Growth Promoters in Beef have Estrogenic effect on Cancerous cells

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Growth Promoters in Beef have Estrogenic effect on Cancerous cells

Aug 02, 2003 21:07 PDT

 

 

 

Residual amounts of the growth promoter Zeranol, used in beef

cattle,

may have an estrogenic effect on the growth of normal and cancerous

breast cells in humans, Ohio researchers reported here at the " Era

of

Hope " Department of Defense Breast Cancer Research Program Meeting.

 

Dr. Young C. Lin, of the Comprehensive Cancer Center at Ohio State

University, in Columbus, tested serum, muscle tissue, and adipose

tissue

of cattle exposed to Zeranol in culture with normal and cancerous

human

breast cells. They found that serum, muscle extract, and adipose

extract

significantly elevated DNA synthesis in normal cells, with adipose

extract 2.5 times more potent than muscle extract. Serum stimulated

DNA

synthesis in one of two cancerous cell lines tested.

 

" The greater mitogenic potency of Zeranol-adipose extract versus

Zeranol-meat extract indicates the presence of other unidentified

factors that may contribute to effects on breast tissue, " Dr. Lin's

team

wrote in a meeting abstract. " The lack of growth response in [one

cancerous cell line] to Zeranol-serum indicates dependence on

estrogen

receptors for mitogenic activity. "

 

" We must be very cautious at this stage, " Dr. Lin said. " At this

point

all we have done is define that this factor is capable of mimicking

estrogenic action in gene amplification. In other words, these

compounds

act like estrogen at the molecular level, but we have no reason to

believe they are harmful to the consumer. Diet studies need to be

done

in vivo, say in mice, to see how or if the digestive process affects

this chemical's action. "

 

" The FDA-approved levels of Zeranol are 150 ppb (parts per billion)

for

meat, 300 ppb for liver, 450 ppb for kidney and 600 ppb for fat

tissue, "

Dr. Lin told Reuters Health. " Our laboratory samples had much lower

concentrations, 0.34 ppb in our 1% solution. " Dr. Lin again stressed

that these were laboratory samples developed and monitored under

ideal

conditions.

 

Ann's NOTE: Many of us suspect that hormones added to meat causes

problems. This study indicates that scientists can track this. The

hormone appears to act as a promoter of breast cell growth.

 

Thanks to Reuters Health (Downloaded from Oncolink-U of Penn).

 

http://www.annieappleseedproject.org/beefadcelsti.html