, IL-6 may also have an indirect action on bone resorption in hyperparathyroidism by its influence on IL-11. Both IL-6 and IL-11 belong to a family of cytokines that shares the use of gp130 receptor for intracellular signaling (108, 109). In vitro studies have further established that IL-11 plays a prominent role in bone homeostasis. Like IL-6, IL-11 is also produced by osteoblasts in response to osteotropic factors such as PTH and 1,25(OH)2-vitD. In addition, IL-11 has been found to inhibit osteoclast apoptosis and stimulate osteoclast formation (110-112). Although PTH stimulates the production of both cytokines by human osteoblast-like cells, IL-6 has been found to be elevated in hyperparathyroidism, while IL-11 levels were significantly reduced. Also, after parathyroidectomy, circulating levels of IL-6 dropped while those of IL-11 increased. When PTH was infused into rodents, there was a significant decline in mean circulating levels of IL-11, whereas IL-6 levels increased. Furthermore, pretreatment of cells with neutralizing serum to IL-6 enhanced PTH-induced IL-11 production, compared with the effect of pretreatment with non-immune sera. These data indicate that IL-6 negatively regulates IL-11 production in vivo and in vitro. Analysis of steady-state mRNA levels in SaOS-2 cells indicated that this effect is posttranscriptional. Since both IL-6 and IL-11 stimulate osteoclast formation, down-regulation of IL-11 by IL-6 may help modulate the resorptive response to PTH (113). An abtract from: IMMUNE SYSTEM, EFFECTS ON THE ENDOCRINE SYSTEM Chapter 29 - Jason A. Berner, M.D., Dimitris A. Papanicolaou, M.D. March 11, 2003 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2004 Report Share Posted December 22, 2004 Interesting article. So many people in US have osteoporosis. It's good to learn new things. Thanks for sharing! I found that pure milk calcium is a great source for helping osteoporosis people. See below. http://tinyurl.com/6f6dw Regards, David Chee Sum Yeong <ycsum wrote: As we age, our immune system tends to move towards thepro-inflamatory Th2 arm, where many diseases relatedto inflamation begin to manifest and osteoporosisbeing one of them. The pro-inflamatory cytokinr IL-6seems to play a prominent role in most of thesediseases. I strongly believe that an anti-inflamatorydiet together with immune modulating supplement willbe of great help. Below is an abstract from: IMMUNESYSTEM, EFFECTS ON THE ENDOCRINE SYSTEMChapter 29 - Jason A. Berner, M.D., Dimitris A.Papanicolaou, M.D. March 11, 2003:CALCIUM METABOLISM AND THE IMMUNE SYSTEMOsteoporosisOsteoporosis is a disease of bone metabolism typicallyoccurring in postmenopausal women, in which boneresorption is favored over bone formation. The twocells involved in dynamic bone metabolism areosteoblasts and osteoclasts. Osteoblasts function tolay down new bone and osteoclasts function to reabsorbold bone. Cytokines have been implicated in thepathogenesis of osteoporosis. Osteoblasts produce thecytokines IL-6 and IL-11 (78). In addition, manycytokines such as IL-1, IL-3, IL-6, IL-11, and TNFalong with colony stimulating factors are implicatedin osteoclast development (79-82).IL-6 plays a major role in osteoclast development andfunction. IL-6 is produced by both stromal cells andosteoblastic cells in response to stimulation bysystemic hormones such as parathyroid hormone (PTH),PTH-related peptide (PTH-RP), thyroid hormones and1,25-dihydroxyvitamin D3. Growth factors involved inresorption, such as transforming growth factor-ƒÒeta(TGF-ƒÒ), and other cytokines- like IL-1 and TNF-increase IL-6 production as well (83). IL-6 has beenshown to stimulate osteoclast formation and boneresorption in fetal mouse bone in vitro (84, 85) and,along with IL-1, it stimulates bone resorption in vivo(86). Evidence has been shown to suggest that IL-6influences not only immature osteoclasts but matureosteoclasts as well. Human osteoclastoma cells havereceptors for IL-6, which stimulates the resorptiveactivity of these cells (87). Furthermore, IL-6 has been shown to play a role in theabnormal bone resorption observed with multiplemyeloma (88), Paget's disease (89), rheumatoidarthritis (90), and Gorham-Stout disease (91). Effectsof increased osteoclast-induced bone resorption arenot solely reserved to IL-6, but IL-6 familycytokines- such as leukemia-inhibitory factor (LIF) -as well. It appears that LIF acts on osteoclastsindirectly via stimulating IL-6 release byosteoblasts, resulting in an increase in boneresorption (92).In postmenopausal osteoporosis, there is a dramaticincrease in the number of osteoclasts with the declineof circulating estrogens. IL-6 is again thought toplay a significant role in the pathogenesis of thisprocess. Estrogens have been shown to inhibit theproduction of IL-6 from cultured bone marrow stromaland osteoblastic cell lines (93). The inhibitoryeffect of estrogen on IL-6 production is mediatedthrough inhibition of IL-6 gene transcription via anestrogen-receptor-mediated effect on thetranscriptional activity of the proximal 225-ƒÒpsequence of the promoter (94, 95). Studies on IL-6knockout mice (i.e. mice lacking IL-6) havedemonstrated that the presence of IL-6 is essentialfor the development of postmenopausal osteoporosis.Unlike wild-type mice, IL-6 knockout mice did not showcellular changes in the marrow and trabecular bonesections and were protected from the loss oftrabecular bone after the loss of sex steroids (96,97).TNF-ƒÑ has also been shown to influence boneresorption involved in postmenopausal osteoporosis.One study revealed that augmented production of TNF-ƒÑby T-cells following ovariectomy led to increasedmacrophage stimulating factor- (M-CSF) and RANKligand-induced osteoclastogenesis (98). Furthermore,ovariectomy failed to induce bone loss or stimulateosteoclastogenesis in T-cell deficient nude (without athymus) mice. The effects of TNF-ƒÑ on bone resorptionwere then further investigated in TNF knockout mice.Ovariectomy was found to induce rapid bone loss inwild-type mice but failed to do so in TNF-ƒÑ-deficient(TNF-/-) mice. In addition, adoptive transfer of wildtype (wt) T cells to T cell-deficient nude micerestored the bone loss induced by ovariectomy in thesemice, whereas reconstitution with T cells from TNF-/-mice failed to do so (99). The authors concluded thatbone marrow T cells (through production of TNF-ƒÑ) maybe playing a major role as mediators of thebone-wasting effects of estrogen deficiency in vivo.The data on IL-6 and TNF-ƒÑ knockout mice areintriguing. It appears that lack of either TNF-ƒÑ orIL-6 is protective against the development ofosteoporosis due to sex-steroid deficiency. It isplausible that TNF-ƒÑ stimulates IL-6, which in turnmediates osteoclast bone resorption. TNF-ƒÑ stimulatesproduction of IL-6 by several cell types, includingbone marrow stromal cells and osteoblasts (100). IL-6-on the other hand- does not stimulate TNF-ƒÑ secretion(101). Therefore TNF-ƒÑ may be exerting some of itsactions through IL-6, which may explain why bothTNF-ƒÑ and IL-6 knockout mice show decreasedosteoclast-induced bone resorption.Estrogen has been shown to decrease TNF-ƒÑ geneexpression by blocking Jun NH(2)-terminal kinase (JNK)activity (102). By blocking JNK, there is decreasedphosphorylation of c-Jun and JunD- which are nucleartranscription factors that along with AP-1 help formthe initiation complex at the TNF promoter site. Thisresults in the subsequent inhibition of TNF-ƒÑ genetranscription. It appears that an intact p55 TNFreceptor-I is necessary for estrogendeficiency-induced osteoporosis. In a recent study,ovariectomy failed to decrease the bone mineraldensity of P55 knockout mice (99).Besides having a direct role on osteoclastogenesis,TNF-ƒÑ has been shown to inhibit osteoblastdifferentiation as well. The transcription factorRUNX2 is a critical regulator of osteoblastdifferentiation. A recent study showed that incubationof fetal calvarial precursor cells with TNF-ƒÑ led toa 50-90% reduction in the expression of all isoformsof RUNX2 mRNA (103).Besides influencing osteoporosis due to estrogendeficiency by itself, TNF-ƒÑ may also influence othercytokines to mediate osteoclast-induced boneresorption. IL-1 is one cytokine that may beinfluenced by TNF-ƒÑ. IL-1 plays a role in estrogendeficiency-mediated osteoporosis by stimulatingosteoclast activity through direct targeting of matureosteoclasts rather than by stimulatingosteoclastogenesis like TNF-ƒÑ does. Studies haveshown that TNF-ƒÑ neutralization blocks IL-1production whereas IL-1 neutralization does not blockTNF-ƒÑ. Thus it is likely that increased bone marrowlevels of IL-1 observed in ovariectomized mice are aresult of increased TNF-ƒÑ production. TNF-ƒÑ and IL-1have also been shown to induce production of IL-7(104). IL-7 has been shown to influenceosteoclastogenesis through T cells byRANK-ligand-dependent and independent mechanisms.It appears that IL-6 and IL-8 play a major role inthyrotoxicosis-induced osteoporosis as well. Besidesthe effects of IL-6 on bone resorption alreadymentioned, IL-8 appears to play a role in boneresorption as well with IL-8 receptors being expressedby osteoclasts (105). A rise in IL-6 and IL-8, but notin IL-ƒ¡ƒÒ, IL-11, or TNF-ƒÑ, in patients withthyrotoxicosis due to Graves' disease (Gd) or toxicmultinodular goiter (TMNG) has been observed (106). Inthe same study, patients with thyroid carcinoma (CA)on TSH suppressive therapy had significantly raisedcirculating levels of IL-6 and IL-8 compared tocontrols. In both groups of patients plasma levels ofIL-6 and IL-8 correlated with serum T3 and free T4concentrations but not with the bone turnover markers,namely urinary deoxypyridinoline (Udpd) orbone-specific alkaline phosphatase (b-ƒÑLP). Both IL-6and IL-8 have also been shown to be released by humanbone marrow stromal cell cultures containingosteoblast progenitor cells in response to T3 (105).Therefore, the increased plasma concentrations of IL-6and IL-8 seen in thyrotoxicosis are most likely causedby T3 stimulation of bone osteoblasts despite theinability of bone markers to correlate with acutechanges in thyroid hormone status.Bone resorption in primary hyperparathyroidism appearsto be mediated by cytokines as well. Cytokines such asIL-6, interleukin-ƒ¡ƒÒ, and TNF-ƒÑ had been examinedwith respect to their relationship to biochemicalmarkers of bone turnover in patients with primaryhyperparathyroidism, hypoparathyroidism, normalcontrols, and in patients who had undergoneparathyroid adenectomy. IL-6, IL-6 soluble receptor(IL6-sR), and TNF-ƒÑ were all found to be elevated inpatients with primary hyperparathyroidism. Afterparathyroid adenectomy, the circulating levels of eachof these cytokines fell into the normal range. Thehypoparathyroid patients had lower levels of IL-6,IL-6sR, and TNF-ƒÑ compared to normal controls (107).The cytokine that especially correlated with serumlevels of PTH and with biochemical markers of boneresorption- such as serum deoxypyridinoline, type Icollagen carboxyterminal telopeptide, urinarypyridinoline, and urinary deoxypyridinoline- wascirculating IL-6. Multiple regression analysis furtherconfirmed that IL-6 and not TNF-ƒÑ was independentlypredictive of bone resorption in these patients.(107).Besides having a direct action on bone resorption,IL-6 may also have an indirect action on boneresorption in hyperparathyroidism by its influence onIL-11. Both IL-6 and IL-11 belong to a family ofcytokines that shares the use of gp130 receptor forintracellular signaling (108, 109). In vitro studieshave further established that IL-11 plays a prominentrole in bone homeostasis. Like IL-6, IL-11 is alsoproduced by osteoblasts in response to osteotropicfactors such as PTH and 1,25(OH)2-vitD. In addition,IL-11 has been found to inhibit osteoclast apoptosisand stimulate osteoclast formation (110-112). AlthoughPTH stimulates the production of both cytokines byhuman osteoblast-like cells, IL-6 has been found to beelevated in hyperparathyroidism, while IL-11 levelswere significantly reduced. Also, afterparathyroidectomy, circulating levels of IL-6 droppedwhile those of IL-11 increased. When PTH was infusedinto rodents, there was a significant decline in meancirculating levels of IL-11, whereas IL-6 levelsincreased. Furthermore, pretreatment of cells withneutralizing serum to IL-6 enhanced PTH-induced IL-11production, compared with the effect of pretreatmentwith non-immune sera. These data indicate that IL-6negatively regulates IL-11 production in vivo and invitro. Analysis of steady-state mRNA levels in SaOS-2cells indicated that this effect isposttranscriptional. Since both IL-6 and IL-11stimulate osteoclast formation, down-regulation ofIL-11 by IL-6 may help modulate the resorptiveresponse to PTH (113).An abtract from:IMMUNE SYSTEM, EFFECTS ON THE ENDOCRINE SYSTEMChapter 29 - Jason A. Berner, M.D., Dimitris A.Papanicolaou, M.D. March 11, 2003 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 22, 2004 Report Share Posted December 22, 2004 " bta1012003 " <bta101 How very interesting. Thank you very much for sharing your experience. I appreciate it. I will look for the red yeast rice capsule. Is this something a health food store would carry? ============================================ A HFS may have it, but be aware there is more than one form of red yeast rice, so read the labels. Most are for the lowering of cholesterol, which won’t do much for your bones. If you want the one for bone health, make sure it says somewhere on the label “restores bone” or ”bone support” or “certified bone active by the International Bone Lab” or something to that effect. Carol Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 1, 2005 Report Share Posted March 1, 2005 I had osteopenia a few years ago, which means I was on my way to osteoporosis. My bones didn’t improve until I eliminated my 3 glasses of milk a day, eliminated most cheese and other dairy, eliminated my calcium pills, eliminated most meat, added calcium-rich veggies, and added wholefood supplements that are naturally high in minerals. It took a while, but my latest bone scan shows that I now have bones like a 25 year old woman, and I am more than twice that age. Carol ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Would you benefit from a more effective and healthy immune system? Organic, wholefood, supplements provide nutrients essential for the health of people, pets and plants. http://www.bluegreensolutions.com ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 12, 2006 Report Share Posted November 12, 2006 _http://www.betterbones.com/index.htm_ (http://www.betterbones.com/index.htm) Lots of information there. Best of luck! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 12, 2006 Report Share Posted November 12, 2006 Hi, Last April I was diagnosed with osteoporosis in my spine and hips. I've always been very active. Professional ballet dancer into my late 20's, then went to training dressage horses in my time away from my regular job, so exercise is not a problem. Have also always gotten plenty of calcium in my diet and with supplements. Osteoporosis is hereditary for me, my 87 year old Mom has had both kyphoplasty and vertebraplasty for compression fractures in her spine, and her Mom had a severe " dowager's hump " . I'm now taking Actonel and was wondering if anybody on this group has any alternative ideas to go along with what I'm already doing. Knowledge is power and I definitely need all the knowlege on this that I can accumulate. Naomi Quote Link to comment Share on other sites More sharing options...
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